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AWAT2 Gene

protein-coding   GIFtS: 42

GC0XM063081
acyl-CoA wax alcohol acyltransferase 2
(Previous name: diacylglycerol O-acyltransferase 2-like 4 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: DGAT2L4)
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
acyl-CoA wax alcohol acyltransferase 21 2     DC42 3
MFAT1 2 3     diacylglycerol O-acyltransferase 2-like 41
Diacylglycerol O-acyltransferase 2-like protein 42 3     OTTHUMP000002172802
Multifunctional O-acyltransferase2 3     Wax synthase3
Diacylglycerol O-acyltransferase candidate 42 3     hDC43
Long-chain-alcohol O-fatty-acyltransferase 22 3     hWS3
DGAT2L42 3     EC 2.3.1.753
WS2 3     

External Ids:    HGNC: 232511   Entrez Gene: 1588352   Ensembl: ENSG000001471607   UniProtKB: Q6E2133   

Export aliases for AWAT2 gene to outside databases

Previous GC identifer: GC0XM069178


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for AWAT2:
This gene encodes an enzyme belonging to the diacylglycerol acyltransferase family. This enzyme produces wax esters by
the esterification of long chain (or wax) alcohols with acyl-CoA-derived fatty acids. It functions in lipid metabolism
in the skin, mostly in undifferentiated peripheral sebocytes. This enzyme may also have acyl-CoA:retinol
acyltransferase activities, where it catalyzes the synthesis of diacylglycerols and retinyl esters. (provided by
RefSeq)

UniProtKB/Swiss-Prot: AWAT2_HUMAN, Q6E213
Function: Acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to
produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in
skin. Has no activity using decyl alcohol and significantly prefers the C16 and C18 alcohols. May also have
2-acylglycerol O-acyltransferase (MGAT) and acyl-CoA:retinol acyltransferase (ARAT) activities, to catalyze the
synthesis of diacylglycerols and retinyl esters; however this activity is unclear in vivo


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for AWAT2
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for AWAT2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq13.1   Ensembl cytogenetic band:  Xq13.1   HGNC cytogenetic band: Xq13.1

AWAT2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AWAT2 gene location

GeneLoc gene densities for chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM063081:  view genomic region     (about GC identifiers)

Start:
63,081,194 bp from pter
End:
63,090,585 bp from pter
Size:
9,392 bases
Orientation:
minus strand

1 alternative location:
ChrX- 69,260,392-69,269,788     
RefSeq DNA sequence:
NC_000023.10  NT_011669.17  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: AWAT2_HUMAN, Q6E213 (See protein sequence)
Recommended Name: Acyl-CoA wax alcohol acyltransferase 2  
Size: 333 amino acids; 38094 Da
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein
Secondary accessions: Q6IEE3 Q6P437

Explore the universe of human proteins at neXtProt for AWAT2: NX_Q6E213 

REFSEQ proteins: NP_001002254.1  

ENSEMBL proteins: 
ENSP00000421172 ENSP00000427523 


Human Recombinant Proteins 
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OriGene Protein Over-expression Lysate: AWAT2
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4 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005783 endoplasmic reticulum IEA--
GO:0005789 endoplasmic reticulum membrane IEA--
GO:0016020 membrane IEA--
GO:0016021 integral to membrane IEA--
About this table

AWAT2 for ontologies           About GeneDecksing



Antibodies for AWAT2: 
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Uscn ELISAs and CLIAs for AWAT2 


(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

AWAT2 for domains           About GeneDecksing

1 InterPro domain/family:
 IPR007130 DAGAT

Graphical View of Domain Structure for InterPro Entry Q6E213

ProtoNet protein and cluster: Q6E213

UniProtKB/Swiss-Prot: AWAT2_HUMAN, Q6E213
Similarity: Belongs to the diacylglycerol acyltransferase family


(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: AWAT2_HUMAN, Q6E213
Function: Acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to
produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in
skin. Has no activity using decyl alcohol and significantly prefers the C16 and C18 alcohols. May also have
2-acylglycerol O-acyltransferase (MGAT) and acyl-CoA:retinol acyltransferase (ARAT) activities, to catalyze the
synthesis of diacylglycerols and retinyl esters; however this activity is unclear in vivo
Catalytic activity: Acyl-CoA + a long-chain alcohol = CoA + a long-chain ester
Biophysicochemical properties: Kinetic parameters: Vmax=1232 pmol/min/mg enzyme with [14C]cetyl-CoA as substrate;
Enzyme Number (IUBMB): EC 2.3.1.75 

Inhib.
RNA:
    
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich siRNA for AWAT2
Sigma-Aldrich shRNA for AWAT2
OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): AWAT2
OriGene shRNA RFP (see all 2): AWAT2
OriGene basic RS shRNA (see all 2): AWAT2
OriGene siRNA (see all 2): AWAT2
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of AWAT2 
miRNA:Sigma-Aldrich microRNA Mimics for AWAT2
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of AWAT2 
1 SABiosciences Assays for microRNA that regulate AWAT2:
hsa-miR-361-5p

