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CTBS Gene

protein-coding   GIFtS: 52

GC01M083128
chitobiase, di-N-acetyl-
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: CTB)
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
chitobiase, di-N-acetyl-1 2
CTB2 3 5
OTTHUMP000000115702
di-N-acetylchitobiase2
EC 3.2.1.-3

External Ids:    HGNC: 24961   Entrez Gene: 14862   Ensembl: ENSG000001171517   UniProtKB: Q014593   

Export aliases for CTBS gene to outside databases

Previous GC identifers: GC01P085516 GC01M084156 GC01M084307 GC01M084442 GC01M084732 GC01M085018


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CTBS:
Chitobiase is a lysosomal glycosidase involved in degradation of asparagine-linked oligosaccharides on glycoproteins
(Aronson and Kuranda, 1989 (PubMed 2531691)).(supplied by OMIM)

UniProtKB/Swiss-Prot: DIAC_HUMAN, Q01459
Function: Involved in the degradation of asparagine-linked glycoproteins. Hydrolyze of N-acetyl-beta-D-glucosamine
(1-4)N-acetylglucosamine chitobiose core from the reducing end of the bond, it requires prior cleavage by
glycosylasparaginase

Gene Wiki entry for CTBS

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CTBS gene promoter:
         NF-kappaB   NF-kappaB1   LCR-F1   POU3F2   RORalpha1   GCNF-2   GCNF-1   SREBP-1c   SREBP-1b   SREBP-1a   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for CTBS

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for CTBS 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p22   Ensembl cytogenetic band:  1p22.3   HGNC cytogenetic band: 1p22

CTBS Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CTBS gene location

GeneLoc gene densities for chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M083128:  view genomic region     (about GC identifiers)

Start:
83,128,864 bp from pter
End:
83,150,219 bp from pter
Size:
21,356 bases
Orientation:
minus strand

1 alternative location:
Chr1- 85,018,804-85,040,163     
RefSeq DNA sequence:
NC_000001.10  NT_032977.9  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: DIAC_HUMAN, Q01459 (See protein sequence)
Recommended Name: Di-N-acetylchitobiase precursor  
Size: 385 amino acids; 43760 Da
Subcellular location: Lysosome

Explore the universe of human proteins at neXtProt for CTBS: NX_Q01459 

REFSEQ proteins: NP_004379.1  

ENSEMBL proteins: 
ENSP00000359664 ENSP00000359659 


Human Recombinant Proteins 
Browse Purified and Recombinant Proteins at Millipore
Browse Human Recombinant Proteins at Sigma-Aldrich
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
OriGene Protein Over-expression Lysate: CTBS
GenScript Custom Purified and Recombinant Proteins Services for CTBS 
Novus Biologicals Protein for CTBS
Novus Biologicals Lysate for CTBS
Browse Sino Biological Recombinant Proteins
Browse ProSpec Recombinant Proteins

1 Gene Ontology (GO) cellular component term (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005764 lysosome IEA--
About this table

CTBS for ontologies           About GeneDecksing



Antibodies for CTBS: 
Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Sigma-Aldrich Antibodies for CTBS
R&D Systems Antibodies for CTBS (Chitobiase/CTBS)
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GenScript Custom Superior Antibodies Services for CTBS 
Novus Biologicals Antibodies for CTBS
Browse antibodies at Epitomics

Assays for CTBS: 
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GenScript Custom Assay Services for CTBS 
Browse Enzo Life Sciences for kits & assays
Uscn ELISAs and CLIAs for CTBS 


(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

CTBS for domains           About GeneDecksing

5 InterPro domains/families:
 IPR001579 Glyco_hydro_18_chit_AS
 IPR011583 Chitinase_II
 IPR017853 Glyco_hydro_catalytic_core
 IPR001223 Glyco_hydro18cat
 IPR013781 Glyco_hydro_sg_catalytic

Graphical View of Domain Structure for InterPro Entry Q01459

ProtoNet protein and cluster: Q01459

1 Blocks protein family: IPB001579 Glycoside hydrolase

UniProtKB/Swiss-Prot: DIAC_HUMAN, Q01459
Similarity: Belongs to the glycosyl hydrolase 18 family


(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: DIAC_HUMAN, Q01459
Function: Involved in the degradation of asparagine-linked glycoproteins. Hydrolyze of N-acetyl-beta-D-glucosamine
(1-4)N-acetylglucosamine chitobiose core from the reducing end of the bond, it requires prior cleavage by
glycosylasparaginase
Enzyme Number (IUBMB): EC 3.2.1.- 

Inhib.
RNA:
    
