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CDK16 Gene

protein-coding   GIFtS: 52

GC0XP044787
cyclin-dependent kinase 16
(Previous name: PCTAIRE protein kinase 1 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: PCTK1)
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
cyclin-dependent kinase 161 2     Serine/threonine-protein kinase PCTAIRE-12 3
PCTK12 3 5     PCTAIRE-motif protein kinase 12 3
PCTGAIRE1 2     PCTAIRE protein kinase 11
PCTAIRE1 2     cell division protein kinase 162
PCTAIRE11 2     EC 2.7.11.223
FLJ166651 2     

External Ids:    HGNC: 87491   Entrez Gene: 51272   Ensembl: ENSG000001022257   UniProtKB: Q005363   

Export aliases for CDK16 gene to outside databases

Previous GC identifers: GC0XP046963 GC0XP047078


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CDK16:
The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may
play a role in signal transduction cascades in terminally differentiated cells; in exocytosis; and in transport of
secretory cargo from the endoplasmic reticulum. This gene is thought to escape X inactivation. Alternative splicing
results in multiple transcript variants encoding different isoforms. (provided by RefSeq)

UniProtKB/Swiss-Prot: CDK16_HUMAN, Q00536
Function: May play a role in signal transduction cascades in terminally differentiated cells

Gene Wiki entry for CDK16 (PCTK1)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for CDK16
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for CDK16

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for CDK16 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp11   Ensembl cytogenetic band:  Xp11.23   HGNC cytogenetic band: Xp11

CDK16 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CDK16 gene location

GeneLoc gene densities for chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP044787:  view genomic region     (about GC identifiers)

Start:
44,787,880 bp from pter
End:
44,799,166 bp from pter
Size:
11,287 bases
Orientation:
plus strand

1 alternative location:
ChrX+ 47,077,259-47,089,396     
RefSeq DNA sequence:
NC_000023.10  NT_079573.4  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: CDK16_HUMAN, Q00536 (See protein sequence)
Recommended Name: Cell division protein kinase 16  
Size: 496 amino acids; 55716 Da
Subunit: Found in a complex containing CABLES1, CDK17 and TDRD7. Interacts with YWHAH, YWHAQ and YWHAZ (By similarity)
PDB structures from and Proteopedia :
3MTL (3D)    
Secondary accessions: A8K280

Explore the universe of human proteins at neXtProt for CDK16: NX_Q00536 

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins (3 alternative transcripts): 
    NP_001163931.1  NP_006192.1  NP_148978.2  


    ENSEMBL proteins: 
    ENSP00000430988 ENSP00000429044 ENSP00000349762 ENSP00000428351 ENSP00000431085 ENSP00000429985 
    ENSP00000276052 ENSP00000429259 ENSP00000430824 ENSP00000430486 ENSP00000430966 ENSP00000405798 
    ENSP00000428349 ENSP00000429751 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: CDK16
    OriGene Protein Over-expression Lysate: CDK16
    GenScript Custom Purified and Recombinant Proteins Services for CDK16 
    Novus Biologicals Proteins for CDK16
    Novus Biologicals Lysates for CDK16
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins


    Antibodies for CDK16: 
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for CDK16
    Browse R&D Systems for Antibodies
    Cell Signaling Technology (CST) Antibodies for CDK16  (Pctaire1)
    Browse OriGene Antibodies
    GenScript Custom Superior Antibodies Services for CDK16 
    Novus Biologicals Antibodies for CDK16
    Browse antibodies at Epitomics

    Assays for CDK16: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CDK16 
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for CDK16 


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    CDK16 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR017441 Protein_kinase_ATP_BS
     IPR002290 Ser/Thr_prot_kinase_dom
     IPR011009 Kinase-like_dom
     IPR008271 Ser/Thr_prot_kinase_AS
     IPR000719 Prot_kinase_cat_dom

    Graphical View of Domain Structure for InterPro Entry Q00536

    ProtoNet protein and cluster: Q00536

    UniProtKB/Swiss-Prot: CDK16_HUMAN, Q00536
    Similarity: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily
    Similarity: Contains 1 protein kinase domain


    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    UniProtKB/Swiss-Prot: CDK16_HUMAN, Q00536
    Function: May play a role in signal transduction cascades in terminally differentiated cells
    Catalytic activity: ATP + a protein = ADP + a phosphoprotein
    Enzyme Number (IUBMB): EC 2.7.11.22 

