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AIF1L Gene

protein-coding   GIFtS: 47

GC09P103462
allograft inflammatory factor 1-like
(Previous name: chromosome 9 open reading frame 58 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: C9orf58)
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
allograft inflammatory factor 1-like1 2     MGC294662
IBA21 2 3     ionized calcium binding adapter molecule 22
FLJ127831 2     OTTHUMP000000223902
Ionized calcium-binding adapter molecule 22 3     OTTHUMP000000223872
C9orf582 3     OTTHUMP000000223882
chromosome 9 open reading frame 581     

External Ids:    HGNC: 289041   Entrez Gene: 835432   Ensembl: ENSG000001268787   UniProtKB: Q9BQI03   

Export aliases for AIF1L gene to outside databases

Previous GC identifers: GC09P132962 GC09P133971


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: AIF1L_HUMAN, Q9BQI0
Function: Actin-binding protein that promotes actin bundling. May neither bind calcium nor depend on calcium for
function

Gene Wiki entry for AIF1L (C9orf58)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for AIF1L
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for AIF1L

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for AIF1L 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.13-q34.3   Ensembl cytogenetic band:  9q34.12   HGNC cytogenetic band: 9q34.13-q34.3

AIF1L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AIF1L gene location

GeneLoc gene densities for chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P103462:  view genomic region     (about GC identifiers)

Start:
103,462,597 bp from pter
End:
103,489,133 bp from pter
Size:
26,537 bases
Orientation:
plus strand

1 alternative location:
Chr9+ 133,971,912-133,998,539     
RefSeq DNA sequence:
NC_000009.11  NT_035014.4  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: AIF1L_HUMAN, Q9BQI0 (See protein sequence)
Recommended Name: Allograft inflammatory factor 1-like  
Size: 150 amino acids; 17068 Da
Subunit: Homodimer (Potential). Monomer
Subcellular location: Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein;
Cytoplasmic side. Note=Colocalizes with F-actin. Partially relocates to membrane ruffles in response to invading
bacteria
PDB structures from and Proteopedia :
2VTG (3D)    
Secondary accessions: B2RBC4 Q6ZR40 Q8NAX7 Q8WU47 Q9H9G0
Alternative splicing: 4 isoforms:  Q9BQI0-1   Q9BQI0-2   Q9BQI0-3   Q9BQI0-4   

Explore the universe of human proteins at neXtProt for AIF1L: NX_Q9BQI0 

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins (3 alternative transcripts): 
    NP_001172024.1  NP_001172025.1  NP_113614.1  


    ENSEMBL proteins: 
    ENSP00000361375 ENSP00000361388 ENSP00000361372 ENSP00000361376 ENSP00000361371 ENSP00000361393 
    ENSP00000361386 ENSP00000361383 ENSP00000361374 ENSP00000247291 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: AIF1L
    GenScript Custom Purified and Recombinant Proteins Services for AIF1L 
    Novus Biologicals Protein for AIF1L
    Novus Biologicals Lysate for AIF1L
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins

    5/7 Gene Ontology (GO) cellular component terms (GO ID links to tree view) (see all 7):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737 cytoplasm IEA--
    GO:0005884colocalizes with actin filament IDA18699778
    GO:0005886 plasma membrane IEA--
    GO:0005925 focal adhesion IDA11256614
    GO:0015629 actin cytoskeleton IDA11256614
    About this table

    AIF1L for ontologies           About GeneDecksing



    Antibodies for AIF1L: 
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse Antibodies at Sigma-Aldrich
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    GenScript Custom Superior Antibodies Services for AIF1L 
    Novus Biologicals Antibodies for AIF1L
    Browse antibodies at Epitomics

    Assays for AIF1L: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for AIF1L 
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs and CLIAs at Uscn 


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    AIF1L for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR011992 EF-hand-like_dom
     IPR018249 EF_HAND_2

    Graphical View of Domain Structure for InterPro Entry Q9BQI0

    ProtoNet protein and cluster: Q9BQI0

    UniProtKB/Swiss-Prot: AIF1L_HUMAN, Q9BQI0
    Similarity: Contains 2 EF-hand domains


    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    UniProtKB/Swiss-Prot: AIF1L_HUMAN, Q9BQI0
    Function: Actin-binding protein that promotes actin bundling. May neither bind calcium nor depend on calcium for
    function

    Inhib.
    RNA:
        
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich siRNA Panels and esiRNA and siRNA for AIF1L
    Sigma-Aldrich shRNA Panels and shRNA for AIF1L
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): AIF1L
    OriGene shRNA RFP (see all 2): AIF1L
    OriGene basic RS shRNA (see all 2): AIF1L
    OriGene siRNA (see all 2): AIF1L
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of AIF1L 
    miRNA:Sigma-Aldrich microRNA Mimics for AIF1L
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of AIF1L 
    6 SABiosciences Assays for microRNAs that regulate AIF1L:
    hsa-miR-1233 hsa-miR-1321 hsa-miR-124 hsa-miR-129-3p hsa-miR-506 hsa-miR-218

