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ALKBH8 Gene

protein-coding   GIFtS: 45

GC11M103298
alkB, alkylation repair homolog 8 (E. coli)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
alkB, alkylation repair homolog 8 (E. coli)1 2     AlkB homologue 82
ABH82 3 5     FLJ382042
MGC102351 2     OTTHUMP000002112862
Probable alpha-ketoglutarate-dependent dioxygenase ABH82 3     OTTHUMP000002112872
S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH82 3     EC 2.1.1.-3
alkylated DNA repair protein alkB homolog 82     EC 1.14.11.-3

External Ids:    HGNC: 251891   Entrez Gene: 918012   Ensembl: ENSG000001377607   UniProtKB: Q96BT73   

Export aliases for ALKBH8 gene to outside databases

Previous GC identifers: GC11M106879 GC11M107373


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: ALKB8_HUMAN, Q96BT7
Function: Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position
of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble
position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind
tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and
angiogenesis


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ALKBH8 gene promoter:
         C/EBPalpha   CHOP-10   FOXD1   POU3F2   FOXJ2 (long isoform)   SREBP-1a   SREBP-1b   SREBP-1c   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for ALKBH8

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q22.3   Ensembl cytogenetic band:  11q22.3   HGNC cytogenetic band: 11q22.3

ALKBH8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ALKBH8 gene location

GeneLoc gene densities for chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M103298:  view genomic region     (about GC identifiers)

Start:
103,298,990 bp from pter
End:
103,361,859 bp from pter
Size:
62,870 bases
Orientation:
minus strand

1 alternative location:
Chr11- 107,373,452-107,436,461     
RefSeq DNA sequence:
NC_000011.9  NT_033899.8  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: ALKB8_HUMAN, Q96BT7 (See protein sequence)
Recommended Name: Alkylated DNA repair protein alkB homolog 8  
Size: 664 amino acids; 75208 Da
Subunit: Interacts with TRMT112
Subcellular location: Cytoplasm. Nucleus. Note=Predominantly cytoplasmic
PDB structures from and Proteopedia :
2CQ2 (3D)    
Secondary accessions: B1Q2M0 B4DEF6 Q8N989
Alternative splicing: 4 isoforms:  Q96BT7-1   Q96BT7-2   Q96BT7-3   Q96BT7-4   

Explore the universe of human proteins at neXtProt for ALKBH8: NX_Q96BT7 

REFSEQ proteins: NP_620130.2  

ENSEMBL proteins: 
ENSP00000410820 ENSP00000376812 ENSP00000374219 ENSP00000397673 ENSP00000260318 ENSP00000391225 
ENSP00000415885 


Human Recombinant Proteins 
Browse Purified and Recombinant Proteins at Millipore
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Browse recombinant and purified proteins available from Enzo Life Sciences
Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
Browse OriGene Protein Over-expression Lysates
GenScript Custom Purified and Recombinant Proteins Services for ALKBH8 
Novus Biologicals Protein for ALKBH8
Browse Sino Biological Recombinant Proteins
Browse ProSpec Recombinant Proteins

5 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005622 intracellular ----
GO:0005634 nucleus IDA--
GO:0005737 cytoplasm IEA--
GO:0005829 cytosol IDA--
GO:0005840 ribosome ----
About this table

ALKBH8 for ontologies           About GeneDecksing



Antibodies for ALKBH8: 
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Sigma-Aldrich Antibodies for ALKBH8
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GenScript Custom Superior Antibodies Services for ALKBH8 
Browse antibodies at Epitomics

Assays for ALKBH8: 
Browse Kits and Assays available from Millipore
Browse ELISAs at Sigma-Aldrich
OriGene Custom Immunoassay Development 
Browse OriGene Fluorogenic Cell Assay Kits 
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for ALKBH8 
Browse Enzo Life Sciences for kits & assays
Uscn ELISAs and CLIAs for ALKBH8 


(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ALKBH8 for domains           About GeneDecksing

4 InterPro domains/families:
 IPR012677 Nucleotide-bd_a/b_plait
 IPR013216 Methyltransf_11
 IPR005123 Oxoglutarate/Fe-dep_oxygenase
 IPR015095 AlkB_hom8_N

