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CA10 Gene

protein-coding   GIFtS: 53

GC17M045077
carbonic anhydrase X
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

Aliases &
Descriptions
for CA10 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases & Descriptions
carbonic anhydrase X1 2     Cerebral protein 152 3
CARPX1 2 5     CA-RP X2 3
CA-RPX1 2     CARP X2 3
HUCEP-151 2     carbonic anhydrase-related protein 102
Carbonic anhydrase-related protein X2 3     cerebral protein-152

External Ids:    HGNC: 13691   Entrez Gene: 569342   Ensembl: ENSG000001549757   UniProtKB: Q9NS853   

Export aliases for CA10 gene to outside databases

Previous GC identifers: GC17U990008 GC17M052189 GC17M050049 GC17M050182 GC17M047062 GC17M049707


Summaries
for CA10 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for CA10:
This gene encodes a protein that belongs to the carbonic anhydrase family of zinc metalloenzymes, which catalyze the
reversible hydration of carbon dioxide in various biological processes. The protein encoded by this gene is an
acatalytic member of the alpha-carbonic anhydrase subgroup, and it is thought to play a role in the central nervous
system, especially in brain development. Multiple transcript variants encoding the same protein have been found for
this gene. (provided by RefSeq)

UniProtKB/Swiss-Prot: CAH10_HUMAN, Q9NS85
Function: Does not have a catalytic activity

Gene Wiki entry for CA10

Genomic Views
for CA10 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CA10 gene promoter:
         HOXA9B   Meis-1   Bach1   NF-kappaB1   NF-kappaB   NF-kappaB2   FOXO1a   LCR-F1   Pax-6   ATF-2   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for CA10

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for CA10 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.33   Ensembl cytogenetic band:  17q22   HGNC cytogenetic band: 17q21

CA10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CA10 gene location

GeneLoc gene densities for chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M045077:  view genomic region     (about GC identifiers)

Start:
 45,077,023 bp from pter
End:
 45,606,524 bp from pter
Size:
 529,502 bases
Orientation:
 minus strand

1 alternative location:
Chr17- 49,707,675-50,237,377     
RefSeq DNA sequence:
NC_000017.10  NT_010783.15  

Proteins
for CA10 gene

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section
UniProtKB/Swiss-Prot: CAH10_HUMAN, Q9NS85 (See protein sequence)
Recommended Name: Carbonic anhydrase-related protein 10  
Size: 328 amino acids; 37563 Da
Developmental stage: Not expressed in fetal brain
Secondary accessions: B2R7J0

Explore the universe of human proteins at neXtProt for CA10: NX_Q9NS85 

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins (3 alternative transcripts): 
    NP_001076002.1  NP_001076003.1  NP_064563.1  


    ENSEMBL proteins: 
    ENSP00000390666 ENSP00000285273 ENSP00000405388 ENSP00000340363 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich
    R&D Systems Recombinant & Natural Proteins for CA10 (Carbonic Anhydrase X/CA10)
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: CA10
    GenScript Custom Purified and Recombinant Proteins Services for CA10 
    Novus Biologicals Proteins for CA10
    Novus Biologicals Lysates for CA10
    Sino Biological Recombinant Protein for CA10
    Browse ProSpec Recombinant Proteins

    1 Gene Ontology (GO) cellular component term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575 cellular_component ND--
    About this table

    CA10 for ontologies           About GeneDecksing



    Antibodies for CA10: 
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for CA10
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    GenScript Custom Superior Antibodies Services for CA10 
    Novus Biologicals Antibodies for CA10
    Browse antibodies at Epitomics

    Assays for CA10: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CA10 
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for CA10 

    Protein Domains/
    Families
    for CA10 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    CA10 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR001148 Carbonic_anhydrase_a-class_cat
     IPR018423 Carbonic_anhydrase-RP_CA10

    Graphical View of Domain Structure for InterPro Entry Q9NS85

    ProtoNet protein and cluster: Q9NS85

    1 Blocks protein family: IPB001148 Carbonic anhydrase

    UniProtKB/Swiss-Prot: CAH10_HUMAN, Q9NS85
    Similarity: Belongs to the alpha-carbonic anhydrase family


    Gene Function
    for CA10 gene

    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    UniProtKB/Swiss-Prot: CAH10_HUMAN, Q9NS85
    Function: Does not have a catalytic activity