    Gene
    Editing:
    Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: AIF1L
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: AIF1L
    OriGene untagged cDNA clones in CMV expression vector: AIF1L
    OriGene 3'-UTR clone: AIF1L 
    Browse MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for AIF1L 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:
      
    GenScript Custom overexpressing Cell Line Services for AIF1L 

    2 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509 calcium ion binding IEA--
    GO:0051015 actin filament binding IDA18699778
    About this table

    AIF1L for ontologies           About GeneDecksing


    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section

        SABiosciences Custom Pathway-Focused PCR Arrays for AIF1L 

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AIF1L

    1 Interacting protein for AIF1L (Q9BQI02) via UniProtKB, MINT, and/or STRING
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RIPK3Q9Y5722MINT-49121
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section
    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for AIF1L


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section

    Inhib.
    RNA:
         
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich siRNA Panels and esiRNA and siRNA for AIF1L
    Sigma-Aldrich shRNA Panels and shRNA for AIF1L
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): AIF1L
    OriGene shRNA RFP (see all 2): AIF1L
    OriGene basic RS shRNA (see all 2): AIF1L
    OriGene siRNA (see all 2): AIF1L
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of AIF1L 
    miRNA: Sigma-Aldrich microRNA Mimics for AIF1L
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of AIF1L 
    6 SABiosciences Assays for microRNAs that regulate AIF1L:
    hsa-miR-1233 hsa-miR-1321 hsa-miR-124 hsa-miR-129-3p hsa-miR-506 hsa-miR-218
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: AIF1L
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: AIF1L
    OriGene untagged cDNA clones in CMV expression vector: AIF1L
    OriGene 3'-UTR Clone: AIF1L 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for AIF1L 
    Primers: OriGene genome-wide validated SYBR primer pairs: AIF1L
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for AIF1L: PPH07282A

    REFSEQ mRNAs for AIF1L gene (3 alternative transcripts): 

    NM_001185095.1  NM_001185096.1  NM_031426.3  

    Additional cDNA sequence: 

    AK022845.1 AK027181.1 AK057789.1 AK091912.1 AK128526.1 AK300473.1 AK314600.1 AL136566.1 
    AL833896.1 AY359067.1 BC009826.2 BC021253.2 CR601218.1 

    18 DOTS entries:

    DT.447855  DT.99994868  DT.92017556  DT.100027260  DT.99982473  DT.100792729  DT.121188365  DT.91817513 
    DT.95141278  DT.121188297  DT.40200881  DT.92015681  DT.100695306  DT.100792728  DT.121188305  DT.121188316 
    DT.121188320  DT.100724856 

    24/272 AceView cDNA sequences (see all 272):

    BP361202 Z45215 T12552 BF589149 BP362284 AA349627 CR601218 BP375194 
    CD559010 T12612 AA349673 BP348419 CD633153 BP348584 AA359971 AW169332 
    AI885408 NM_001002260 CD514425 Z40943 CB265746 T31713 F04100 BP338824 

    Unigene Cluster for AIF1L:

    Allograft inflammatory factor 1-like
    Hs.4944  [show with all ESTs]
    Unigene Representative Sequence: NM_001185095


    GeneLoc Exon Structure

    5/13 Alternative Splicing Database (ASD) splice patterns (SP) for AIF1L (see all 13)

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b · 7c ^ 8a · 8b · 8c ^ 9a · 9b · 9c ^ 10a · 10b · 10c ^ 11
    SP1:                    -           -     -                 -     -           -     -     -     -                                                               
    SP2:                    -           -     -     -     -     -     -           -     -     -     -                                                               
    SP3:                    -           -     -     -     -     -     -           -     -     -     -                             -     -     -     -     -         
    SP4:                    -           -     -     -     -     -     -           -     -     -     -                             -     -                           
    SP5:                    -           -     -     -     -     -     -           -     -     -     -           -     -                                             

    About this scheme

    ECgene alternative splicing isoforms for AIF1L
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000372301 ENST00000372314(uc004cac.1) ENST00000372298 ENST00000372302
    ENST00000372297 ENST00000372319 ENST00000372312 ENST00000478257 ENST00000372309(uc004cab.1 uc004cad.1 uc004cae.1 uc011mce.1)
    ENST00000472942 ENST00000372300 ENST00000247291

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    AIF1L expression in normal and diseased human tissues

    1  / 2

    6 probe-sets matching AIF1L gene

    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    52986_at2 U95-B 1 0.94 1.00 0.99 1.25 -- -- -- -- --
    44606_at2 U95-B 1 0.94 1.00 0.99 0.75 -- -- -- -- --
    223075_s_at2 U133-B 1 1.00 1.00 -- -- -- -- -- -- --
    223074_s_at2 U133-B 1 0.91 1.00 -- -- -- -- -- -- --
    223075_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    223074_s_at2 U133Plus2 1 0.91 1.00 -- -- -- -- -- -- --
    About this table

