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AHCTF1 Gene

protein-coding   GIFtS: 49

GC01M217396
AT hook containing transcription factor 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
AT hook containing transcription factor 11 2     MST1082
ELYS1 2 3 5     OTTHUMP000000384192
Putative AT-hook-containing transcription factor 12 3     ELYS transcription factor-like protein TMBS622
Embryonic large molecule derived from yolk sac2 3     DKFZp434N0932
TMBS622 3     ELYS transcription factor like protein TMBS622
protein ELYS2     Protein MEL-283
OTTHUMP000000384182     

External Ids:    HGNC: 246181   Entrez Gene: 259092   Ensembl: ENSG000001532077   UniProtKB: Q8WYP53   

Export aliases for AHCTF1 gene to outside databases

Previous GC identifers: GC01M243329 GC01M245069 GC01M247002


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: ELYS_HUMAN, Q8WYP5
Function: Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei
form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex
of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during
mitosis and for the completion of cytokinesis

Gene Wiki entry for AHCTF1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the AHCTF1 gene promoter:
         E4BP4   Hlf   Nkx6-1   Cart-1   STAT3   FOXC1   RORalpha1   MIF-1   STAT1   STAT1beta   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for AHCTF1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for AHCTF1 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q44   Ensembl cytogenetic band:  1q44   HGNC cytogenetic band: 1q44

AHCTF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AHCTF1 gene location

GeneLoc gene densities for chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M217396:  view genomic region     (about GC identifiers)

Start:
217,396,102 bp from pter
End:
217,488,405 bp from pter
Size:
92,304 bases
Orientation:
minus strand

1 alternative location:
Chr1- 247,002,400-247,095,499     
RefSeq DNA sequence:
NC_000001.10  NT_167186.1  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: ELYS_HUMAN, Q8WYP5 (See protein sequence)
Recommended Name: Protein ELYS  
Size: 2266 amino acids; 252498 Da
Subunit: Associates with the Nup107-160 subcomplex of the NPC
Subcellular location: Cytoplasm (By similarity). Nucleus matrix (By similarity). Chromosome, centromere, kinetochore.
Nucleus, nucleoplasm. Nucleus, nuclear pore complex. Note=Localizes to the nuclear pore complex (NPC) throughout
interphase. Localizes to the kinetochore from prophase, and this appears to require the Nup107-160 subcomplex of the
NPC. Localizes to the periphery of chromatin from late anaphase
Sequence caution: Sequence=AAN65622.1; Type=Frameshift; Positions=Several; Sequence=AAQ13621.1; Type=Erroneous
initiation;
Secondary accessions: A6NGM0 A8MSG9 A8MZ86 Q7Z4E3 Q8IZA4 Q96EH9 Q9Y4Q6
Alternative splicing: 2 isoforms:  Q8WYP5-1   Q8WYP5-2   

Explore the universe of human proteins at neXtProt for AHCTF1: NX_Q8WYP5 

Post-translational modifications:

  • Phosphorylated upon DNA damage, probably by ATM or ATR1
  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_056261.4  

    ENSEMBL proteins: 
    ENSP00000283201 ENSP00000355465 ENSP00000417115 ENSP00000418007 ENSP00000375705 ENSP00000394728 
    ENSP00000355464 ENSP00000354780 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    GenScript Custom Purified and Recombinant Proteins Services for AHCTF1 
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins

    5/11 Gene Ontology (GO) cellular component terms (GO ID links to tree view) (see all 11):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000777colocalizes with condensed chromosome kinetochore IDA17098863
    GO:0000785colocalizes with chromatin IDA17098863
    GO:0005634 nucleus IDA18029348
    GO:0005643colocalizes with nuclear pore IDA17098863
    GO:0005654 nucleoplasm IEA--
    About this table

    AHCTF1 for ontologies           About GeneDecksing



    Antibodies for AHCTF1: 
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for AHCTF1
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    GenScript Custom Superior Antibodies Services for AHCTF1 
    Novus Biologicals Antibody for AHCTF1
    Browse antibodies at Epitomics