Graphical View of Domain Structure for InterPro Entry Q96BT7

ProtoNet protein and cluster: Q96BT7

2 Blocks protein families:
IPB000504 RNA-binding region RNP-1 (RNA recognition motif)
IPB001014 Ribosomal L23 protein


UniProtKB/Swiss-Prot: ALKB8_HUMAN, Q96BT7
Similarity: Belongs to the alkB family
Similarity: Contains 1 Fe2OG dioxygenase domain
Similarity: Contains 1 RRM (RNA recognition motif) domain


(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: ALKB8_HUMAN, Q96BT7
Function: Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position
of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble
position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind
tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and
angiogenesis
Induction: Up-regulated after DNA damage. Induction is mediated via ATM
Enzyme Numbers (IUBMB): EC 1.14.11.-  EC 2.1.1.- 

Inhib.
RNA:
    
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich esiRNA and siRNA for ALKBH8
Sigma-Aldrich shRNA for ALKBH8
OriGene 29mer shRNA kits in GFP-retroviral vector: ALKBH8
OriGene shRNA RFP: ALKBH8
OriGene basic RS shRNA: ALKBH8
OriGene siRNA: ALKBH8
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of ALKBH8 
miRNA:Sigma-Aldrich microRNA Mimics for ALKBH8
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of ALKBH8 
1 SABiosciences Assays for microRNA that regulate ALKBH8:
hsa-miR-432

Gene
Editing:
Browse CompoZr Knockout ZFN at Sigma-Aldrich 

Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
Browse iPSC Reprogramming Factors at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: ALKBH8
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: ALKBH8
OriGene untagged cDNA clones in CMV expression vector (see all 2): ALKBH8
OriGene 3'-UTR clone: ALKBH8 
Browse MicroRNA Expression Plasmids 
GenScript Custom cDNA clone Services for ALKBH8 
Browse Sino Biological Human cDNA Clones

Cell
Lines:
  
GenScript Custom overexpressing Cell Line Services for ALKBH8 

5/10 Gene Ontology (GO) molecular function terms (GO ID links to tree view) (see all 10):

GO IDQualified GO termEvidencePubMed IDs
GO:0000166 nucleotide binding IEA--
GO:0003676 nucleic acid binding ----
GO:0003723 RNA binding IEA--
GO:0003735 structural constituent of ribosome ----
GO:0005515 protein binding IPI--
About this table

ALKBH8 for ontologies           About GeneDecksing

Animal Models: 1 MGI mutant phenotype (inferred from 1 allele(MGI details for Alkbh8):

normal

ALKBH8 for phenotypes           About GeneDecksing


(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section

    SABiosciences Custom Pathway-Focused PCR Arrays for ALKBH8 

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ALKBH8

5 Gene Ontology (GO) biological process terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0006412 translation ----
GO:0006974 response to DNA damage stimulus IDA--
GO:0008152 metabolic process ----
GO:0030488 tRNA methylation IDA--
GO:0055114 oxidation-reduction process IEA--
About this table

ALKBH8 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section
Browse Small Molecules at Sigma-Aldrich
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ALKBH8


(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib.
RNA:
     
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich esiRNA and siRNA for ALKBH8
Sigma-Aldrich shRNA for ALKBH8
OriGene 29mer shRNA kits in GFP-retroviral vector: ALKBH8
OriGene shRNA RFP: ALKBH8
OriGene basic RS shRNA: ALKBH8
OriGene siRNA: ALKBH8
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of ALKBH8 
miRNA: Sigma-Aldrich microRNA Mimics for ALKBH8
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of ALKBH8 
1 SABiosciences Assays for microRNA that regulate ALKBH8:
hsa-miR-432
Clones: Browse FLAG tag genes at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: ALKBH8
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: ALKBH8
OriGene untagged cDNA clones in CMV expression vector (see all 2): ALKBH8
OriGene 3'-UTR Clone: ALKBH8 
Browse OriGene MicroRNA Expression Plasmids 
GenScript Custom cDNA clone Services for ALKBH8 
Primers: OriGene genome-wide validated SYBR primer pairs: ALKBH8
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for ALKBH8: PPH10472A

