Aliases &
Descriptions
for BAG1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| BCL2-associated athanogene1 2 | | glucocortoid receptor-associated protein RAP462 | | Bcl-2-associated athanogene 12 3 | | receptor-associated protein, 46-KD2 | | BAG-12 3 | | OTTHUMP000000211992 | | HAP2 3 | | BAG family molecular chaperone regulator 12 | | Bcl-2-binding protein2 | | Bcl-2 associating athanogene-1 protein2 | | RAP462 | | |
Export aliases for BAG1 gene to outside databasesPrevious GC identifers: GC09M033567 GC09M033423 GC09M033244 |
Summaries
for BAG1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for BAG1:
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death.The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances theanti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms.Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and threealternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. (provided byRefSeq)
UniProtKB/Swiss-Prot: BAG1_HUMAN, Q99933Function: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Inhibits the pro-apoptoticfunction of PPP1R15A, and has anti-apoptotic activity. Markedly increases the anti-cell death function of BCL2 inducedby various stimuli
Gene Wiki entry for BAG1 |
Genomic Views
for BAG1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the BAG1 gene promoter:
AP-1 Sox9 c-Jun c-Fos GR-alpha GR-beta p53 STAT3 FOXO1a IRF-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for BAG1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for BAG1  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9p12 Ensembl cytogenetic band: 9p13.3 HGNC cytogenetic band: 9p12BAG1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09M033245: view genomic region
(about GC identifiers)
Start:
|
33,209,370 bp from pter |
End:
|
33,221,664 bp from pter |
Size:
|
12,295 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr9- 33,247,818-33,264,761 |
RefSeq DNA sequence:- NC_000009.11 NT_008413.18
|
Proteins
for BAG1 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: BAG1_HUMAN, Q99933 (See
protein sequence)Recommended Name: BAG family molecular chaperone regulator 1 Size: 345 amino acids; 38779 Da
Subunit: Homodimer. Forms a heteromeric complex with HSP70/HSC70. Binds to the ATPase domain of HSP/HSC70 chaperones.Isoform 1, isoform 3 and isoform 4 but not isoform 2 interact with HSPA8/HSC70. Interacts with NR3C1. Interacts withthe N-terminal region of STK19. Interacts with PPP1R15A. Interacts with BCL2 in an ATP-dependent manner. Isoform 2does not interact with BCL2
Subcellular location: Isoform 1: Nucleus. Cytoplasm. Note=Isoform 1 localizes predominantly to the nucleus
Subcellular location: Isoform 2: Cytoplasm. Nucleus. Note=Isoform 2 localizes to the cytoplasm and shuttles into thenucleus in response to heat shock
Subcellular location: Isoform 4: Cytoplasm. Nucleus. Note=Isoform 4 localizes predominantly to the cytoplasm. Thecellular background in which it is expressed can influence whether it resides primarily in the cytoplasm or is alsofound in the nucleus. In the presence of BCL2, localizes to intracellular membranes (what appears to be the nuclearenvelope and perinuclear membranes) as well as punctate cytosolic structures suggestive of mitochondria
Sequence caution: Sequence=AAD11467.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=AAD25045.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAD96469.1;Type=Miscellaneous discrepancy; Note=Unusual initiator. The initiator methionine is coded by a non-canonical CTGleucine codon; Sequence=CAA84624.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=CAH72516.1; Type=Erroneous gene model prediction; Sequence=CAH72518.1; Type=Erroneous gene model prediction;Sequence=CAH72741.1; Type=Erroneous gene model prediction; Sequence=CAH72742.1; Type=Erroneous gene model prediction;Sequence=EAW58515.1; Type=Erroneous gene model prediction;
PDB structures from  and Proteopedia  :1HX1 (3D)
1WXV (3D)
3FZF (3D)
3FZH (3D)
3FZK (3D)
3FZL (3D)
3FZM (3D)