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich esiRNA and siRNA for CTBS
Sigma-Aldrich shRNA for CTBS
OriGene 29mer shRNA kits in GFP-retroviral vector: CTBS
OriGene shRNA RFP: CTBS
OriGene basic RS shRNA: CTBS
OriGene siRNA: CTBS
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of CTBS 
miRNA:Sigma-Aldrich microRNA Mimics for CTBS
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of CTBS 
Search SABiosciences for Assays for microRNAs that regulate CTBS

Gene
Editing:
Browse CompoZr Knockout ZFN at Sigma-Aldrich 

Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
Browse iPSC Reprogramming Factors at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: CTBS
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: CTBS
OriGene untagged cDNA clones in CMV expression vector: CTBS
OriGene 3'-UTR clone: CTBS 
Browse MicroRNA Expression Plasmids 
GenScript Custom cDNA clone Services for CTBS 
Browse Sino Biological Human cDNA Clones

Cell
Lines:
  
GenScript Custom overexpressing Cell Line Services for CTBS 

Genatlas biochemistry entry for CTBS:
lysosomal chitobiase,involved in degradation of asparagine-linked glycoproteins

3 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds ----
GO:0004568 chitinase activity IEA--
GO:0043169 cation binding IEA--
About this table

CTBS for ontologies           About GeneDecksing


(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section


CTBS for pathways           About GeneDecksing

1 Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Pathway for  CTBS
    Aminosugars Metabolism

    SABiosciences Custom Pathway-Focused PCR Arrays for CTBS 

    Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Molecular Interaction Network for CTBS
    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CTBS

3 Interacting proteins for CTBS (ENSP000003596643) via UniProtKB, MINT, and/or STRING
InteractantInteraction Details
GeneCardExternal ID(s)
HK1ENSP000003486973STRING: ENSP00000348697
HK2ENSP000002905733STRING: ENSP00000290573
HK3ENSP000002924323STRING: ENSP00000292432
About this table

3 Gene Ontology (GO) biological process terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005975 carbohydrate metabolic process IEA--
GO:0006032 chitin catabolic process IEA--
GO:0009313 oligosaccharide catabolic process IEA--
About this table

CTBS for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section
Browse Small Molecules at Sigma-Aldrich
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CTBS


(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib.
RNA:
     
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich esiRNA and siRNA for CTBS
Sigma-Aldrich shRNA for CTBS
OriGene 29mer shRNA kits in GFP-retroviral vector: CTBS
OriGene shRNA RFP: CTBS
OriGene basic RS shRNA: CTBS
OriGene siRNA: CTBS
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of CTBS 
miRNA: Sigma-Aldrich microRNA Mimics for CTBS
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of CTBS 
Search SABiosciences for Assays for microRNAs that regulate CTBS
Clones: Browse FLAG tag genes at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: CTBS
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: CTBS
OriGene untagged cDNA clones in CMV expression vector: CTBS
OriGene 3'-UTR Clone: CTBS 
Browse OriGene MicroRNA Expression Plasmids 
GenScript Custom cDNA clone Services for CTBS 
Primers: OriGene genome-wide validated SYBR primer pairs: CTBS
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for CTBS: PPH12323A

REFSEQ mRNAs for CTBS gene: 

NM_004388.2  

Additional cDNA sequence: 

AK075423.1 AK298703.1 AK314640.1 BC024007.2 BC065191.1 BC096752.1 BC126333.1 BC126335.1 
CR590327.1 CR595959.1 CR602282.1 CR615615.1 M95767.1 

8 DOTS entries:

DT.95172057  DT.410826  DT.95297552  DT.121427673  DT.92443352  DT.100782215  DT.121427721  DT.97795709 

24/423 AceView cDNA sequences (see all 423):

AI911433 BX956979 AW340694 H15938 BI467209 AI368858 BG008942 M95767 
CA425643 AA974553 BX109756 AI499049 AI346848 BM826029 CB121330 BT006823 
AA923637 AI601142 AA878529 CR590327 AA167380 AA371357 CR615615 BF109470 

highest scoring ESTs for CTBS:

M95767 AI269096 AI547276 AK075423 AL530653 BC024007 BC065191 BG703950 BG704290 BG719820 

Unigene Cluster for CTBS:

Chitobiase, di-N-acetyl-
Hs.513557  [show with all ESTs]
Unigene Representative Sequence: NM_004388


GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for CTBS

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c
SP1:        -                                                   
SP2:                                                            
SP3:        -           -                                       
SP4:                    -                                       

About this scheme

ECgene alternative splicing isoforms for CTBS
4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000477677(uc001dkd.2 uc001dkb.2) ENST00000465118 ENST00000370630(uc001dkc.2 uc001dka.2)
ENST00000370625

