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AFM Gene

protein-coding   GIFtS: 52

GC04P070158
afamin
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

Aliases &
Descriptions
for AFM gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases & Descriptions
afamin1 2     ALF2
ALB21 2 3 5     MGC1253392
ALBA1 2 3 5     alpha-albumin2
MGC1253382     Alpha-albumin3
alpha-Alb2     Alpha-Alb3

External Ids:    HGNC: 3161   Entrez Gene: 1732   Ensembl: ENSG000000795577   UniProtKB: P436523   

Export aliases for AFM gene to outside databases

Previous GC identifers: GC04P074336 GC04P074587 GC04P074748 GC04P074813 GC04P074712 GC04P074566


Summaries
for AFM gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for AFM:
This gene is a member of the albumin gene family, which is comprised of four genes that localize to chromosome 4 in a
tandem arrangement. These four genes encode structurally-related serum transport proteins that are known to be
evolutionarily related. The protein encoded by this gene is regulated developmentally, expressed in the liver and
secreted into the bloodstream. (provided by RefSeq)

UniProtKB/Swiss-Prot: AFAM_HUMAN, P43652
Function: Possible role in the transport of yet unknown ligand

Gene Wiki entry for AFM

Genomic Views
for AFM gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the AFM gene promoter:
         CUTL1   HNF-1A   MEF-2A   FOXO3a   FOXO3b   Nkx6-1   MRF-2   C/EBPbeta   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for AFM

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q13.3   Ensembl cytogenetic band:  4q13.3   HGNC cytogenetic band: 4q13.3

AFM Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AFM gene location

GeneLoc gene densities for chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P070158:  view genomic region     (about GC identifiers)

Start:
 70,158,855 bp from pter
End:
 70,181,099 bp from pter
Size:
 22,245 bases
Orientation:
 plus strand

1 alternative location:
Chr4+ 74,347,400-74,369,691     
RefSeq DNA sequence:
NC_000004.11  NT_022778.16  

Proteins
for AFM gene

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section
UniProtKB/Swiss-Prot: AFAM_HUMAN, P43652 (See protein sequence)
Recommended Name: Afamin precursor  
Size: 599 amino acids; 69069 Da
Subcellular location: Secreted
Secondary accessions: A8K3E1 Q32MR3

Explore the universe of human proteins at neXtProt for AFM: NX_P43652 

Post-translational modifications:

  • N-glycosylated1
  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins: NP_001124.1  

    ENSEMBL proteins: 
    ENSP00000226355 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
    Sigma-Aldrich AQUA Peptides for AFM
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    GenScript Custom Purified and Recombinant Proteins Services for AFM 
    Novus Biologicals Protein for AFM
    Novus Biologicals Lysate for AFM
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins

    2 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576 extracellular region IEA--
    GO:0005615 extracellular space IEA--
    About this table

    AFM for ontologies           About GeneDecksing



    Antibodies for AFM: 
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for AFM
    Browse R&D Systems for Antibodies
    Cell Signaling Technology (CST) Antibodies for AFM 
    OriGene Antibodies: AFM
    GenScript Custom Superior Antibodies Services for AFM 
    Novus Biologicals Antibody for AFM
    Browse antibodies at Epitomics

    Assays for AFM: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for AFM 
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for AFM 

    Protein Domains/
    Families
    for AFM gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    AFM for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR000264 Serum_albumin
     IPR014760 Serum_albumin_N
     IPR020858 Serum_albumin-like
     IPR001703 Alpha-fetoprotein
     IPR020857 Serum_albumin_CS

    Graphical View of Domain Structure for InterPro Entry P43652

    ProtoNet protein and cluster: P43652

    1 Blocks protein family: IPB000264 Serum albumin family

    UniProtKB/Swiss-Prot: AFAM_HUMAN, P43652
    Similarity: Belongs to the ALB/AFP/VDB family
    Similarity: Contains 3 albumin domains


    Gene Function
    for AFM gene

    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    UniProtKB/Swiss-Prot: AFAM_HUMAN, P43652
    Function: Possible role in the transport of yet unknown ligand

    Inhib.
    RNA:            		Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich siRNA Panels and esiRNA and siRNA for AFM
    Sigma-Aldrich shRNA for AFM
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): AFM
    OriGene shRNA RFP (see all 2): AFM
    OriGene basic RS shRNA (see all 2): AFM
    OriGene siRNA: AFM
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of AFM 
    miRNA:Sigma-Aldrich microRNA Mimics for AFM
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of AFM 
    1 SABiosciences Assays for microRNA that regulate AFM:
    hsa-miR-137

    Gene
    Editing:    		Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: AFM
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: AFM
    OriGene untagged cDNA clones in CMV expression vector (see all 2): AFM
    OriGene 3'-UTR clone: AFM 
    Browse MicroRNA Expression Plasmids 
    GenScript cDNA clone with any tag delivered in your preferred vector: AFM 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:          		GenScript Custom overexpressing Cell Line Services for AFM 

