Aliases &
Descriptions
for CCDC64 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| coiled-coil domain containing 641 2 | | H_267D11.12 | | FLJ264501 2 | | bicaudal D-related protein 12 | | Coiled-coil domain-containing protein 64A2 3 | | WUGSC:H_267D11.12 | | BICDR-12 3 | | BICDR13 | | BICD-related protein 12 3 | | |
Export aliases for CCDC64 gene to outside databasesPrevious GC identifers: GC12P118891 GC12P120427 |
Summaries
for CCDC64 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: BICR1_HUMAN, Q6ZP65Function: Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth.Regulates the secretory vesicle transport by controlling the accumulation of Rab6-containing secretory vesicles in thepericentrosomal region restricting anterograde secretory transport during the early phase of neuronal differentiation,thereby inhibiting neuritogenesis (By similarity)
|
Genomic Views
for CCDC64 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CCDC64 gene promoter:
RORalpha2 MyoD FOXO4 Bach2 MEF-2A FOXO1a FOXO3b FOXO3a Arnt AREB6
Other transcription factors
Search SABiosciences Chromatin IP Primers for CCDC64
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for CCDC64  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q24.23 Ensembl cytogenetic band: 12q24.23 HGNC cytogenetic band: 12q24.23CCDC64 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12P117436: view genomic region
(about GC identifiers)
Start:
|
117,436,813 bp from pter |
End:
|
117,541,410 bp from pter |
Size:
|
104,598 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr12+ 120,427,648-120,532,299 |
RefSeq DNA sequence:- NC_000012.11 NT_009775.17
|
Proteins
for CCDC64 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: BICR1_HUMAN, Q6ZP65 (See
protein sequence)Recommended Name: Bicaudal D-related protein 1 Size: 573 amino acids; 64841 Da
Subunit: Interacts with KIF1C. Interacts with RAB6A and RAB6B; interaction is specific to Rab6 (By similarity)
Subcellular location: Cytoplasm, cytoskeleton, centrosome (By similarity). Note=Localizes around the centrosome (Bysimilarity)
Sequence caution: Sequence=AAC83181.1; Type=Erroneous gene model prediction; Sequence=BAC85259.1; Type=Miscellaneousdiscrepancy; Note=Aberrant splicing;
Secondary accessions: O95000Explore the universe of human proteins at neXtProt for CCDC64: NX_Q6ZP65
Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_997194.2
ENSEMBL proteins: ENSP00000257583 ENSP00000380690 ENSP00000349605 ENSP00000399658
Human Recombinant Proteins
3 Gene Ontology (GO) cellular component terms (GO ID links to tree view): About this table
CCDC64 for ontologies About GeneDecksing
Antibodies for CCDC64:
Assays for CCDC64: |
Protein
Domains/
Families
for CCDC64 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q6ZP65 UniProtKB/Swiss-Prot: BICR1_HUMAN, Q6ZP65Similarity: Belongs to the BICDR family |
Gene Function
for CCDC64 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
UniProtKB/Swiss-Prot: BICR1_HUMAN, Q6ZP65Function: Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth.Regulates the secretory vesicle transport by controlling the accumulation of Rab6-containing secretory vesicles in thepericentrosomal region restricting anterograde secretory transport during the early phase of neuronal differentiation,thereby inhibiting neuritogenesis (By similarity)
2 Gene Ontology (GO) molecular function terms (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0017137 | Rab GTPase binding |
ISS | -- | | GO:0034452 | dynactin binding |
ISS | -- |
About this table
CCDC64 for ontologies About GeneDecksing
|
Pathways & Interactions
for CCDC64 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for CCDC64
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CCDC64
4 Gene Ontology (GO) biological process terms (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006810 | transport |
IEA | -- | | GO:0007399 | nervous system development |
IEA | -- | | GO:0031175 | neuron projection development |
ISS | -- | | GO:0055107 | Golgi to secretory granule transport |
ISS | -- |
About this table
CCDC64 for ontologies About GeneDecksing
|
Drugs & Compounds
for CCDC64 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for CCDC64
|
Transcripts