Gene
Editing:
Browse CompoZr Knockout ZFN at Sigma-Aldrich 

Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
Browse iPSC Reprogramming Factors at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: AWAT2
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: AWAT2
OriGene untagged cDNA clones in CMV expression vector: AWAT2
Browse 3'-UTR reporter clones for miRNA target validation 
Browse MicroRNA Expression Plasmids 
GenScript cDNA clone with any tag delivered in your preferred vector: AWAT2 
Browse Sino Biological Human cDNA Clones

Cell
Lines:
  
GenScript Custom overexpressing Cell Line Services for AWAT2 

4 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0008415 acyltransferase activity IEA--
GO:0016740 transferase activity IEA--
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups ----
GO:0047196 long-chain-alcohol O-fatty-acyltransferase activity IEA--
About this table

AWAT2 for ontologies           About GeneDecksing


(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section


AWAT2 for pathways           About GeneDecksing

1 Kegg Pathway  (Kegg details for AWAT2):
    hsa00830 Retinol metabolism

    SABiosciences Custom Pathway-Focused PCR Arrays for AWAT2 

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AWAT2

2 Gene Ontology (GO) biological process terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0008610 lipid biosynthetic process IEA--
GO:0010025 wax biosynthetic process IEA--
About this table

AWAT2 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section
Browse Small Molecules at Sigma-Aldrich
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for AWAT2


(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib.
RNA:
     
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich siRNA for AWAT2
Sigma-Aldrich shRNA for AWAT2
OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): AWAT2
OriGene shRNA RFP (see all 2): AWAT2
OriGene basic RS shRNA (see all 2): AWAT2
OriGene siRNA (see all 2): AWAT2
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of AWAT2 
miRNA: Sigma-Aldrich microRNA Mimics for AWAT2
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of AWAT2 
1 SABiosciences Assays for microRNA that regulate AWAT2:
hsa-miR-361-5p
Clones: Browse FLAG tag genes at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: AWAT2
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: AWAT2
OriGene untagged cDNA clones in CMV expression vector: AWAT2
Browse 3'-UTR reporter clones for miRNA target validation 
Browse OriGene MicroRNA Expression Plasmids 
GenScript cDNA clone with any tag delivered in your preferred vector: AWAT2 
Primers: OriGene genome-wide validated SYBR primer pairs: AWAT2
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for AWAT2: PPH13999A

REFSEQ mRNAs for AWAT2 gene: 

NM_001002254.1  

Additional cDNA sequence: 

AY605053.1 BC063698.1 

2 DOTS entries:

DT.406619  DT.95358368 

14 AceView cDNA sequences:

BX096548 BG743254 BC063698 AA629135 NM_001002254 AY605053 BG740651 BX110378 
AA252887 BG742848 BG743236 AA253425 BG674003 AA969335 

Unigene Cluster for AWAT2:

Acyl-CoA wax alcohol acyltransferase 2
Hs.661507  [show with all ESTs]
Unigene Representative Sequence: NM_001002254


GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for AWAT2

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b · 5c ^ 6a · 6b · 6c ^ 7a · 7b
SP1:                                      -     -     -                                       
SP2:                                      -                                                   
SP3:                                      -     -     -                                       
SP4:                                                                                          
SP5:                                                                                          

About this scheme

ECgene alternative splicing isoforms for AWAT2
3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000276101(uc004dxt.1) ENST00000443056 ENST00000440401

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

AWAT2 expression in normal and diseased human tissues

1  / 2

1 probe-set matching AWAT2 gene

Affymetrix
probe-set
Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
68168_at2 U95-E 1 0.50 1.00 1.00 1.00 -- -- -- -- --
About this table

AWAT2 for expression           About GeneDecksing

Data from Genenote  (Publications) and GNF BioGPS
    About these images
AWAT2 gene expression
AWAT2 gene electronic northern expression
AWAT2 gene sage expression
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.661507

UniProtKB/Swiss-Prot: AWAT2_HUMAN, Q6E213
Tissue specificity: Abundant in tissues rich in sebaceous glands such as the preputial gland and eyelid. Highly
expressed in skin, where it is primarily restricted to undifferentiated peripheral sebocytes. Also expressed at lower
level in other tissues except pancreas

Primers: OriGene genome-wide validated SYBR primer pairs: AWAT2
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for AWAT2: PPH13999A
    SABiosciences Custom PCR Arrays for AWAT2 