    Assays for AHCTF1: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for AHCTF1 
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for AHCTF1 


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    AHCTF1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR017956 AT_hook_DNA-bd_motif

    Graphical View of Domain Structure for InterPro Entry Q8WYP5

    ProtoNet protein and cluster: Q8WYP5

    UniProtKB/Swiss-Prot: ELYS_HUMAN, Q8WYP5
    Similarity: Belongs to the ELYS family
    Similarity: Contains 1 A.T hook DNA-binding domain


    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    UniProtKB/Swiss-Prot: ELYS_HUMAN, Q8WYP5
    Function: Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei
    form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex
    of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during
    mitosis and for the completion of cytokinesis

    Inhib.
    RNA:
        
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for AHCTF1
    Sigma-Aldrich shRNA for AHCTF1
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 4): AHCTF1
    OriGene shRNA RFP (see all 4): AHCTF1
    OriGene basic RS shRNA (see all 4): AHCTF1
    OriGene siRNA: AHCTF1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of AHCTF1 
    miRNA:Sigma-Aldrich microRNA Mimics for AHCTF1
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of AHCTF1 
    8/22 SABiosciences Assays for microRNAs that regulate AHCTF1 (see all 22):
    hsa-miR-520d-5p hsa-let-7d hsa-let-7c hsa-miR-944 hsa-miR-410 hsa-let-7g hsa-let-7a hsa-miR-548c-3p

    Gene
    Editing:
    Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: AHCTF1
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: AHCTF1
    OriGene untagged cDNA clones in CMV expression vector: AHCTF1
    OriGene 3'-UTR clone: AHCTF1 
    Browse MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for AHCTF1 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:
      
    GenScript Custom overexpressing Cell Line Services for AHCTF1 

    2 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677 DNA binding IEA--
    GO:0003700 sequence-specific DNA binding transcription factor activity IEA--
    About this table

    AHCTF1 for ontologies           About GeneDecksing

    Animal Models: 2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ahctf1):

    embryogenesislethality-prenatal/perinatal

    AHCTF1 for phenotypes           About GeneDecksing


    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section

        SABiosciences Custom Pathway-Focused PCR Arrays for AHCTF1 

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AHCTF1

    5/83 Interacting proteins for AHCTF1 (ENSP000002832013 Q8WYP52) via UniProtKB, MINT, and/or STRING (see all 83)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NUP107P577402STRING: ENSP00000229179 MINT-4301709 MINT-4301750 MINT-4301632 MINT-4301665
    NUP160Q127692STRING: ENSP00000367721 MINT-4301654 MINT-4301750 MINT-4301592
    NUP133Q8WUM02STRING: ENSP00000261396 MINT-4301609
    RANBP2P497922STRING: ENSP00000283195 MINT-4301750
    NUP62P371982MINT-4301750 MINT-4301693
    About this table

    5/10 Gene Ontology (GO) biological process terms (GO ID links to tree view) (see all 10):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000087 M phase of mitotic cell cycle TAS--
    GO:0000236 mitotic prometaphase TAS--
    GO:0000278 mitotic cell cycle TAS--
    GO:0000910 cytokinesis IMP17098863
    GO:0007049 cell cycle ----
    About this table

    AHCTF1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section
    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for AHCTF1


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section

    Inhib.
    RNA:
         
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for AHCTF1
    Sigma-Aldrich shRNA for AHCTF1
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 4): AHCTF1
    OriGene shRNA RFP (see all 4): AHCTF1
    OriGene basic RS shRNA (see all 4): AHCTF1
    OriGene siRNA: AHCTF1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of AHCTF1 
    miRNA: Sigma-Aldrich microRNA Mimics for AHCTF1
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of AHCTF1 
    8/22 SABiosciences Assays for microRNAs that regulate AHCTF1 (see all 22):
    hsa-miR-520d-5p hsa-let-7d hsa-let-7c hsa-miR-944 hsa-miR-410 hsa-let-7g hsa-let-7a hsa-miR-548c-3p
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: AHCTF1
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: AHCTF1
    OriGene untagged cDNA clones in CMV expression vector: AHCTF1
    OriGene 3'-UTR Clone: AHCTF1 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for AHCTF1 
    Primers: OriGene genome-wide validated SYBR primer pairs: AHCTF1
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for AHCTF1: PPH08995A

