ARMCX4 Gene
RNA gene GIFtS: 37
GC0XP090479
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armadillo repeat containing, X-linked 4
(Previous names: chromosome X open reading frame 35, armadillo repeat containing, X-linked 4 pseudogene )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: CXorf35)
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Aliases &
Descriptions
for ARMCX4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
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| Aliases & Descriptions |
|---|
| armadillo repeat containing, X-linked 41 2 | | DKFZp586N08192 | | MGC400531 2 | | FLJ396362 | | armadillo repeat containing, X-linked 4 pseudogene1 | | FLJ450412 | | chromosome X open reading frame 351 | | CXorf352 | | FLJ430512 | | DKFZp781M04152 |
Export aliases for ARMCX4 gene to outside databasesPrevious GC identifers: GC0XP100546 GC0XP100627 GC0XU901218 GC0XP100561 GC0XP100673 |
Summaries
for ARMCX4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
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-- |
Genomic Views
for ARMCX4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
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Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ARMCX4 gene promoter:
oct-B3 POU2F2 oct-B2 POU2F2 (Oct-2.1) POU2F2C POU2F2B Oct-B1 POU2F1 Arnt Elk-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ARMCX4
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for ARMCX4  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq22.1 Ensembl cytogenetic band: Xq22.1 HGNC cytogenetic band: Xq22ARMCX4 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP090479: view genomic region
(about GC identifiers)
Start:
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90,479,154 bp from pter |
End:
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90,596,521 bp from pter |
Size:
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117,368 bases |
Orientation:
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plus strand |
1 alternative location:
| ChrX+ 100,673,275-100,788,446 |
RefSeq DNA sequence:- NC_000023.10 NT_011651.17
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Proteins
for ARMCX4 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
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UniProtKB/Swiss-Prot: ARMX4_HUMAN, Q5H9R4 (See
protein sequence)Recommended Name: Armadillo repeat-containing X-linked protein 4 Size: 360 amino acids; 39406 Da
Subcellular location: Membrane; Single-pass membrane protein (Potential)
Secondary accessions: A8K928 B3KXA4 Q5H9K8 Q8N8D6Alternative splicing: 2 isoforms: Q5H9R4-1 Q5H9R4-2 Explore the universe of human proteins at neXtProt for ARMCX4: NX_Q5H9R4
ENSEMBL proteins: ENSP00000423927 ENSP00000404304 ENSP00000422573 ENSP00000424452 ENSP00000426585 ENSP00000423440 ENSP00000425302
Human Recombinant Proteins
2 Gene Ontology (GO) cellular component terms (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016020 | membrane |
IEA | -- | | GO:0016021 | integral to membrane |
IEA | -- |
About this table
ARMCX4 for ontologies About GeneDecksing
Antibodies for ARMCX4:
Assays for ARMCX4: |
Protein
Domains/
Families
for ARMCX4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q5H9R4 |
Gene Function
for ARMCX4 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
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1 Gene Ontology (GO) molecular function term (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005488 | binding |
-- | -- |
About this table
ARMCX4 for ontologies About GeneDecksing
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Pathways & Interactions
for ARMCX4 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
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SABiosciences Custom Pathway-Focused PCR Arrays for ARMCX4
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ARMCX4
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Drugs & Compounds
for ARMCX4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
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 Browse Tocris compounds for ARMCX4
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Transcripts
for ARMCX4 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
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Additional cDNA sequence: AB039670.1 AF248963.1 AK074785.1 AK096955.1 AK125041.1 AK126987.1 AK222578.1 AK292543.1 AL050285.1 AY726601.1 BC002691.2 BC032236.1 BC036206.1 CR595436.1 CR616090.1 CR749609.1 CR933662.1 23 DOTS entries: DT.413312 DT.211474 DT.95361872 DT.100812315 DT.95255657 DT.100653257 DT.91679582 DT.121279997 DT.121280005 DT.40249069 DT.70104777 DT.91749742 DT.100648462 DT.101982813 DT.121297393 DT.75123992 DT.95265219 DT.100747808 DT.102829343 DT.121280044 DT.121280046 DT.121280048 DT.121309545
 highest scoring ESTs for ARMCX4:AK096955 AK126987 BC032236 BC036206 AI223992 AK125041 BI915421 BI918288 BP377098 BX411274 Unigene Cluster for ARMCX4: Armadillo repeat containing, X-linked 4 Hs.9728 [show with all ESTs]Unigene Representative Sequence: CR933662
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for ARMCX4 (see all 9)
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8a | · | 8b | · | 8c | ^ | 9a | · | 9b | ^ | 10a | · | 10b |
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| SP1: | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | - | | | | - | | - | | - | | - | | | | | | - | | - | | - | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | - | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for ARMCX4
10 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000354842 ENST00000423738 ENST00000445416(uc004ehq.2) ENST00000453574
ENST00000433011(uc004ehu.1 uc004eho.1) ENST00000442270(uc004eht.2)
ENST00000455331 ENST00000430461 ENST00000452188(uc004ehp.2 uc004ehr.2 uc004ehs.2)
ENST00000431677
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Expression
for ARMCX4 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| ARMCX4 expression in normal and diseased human tissues
1 / 2 / 3 1 probe-set matching ARMCX4 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 62542_at2, 3
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U95-C |
1 |
0.44 |
1.00 |
1.00 |
1.00 |
AW008597 |
0.20 |
1.00 |
0.72 |
1 |
About this table
ARMCX4 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: CATAAGCTAC
SOURCE GeneReport for Unigene cluster: Hs.9728
Expression variation in blood from EXPOLDB for ARMCX4 SABiosciences Custom PCR Arrays for ARMCX4
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Orthologs
for ARMCX4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
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Orthologs for ARMCX4 gene from 1 species
| Organism |
Gene |
Locus |
Description |
Human
Similarity |
NCBI accessions |
mouse
(Mus musculus) |
Armcx45 |
X (56.23 cM) |
armadillo repeat containing, X-linked 4 |
-- |
BG081460 |
About this table Species with no ortholog for ARMCX4
ENSEMBL Gene Tree for ARMCX4 (if available) |
Paralogs
for ARMCX4 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for ARMCX4 gene
- GPRASP22 ARMCX12 BHLHB92 ARMCX22 ARMCX52 GPRASP12 ARMCX62 ARMC102
- ARMCX32
ARMCX4 for paralogs About GeneDecksing
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Genomic Variants
for ARMCX4 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr X pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for ARMCX4 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for ARMCX4
3 CNVs: 96855 96856 83653
3 Indels: 83652 96854 103267 | | QIAGEN SeqTarget long-range PCR primers for resequencing ARMCX4 |
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Disorders & Mutations
for ARMCX4 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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Medical News
for ARMCX4 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
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Publications
for ARMCX4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
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6 PubMed articles for ARMCX4 gene integrated from 7 sources:
(articles sorted by number of sources associating them with ARMCX4)- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)1, 2 Bechtel S.... Schupp I. (2007)
- The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The sequence of the human genome. (PubMed id 11181995)1 Venter J.C.... Zhu X. (2001)
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External Searches for ARMCX4 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing ARMCX4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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Other Databases showing ARMCX4 gene
(According to HUGE)
About This Section
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Specialized Databases showing ARMCX4 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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About This Section
| Patent Information for ARMCX4 gene:
Search GeneIP for patents involving ARMCX4
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ARMCX4 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
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