Aliases &
Descriptions
for CCDC112 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| coiled-coil domain containing 1121 2 | | mutated in bladder cancer 12 | | MGC396331 2 | | OTTHUMP000002229132 | | Mutated in bladder cancer protein 12 3 | | coiled-coil domain-containing protein 1122 | | MBC12 3 | | OTTHUMP000002229142 |
Export aliases for CCDC112 gene to outside databasesPrevious GC identifers: GC05M114630 GC05M114602 |
Summaries
for CCDC112 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for CCDC112 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CCDC112 gene promoter:
Pax-6 FOXO3b FOXO3a FOXJ2 (long isoform) AREB6 RORalpha1 FOXI1 HSF1 (long) HSF2 RFX1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CCDC112
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for CCDC112  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q22.3 Ensembl cytogenetic band: 5q22.3 HGNC cytogenetic band: 5q22.3CCDC112 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05M109785: view genomic region
(about GC identifiers)
Start:
|
109,785,258 bp from pter |
End:
|
109,814,831 bp from pter |
Size:
|
29,574 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr5- 114,602,885-114,632,528 |
RefSeq DNA sequence:- NC_000005.9 NT_034772.6
|
Proteins
for CCDC112 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: CC112_HUMAN, Q8NEF3 (See
protein sequence)Recommended Name: Coiled-coil domain-containing protein 112 Size: 446 amino acids; 53565 Da
Secondary accessions: Q6A334Alternative splicing: 2 isoforms: Q8NEF3-1 Q8NEF3-2 Explore the universe of human proteins at neXtProt for CCDC112: NX_Q8NEF3
Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins (2 alternative transcripts):
NP_001035530.1 NP_689762.2
ENSEMBL proteins: ENSP00000368931 ENSP00000424876 ENSP00000378925 ENSP00000296647 ENSP00000423712
Human Recombinant Proteins
Antibodies for CCDC112:
Assays for CCDC112: |
Protein
Domains/
Families
for CCDC112 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q8NEF3 |
Gene Function
for CCDC112 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
1 Gene Ontology (GO) molecular function term (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000166 | nucleotide binding |
-- | -- |
About this table
CCDC112 for ontologies About GeneDecksing
|
Pathways & Interactions
for CCDC112 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for CCDC112
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CCDC112
2 Interacting proteins for CCDC112 (Q8NEF32) via UniProtKB, MINT, and/or STRINGAbout this table
|
Drugs & Compounds
for CCDC112 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for CCDC112
|
Transcripts
for CCDC112 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for CCDC112 gene (2 alternative transcripts): NM_001040440.2 NM_152549.2 Additional cDNA sequence: AJ580807.1 AK307327.1 BC031242.1 CR604116.1 5 DOTS entries: DT.99992471 DT.109704 DT.99963946 DT.120844428 DT.86852007 24/74 AceView cDNA sequences (see all 74): BQ029037 CR604116 BM874684 NM_152549 AW160841 BU950252 BM676359 CB306814 BM874339 AA357020 BM873516 BM975079 BG680569 BC031242 BM920778 BU678651 BP431930 AW161283 CB409979 BM873447 CB159927 CD107888 CB134654 AW196877
 highest scoring ESTs for CCDC112:BI458748 AA227689 AA855011 AI619774 AI652029 AI983755 AW160841 AW161283 AW196877 BC031242 Unigene Cluster for CCDC112: Coiled-coil domain containing 112 Hs.436121 [show with all ESTs]Unigene Representative Sequence: NM_152549
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for CCDC112
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10 |
|---|
|
| SP1: | | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP2: | | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for CCDC112
8 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000503027 ENST00000379611 ENST00000502975 ENST00000506442 ENST00000513730
ENST00000395557 ENST00000296647(uc003kqy.2 uc003kqz.2 uc003kra.2)
ENST00000512261
|
Expression
for CCDC112 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| CCDC112 expression in normal and diseased human tissues
1 / 2 / 3 3 probe-sets matching CCDC112 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 56805_at2, 3
|
U95-C |
1 |
0.81 |
1.00 |
1.00 |
1.00 |
N52761 |
0.60 |
1.00 |
0.82 |
1 |
| 235208_at2, 3
|
U133-B |
1 |
0.36 |
1.00 |
-- |
-- |
AW157712 |
0.40 |
1.00 |
0.76 |
1 |
| 235208_at2
|
U133Plus2 |
1 |
0.36 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
CCDC112 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: CTTTGTTTTA
SOURCE GeneReport for Unigene cluster: Hs.436121
SABiosciences Custom PCR Arrays for CCDC112
|
Orthologs
for CCDC112 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for CCDC112 gene from 5/8 species (see all 8)
About this table Species with no ortholog for CCDC112
ENSEMBL Gene Tree for CCDC112 (if available) |
Paralogs
for CCDC112 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| -- |
Genomic Variants
for CCDC112 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 5 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for CCDC112 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for CCDC112
1 CNV: 4473 | | QIAGEN SeqTarget long-range PCR primers for resequencing CCDC112 |
|
Disorders & Mutations
for CCDC112 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Medical News
for CCDC112 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for CCDC112 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
7 PubMed articles for CCDC112 gene integrated from 7 sources:
(articles sorted by number of sources associating them with CCDC112)- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
- Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
- Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
|
External Searches for CCDC112 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CCDC112 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CCDC112 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CCDC112 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for CCDC112 gene:
Search GeneIP for patents involving CCDC112
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CCDC112 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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