Aliases &
Descriptions
for BAIAP3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| BAI1-associated protein 31 2 | | BAP31 2 3 5 | | KIAA07341 2 3 | | MGC1383342 | | OTTHUMP000001586512 | | BAI-associated protein 32 |
Export aliases for BAIAP3 gene to outside databasesPrevious GC identifers: GC16P001400 GC16P001324 |
Summaries
for BAIAP3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for BAIAP3:
This p53-target gene encodes a brain-specific angiogenesis inhibitor. The protein is a seven-span transmembrane proteinand a member of the secretin receptor family. It interacts with the cytoplasmic region of brain-specific angiogenesisinhibitor 1. This protein also contains two C2 domains, which are often found in proteins involved in signaltransduction or membrane trafficking. Its expression pattern and similarity to other proteins suggest that it may beinvolved in synaptic functions. Several transcript variants encoding different isoforms have been found for this gene.(provided by RefSeq)
Gene Wiki entry for BAIAP3 |
Genomic Views
for BAIAP3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the BAIAP3 gene promoter:
AP-1 p300 c-Fos c-Jun GR-alpha deltaCREB CREB RFX1 PPAR-gamma1 PPAR-gamma2
Other transcription factors
Search SABiosciences Chromatin IP Primers for BAIAP3
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for BAIAP3  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3BAIAP3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P001383: view genomic region
(about GC identifiers)
Start:
|
1,312,713 bp from pter |
End:
|
1,327,840 bp from pter |
Size:
|
15,128 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr16+ 1,383,654-1,399,440 |
RefSeq DNA sequence:- NC_000016.9 NT_010393.16
|
Proteins
for BAIAP3 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: BAIP3_HUMAN, O94812 (See
protein sequence)Recommended Name: BAI1-associated protein 3 Size: 1187 amino acids; 131901 Da
Subunit: Interacts with BAI1
Sequence caution: Sequence=BAA34454.2; Type=Erroneous initiation;
Secondary accessions: B2RCD7 O94839 Q2M226 Q658J2 Q76N05 Q96RZ3 Q9UJK1Alternative splicing: 2 isoforms: O94812-1 O94812-2 Explore the universe of human proteins at neXtProt for BAIAP3: NX_O94812
Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins (5 alternative transcripts):
NP_001186025.1 NP_001186026.1 NP_001186027.1 NP_001186028.1 NP_003924.2
ENSEMBL proteins: ENSP00000380626 ENSP00000394174 ENSP00000380625 ENSP00000407242 ENSP00000409533 ENSP00000324510
Human Recombinant Proteins
Antibodies for BAIAP3:
Assays for BAIAP3: |
Protein
Domains/
Families
for BAIAP3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
BAIAP3 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry O94812ProtoNet protein and cluster: O94812 2 Blocks protein families: IPB000008 C2 domain IPB010439 Protein of unknown function DUF1041
UniProtKB/Swiss-Prot: BAIP3_HUMAN, O94812Similarity: Contains 2 C2 domainsSimilarity: Contains 1 MHD1 (MUNC13 homology domain 1) domainSimilarity: Contains 1 MHD2 (MUNC13 homology domain 2) domain |
Gene Function
for BAIAP3 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
Genatlas biochemistry entry for BAIAP3:brain-specific angiogenesis inhibitor (BAI1)-associated protein 3,predominantly expressed in brain,homolog tosynaptotagmin,potentially regulating the release of neurotransmitters2 Gene Ontology (GO) molecular function terms (GO ID links to tree view): About this table
BAIAP3 for ontologies About GeneDecksing
|
Pathways & Interactions
for BAIAP3 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for BAIAP3
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for BAIAP3
4 Interacting proteins for BAIAP3 (ENSP000003245103 O948121) via UniProtKB, MINT, and/or STRINGAbout this table
2 Gene Ontology (GO) biological process terms (GO ID links to tree view): About this table
BAIAP3 for ontologies About GeneDecksing
|
Drugs & Compounds
for BAIAP3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for BAIAP3
|
Transcripts
for BAIAP3 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for BAIAP3 gene (5 alternative transcripts): NM_001199096.1 NM_001199097.1 NM_001199098.1 NM_001199099.1 NM_003933.4 Additional cDNA sequence: AB018277.2 AF038191.1 AK294491.1 AK294576.1 AK294744.1 AK295645.1 AK299309.1 AK299358.1 AK315059.1 AL834321.1 BC104966.1 BC112129.1 8 DOTS entries: DT.75118306 DT.100815748 DT.100815756 DT.95161516 DT.120662077 DT.120662127 DT.92434995 DT.91706459 24/87 AceView cDNA sequences (see all 87): CB148214 BM981388 BF448577 CB153038 AB018277 BQ425972 CD251629 CB155761 AI564977 CD106045 BM827931 BQ277755 BI771405 AI696810 NM_003933 BP348862 AL041518 BM544695 BU790170 BM828573 BU854755 F13300 BE869971 BQ632058