    Inhib.
    RNA:            		Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich siRNA Panels and esiRNA and siRNA for CA10
    Sigma-Aldrich shRNA for CA10
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 3): CA10
    OriGene shRNA RFP (see all 3): CA10
    OriGene basic RS shRNA (see all 3): CA10
    OriGene siRNA (see all 3): CA10
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of CA10 
    miRNA:Sigma-Aldrich microRNA Mimics for CA10
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of CA10 
    2 SABiosciences Assays for microRNAs that regulate CA10:
    hsa-miR-27a hsa-miR-27b

    Gene
    Editing:    		Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): CA10
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): CA10
    OriGene untagged cDNA clones in CMV expression vector (see all 3): CA10
    OriGene 3'-UTR clone (see all 3): CA10 
    Browse MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for CA10 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:          		GenScript Custom overexpressing Cell Line Services for CA10 

    1 Gene Ontology (GO) molecular function term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674 molecular_function ND11311946
    About this table

    CA10 for ontologies           About GeneDecksing


    Pathways & Interactions
    for CA10 gene

    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section


    CA10 for pathways           About GeneDecksing

    1 Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Pathway for  CA10
        Nitrogen Metabolism

        SABiosciences Custom Pathway-Focused PCR Arrays for CA10 

        Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Molecular Interaction Network for CA10
        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CA10

    1 Gene Ontology (GO) biological process term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007420 brain development NAS11311946
    About this table

    CA10 for ontologies           About GeneDecksing



    Drugs & Compounds
    for CA10 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section
    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CA10


    Transcripts
    for CA10 gene

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section
    Inhib.
    RNA:             		Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich siRNA Panels and esiRNA and siRNA for CA10
    Sigma-Aldrich shRNA for CA10
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 3): CA10
    OriGene shRNA RFP (see all 3): CA10
    OriGene basic RS shRNA (see all 3): CA10
    OriGene siRNA (see all 3): CA10
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of CA10 
    miRNA: Sigma-Aldrich microRNA Mimics for CA10
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of CA10 
    2 SABiosciences Assays for microRNAs that regulate CA10:
    hsa-miR-27a hsa-miR-27b
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): CA10
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): CA10
    OriGene untagged cDNA clones in CMV expression vector (see all 3): CA10
    OriGene 3'-UTR Clone (see all 3): CA10 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for CA10 
    Primers: OriGene genome-wide validated SYBR primer pairs: CA10
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for CA10: PPH15895A

    REFSEQ mRNAs for CA10 gene (3 alternative transcripts): 

    NM_001082533.1  NM_001082534.1  NM_020178.4  

    Additional cDNA sequence: 

    AB001597.1 AB036836.1 AF288385.1 AK294652.1 AK313001.1 AL161812.1 AY358509.1 BC020577.1 
    BC029865.1 BC047456.1 BC068462.1 CR597480.1 CR609088.1 CR749607.1 

    8 DOTS entries:

    DT.97816776  DT.97784104  DT.92041233  DT.100837832  DT.446487  DT.75114486  DT.92418770  DT.120993495 

    24/98 AceView cDNA sequences (see all 98):

    BX281234 BC047456 AY358509 AI470807 AI815617 AF288385 AA709457 AA063170 
    CR749607 T30964 CR609088 F06106 AA716317 BM703408 AA723288 BM723566 
    AI074499 F05437 BF934583 F11600 AI338414 Z41624 H10857 Z40949 

    highest scoring ESTs for CA10:

    AB036836 AF288385 AI815617 AI815895 AL161812 AY358509 BC020577 BC029865 BC047456 BC068462 

    Unigene Cluster for CA10:

    Carbonic anhydrase X
    Hs.463466  [show with all ESTs]
    Unigene Representative Sequence: NM_001082533


    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for CA10 (see all 7)

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b
    SP1:                                                        -     -                                             
    SP2:                                                                                                            
    SP3:                                                              -                                             
    SP4:              -     -                                                                                       
    SP5:              -     -                                                                                       

    About this scheme

    ECgene alternative splicing isoforms for CA10
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000442502(uc002ity.3 uc002itz.2) ENST00000285273(uc002itx.3)
    ENST00000451037(uc002itv.3 uc002itw.3) ENST00000340813(uc002itu.3)


    Expression
    for CA10 gene

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    CA10 expression in normal and diseased human tissues

    1  / 2  / 3

    6 probe-sets matching CA10 gene

    Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    50694_at2, 3 U95-B 1 1.00 1.00 0.97 1.47 AI815895 0.80 1.00 0.91 1
    46593_at2, 3 U95-B 1 1.00 1.00 0.99 0.69 H15418 0.80 1.00 0.91 1
    223550_s_at2, 3 U133-B 1 1.00 1.00 -- -- AF288385 0.80 1.00 0.91 1
    220889_s_at2, 3 U133-A 1 1.00 1.00 -- -- NM_020178 0.60 1.00 0.82 1
    223550_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    220889_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    About this table