    REFSEQ mRNAs for AHCTF1 gene: 

    NM_015446.4  

    Additional cDNA sequence: 

    AB059277.1 AK057394.1 AK122844.1 

    17 DOTS entries:

    DT.100722077  DT.455576  DT.100782663  DT.100782662  DT.121003283  DT.213897  DT.100782667  DT.91754159 
    DT.121003264  DT.213896  DT.91768609  DT.100735543  DT.100782664  DT.100782665  DT.121421286  DT.92045421 
    DT.95270397 

    24/208 AceView cDNA sequences (see all 208):

    BM561545 AI678529 AA761156 AW440376 BM467863 AI374620 BC012307 AA748759 
    BF062340 AL041058 AA635850 CA749031 AW630710 AW627377 BM711248 AL522811 
    AK122844 AI699728 AV703690 AK095398 AI400688 BC047361 BM968234 AL080144 

    highest scoring ESTs for AHCTF1:

    AI374620 AY157619 AA433921 AA434605 AA634114 AB059277 AF173978 AI122864 AI138934 AI351410 

    Unigene Clusters for AHCTF1:

    AT hook containing transcription factor 1
    Hs.300887  [show with all ESTs], Hs.470435  [show with all ESTs]
    Unigene Representative Sequences: NM_015446, AB059277


    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for AHCTF1 (see all 6)

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22a · 22b
    SP1:                                                                    -                                         -                                       
    SP2:                                                                    -                                                                                 
    SP3:                                                                                                                                                      
    SP4:                                                                                                                                                      
    SP5:                                                                                                                                                      

    About this scheme

    ECgene alternative splicing isoforms for AHCTF1
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000283201 ENST00000326225(uc001ibw.1 uc001ibu.1 uc001ibv.1)
    ENST00000478568 ENST00000498601 ENST00000391829 ENST00000483900 ENST00000428671
    ENST00000477526 ENST00000366508 ENST00000470300(uc009xgs.1) ENST00000361182


    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    AHCTF1 expression in normal and diseased human tissues

    1  / 2  / 3

    7 probe-sets matching AHCTF1 gene

    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    61864_at2, 3 U95-C 1 1.00 1.00 0.79 1.09 AI374620 0.80 1.00 0.91 1
    35672_at2, 3 U95-A 2 1.00 0.94 0.57 0.92 AL080144 0.60 1.00 0.82 1
    226115_at2, 3 U133-B 1 1.00 1.00 -- -- AI138934 0.60 1.00 0.82 1
    214766_s_at2, 3 U133-A 2 1.00 0.95 -- -- AL080144 0.60 1.00 0.82 1
    226115_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    214766_s_at2 U133Plus2 2 1.00 0.95 -- -- -- -- -- -- --
    1560224_at2 U133Plus2 2 1.00 0.64 -- -- -- -- -- -- --
    About this table

    AHCTF1 for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    AHCTF1 gene expression
    AHCTF1 gene electronic northern expression
    AHCTF1 gene sage expression
    About these images

    CGAP SAGE TAG: GATGCAACGT TTAGAAGGGT

    SOURCE GeneReport for Unigene clusters: Hs.300887 Hs.470435
    Primers: OriGene genome-wide validated SYBR primer pairs: AHCTF1
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for AHCTF1: PPH08995A
        SABiosciences Custom PCR Arrays for AHCTF1 


