Aliases &
Descriptions
for C4orf21 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| chromosome 4 open reading frame 211 2 | | OTTHUMP000001638252 | | FLJ113311 2 | | OTTHUMP000002182362 | | DKFZp313L2262 | | DKFZp434C09272 | | FLJ332372 | | OTTHUMP000002197642 | | prematurely terminated mRNA decay factor-like2 | | FLJ440662 |
Export aliases for C4orf21 gene to outside databasesPrevious GC identifers: GC04M113730 GC04M113483 |
Summaries
for C4orf21 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C4orf21 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C4orf21 gene promoter:
RREB-1 ATF POU2F1 FOXO4 CREB deltaCREB YY1 E2F E2F-1 c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for C4orf21
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for C4orf21  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q25 Ensembl cytogenetic band: 4q25 HGNC cytogenetic band: 4q25C4orf21 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04M109192: view genomic region
(about GC identifiers)
Start:
|
109,192,191 bp from pter |
End:
|
109,286,555 bp from pter |
Size:
|
94,365 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr4- 113,460,492-113,558,151 |
RefSeq DNA sequence:- NC_000004.11 NT_016354.19
|
Proteins
for C4orf21 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: CD021_HUMAN, Q86YA3 (See
protein sequence)Recommended Name: Uncharacterized protein C4orf21 Size: 1062 amino acids; 119347 Da
Secondary accessions: Q9NUJ4Alternative splicing: 2 isoforms: Q86YA3-1 Q86YA3-2 Explore the universe of human proteins at neXtProt for C4orf21: NX_Q86YA3
Post-translational modifications:
View phosphorylation sites using PhosphoSite2 (C4orf21)
REFSEQ proteins: NP_060862.3
ENSEMBL proteins: ENSP00000424737 ENSP00000404365 ENSP00000426938 ENSP00000309095 ENSP00000424946 ENSP00000424995 ENSP00000424429 ENSP00000317088 ENSP00000390505
Human Recombinant Proteins
2 Gene Ontology (GO) cellular component terms (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016020 | membrane |
IEA | -- | | GO:0016021 | integral to membrane |
IEA | -- |
About this table
C4orf21 for ontologies About GeneDecksing
Antibodies for C4orf21:
Assays for C4orf21: |
Protein
Domains/
Families
for C4orf21 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
C4orf21 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q86YA3ProtoNet protein and cluster: Q86YA3 |
Gene Function
for C4orf21 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
1 Gene Ontology (GO) molecular function term (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008270 | zinc ion binding |
IEA | -- |
About this table
C4orf21 for ontologies About GeneDecksing
|
Pathways & Interactions
for C4orf21 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for C4orf21
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C4orf21
|
Drugs & Compounds
for C4orf21 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for C4orf21
|
Transcripts
for C4orf21 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for C4orf21 gene: NM_018392.4 Additional cDNA sequence: AK002193.1 AK090556.1 AK126054.1 AK299831.1 AK302613.1 AL137700.1 BC028584.2 BC044799.1 BX647594.1 12 DOTS entries: DT.97771568 DT.300709 DT.104187 DT.97790559 DT.40278041 DT.97763250 DT.100730059 DT.100693104 DT.100811375 DT.91647074 DT.75106326 DT.97777216 24/74 AceView cDNA sequences (see all 74): AW021355 BQ010217 CN484639 BX279541 BX647594 AU139409 AA683145 AK126054 AX746508 BC044799 AA972753 AA931632 AW449458 AW169469 AI733193 BE327659 BP350173 AL137700 NM_138698 BC028584 BE217866 AK002193 AK090556 BP369240
 highest scoring ESTs for C4orf21:AA215455 BC044799 BG615985 BG771623 BG943861 BQ230118 AK002193 CN297342 CN297343 DA802797 Unigene Cluster for C4orf21: Chromosome 4 open reading frame 21 Hs.380346 [show with all ESTs]Unigene Representative Sequence: NM_018392
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for C4orf21
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | · | 7c | · | 7d | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 |
|---|
|
| SP1: | | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP2: | | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for C4orf21
12 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000505019(uc003iav.2 uc003iau.2) ENST00000445413 ENST00000506675(uc003iat.2)
ENST00000473015 ENST00000309071(uc003iaw.2) ENST00000264370 ENST00000514770
ENST00000503172 ENST00000512075 ENST00000502805 ENST00000313239 ENST00000445203
|
Expression
for C4orf21 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| C4orf21 expression in normal and diseased human tissues
1 / 2 / 3 6 probe-sets matching C4orf21 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 77711_at2, 3
|
U95-E |
1 |
1.00 |
1.00 |
0.02 |
0.21 |
AA215455 |
0.80 |
0.88 |
0.84 |
1 |
| 81204_at2, 3
|
U95-E |
2 |
1.00 |
0.59 |
1.00 |
1.00 |
AI553943 |
0.20 |
0.12 |
0.17 |
2 |
| 231204_at2, 3
|
U133-B |
1 |
1.00 |
1.00 |
-- |
-- |
AU158002 |
0.60 |
0.83 |
0.73 |
1 |
| 228859_at2, 3
|
U133-B |
2 |
1.00 |
0.68 |
-- |
-- |
BF056790 |
0.20 |
0.17 |
0.18 |
2 |
| 231204_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 228859_at2
|
U133Plus2 |
2 |
1.00 |
0.68 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
C4orf21 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: TAAAAATTTT
SOURCE GeneReport for Unigene cluster: Hs.380346
SABiosciences Custom PCR Arrays for C4orf21
|
Orthologs
for C4orf21 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
| ENSEMBL Gene Tree for C4orf21 (if available) |
Paralogs
for C4orf21 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for C4orf21 gene
- HELZ2 MOV10L12 PRIC2852 MOV102 UPF12
C4orf21 for paralogs About GeneDecksing
|
Genomic Variants
for C4orf21 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 4 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for C4orf21 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 8 variations for C4orf21
2 CNVs: 23071 98850
6 Indels: 12526 40675 62251 12525 46481 41858 | | QIAGEN SeqTarget long-range PCR primers for resequencing C4orf21 |
|
Disorders & Mutations
for C4orf21 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
C4orf21 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: C4orf21 (1 document)
Export disorders and mutations for C4orf21 gene to outside databases
|
Medical News
for C4orf21 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for C4orf21 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
10/13 PubMed articles for C4orf21 gene, integrated from 7 sources (see all 13):
(articles sorted by number of sources associating them with C4orf21)- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- A systematic gene-based screen of chr4q22-q32 identif ies association of a novel susceptibility gene, DKK2, with the quantitative tra it of alcohol dependence symptom counts. (PubMed id 20332099)1 Kalsi G....Riley B.P. (2010)
- Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (2009)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)1 Bechtel S.... Schupp I. (2007)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1 Olsen J.V....Mann M. (2006)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
|
External Searches for C4orf21 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C4orf21 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C4orf21 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C4orf21 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for C4orf21 gene:
Search GeneIP for patents involving C4orf21
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C4orf21 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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