    CA10 for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    CA10 gene expression
    CA10 gene electronic northern expression
    CA10 gene sage expression
    About these images

    CGAP SAGE TAG: CCCCCCTGTG

    SOURCE GeneReport for Unigene cluster: Hs.463466

    UniProtKB/Swiss-Prot: CAH10_HUMAN, Q9NS85
    Tissue specificity: Strong expression in brain and central nervous system

    Primers: OriGene genome-wide validated SYBR primer pairs: CA10
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for CA10: PPH15895A
        SABiosciences Custom PCR Arrays for CA10 


    Orthologs
    for CA10 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for CA10 gene from 5/8 species (see all 8)
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 CA101   -- carbonic anhydrase X 96.85(n)
    100(a)    		 609477  XM_847686.1  XP_852779.1 
    chimpanzee
    (Pan troglodytes)    		 CA101   -- carbonic anhydrase X 99.8(n)
    100(a)    		 455136  XM_001171487.1  XP_001171487.1 
    mouse
    (Mus musculus)    		 Car101 , 5 11 (58.43 cM)5
    		 carbonic anhydrase 101, 5 94.51(n)1
    100(a)1    		 726051  NM_028296.21  NP_082572.11 
     AB0807415  AK0123025  (see all 18)
    chicken
    (Gallus gallus)    		 CA101   -- carbonic anhydrase X 86.79(n)
    99.39(a)    		 417389  XM_415644.2  XP_415644.1 
    zebrafish
    (Danio rerio)    		 wufd54f062   -- Transcribed sequence with moderate similarity to protein spQ9NS85 (H.sapiens) CAHA_HUMAN Carbonic anhydrase-related protein 10 (Carbonic anhydrase-related protein X) (CARP X) (CA-RP X) less 79.26(n)  AL915399.1 
    About this table        Species with no ortholog for CA10

    ENSEMBL Gene Tree for CA10 (if available)

    Paralogs
    for CA10 gene

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
    Paralogs for CA10 gene
    CA122  CA62  CA42  CA112  CA92  CA142  

    CA10 for paralogs           About GeneDecksing



    Genomic Variants
    for CA10 gene

    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/5111 NCBI SNPs in CA10 are shown (see all 5111)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 17 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ----------
    rs132931,2
    		--49708539(+) ACAAAG/AGCTGA 3 -- ut311Minor allele frequency- A:0.00MN 184
    rs255971,2
    		--49724353(+) GGATC-/TCTT  
                TCTTT     		3 -- int10--------
    rs646361,2
    		C,F,A,49984205(-) gcaagA/Caggac 3 -- int117Minor allele frequency- G:0.08NS MN EA NA WA 986
    rs691781,2
    		C,F,O,A,50012297(+) CTGTGA/GAAACA 3 -- int122Minor allele frequency- G:0.47NA NS EA WA 1306
    rs1235261,2
    		C,F,O,A,H,50012558(+) AATGCC/TGTGGC 3 -- int116Minor allele frequency- T:0.35NA EA WA 760
    rs1235271,2
    		C,A,H,50012658(+) AACTTT/ATATTT 3 -- int19Minor allele frequency- A:0.48NA EA WA 222
    rs1693841,2
    		C,F,A,H,50090324(+) ACCAAC/TGTAGC 3 -- int110Minor allele frequency- T:0.47EA NS NA WA 500
    rs1693851,2
    		C,F,H,50034554(+) ATTTCT/GTAACG 3 -- int111Minor allele frequency- G:0.02NS EA NA WA 436
    rs1693861,2
    		C,F,A,H,50062780(+) caaaaA/Cgttga 3 -- int122Minor allele frequency- C:0.10NS EA NA 1418
    rs1693871,2
    		C,F,O,A,H,50005964(+) AACATA/GTAGTT 3 -- int117Minor allele frequency- G:0.34MN NA NS EA WA 970
    About this table

    HapMap Linkage Disequilibrium images for CA10 (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 14 variations for CA10
         4 CNVs: 67221 61576 102481 47874
         10 Indels: 88536 88532 77663 42936 77664 88531 88533 77665 88535 88534

    QIAGEN SeqTarget long-range PCR primers for resequencing CA10 

    Disorders & Mutations
    for CA10 gene

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    CA10 for disorders           About GeneDecksing

    OMIM: 604642

    Human Genome Epidemiology (HuGE) Navigator: CA10 (4 documents)