 highest scoring ESTs for BAIAP3:AB018277 AA078749 AA079823 AA682952 AA782001 AI358964 AI537389 AI564977 AI696810 AI816746 Unigene Cluster for BAIAP3: BAI1-associated protein 3 Hs.458427 [show with all ESTs]Unigene Representative Sequence: AL834321
GeneLoc Exon Structure
5/24 Alternative Splicing Database (ASD) splice patterns (SP) for BAIAP3 (see all 24)
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | · | 11c | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ | 14 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 15a | · | 15b | · | 15c | · | 15d | ^ | 16a | · | 16b | · | 16c | ^ | 17a | · | 17b | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21a | · | 21b | · | 21c | ^ | 22 | ^ | 23a | · | 23b | ^ | 24a | · | 24b | ^ | 25a | · | 25b | · | 25c | ^ | 26 | ^ | 27a | · | 27b | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 28a | · | 28b | · | 28c | ^ | 29 | ^ | 30a | · | 30b | ^ | 31 | ^ | 32 | ^ | 33a | · | 33b | ^ | 34 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | - | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP5: | - | | | | | | | | | | | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for BAIAP3
6 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000397489 ENST00000440627 ENST00000397488(uc002clj.2 uc010uuz.1 uc010uva.1 uc010uvc.1)
ENST00000426824 ENST00000421665(uc010uvb.1) ENST00000324385(uc002clk.1)
|
Expression
for BAIAP3 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| BAIAP3 expression in normal and diseased human tissues
1 / 2 / 3 5 probe-sets matching BAIAP3 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 41115_s_at2, 3
|
U95-A |
1 |
0.62 |
1.00 |
1.00 |
1.00 |
AB018277 |
1.00 |
1.00 |
1.00 |
1 |
| 216356_x_at2, 3
|
U133-A |
1 |
0.82 |
1.00 |
-- |
-- |
AB018277 |
1.00 |
1.00 |
1.00 |
1 |
| 204874_x_at2, 3
|
U133-A |
1 |
0.64 |
1.00 |
-- |
-- |
NM_003933 |
0.60 |
1.00 |
0.82 |
1 |
| 216356_x_at2
|
U133Plus2 |
1 |
0.82 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 204874_x_at2
|
U133Plus2 |
1 |
0.64 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
BAIAP3 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.458427
Expression variation in blood from EXPOLDB for BAIAP3 UniProtKB/Swiss-Prot: BAIP3_HUMAN, O94812Tissue specificity: Predominantly expressed in brain
SABiosciences Custom PCR Arrays for BAIAP3
|
Orthologs
for BAIAP3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for BAIAP3 gene from 5/9 species (see all 9)
About this table Species with no ortholog for BAIAP3
ENSEMBL Gene Tree for BAIAP3 (if available) |
Paralogs
for BAIAP3 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for BAIAP3 gene
- UNC13C2 UNC13A2 UNC13D2 UNC13B2
BAIAP3 for paralogs About GeneDecksing
|
Genomic Variants
for BAIAP3 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 16 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for BAIAP3 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for BAIAP3
2 CNVs: 29991 5329 | | QIAGEN SeqTarget long-range PCR primers for resequencing BAIAP3 |
|
Disorders & Mutations
for BAIAP3 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
BAIAP3 for disorders About GeneDecksing
OMIM: 604009
Export disorders and mutations for BAIAP3 gene to outside databases
|
Medical News
for BAIAP3 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for BAIAP3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
10/16 PubMed articles for BAIAP3 gene, integrated from 7 sources (see all 16):
(articles sorted by number of sources associating them with BAIAP3)- Cloning and characterization of BAP3 (BAI-associated protein 3), a C2 domain-containing protein that interacts with BAI1. (PubMed id 9790924)1, 2, 3, 7 Shiratsuchi T.... Nakamura Y. (1998)
- The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)1, 2 Martin J.... Pennacchio L.A. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
- Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. (PubMed id 11157797)1, 2 Daniels R.J....Higgs D.R. (2001)
- Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9872452)1, 2 Nagase T.... Ohara O. (1998)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)1 Wiemann S....Poustka A. (2004)
|
External Searches for BAIAP3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing BAIAP3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing BAIAP3 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing BAIAP3 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for BAIAP3 gene:
Search GeneIP for patents involving BAIAP3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for BAIAP3 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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| |  | Search Tocris compounds for BAIAP3 |
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