    Genatlas biochemistry entry for AFM:
    afamin,87kDa,albumin superfamily

    Pathways & Interactions
    for AFM gene

    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section

        SABiosciences Custom Pathway-Focused PCR Arrays for AFM 

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AFM

    1 Gene Ontology (GO) biological process term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810 transport IEA--
    About this table

    AFM for ontologies           About GeneDecksing



    Drugs & Compounds
    for AFM gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    AFM for compounds           About GeneDecksing

    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for AFM
    3 Novoseek chemical compound relationships for AFM gene
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    vitamin-e 61.8 16 12463752 (3), 12456077 (3), 15952736 (2), 18094419 (1)
    vitamin d 52.1 9 10400926 (1), 16489915 (1), 19733224 (1), 17654119 (1) (see all 5)
    alpha tocopherol 50.4 18 19046407 (4), 12463752 (1), 12456077 (1)
    About this table



    Transcripts
    for AFM gene

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section
    Inhib.
    RNA:             		Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich siRNA Panels and esiRNA and siRNA for AFM
    Sigma-Aldrich shRNA for AFM
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): AFM
    OriGene shRNA RFP (see all 2): AFM
    OriGene basic RS shRNA (see all 2): AFM
    OriGene siRNA: AFM
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of AFM 
    miRNA: Sigma-Aldrich microRNA Mimics for AFM
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of AFM 
    1 SABiosciences Assays for microRNA that regulate AFM:
    hsa-miR-137
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: AFM
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: AFM
    OriGene untagged cDNA clones in CMV expression vector (see all 2): AFM
    OriGene 3'-UTR Clone: AFM 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript cDNA clone with any tag delivered in your preferred vector: AFM 
    Primers: OriGene genome-wide validated SYBR primer pairs: AFM
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for AFM: PPH13377A

    REFSEQ mRNAs for AFM gene: 

    NM_001133.2  

    Additional cDNA sequence: 

    AK290556.1 BC109020.1 BC109021.1 L35498.1 

    6 DOTS entries:

    DT.208928  DT.202804  DT.75100220  DT.91948823  DT.92422309  DT.92422310 

    24/31 AceView cDNA sequences (see all 31):

    L35497 AW235536 NM_001133 BX103962 AI247575 L35486 BX110719 CB157386 
    BF197337 AA878846 L35498 BF434245 AW051948 AI671722 AI492289 AH003117 
    AA706914 CB162042 T67570 T67409 L32140 AI670879 AA501625 AV694104 

    highest scoring ESTs for AFM:

    AA878846 AW051948 AW235536 BF197337 BF434245 BF511963 CB157386 L32140 L35498 T67409 

    Unigene Cluster for AFM:

    Afamin
    Hs.168718  [show with all ESTs]
    Unigene Representative Sequence: NM_001133


    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for AFM

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b ^ 14 ^ 15 ^ 16
    SP1:                    -                                   -                                                               
    SP2:                                                                                                                        
    SP3:                                                                                                                        
    SP4:                                                                          -                                             

    About this scheme

    ECgene alternative splicing isoforms for AFM
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000226355(uc003hhb.2) ENST00000505794

    Expression
    for AFM gene

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    AFM expression in normal and diseased human tissues

    1  / 2  / 3

    4 probe-sets matching AFM gene

    Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    33564_at2, 3 U95-A 1 0.62 1.00 0.99 1.06 L32140 0.80 1.00 0.91 1
    83294_at2, 3 U95-D 1 0.44 1.00 0.98 1.03 AI671722 0.60 1.00 0.82 1
    206840_at2, 3 U133-A 1 0.73 1.00 -- -- NM_001133 0.60 1.00 0.82 1
    206840_at2 U133Plus2 1 0.73 1.00 -- -- -- -- -- -- --
    About this table

    AFM for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    AFM gene expression
    AFM gene electronic northern expression
    AFM gene sage expression
    About these images

    CGAP SAGE TAG: AACTCACAGA

    SOURCE GeneReport for Unigene cluster: Hs.168718

    Expression variation in blood from EXPOLDB for AFM

    Primers: OriGene genome-wide validated SYBR primer pairs: AFM
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for AFM: PPH13377A
        SABiosciences Custom PCR Arrays for AFM 


    Orthologs
    for AFM gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for AFM gene from 5 species
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 AFM1   -- afamin 82.75(n)
    75.21(a)    		 475175  XM_532408.2  XP_532408.2 
    chimpanzee
    (Pan troglodytes)    		 AFM1   -- afamin 99.44(n)
    99(a)    		 461256  XM_517229.2  XP_517229.2 
    cow
    (Bos taurus)    		 AFM1   -- afamin 83.98(n)
    75.71(a)    		 508264  XM_585019.3  XP_585019.2 
    rat
    (Rattus norvegicus)    		 Afm1   -- afamin 76.74(n)
    67.95(a)    		 282708  NM_172320.1  NP_758823.1 
    mouse
    (Mus musculus)    		 Afm1 , 5 5 (44.78 cM)5
    		 afamin1, 5 76.96(n)1
    67.78(a)1    		 2806621  NM_145146.21  NP_660128.21 
     AI2558255  AI3263875  (see all 9)
    About this table        Species with no ortholog for AFM

    ENSEMBL Gene Tree for AFM (if available)