    Export disorders and mutations for CA10 gene to outside databases

    Medical News
    for CA10 gene

    (Possibly Related Articles in Doctor's Guide)
    About This Section
    		   --

    Publications
    for CA10 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/18 PubMed articles for CA10 gene, integrated from 7 sources (see all 18):
    (articles sorted by number of sources associating them with CA10)
    1. CCG repeats in cDNAs from human brain. (PubMed id 9921901)1, 2, 3 Kleiderlein J.J.... Margolis R.L. (1998)
    2. cDNA sequence of human carbonic anhydrase-related protein, CA-RP X: mRNA expressions of CA-RP X and XI in human brain. (PubMed id 11311946)1, 2, 7 Okamoto N.... Onishi S. (2001)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    6. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    7. Functional diversity, conservation, and convergence in the evolution of the alpha-, beta-, and gamma-carbonic anhydrase gene families. (PubMed id 8673298)1, 3 Hewett-Emmett D. and Tashian R.E. (1996)
    8. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    9. Nucleotide variations in genes encoding carbonic anhydrase 8 and 10 associated with femoral bone mineral density in Japanese female with osteoporosis. (PubMed id 19172221)1 Mori S....Ikegawa S. (2009)
    10. Coeliac disease associated risk variants in TNFAIP3 and REL implicate altered NF-{kappa}B signalling. (PubMed id 19240061)1 Trynka G....Wijmenga C. (2009)

    External Searches for CA10 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing CA10 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 56934 HGNC: 1369 AceView: CA10 Ensembl:ENSG00000154975 euGenes: HUgn56934
    ECgene: CA10 H-InvDB: CA10

    Other Databases showing CA10 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing CA10 gene

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    		   --

    Intellectual Property
    for CA10 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
    About This Section
    		Patent Information for CA10 gene:
    Search GeneIP for patents involving CA10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for CA10 gene

    (Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
    Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
    About This Section

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services

     Predesigned and custom siRNAs for CA10 Antibodies for CA10
     Super-pooled esiRNAs for CA10 Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for CA10 microRNA Mimics for CA10
     "Your Favorite Gene" Pathways and Molecular Interaction Networks Browse Nano Scale siRNA at Sigma-Aldrich
     Browse iPSC Reprogramming Factors at Sigma-Aldrich Browse small molecules at Sigma-Aldrich
     Browse FLAG tag genes at Sigma-Aldrich Browse ELISAs at Sigma-Aldrich
     Browse microRNA Target Validation Systems at Sigma-Aldrich Browse CompoZr Knockout ZFN at Sigma-Aldrich
    feedback
      
     Antibodies   Cell Culture Products  
     ELISAs   Flow Cytometry Kits  
     Primer Pairs   Kinase Activity Assays/Reagents  
     ELISpot Kits/Development Modules   TFB/Immunoprecipitation Assays  
     Apoptosis Detection Kits/Reagents   Protease Activity Assays/Reagents  
     DNA Damage/Repair Kits/Reagents   Multiplex/Array Assay Kits/Reagents  
     Cell Selection/Detection Kits/Reagents   ELISA/Assay Development Kits/Reagents  
     Phosphatase Activity Assays/Reagents   Recombinant/Natural Proteins for CA10 (Carbonic Anhydrase X/CA10)  
     Tagged/untagged cDNA clones
     Validated SYBR primer pairs
     Purified proteins from HEK293T cells
     Lysates
     Western blot validated antibodies
     shRNA in GFP-retroviral vector
     siRNA
     Custom Immunoassay Development
     Fluorogenic Cell Assay Kits
     miRNA Primers for qPCR Assays
     3' UTR Clones for miRNA Target Studies
     miRNA Expression Plasmids

         		 
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of CA10
     SeqTarget long-range PCR primers for resequencing CA10
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for CA10
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of CA10
     GenScript Custom Purified and Recombinant Proteins Services for CA10 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for CA10
     GenScript Custom Assay Services for CA10 GenScript Custom Superior Antibodies Services for CA10
     GenScript Custom overexpressing Cell Line Services for CA10 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in CA10 promoter
     Search Chromatin IP Primers for CA10
     RT2 qPCR Primer Assay for CA10
     Search GNC Networks for CA10
     Assays for microRNAs that regulate CA10
     SABiosciences Custom PCR Arrays for CA10
     Search Tocris compounds for CA10
     Proteins and Antibodies for CA10
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     Antibodies for CA10
     Proteins for CA10
     Lysates for CA10
     Browse antibodies at Epitomics
     Browse ProSpec Recombinant Proteins

     ELISAs and CLIAs for CA10
           

    GeneCards Homepage - Last full update: 31 Dec 2010 - Incremental updates: 9 Jan 2011 , 10 Jan 2011

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