REFSEQ mRNAs for ALKBH8 gene: 

NM_138775.2  

Additional cDNA sequence: 

AB218768.1 AF086489.1 AK095523.1 AK293603.1 AK298800.1 AK304413.1 BC015183.1 BX649085.1 

5 DOTS entries:

DT.100016636  DT.108954  DT.40305950  DT.108955  DT.120738863 

24/51 AceView cDNA sequences (see all 51):

BM054901 CK904381 AA411920 AA393087 BC015183 BX109798 AA313350 AA262405 
BG574178 AA806370 BM753257 BQ010516 AF086489 NM_138775 BM054706 BX956410 
AI925740 AA337166 BE887937 CD172200 CB958294 BG573506 CA444499 BX472466 

highest scoring ESTs for ALKBH8:

AA313350 AI925740 BC015183 BE887937 BG255644 AA336257 AA337166 AA411920 AF086489 AI590659 

Unigene Cluster for ALKBH8:

AlkB, alkylation repair homolog 8 (E. coli)
Hs.503763  [show with all ESTs]
Unigene Representative Sequence: NM_138775


GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for ALKBH8

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b
SP1:                                                                          -     -               
SP2:                                                                                                
SP3:                                                                                                
SP4:              -                                                                                 

About this scheme

ECgene alternative splicing isoforms for ALKBH8
7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000449781(uc001pjl.2) ENST00000393100 ENST00000389568 ENST00000417449(uc009yxp.2)
ENST00000260318 ENST00000429370 ENST00000428149(uc001pjk.2 uc010rvq.1 uc010rvr.1)


(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

ALKBH8 expression in normal and diseased human tissues

1  / 2  / 3

6 probe-sets matching ALKBH8 gene

Affymetrix
probe-set
Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
87116_at2, 3 U95-E 2 1.00 0.97 0.81 0.97 AI925740 0.80 1.00 0.91 1
54389_at2, 3 U95-C 1 0.81 1.00 0.95 1.03 AI590659 0.60 1.00 0.82 1
235713_at2, 3 U133-B 1 1.00 1.00 -- -- BF242537 0.40 1.00 0.76 1
235610_at2, 3 U133-B 1 0.91 1.00 -- -- AI590659 0.60 1.00 0.82 1
235713_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
235610_at2 U133Plus2 1 0.91 1.00 -- -- -- -- -- -- --
About this table

ALKBH8 for expression           About GeneDecksing

Data from Genenote  (Publications) and GNF BioGPS
    About these images
ALKBH8 gene expression
ALKBH8 gene electronic northern expression
ALKBH8 gene sage expression
About these images

CGAP SAGE TAG: CCAATAAATT

SOURCE GeneReport for Unigene cluster: Hs.503763

UniProtKB/Swiss-Prot: ALKB8_HUMAN, Q96BT7
Tissue specificity: Widely expressed, with highest expression in spleen, followed by pancreas and lung

Primers: OriGene genome-wide validated SYBR primer pairs: ALKBH8
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for ALKBH8: PPH10472A
    SABiosciences Custom PCR Arrays for ALKBH8 


(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ALKBH8 gene from 5/16 species (see all 16)
Organism Gene Locus Description Human
Similarity
NCBI accessions
dog
(Canis familiaris)
ALKBH81   -- alkB, alkylation repair homolog 8 (E. coli) 89.8(n)
87.93(a)
489424  XM_546542.2  XP_546542.2 
chimpanzee
(Pan troglodytes)
ALKBH81   -- alkB, alkylation repair homolog 8 (E. coli) 99.28(n)
98.28(a)
466772  XM_001137322.1  XP_001137322.1 
rat
(Rattus norvegicus)
Alkbh81   -- alkB, alkylation repair homolog 8 (E. coli) 82.47(n)
77.16(a)
366783  XM_345766.3  XP_345767.3 
mouse
(Mus musculus)
Alkbh81 , 5 9 (2.02 cM)5
alkB, alkylation repair homolog 8 (E. coli)1, 5 81.9(n)1
76.29(a)1
676671  NM_026303.11  NP_080579.11 
 AA7561315  AK0161885  (see all 20)
chicken
(Gallus gallus)
ALKBH81   -- alkB, alkylation repair homolog 8 (E. coli) 71.59(n)
63.48(a)
418972  XM_417166.2  XP_417166.2 
About this table        Species with no ortholog for ALKBH8