for CCDC64 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for CCDC64 gene: NM_207311.2 Additional cDNA sequence: AK129960.1 AK297888.1 AK301580.1 U88834.1 10 DOTS entries: DT.310685 DT.97838857 DT.91654657 DT.91852319 DT.92016854 DT.121172536 DT.121172643 DT.97783689 DT.97796495 DT.99979023 24/84 AceView cDNA sequences (see all 84): AI627924 AA410903 BI761571 BX951980 BQ882213 CK299198 BE891474 BX102169 BM759392 Z43729 AI878856 AK129960 NM_207311 AI567681 BM458771 BQ637480 BU683970 BQ690977 BU163592 BI907338 BQ882210 BE044642 BX110064 AW152325
 highest scoring ESTs for CCDC64:AA394183 AA416985 AA477629 AA594135 AI003323 AI207000 AI249708 AI271678 AI473206 AI567681 Unigene Cluster for CCDC64: Coiled-coil domain containing 64 Hs.369763 [show with all ESTs]Unigene Representative Sequence: NM_207311
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for CCDC64 (see all 7)
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c | ^ | 9a | · | 9b | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | · | 13c | · | 13d |
|---|
|
| SP1: | | | | | | | - | | | | | | | | | | | | | | - | | - | | - | | - | | - | | | | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | - | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | - | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for CCDC64
4 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000257583(uc001txk.2 uc001txl.1 uc009zwv.1 uc010sze.1 uc010szf.1)
ENST00000397558 ENST00000357093 ENST00000446727
|
Expression
for CCDC64 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| CCDC64 expression in normal and diseased human tissues
1 / 2 / 3 6 probe-sets matching CCDC64 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 32881_at2, 3
|
U95-A |
1 |
0.69 |
1.00 |
0.72 |
0.97 |
U88834 |
0.80 |
0.80 |
0.80 |
1 |
| 43988_at2, 3
|
U95-B |
1 |
0.38 |
1.00 |
0.97 |
1.06 |
AI760224 |
0.80 |
1.00 |
0.91 |
1 |
| 215015_at2, 3
|
U133-A |
1 |
0.82 |
1.00 |
-- |
-- |
AA319460 |
0.60 |
1.00 |
0.82 |
1 |
| 228320_x_at2, 3
|
U133-B |
1 |
0.64 |
1.00 |
-- |
-- |
R61322 |
0.80 |
1.00 |
0.91 |
1 |
| 215015_at2
|
U133Plus2 |
1 |
0.82 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 228320_x_at2
|
U133Plus2 |
1 |
0.64 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
CCDC64 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: TATGGATTTT
SOURCE GeneReport for Unigene cluster: Hs.369763
SABiosciences Custom PCR Arrays for CCDC64
|
Orthologs
for CCDC64 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for CCDC64 gene from 5/7 species (see all 7)
About this table Species with no ortholog for CCDC64
ENSEMBL Gene Tree for CCDC64 (if available) |
Paralogs
for CCDC64 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for CCDC64 gene
- CCDC64B2
CCDC64 for paralogs About GeneDecksing
|
Genomic Variants
for CCDC64 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 12 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for CCDC64 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for CCDC64
2 CNVs: 35050 71597
1 Inversion: 37131 | | QIAGEN SeqTarget long-range PCR primers for resequencing CCDC64 |
|
Disorders & Mutations
for CCDC64 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CCDC64 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: CCDC64 (1 document)
Export disorders and mutations for CCDC64 gene to outside databases
|
Medical News
for CCDC64 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for CCDC64 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
4 PubMed articles for CCDC64 gene integrated from 7 sources:
(articles sorted by number of sources associating them with CCDC64)- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- A genome-wide study of common SNPs and CNVs in cognit ive performance in the CANTAB. (PubMed id 19734545)1 Need A.C....Goldstein D.B. (2009)
- The finished DNA sequence of human chromosome 12. (PubMed id 16541075)2 Scherer S.E.... Gibbs R.A. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
|
External Searches for CCDC64 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CCDC64 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CCDC64 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CCDC64 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for CCDC64 gene:
Search GeneIP for patents involving CCDC64
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CCDC64 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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| |  | Search Tocris compounds for CCDC64 |
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