(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for AWAT2 gene from 5 species
Organism Gene Locus Description Human
Similarity
NCBI accessions
dog
(Canis familiaris)
DGAT2L41   -- diacylglycerol O-acyltransferase 2-like 4 86.69(n)
84.38(a)
491936  XM_549056.2  XP_549056.2 
chimpanzee
(Pan troglodytes)
DGAT2L41   -- diacylglycerol O-acyltransferase 2-like 4 99.9(n)
99.7(a)
473654  XM_529027.2  XP_529027.1 
cow
(Bos taurus)
DGAT2L41   -- diacylglycerol O-acyltransferase 2-like 4 84.7(n)
80.66(a)
521298  XM_599558.3  XP_599558.3 
rat
(Rattus norvegicus)
Dgat2l41   -- diacylglycerol O-acyltransferase 2-like 4 84.38(n)
80.78(a)
302425  XM_228583.4  XP_228583.4 
mouse
(Mus musculus)
Awat25
Dgat2l41
X (43.71 cM)5
acyl-CoA wax alcohol acyltransferase 25
diacylglycerol O-acyltransferase 2-like 41
85.99(n)1
84.38(a)1
2455321  NM_177746.31  NP_808414.21 
 AK0349205  AY6110315  (see all 8)
About this table        Species with no ortholog for AWAT2

ENSEMBL Gene Tree for AWAT2 (if available)

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
Paralogs for AWAT2 gene
MOGAT32  DGAT2L72  DGAT22  MOGAT12  DGAT2L62  MOGAT22  AWAT12  

AWAT2 for paralogs           About GeneDecksing



(SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

10/54 NCBI SNPs in AWAT2 are shown (see all 54)
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidChr X posSequenceRecsAA
Chg
TypeMoreRecsAllele
freq
PopTotal
sample
More
----------
rs14099931,2
C,F,O,A,69266212(+) TCACTA/GTGAAA 1 -- int120Minor allele frequency- T:0.04NS EA NA 1128
rs14099941,2
C,F,A,69269239(+) TAAATG/TGTCGA 1 -- int118Minor allele frequency- T:0.08NA EA MN NS WA 1182
rs14099951,2
C,F,A,69269295(+) CAACTG/ATCTCT 1 -- int114Minor allele frequency- A:0.10NS EA NA WA 743
rs22819321,2
C,F,O,A,H,69260936(+) TATTTC/TGGGCG 1 -- ut31 ese323Minor allele frequency- T:0.23NS EA NA 1637
rs22819331,2
C,F,A,69261818(+) CTGCCA/GGGGGA 1 -- int17Minor allele frequency- G:0.40NS EA NA 422
rs22967671,2
C,F,69262423(+) CAAAGC/TAGCAG 1 -- int19Minor allele frequency- T:0.13NS EA NA WA 424
rs22967681,2
C,F69262450(+) GCAAGC/TCCAGA 1 -- int15Minor allele frequency- T:0.12NS EA NA 419
rs23829661,2
C,69266864(-) cctcaC/Ttttat 1 -- int11Minor allele frequency- T:0.00NA 2
rs32158441,2
--69262738(+) ttttt-/TTaactt 1 -- int10--------
rs59368261,2
C69260363(+) GTTTTT/GTAAGG 1 -- ng314Minor allele frequency- G:0.00NS EA 412
About this table

HapMap Linkage Disequilibrium images for AWAT2 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for AWAT2: --

Search QIAGEN SeqTarget long-range PCR primers for resequencing for AWAT2 

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section
  --

(Possibly Related Articles in Doctor's Guide)
About This Section
  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
About This Section

7 PubMed articles for AWAT2 gene integrated from 7 sources:
(articles sorted by number of sources associating them with AWAT2)
  1. Identification of two novel human Acyl-CoA wax alcohol acyltransferases: members of the diacylglycerol acyltransferase 2 (DGAT2) gene superfamily. (PubMed id 15671038)1, 2, 3 Turkish A.R.... Sturley S.L. (2005)
  2. A human skin multifunctional O-acyltransferase that catalyzes the synthesis of acylglycerols, waxes, and retinyl esters. (PubMed id 16106050)1, 2, 3 Yen C.-L.E.... Farese R.V. Jr. (2005)
  3. Genomic organization of the DGAT2/MOGAT gene family in cattle (Bos taurus) and other mammals. (PubMed id 14970677)1, 2, 3 Winter A....Fries R. (2003)
  4. Mammalian wax biosynthesis. II. Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family. (PubMed id 15220349)1, 2 Cheng J.B. and Russell D.W. (2004)
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  6. Comparative genomics and proteomics of vertebrate dia cylglycerol acyltransferase (DGAT), acyl CoA wax alcohol acyltransferase (AWAT) and monoacylglycerol acyltransferase (MGAT). (PubMed id 20374941)1, 7 Holmes R.S. (2010)
  7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 158835 HGNC: 23251 AceView: DGAT2L4 Ensembl:ENSG00000147160 euGenes: HUgn158835
ECgene: AWAT2 Kegg: 158835 H-InvDB: AWAT2

(According to HUGE)
About This Section
  --

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
  --

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from XenneX, Inc.)
About This Section
Patent Information for AWAT2 gene:
Search GeneIP for patents involving AWAT2

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
About This Section

 Millipore Custom Antibody & Bulk Services
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 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of AWAT2
 Search QIAGEN SeqTarget long-range PCR primers for resequencing for AWAT2
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of AWAT2
 GenScript Custom Purified and Recombinant Proteins Services for AWAT2 GenScript cDNA clones with any tag delivered in your preferred vector for AWAT2
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