    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section

    Orthologs for AHCTF1 gene from 5/9 species (see all 9)
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    AHCTF11   -- AT hook containing transcription factor 1 80.41(n)
    72.38(a)
    480106  XM_537228.2  XP_537228.2 
    chimpanzee
    (Pan troglodytes)
    AHCTF11   -- AT hook containing transcription factor 1 99.09(n)
    98.64(a)
    457874  XM_514319.2  XP_514319.2 
    cow
    (Bos taurus)
    AHCTF11   -- AT hook containing transcription factor 1 86.62(n)
    81.26(a)
    504716  XM_580880.3  XP_580880.3 
    rat
    (Rattus norvegicus)
    Ahctf11   -- AT hook containing transcription factor 1 78.46(n)
    71.36(a)
    360886  XM_341161.3  XP_341162.3 
    mouse
    (Mus musculus)
    Ahctf11 , 5 1 (83.62 cM)5
    AT hook containing transcription factor 11, 5 78.7(n)1
    71.98(a)1
    2267471  NM_026375.11  NP_080651.11 
     AA5444095  AA6929015  (see all 18)
    About this table        Species with no ortholog for AHCTF1

    ENSEMBL Gene Tree for AHCTF1 (if available)

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
      --

    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/37 NCBI SNPs in AHCTF1 are shown (see all 37)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 1 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ----------
    rs10470801,2
    F247004031(-) TTTGGA/GAGAAA 1 -- ut311Minor allele frequency- G:0.06MN 184
    rs10470851,2
    --247004023(-) aaaatA/Cattta 1 -- ut310--------
    rs10539161,2
    C,247002475(-) TTTACA/GTATAT 1 -- ut31 ese30--------
    rs26429901,2
    C,F,A,247048834(+) CATCGC/TTACCA 2 N S ref1 mis110Minor allele frequency- T:0.27NS EA NA WA 430
    rs29965521,2
    C,H,247002694(+) TCATTC/TAACAA 1 -- ut310--------
    rs40115301,2
    --247014178(+) TTGACC/TAATTT 2 L syn1 ref10--------
    rs124105631,2
    C,F,A,H,247006051(+) TCCCAG/CAGTTT 2 /L /V ref1 mis1 ese314Minor allele frequency- C:0.21NS EA NA WA 1052
    rs127337291,2
    --247003398(+) TCAAAC/TCCTTT 1 -- ut31 ese30--------
    rs127338521,2
    --247003438(+) TCAATA/CTAACC 1 -- ut310--------
    rs340046091,2
    --247040356(+) GCACT-/GGGACT 3 S fra1 ref10--------
    About this table

    HapMap Linkage Disequilibrium images for AHCTF1 (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 6 variations for AHCTF1
         3 CNVs: 6816 39040 97715
         3 Indels: 42381 44551 39708

    QIAGEN SeqTarget long-range PCR primers for resequencing AHCTF1 

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    AHCTF1 for disorders           About GeneDecksing

    OMIM: 610853


    Export disorders and mutations for AHCTF1 gene to outside databases

    (Possibly Related Articles in Doctor's Guide)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/18 PubMed articles for AHCTF1 gene, integrated from 7 sources (see all 18):
    (articles sorted by number of sources associating them with AHCTF1)
    1. Identification of a novel transcription factor, ELYS, expressed predominantly in mouse foetal haematopoietic tissues. (PubMed id 11952839)1, 2, 3 Kimura N.... Taga T. (2002)
    2. Phosphoproteome analysis of the human mitotic spindle. (PubMed id 16565220)1, 2 Nousiainen M.... Koerner R. (2006)
    3. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
    4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    5. ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division. (PubMed id 17098863)1, 2 Rasala B.A.... Forbes D.J. (2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (2009)
    8. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
    9. Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)2 Cantin G.T....Yates J.R. III (2008)
    10. Evaluation of the low-specificity protease elastase for large-scale phosphoproteome analysis. (PubMed id 19007248)2 Wang B.... Korner R. (2008)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 25909 HGNC: 24618 AceView: ELYS Ensembl:ENSG00000153207 euGenes: HUgn25909
    ECgene: AHCTF1 H-InvDB: AHCTF1

    (According to HUGE)
    About This Section
      --

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
      --

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
    About This Section
    Patent Information for AHCTF1 gene:
    Search GeneIP for patents involving AHCTF1

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    (Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
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     ELISAs and CLIAs for AHCTF1
           

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