Secondary accessions: O75315 Q14414 Q53H32 Q5VZE8 Q5VZE9 Q5VZF0 Q96TG2 Q9Y2V4Alternative splicing, Alternative initiation: 4 isoforms: Q99933-1 Q99933-2 Q99933-3 Q99933-4 Explore the universe of human proteins at neXtProt for BAG1: NX_Q99933
Post-translational modifications:
Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation (Probable)1
REFSEQ proteins (2 alternative transcripts):
NP_001165886.1 NP_004314.5
ENSEMBL proteins: ENSP00000369026 ENSP00000420514 ENSP00000419092 ENSP00000369029 ENSP00000369022 ENSP00000417576
Human Recombinant Proteins
5/6 Gene Ontology (GO) cellular component terms (GO ID links to tree view) (see all 6): About this table
BAG1 for ontologies About GeneDecksing
Antibodies for BAG1:
Assays for BAG1: |
Protein
Domains/
Families
for BAG1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
BAG1 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q99933ProtoNet protein and cluster: Q99933 2 Blocks protein families: IPB000626 Ubiquitin domain IPB003103 Apoptosis regulator Bcl-2 protein
UniProtKB/Swiss-Prot: BAG1_HUMAN, Q99933Similarity: Contains 1 BAG domainSimilarity: Contains 1 ubiquitin-like domain |
Gene Function
for BAG1 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
UniProtKB/Swiss-Prot: BAG1_HUMAN, Q99933Function: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Inhibits the pro-apoptoticfunction of PPP1R15A, and has anti-apoptotic activity. Markedly increases the anti-cell death function of BCL2 inducedby various stimuliInduction: Up-regulated during differentiation of bladder epithelial cells and down-regulated during differentiation ofprostate epithelium
Genatlas biochemistry entry for BAG1:BCL2-associated athanogene 1 (antiapoptotic),negative regulator of Hsp70 chaperone activity,multifunctional proteininteracting with several types of proteins,including BCL2 family proteins,certain tyrosine-kinase receptors such ashepatocyte growth factor receptor (MET) and PDGFR and steroid receptors,mouse Bag1 homolog,with four isoforms (50,46(RAP46),33 and 29kDa),overexpressed in cervical,breast (invasive carcinomas) and lung cancer cell lines2 Gene Ontology (GO) molecular function terms (GO ID links to tree view): About this table
BAG1 for ontologies About GeneDecksing
Animal Models: 3 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Bag1):
BAG1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for BAG1 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
BAG1 for pathways About GeneDecksing
2  Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Pathways for BAG1
1  Kegg Pathway (Kegg details for BAG1):  | hsa04141 Protein processing in endoplasmic reticulum |
SABiosciences Pathway-Focused PCR Arrays including BAG1 (see all 4): PAHS-005A PAHS-012A
Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Molecular Interaction Network for BAG1
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for BAG1
5/11 Interacting proteins for BAG1 (Q999331, 2) via UniProtKB, MINT, and/or STRING (see all 11)About this table
5/11 Gene Ontology (GO) biological process terms (GO ID links to tree view) (see all 11): About this table
BAG1 for ontologies About GeneDecksing
|
Drugs & Compounds
for BAG1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
BAG1 for compounds About GeneDecksing
 Browse Tocris compounds for BAG1
10/19  Novoseek chemical compound relationships for BAG1 gene (see all 19)
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| n-(4-hydroxyphenyl)retinamide |
52 |
7 |
10772821 (6) |
| steroid |
38.1 |
23 |
10567384 (3), 15297164 (1), 17323428 (1), 9305631 (1) (see all 15) |
| nocodazole |
35.5 |
1 |
14532969 (1) |
| fludarabine |
31.3 |
4 |
16501812 (3) |
| paclitaxel |
30.9 |
2 |
15031599 (1), 18006758 (1) |
| vincristine |
22.7 |
1 |
17700523 (1) |
| cycloheximide |
18.3 |
3 |
19151744 (1) |
| estrogen |
17.8 |
20 |
18430249 (3), 15026618 (3), 19151744 (3), 16292491 (2) (see all 7) |
| progesterone |
16.3 |
11 |
18430249 (3), 15026618 (3), 15297164 (1), 12902980 (1) (see all 7) |
| atp |
13.9 |
3 |
9321400 (1), 9305631 (1), 11741305 (1) |
About this table
|
Transcripts