    AIF1L for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    AIF1L gene expression
    AIF1L gene electronic northern expression
    AIF1L gene sage expression
    About these images

    CGAP SAGE TAG: GGAGTGTGCG

    SOURCE GeneReport for Unigene cluster: Hs.4944
    Primers: OriGene genome-wide validated SYBR primer pairs: AIF1L
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for AIF1L: PPH07282A
        SABiosciences Custom PCR Arrays for AIF1L 


    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section

    Orthologs for AIF1L gene from 5/8 species (see all 8)
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    AIF1L1   -- allograft inflammatory factor 1-like 94.96(n)
    99.16(a)
    608545  XM_845597.1  XP_850690.1 
    cow
    (Bos taurus)
    AIF1L1   -- allograft inflammatory factor 1-like 91.88(n)
    98.32(a)
    617493  XM_001252568.1  XP_001252569.1 
    rat
    (Rattus norvegicus)
    RGD13050811   -- similar to ionized calcium binding adapter molecule 2 (Iba2) less 91.33(n)
    96(a)
    362107  XM_342410.3  XP_342411.3 
    mouse
    (Mus musculus)
    Aif1l1 , 5 2 (21.95 cM)5
    allograft inflammatory factor 1-like1, 5 92(n)1
    96(a)1
    1088971  NM_145144.11  NP_660126.11 
     AB0353225  AI0431245  (see all 15)
    chicken
    (Gallus gallus)
    C9orf581   -- chromosome 9 open reading frame 58 78.77(n)
    82.96(a)
    417179  XM_415461.2  XP_415461.1 
    About this table        Species with no ortholog for AIF1L

    ENSEMBL Gene Tree for AIF1L (if available)

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
    Paralogs for AIF1L gene
    AIF12  

    AIF1L for paralogs           About GeneDecksing



    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/338 NCBI SNPs in AIF1L are shown (see all 338)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 9 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ----------
    rs1847861,2
    C,H133994641(-) cgaagT/Cgctgg 2 -- int17Minor allele frequency- C:0.14NA WA 14
    rs3535091,2
    C,F,H,133997961(-) GTAGTC/GAAGGA 3 -- ut31 ese312Minor allele frequency- G:0.04MN NA WA 390
    rs3535101,2
    C,F,A,133996503(-) CAGTAT/ACCTCC 3 -- ut31 ese314Minor allele frequency- A:0.39NA NS EA WA 2116
    rs3535111,2
    C,A,133996460(-) CCCCCA/C/GAAACC 3 -- ut317NA WA 132
    rs3535121,2
    C,F,A,133996184(-) CTGGAA/GCCATG 3 -- ut31 ese317Minor allele frequency- G:0.40NS EA NA WA 2550
    rs3535131,2
    C,F,A,H,133995959(-) TTGATA/GTCAGC 3 -- ut31 ese314Minor allele frequency- G:0.40NS EA NA WA 2134
    rs3535141,2
    C,F,A,133995353(-) ggtacA/Gactcc 2 -- int112Minor allele frequency- G:0.41NS EA NA WA 638
    rs3535151,2
    C,F,A,133995282(-) CAGGCT/CGGGCC 2 -- int110Minor allele frequency- C:0.43NS EA NA WA 476
    rs3535161,2
    C,H133994691(-) aggctG/Agtctc 2 -- int17Minor allele frequency- A:0.14NA WA 14
    rs3535171,2
    C,A,H,133994370(-) aggtaT/Acttgc 2 -- int110Minor allele frequency- A:0.23NA EA WA 224
    About this table

    HapMap Linkage Disequilibrium images for AIF1L (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for AIF1L
         1 CNV: 3782

    QIAGEN SeqTarget long-range PCR primers for resequencing AIF1L 

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    AIF1L for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: AIF1L (1 document)

    Export disorders and mutations for AIF1L gene to outside databases

    (Possibly Related Articles in Doctor's Guide)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/15 PubMed articles for AIF1L gene, integrated from 7 sources (see all 15):
    (articles sorted by number of sources associating them with AIF1L)
    1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (2001)
    2. Structural and functional characterization of human Iba proteins. (PubMed id 18699778)1, 2, 7 Schulze J.O....Bussow K. (2008)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
    6. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    7. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (2010)
    8. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    9. The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (2006)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 83543 HGNC: 28904 AceView: C9orf58 Ensembl:ENSG00000126878 euGenes: HUgn83543
    ECgene: AIF1L H-InvDB: AIF1L

    (According to HUGE)
    About This Section
      --

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
      --

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
    About This Section
    Patent Information for AIF1L gene:
    Search GeneIP for patents involving AIF1L

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
    Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
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     Browse ELISAs and CLIAs at Uscn
           

    GeneCards Homepage - Last full update: 30 Dec 2010 - Incremental updates: 10 Jan 2011 , 10 Jan 2011

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