ENSEMBL Gene Tree for ALKBH8 (if available)

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
Paralogs for ALKBH8 gene
ENSG000002503052  

ALKBH8 for paralogs           About GeneDecksing



(SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

10/670 NCBI SNPs in ALKBH8 are shown (see all 670)
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidChr 11 posSequenceRecsAA
Chg
TypeMoreRecsAllele
freq
PopTotal
sample
More
----------
rs4716681,2
C,F,A,H,107415947(+) GTGGTT/ATAAAG 1 -- int113Minor allele frequency- A:0.32NA EA WA 366
rs4755741,2
107429897(+) cacgaC/Ttgtga 1 -- int10--------
rs4772061,2
C,F,A,H,107387656(-) cctccT/Cacctc 1 -- int17Minor allele frequency- C:0.39NA WA 18
rs4773901,2
C,A107387726(+) gcctgA/Ggcaac 1 -- int16Minor allele frequency- G:0.33NA WA 12
rs4784041,2
H107430244(+) TTTCTT/GGCTAC 1 -- int1 trp35Minor allele frequency- G:0.00MN NS EA 570
rs4786251,2
C,F,107402219(+) gagaaA/Tctctt 1 -- int15Minor allele frequency- T:0.05NS EA WA 458
rs4791931,2
C,F,O,A,107430300(+) GAAAGA/C/TGATGA 1 -- int17MN NS NA EA WA 470
rs4841781,2
C,A,107413574(+) gaggcT/Cgcagt 1 -- int16Minor allele frequency- C:0.17NA WA 12
rs4870861,2
--107390200(+) GAAAAC/TCAGAC 1 -- int10--------
rs4871011,2
--107413909(+) aatacA/Caaaat 1 -- int11Minor allele frequency- C:0.00MN 184
About this table

HapMap Linkage Disequilibrium images for ALKBH8 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for ALKBH8: --

QIAGEN SeqTarget long-range PCR primers for resequencing ALKBH8 

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ALKBH8 for disorders           About GeneDecksing

OMIM: 613306


Export disorders and mutations for ALKBH8 gene to outside databases

(Possibly Related Articles in Doctor's Guide)
About This Section
  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
About This Section

8 PubMed articles for ALKBH8 gene integrated from 7 sources:
(articles sorted by number of sources associating them with ALKBH8)
  1. A novel human AlkB homologue, ALKBH8, contributes to human bladder cancer progression. (PubMed id 19293182)1, 2, 7 Shimada K.... Konishi N. (2009)
  2. Human AlkB homolog ABH8 is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival. (PubMed id 20308323)1, 2 Fu D.... Samson L.D. (2010)
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
  5. Expression and sub-cellular localization of human ABH family molecules. (PubMed id 17979886)2 Tsujikawa K....Yamamoto H. (2007)
  6. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
  7. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)
  8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 91801 HGNC: 25189 AceView: LOC91801 Ensembl:ENSG00000137760 euGenes: HUgn91801
ECgene: ALKBH8 H-InvDB: ALKBH8

(According to HUGE)
About This Section
  --

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
  --

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from XenneX, Inc.)
About This Section
Patent Information for ALKBH8 gene:
Search GeneIP for patents involving ALKBH8

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
About This Section

 Millipore Custom Antibody & Bulk Services
 Millipore Preclinical / Clinical Development Services
 Millipore Immunoassay Services
 Millipore Target Screening & Profiling Services

 Predesigned and custom siRNAs for ALKBH8 Antibodies for ALKBH8
 Super-pooled esiRNAs for ALKBH8 Browse proteins at Sigma-Aldrich
 Lentivirus-delivered shRNAs for ALKBH8 microRNA Mimics for ALKBH8
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