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

CTBS expression in normal and diseased human tissues

1  / 2  / 3

6 probe-sets matching CTBS gene

Affymetrix
probe-set
Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
37855_at2, 3 U95-A 1 1.00 1.00 0.98 0.97 M95767 1.00 0.90 0.95 1
61307_at2, 3 U95-C 1 0.88 1.00 0.98 1.03 AI547276 0.80 0.88 0.84 1
218923_at2, 3 U133-A 1 1.00 1.00 -- -- AW304174 0.60 0.83 0.73 1
218924_s_at2, 3 U133-A 1 0.91 1.00 -- -- NM_004388 0.60 0.83 0.73 1
218923_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
218924_s_at2 U133Plus2 1 0.91 1.00 -- -- -- -- -- -- --
About this table

CTBS for expression           About GeneDecksing

Data from Genenote  (Publications) and GNF BioGPS
    About these images
CTBS gene expression
CTBS gene electronic northern expression
CTBS gene sage expression
About these images

CGAP SAGE TAG: GAAAGTGGAG

SOURCE GeneReport for Unigene cluster: Hs.513557

Expression variation in blood from EXPOLDB for CTBS

Primers: OriGene genome-wide validated SYBR primer pairs: CTBS
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for CTBS: PPH12323A
    SABiosciences Custom PCR Arrays for CTBS 


(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for CTBS gene from 5/9 species (see all 9)
Organism Gene Locus Description Human
Similarity
NCBI accessions
dog
(Canis familiaris)
CTBS1   -- chitobiase, di-N-acetyl- 84.7(n)
77.31(a)
490188  XM_547309.2  XP_547309.2 
chimpanzee
(Pan troglodytes)
CTBS1   -- chitobiase, di-N-acetyl- 99.21(n)
98.95(a)
456978  XM_513520.2  XP_513520.1 
cow
(Bos taurus)
CTBS1   -- chitobiase, di-N-acetyl- 82.05(n)
71.35(a)
524503  XM_602828.3  XP_602828.3 
rat
(Rattus norvegicus)
Ctbs1   -- chitobiase, di-N-acetyl- 82.45(n)
81.89(a)
81652  NM_031023.1  NP_112285.1 
mouse
(Mus musculus)
Ctbs1 , 5 3 (71.26 cM)5
chitobiase, di-N-acetyl-1, 5 86.58(n)1
86.04(a)1
742451  NM_028836.21  NP_083112.11 
 AK0087915  AV0296325  (see all 9)
About this table        Species with no ortholog for CTBS

ENSEMBL Gene Tree for CTBS (if available)

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
  --

(SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

10/236 NCBI SNPs in CTBS are shown (see all 236)
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidChr 1 posSequenceRecsAA
Chg
TypeMoreRecsAllele
freq
PopTotal
sample
More
----------
rs159111,2
C,F,85029077(+) AGGGAC/TTTTTG 2 I V mis1 ref118Minor allele frequency- T:0.17MN NA EA NS WA 1408
rs10434931,2
C,F,A,H,85020649(-) AGAAAG/AATGAT 1 -- ut3110Minor allele frequency- A:0.10MN NA NS EA WA 788
rs15176021,2
C,F,O,85021557(+) CCTCTA/GAAACC 1 -- int113Minor allele frequency- G:0.13NA NS EA WA 722
rs18032761,2
C,F,A,85020496(-) CATAAA/TGGCAA 1 -- ut31 ese36Minor allele frequency- T:0.09NS EA WA 470
rs18911261,2
C,F,85036538(-) TGGGAC/ACCCTA 1 -- int16Minor allele frequency- A:0.02NS EA NA WA 526
rs23033061,2
C,F,O,A,85036239(+) TGCTGC/GACACA 1 -- int114Minor allele frequency- G:0.25EA NA NS WA 2252
rs23033071,2
C,F,85039955(+) CGGCAG/AAGCTC 2 /L ref1 syn1 ese38Minor allele frequency- A:0.14EA NS NA 2040
rs29115841,2
C,A,85030359(+) GTCTTT/GCCTGA 1 -- int16Minor allele frequency- G:0.02WA NA 60
rs29115871,2
F,85032069(+) TAAAAG/TAATTC 1 -- int14Minor allele frequency- T:0.01NS EA 406
rs29115881,2
C,F,O,A,85034024(+) AGGAGG/AAGAAG 1 -- int1 trp38Minor allele frequency- A:0.32NA EA WA 284
About this table

HapMap Linkage Disequilibrium images for CTBS (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for CTBS: --

QIAGEN SeqTarget long-range PCR primers for resequencing CTBS 

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CTBS for disorders           About GeneDecksing