    Inhib.
    RNA:
        
    Browse for Gene Knock-down Tools from Millipore
    Sigma-Aldrich Nano Scale siRNA for CDK16
    Sigma-Aldrich siRNA Panels and esiRNA and siRNA for CDK16
    Sigma-Aldrich shRNA Panels and shRNA for CDK16
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 4): CDK16
    OriGene shRNA RFP (see all 4): CDK16
    OriGene basic RS shRNA (see all 4): CDK16
    OriGene siRNA (see all 4): CDK16
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of CDK16 
    miRNA:Sigma-Aldrich microRNA Mimics for CDK16
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of CDK16 
    Search SABiosciences for Assays for microRNAs that regulate CDK16

    Gene
    Editing:
    Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): CDK16
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 4): CDK16
    OriGene untagged cDNA clones in CMV expression vector (see all 4): CDK16
    OriGene 3'-UTR clone (see all 2): CDK16 
    Browse MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for CDK16 
    Sino Biological Human cDNA Clone for CDK16

    Cell
    Lines:
      
    GenScript Custom overexpressing Cell Line Services for CDK16 

    5/7 Gene Ontology (GO) molecular function terms (GO ID links to tree view) (see all 7):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166 nucleotide binding IEA--
    GO:0004672 protein kinase activity NAS1437147
    GO:0004674 protein serine/threonine kinase activity TAS1437147
    GO:0004693 cyclin-dependent protein kinase activity IEA--
    GO:0005515 protein binding IPI16091426
    About this table

    CDK16 for ontologies           About GeneDecksing

    Animal Models: 1 MGI phenotypic allele for Cdk16 (no phenotypes)


    CDK16 for phenotypes           About GeneDecksing


    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section


    CDK16 for pathways           About GeneDecksing

    1 Millipore Pathway for CDK16
        Signal transduction PKA signaling

        SABiosciences Custom Pathway-Focused PCR Arrays for CDK16 

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CDK16

    2 Interacting proteins for CDK16 (Q005361, 2) via UniProtKB, MINT, and/or STRING
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SEC23AQ154361EBI-726261,EBI-81088
    YWHAZP631042MINT-8006109
    About this table

    1 Gene Ontology (GO) biological process term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468 protein phosphorylation IEA--
    About this table

    CDK16 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section
    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CDK16


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section

    Inhib.
    RNA:
         
    Browse for Gene Knock-down Tools from Millipore
    Sigma-Aldrich Nano Scale siRNA for CDK16
    Sigma-Aldrich siRNA Panels and esiRNA and siRNA for CDK16
    Sigma-Aldrich shRNA Panels and shRNA for CDK16
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 4): CDK16
    OriGene shRNA RFP (see all 4): CDK16
    OriGene basic RS shRNA (see all 4): CDK16
    OriGene siRNA (see all 4): CDK16
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of CDK16 
    miRNA: Sigma-Aldrich microRNA Mimics for CDK16
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of CDK16 
    Search SABiosciences for Assays for microRNAs that regulate CDK16
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): CDK16
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 4): CDK16
    OriGene untagged cDNA clones in CMV expression vector (see all 4): CDK16
    OriGene 3'-UTR Clone (see all 2): CDK16 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for CDK16 
    Primers: OriGene genome-wide validated SYBR primer pairs: CDK16
    Browse OriGene validated miRNA SYBR primer pairs 
    Search SABiosciences RT2 qPCR Primer Assays for CDK16

    REFSEQ mRNAs for CDK16 gene (3 alternative transcripts): 

    NM_001170460.1  NM_006201.4  NM_033018.3  

    Additional cDNA sequence: 

    AB209465.1 AK096881.1 AK290145.1 AK301832.1 AK303849.1 BC001048.2 BC006190.2 BC009852.2 
    BC015607.2 BT006827.1 CR612039.1 CR620813.1 X66363.1 

    24/29 DOTS entries (see all 29):

    DT.100058938  DT.100640965  DT.95110942  DT.443184  DT.100818191  DT.99983136  DT.100818193  DT.100818189 
    DT.95076636  DT.97862739  DT.121295829  DT.95263149  DT.100818182  DT.121295863  DT.91798196  DT.95208593 
    DT.100731789  DT.121295816  DT.121295817  DT.121295845  DT.121295856  DT.121295865  DT.40220735  DT.91773109 