for BAG1 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for BAG1 gene (2 alternative transcripts): NM_001172415.1 NM_004323.5 Additional cDNA sequence: AF022224.1 AF116273.1 AK096038.1 AK222749.1 AK316577.1 BC001936.1 BC014774.1 CR600928.1 CR603873.1 CR605802.1 CR614940.1 CR618366.1 CR618567.1 U46917.1 Z35491.1 17 DOTS entries: DT.315269 DT.97839334 DT.100837530 DT.101963542 DT.111920 DT.100837517 DT.100837526 DT.100028750 DT.80100284 DT.100837522 DT.95343676 DT.111921 DT.75195442 DT.92407910 DT.95328823 DT.407507 DT.92439425 24/321 AceView cDNA sequences (see all 321): AI924567 BM981747 BU685423 BM702786 BM978241 CA944441 BM824290 BQ448659 CR614940 CF126150 CR618567 BM971376 BC001936 BQ017480 BQ668479 BM695593 CR618366 AI659059 AW206941 BC014774 CB306226 AA649985 BQ416718 BX363633
 highest scoring ESTs for BAG1:Z35491 AF022224 AW024280 AW024313 AW410499 BC001936 BC014774 BE260047 BE270208 BE336832 Unigene Cluster for BAG1: BCL2-associated athanogene Hs.377484 [show with all ESTs]Unigene Representative Sequence: NM_004323
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for BAG1
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 |
|---|
|
| SP1: | | | | | | | | | - | | | | | | - | | | | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for BAG1
11 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000379701 ENST00000467389 ENST00000379704(uc003zsj.2) ENST00000472232
ENST00000473781 ENST00000473464 ENST00000379707(uc003zsi.2 uc003zsk.2)
ENST00000379700 ENST00000493917 ENST00000488499 ENST00000468274
|
Expression
for BAG1 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| BAG1 expression in normal and diseased human tissues
1 / 2 / 3 13 probe-sets matching BAG1 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 80600_s_at2, 3
|
U95-E |
1 |
1.00 |
1.00 |
0.87 |
1.50 |
AW024280 |
0.80 |
1.00 |
0.91 |
1 |
| 34798_at2, 3
|
U95-A |
2 |
1.00 |
0.97 |
0.92 |
1.11 |
Z35491 |
1.00 |
1.00 |
1.00 |
1 |
| 71009_at2, 3
|
U95-E |
1 |
0.88 |
1.00 |
0.20 |
1.02 |
T97294 |
0.60 |
1.00 |
0.82 |
1 |
| 91754_at2, 3
|
U95-E |
1 |
0.56 |
1.00 |
0.58 |
0.22 |
AI564215 |
0.40 |
1.00 |
0.76 |
1 |
| 47643_at2, 3
|
U95-B |
1 |
0.50 |
1.00 |
-0.09 |
0.87 |
H10322 |
0.40 |
1.00 |
0.76 |
1 |
| 75499_at2, 3
|
U95-E |
1 |
0.44 |
1.00 |
0.63 |
0.97 |
AI191761 |
0.40 |
1.00 |
0.76 |
1 |
| 75105_f_at2, 3
|
U95-D |
1 |
0.31 |
1.00 |
0.79 |
1.33 |
AW024313 |
0.80 |
1.00 |
0.91 |
1 |
| 202387_at2, 3
|
U133-A |
1 |
1.00 |
1.00 |
-- |
-- |
NM_004323 |
0.60 |
1.00 |
0.82 |
1 |
| 211475_s_at2, 3
|
U133-A |
1 |
1.00 |
1.00 |
-- |
-- |
AF116273 |
0.60 |
1.00 |
0.82 |
1 |
| 229720_at2, 3
|
U133-B |
1 |
0.55 |
1.00 |
-- |
-- |
AA394039 |
0.20 |
1.00 |
0.72 |
1 |
| 202387_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 211475_s_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 229720_at2
|
U133Plus2 |
1 |
0.55 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
BAG1 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: TTAATTGGGA
SOURCE GeneReport for Unigene cluster: Hs.377484
Expression variation in blood from EXPOLDB for BAG1 UniProtKB/Swiss-Prot: BAG1_HUMAN, Q99933Tissue specificity: Isoform 4 is the most abundantly expressed isoform. It is ubiquitously expressed throughout mosttissues, except the liver, colon, breast and uterine myometrium. Isoform 1 is expressed in the ovary and testis.Isoform 4 is expressed in several types of tumor cell lines, and at consistently high levels in leukemia and lymphomacell lines. Isoform 1 is expressed in the prostate, breast and leukemia cell lines. Isoform 3 is the least abundantisoform in tumor cell lines (at protein level)
SABiosciences Expression via Pathway-Focused PCR Arrays including BAG1 (see all 4): PAHS-005A PAHS-012A
|
Orthologs
for BAG1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for BAG1 gene from 5/7 species (see all 7)
About this table Species with no ortholog for BAG1
ENSEMBL Gene Tree for BAG1 (if available) |
Paralogs
for BAG1 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Pseudogenes
- 2 related pseudogenes
|
Genomic Variants