    Paralogs
    for AFM gene

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
    Paralogs for AFM gene
    ALB2  GC2  AFP2  

    AFM for paralogs           About GeneDecksing



    Genomic Variants
    for AFM gene

    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/243 NCBI SNPs in AFM are shown (see all 243)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 4 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ----------
    rs11581011,2
    		C,F,O,A,74363282(+) AGAAAT/CAAGAA 1 -- int117Minor allele frequency- C:0.24NA EA NS WA 926
    rs11596241,2
    		C,F,A,H,74367706(+) CCCTGC/TAGGAC 1 -- int119Minor allele frequency- T:0.33NA EA MN WA 2744
    rs18942921,2
    		C,F,O,A,74349158(+) TTAGTG/ATATGC 1 -- int127Minor allele frequency- A:0.40NA EA MN NS WA 1994
    rs18942931,2
    		C,F,O,A,H,74352022(+) TAATTA/GGTAAG 1 -- int115Minor allele frequency- G:0.38EA NA WA 1940
    rs20403541,2
    		C,F,A,74367100(+) TTGTAC/TTGGGA 1 -- int17Minor allele frequency- T:0.39EA NA WA 1530
    rs20710971,2
    		C,F,O,A,H,74369298(+) TTTACG/ATGAAC 1 -- int119Minor allele frequency- A:0.34EA NA NS WA 2446
    rs20710981,2
    		C,F,O,74352916(+) CATATA/GTGATG 1 -- int121Minor allele frequency- N:0.00EA NA NS WA 2740
    rs22693641,2
    		H74351488(+) TAATGG/CTGGGA 1 -- int15Minor allele frequency- C:0.01EA NS 1916
    rs22764441,2
    		C,F,H74363387(+) ATGAGA/TCAACT 2 T S ref1 mis1 ese38Minor allele frequency- T:0.02NS EA 836
    rs37656391,2
    		C,F,74347771(+) TTACCA/GAGTCT 1 -- int112Minor allele frequency- G:0.31EA NA WA 2010
    About this table

    HapMap Linkage Disequilibrium images for AFM (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for AFM: --

    QIAGEN SeqTarget long-range PCR primers for resequencing AFM 

    Disorders & Mutations
    for AFM gene

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    AFM for disorders           About GeneDecksing

    OMIM: 104145


    Export disorders and mutations for AFM gene to outside databases

    Medical News
    for AFM gene

    (Possibly Related Articles in Doctor's Guide)
    About This Section
    		   --

    Publications
    for AFM gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/37 PubMed articles for AFM gene, integrated from 7 sources (see all 37):
    (articles sorted by number of sources associating them with AFM)
    1. Afamin is a new member of the albumin, alpha-fetoprotein, and vitamin D-binding protein gene family. (PubMed id 7517938)1, 2, 3, 7 Lichenstein H.S....Zukowski M.M. (1994)
    2. Complete structure of the human alpha-albumin gene, a new member of the serum albumin multigene family. (PubMed id 8755513)1, 2, 7 Nishio H. and Dugaiczyk A. (1996)
    3. Identification of rat alpha-albumin and cDNA cloning of its human ortholog. (PubMed id 7875606)1, 2, 7 Allard D.... Belanger L. (1995)
    4. Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry. (PubMed id 16740002)1, 2 Ramachandran P....Loo J.A. (2006)
    5. Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)1, 2 Liu T.... Smith R.D. (2005)
    6. Screening for N-glycosylated proteins by liquid chromatography mass spectrometry. (PubMed id 14760718)1, 2 Bunkenborg J.... Wisniewski J.R. (2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Afamin and apolipoprotein A-IV: novel protein markers for ovarian cancer. (PubMed id 19336561)1, 7 Dieplinger H....Stieber P. (2009)
    9. Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression. (PubMed id 15952736)1, 7 Jerkovic L....Dieplinger H. (2005)
    10. Afamin is synthesized by cerebrovascular endothelial cells and mediates alpha-tocopherol transport across an in vitro model of the blood-brain barrier. (PubMed id 19046407)1, 7 Kratzer I....Sattler W. (2009)

    External Searches for AFM gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing AFM gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 173 HGNC: 316 AceView: AFM Ensembl:ENSG00000079557 euGenes: HUgn173
    ECgene: AFM H-InvDB: AFM

    Other Databases showing AFM gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing AFM gene

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    		   --

    Intellectual Property
    for AFM gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
    About This Section
    		Patent Information for AFM gene:
    Search GeneIP for patents involving AFM

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for AFM gene

    (Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
    Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
    About This Section

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services

     Predesigned and custom siRNAs for AFM Antibodies for AFM
     Super-pooled esiRNAs for AFM Proteins for AFM
     Lentivirus-delivered shRNAs for AFM microRNA Mimics for AFM
     "Your Favorite Gene" Pathways and Molecular Interaction Networks Browse Nano Scale siRNA at Sigma-Aldrich
     Browse iPSC Reprogramming Factors at Sigma-Aldrich Browse small molecules at Sigma-Aldrich
     Browse FLAG tag genes at Sigma-Aldrich Browse ELISAs at Sigma-Aldrich
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