    24/464 AceView cDNA sequences (see all 464):

    F17521 BI964065 CB306800 H14264 AI144457 BU859301 AK131486 AI917446 
    BU184870 CN483617 AI051719 BM264559 BM973729 H02429 AI338323 BG490494 
    BQ945864 BC006190 AW241196 CA433645 BQ012947 CK903784 BI062181 BQ185403 

    Unigene Cluster for CDK16:

    Cyclin-dependent kinase 16
    Hs.496068  [show with all ESTs]
    Unigene Representative Sequence: AB209465


    GeneLoc Exon Structure

    5/21 Alternative Splicing Database (ASD) splice patterns (SP) for CDK16 (see all 21)

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c · 3d ^ 4a · 4b · 4c · 4d · 4e ^ 5a · 5b · 5c · 5d · 5e · 5f ^ 6a · 6b · 6c ^ 7a · 7b · 7c ^ 8 ^ 9a ·
    SP1:                                            -     -     -     -     -     -     -     -     -     -     -     -     -                             -         
    SP2:                                                                          -     -     -     -     -     -     -     -                             -         
    SP3:                                                                                                                                                  -         
    SP4:                                                                                                                                                  -         
    SP5:                                                                                                                                                            

    ExUns: 9b ^ 10 ^ 11 ^ 12a · 12b · 12c ^ 13a · 13b ^ 14 ^ 15a · 15b ^ 16 ^ 17a · 17b ^ 18a · 18b ^ 19a · 19b ^ 20a · 20b ^ 21a · 21b ^ 22a · 22b ^ 23a · 23b ·
    SP1:                                                        -                                         -                 -     -                                 
    SP2:                                                        -                                         -                 -     -                                 
    SP3:                                                                                                  -                 -     -                                 
    SP4:                                                                                                                    -     -                                 
    SP5:                                                        -                                                           -     -                                 

    About this scheme

    ECgene alternative splicing isoforms for CDK16
    18/22 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 22):
    ENST00000517997 ENST00000523699 ENST00000520141 ENST00000518391 ENST00000357227(uc004dho.2 uc011mlk.1)
    ENST00000520893 ENST00000493213 ENST00000522234 ENST00000522883 ENST00000462483
    ENST00000517426 ENST00000428400(uc011mlj.1) ENST00000276052 ENST00000519758
    ENST00000523543 ENST00000462827 ENST00000523034 ENST00000520295

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    CDK16 expression in normal and diseased human tissues

    1  / 2

    9 probe-sets matching CDK16 gene

    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    39183_at2 U95-A 1 1.00 1.00 0.98 0.99 -- -- -- -- --
    1225_g_at2 U95-A 1 1.00 1.00 0.98 1.07 -- -- -- -- --
    1224_at2 U95-A 1 1.00 1.00 1.00 0.94 -- -- -- -- --
    207239_s_at2 U133-A 1 1.00 1.00 -- -- -- -- -- -- --
    208824_x_at2 U133-A 1 1.00 1.00 -- -- -- -- -- -- --
    208823_s_at2 U133-A 1 1.00 1.00 -- -- -- -- -- -- --
    207239_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    208824_x_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    208823_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    About this table

    CDK16 for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    CDK16 gene expression
    CDK16 gene electronic northern expression
    CDK16 gene sage expression
    About these images

    CGAP SAGE TAG: CCACAGCCAC

    SOURCE GeneReport for Unigene cluster: Hs.496068
    Primers: OriGene genome-wide validated SYBR primer pairs: CDK16
    Browse OriGene validated miRNA SYBR primer pairs 
    Search SABiosciences RT2 qPCR Primer Assays for CDK16
        SABiosciences Custom PCR Arrays for CDK16 