for BAG1 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 9 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for BAG1 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for BAG1
1 CNV: 100626 | | QIAGEN SeqTarget long-range PCR primers for resequencing BAG1 |
|
Disorders & Mutations
for BAG1 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
Novoseek, PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
BAG1 for disorders About GeneDecksing
OMIM: 601497
10/26 Novoseek disease relationships for BAG1 gene (see all 26)
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| shock |
57.7 |
25 |
11494137 (2), 12558971 (2), 15003494 (2), 12874020 (2) (see all 15) |
| breast cancer |
44.8 |
75 |
10576663 (5), 11181661 (5), 15026618 (4), 19151744 (4) (see all 24) |
| cancer |
35.5 |
34 |
12373595 (5), 10772821 (2), 15297164 (2), 15033003 (2) (see all 16) |
| tumors |
25.4 |
36 |
18795671 (3), 10467399 (3), 18430249 (2), 11494232 (2) (see all 20) |
| breast carcinoma |
24.7 |
9 |
10561207 (4), 15026618 (2), 19243896 (2), 19066611 (1) |
| carcinoma |
22.9 |
30 |
17549665 (5), 20096920 (4), 16457154 (3), 19620938 (2) (see all 11) |
| metastasis |
20.1 |
18 |
17657847 (3), 19620938 (2), 10964051 (1), 20096920 (1) (see all 10) |
| cervical carcinoma |
18.1 |
5 |
10772821 (2), 10047462 (2), 12370827 (1) |
| colon carcinoma |
17 |
8 |
17657847 (8) |
| adenoma |
15 |
14 |
12845674 (4), 20096920 (2), 16042572 (2), 15560850 (2) (see all 5) |
About this table
Genetic Association Database (GAD): BAG1
Human Genome Epidemiology (HuGE) Navigator: BAG1 (6 documents)
Export disorders and mutations for BAG1 gene to outside databases
|
Medical News
for BAG1 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for BAG1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
10/208 PubMed articles for BAG1 gene, integrated from 7 sources (see all 208):
(articles sorted by number of sources associating them with BAG1)- Expression and location of Hsp70/Hsc-binding anti-apoptotic protein BAG-1 and its variants in normal tissues and tumor cell lines. (PubMed id 9679980)1, 2, 7 Takayama S.... Reed J.C. (1998)
- BAG-1 modulates the chaperone activity of Hsp70/Hsc70. (PubMed id 9305631)1, 2, 7 Takayama S.... Reed J.C. (1997)
- Mammalian cells express two differently localized Bag-1 isoforms generated by alternative translation initiation. (PubMed id 9396724)1, 2, 7 Packham G.... Cleveland J.L. (1997)
- p53-inducible human homologue of Drosophila seven in absentia (Siah) inhibits cell growth: suppression by BAG-1. (PubMed id 9582267)1, 2, 7 Matsuzawa S.... Reed J.C. (1998)
- Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity. (PubMed id 7834747)1, 3, 7 Takayama S....Reed J.C. (1995)
- Human BAG-1 proteins bind to the cellular stress response protein GADD34 and interfere with GADD34 functions. (PubMed id 12724406)1, 2, 7 Hung W.J.... Wu D.Y. (2003)
- An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators. (PubMed id 9873016)1, 2, 7 Takayama S.... Reed J.C. (1999)
- Characterization of Hap/BAG-1 variants as RP1 binding proteins with antiapoptotic activity. (PubMed id 15986447)1, 2 Wadle A.... Renner C. (2005)
- Screening for candidate gene regions in narcolepsy using a microsatellite based approach and pooled DNA. (PubMed id 15309313)1, 4 Wieczorek S....Epplen J.T. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
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External Searches for BAG1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing BAG1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing BAG1 gene
(According to HUGE)
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Specialized Databases showing BAG1 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Patent Information for BAG1 gene:
Search GeneIP for patents involving BAG1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for BAG1 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
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 | Antibodies & Assays for BAG1 |
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