    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section

    Orthologs for CDK16 gene from 5/7 species (see all 7)
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    PCTK11   -- PCTAIRE protein kinase 1 94.22(n)
    98.39(a)
    480897  XM_538015.2  XP_538015.2 
    chimpanzee
    (Pan troglodytes)
    PCTK11   -- PCTAIRE protein kinase 1 99.72(n)
    100(a)
    465602  XM_521035.2  XP_521035.2 
    cow
    (Bos taurus)
    PCTK11   -- PCTAIRE protein kinase 1 94.89(n)
    97.98(a)
    613810  XM_874826.2  XP_879919.1 
    rat
    (Rattus norvegicus)
    Pctk11   -- PCTAIRE protein kinase 1 91.6(n)
    97.58(a)
    81741  NM_001004132.1  NP_001004132.1 
    mouse
    (Mus musculus)
    Cdk165
    Pctk11
    X (16.18 cM)5
    cyclin-dependent kinase 165
    PCTAIRE-motif protein kinase 11
    91.87(n)1
    97.58(a)1
    185551  NM_011049.31  NP_035179.11 
     AI3270595  AK0514255  (see all 40)
    About this table        Species with no ortholog for CDK16

    ENSEMBL Gene Tree for CDK16 (if available)

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
    Paralogs for CDK16 gene
    CDK32  CDK182  CDK142  CDK52  CDK22  CDK172  CDK152  CDK12  

    CDK16 for paralogs           About GeneDecksing



    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/55 NCBI SNPs in CDK16 are shown (see all 55)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr X posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ----------
    rs106171,2
    C47088646(+) TTTTTG/TTTTGT 4 -- ut311Minor allele frequency- T:0.00MN 184
    rs10584651,2
    C,F47088155(+) GTGGAC/AACCGA 8 /E /D mis1 ref11Minor allele frequency- A:0.00MN 184
    rs10585131,2
    --47088316(+) CCAAAC/AACCCC 4 -- ut31 ese31Minor allele frequency- A:0.00MN 184
    rs11360001,2
    --47086867(+) CCTGAA/CACTAC 12 E D fra1 ref10--------
    rs22732721,2
    C,F47083186(-) CCATAT/CGGGAG 3 -- int14Minor allele frequency- C:0.01NS EA 418
    rs59023861,2
    --47086681(+) AGGGA-/CCCCCC 3 -- int1 trp30--------
    rs59063571,2
    C,H,47080994(+) CCTCCC/ACTACT 3 -- ng51 int16Minor allele frequency- A:0.00NA WA 10
    rs59063581,2
    C47086054(+) GCCCCC/TTGACA 8 P L ref1 mis1 ese34Minor allele frequency- T:0.00NS EA 404
    rs59524221,2
    C,F,A47084037(+) CTATCA/GCTACC 8 S ref1 syn1 ese310Minor allele frequency- G:0.08NS EA NA 819
    rs59530131,2
    C47080799(+) CTGAGA/CCCCCC 3 -- int1 ng510--------
    About this table

    HapMap Linkage Disequilibrium images for CDK16 (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 5 variations for CDK16
         5 Indels: 96636 83489 83487 96635 83488

    QIAGEN SeqTarget long-range PCR primers for resequencing CDK16 

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    CDK16 for disorders           About GeneDecksing

    OMIM: 311550

    Locus Specific Mutation Databases (LSDB): CDK16

    Export disorders and mutations for CDK16 gene to outside databases

    (Possibly Related Articles in Doctor's Guide)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/34 PubMed articles for CDK16 gene, integrated from 7 sources (see all 34):
    (articles sorted by number of sources associating them with CDK16)
    1. Cyclin-dependent kinases: a family portrait. (PubMed id 19884882)1, 3 Malumbres M....Wolgemuth D.J. (2009)
    2. Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry. (PubMed id 17192257)1, 2 Wissing J.... Daub H. (2007)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    4. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase gene family. (PubMed id 1437147)1, 3 Okuda T....Downing J.R. (1992)
    8. A family of human cdc2-related protein kinases. (PubMed id 1639063)1, 2 Meyerson M.... Tsai L.-H. (1992)
    9. Regulation of the CDK-related protein kinase PCTAIRE-1 and its possible role in neurite outgrowth in Neuro-2A cells. (PubMed id 12154078)1, 7 Graeser R....Hunt T. (2002)
    10. X inactivation analysis and DNA methylation studies of the ubiquitin activating enzyme E1 and PCTAIRE-1 genes in human and mouse. (PubMed id 8852665)1, 7 Carrel L....Willard H.F. (1996)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 5127 HGNC: 8749 AceView: PCTK1 Ensembl:ENSG00000102225 euGenes: HUgn5127
    ECgene: CDK16 H-InvDB: CDK16

    (According to HUGE)
    About This Section
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    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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    (Patent information from GeneIP,
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    Patent Information for CDK16 gene:
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