OMIM: 600873


Export disorders and mutations for CTBS gene to outside databases

(Possibly Related Articles in Doctor's Guide)
About This Section
  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
About This Section

10/11 PubMed articles for CTBS gene, integrated from 7 sources (see all 11):
(articles sorted by number of sources associating them with CTBS)
  1. Lysosomal chitobiase (CTB) and the G-protein gamma 5 subunit (GNG5) genes co-localize to human chromosome 1p22. (PubMed id 7606925)1, 3, 7 Ahmad W....Aronson N.N. (1995)
  2. Structure of the human gene for lysosomal di-N-acetylchitobiase. (PubMed id 10336991)1, 2 Liu B.... Aronson N.N. Jr. (1999)
  3. Characterization of the cDNA and genomic sequence of a G protein gamma subunit (gamma 5). (PubMed id 1549114)1, 3 Fisher K.J. and Aronson N.N. (1992)
  4. Cloning and expression of the cDNA sequence encoding the lysosomal glycosidase di-N-acetylchitobiase. (PubMed id 1527079)1, 2 Fisher K.J. and Aronson N.N. Jr. (1992)
  5. Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. (PubMed id 19159218)2 Chen R.... Zou H. (2009)
  6. Optimum substrate size and specific anomer requirements for the reducing-end glycoside hydrolase di-N-acetylchitobiase. (PubMed id 16794344)1 Aronson N.N. and Halloran B.A. (2006)
  7. A novel dynamin-associating molecule, formin-binding protein 17, induces tubular membrane invaginations and participates in endocytosis. (PubMed id 15252009)1 Kamioka Y....Mochizuki N. (2004)
  8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
  9. N-acetyl beta-D-glucosaminidase is not attached to human sperm membranes through the glycosylphosphatidyl inositol (GPI)-anchor. (PubMed id 11907625)1 Hutchinson T....Pereira B.M. (2002)
  10. Rat liver chitobiase: purification, properties, and role in the lysosomal degradation of Asn-linked glycoproteins. (PubMed id 2751306)1 Aronson N.N....Kuranda M.J. (1989)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 1486 HGNC: 2496 AceView: CTBSandGNG5 Ensembl:ENSG00000117151 euGenes: HUgn1486
ECgene: CTBS H-InvDB: CTBS

(According to HUGE)
About This Section
  --

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
  --

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from XenneX, Inc.)
About This Section
Patent Information for CTBS gene:
Search GeneIP for patents involving CTBS

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
About This Section

 Millipore Custom Antibody & Bulk Services
 Millipore Preclinical / Clinical Development Services
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 Predesigned and custom siRNAs for CTBS Antibodies for CTBS
 Super-pooled esiRNAs for CTBS Browse proteins at Sigma-Aldrich
 Lentivirus-delivered shRNAs for CTBS microRNA Mimics for CTBS
 "Your Favorite Gene" Pathways and Molecular Interaction Networks Browse Nano Scale siRNA at Sigma-Aldrich
 Browse iPSC Reprogramming Factors at Sigma-Aldrich Browse small molecules at Sigma-Aldrich
 Browse FLAG tag genes at Sigma-Aldrich Browse ELISAs at Sigma-Aldrich
 Browse microRNA Target Validation Systems at Sigma-Aldrich Browse CompoZr Knockout ZFN at Sigma-Aldrich
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 Fluorogenic Cell Assay Kits
 miRNA Primers for qPCR Assays
 3' UTR Clones for miRNA Target Studies
 miRNA Expression Plasmids

 
 
 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of CTBS
 SeqTarget long-range PCR primers for resequencing CTBS
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for CTBS
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of CTBS
 GenScript Custom Purified and Recombinant Proteins Services for CTBS GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for CTBS
 GenScript Custom Assay Services for CTBS GenScript Custom Superior Antibodies Services for CTBS
 GenScript Custom overexpressing Cell Line Services for CTBS CloneReady with Over 120,000 Genes
 Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
 Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
 Custom Peptide Services
 Search for Antibodies & Assays

 Regulatory tfbs in CTBS promoter
 Search Chromatin IP Primers for CTBS
 RT2 qPCR Primer Assay for CTBS
 Search GNC Networks for CTBS
 Search for Assays for microRNAs that regulate CTBS
 SABiosciences Custom PCR Arrays for CTBS
 Search Tocris compounds for CTBS
 Browse Sino Biological Proteins and Antibodies
 Browse Sino Biological cDNA Clones
 Antibodies/Proteins Production Services
 Rabbit Monoclonal Antibody Platform
 Bulk Purchasing
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
 Novus Tissue Slides
 Antibodies for CTBS
 Proteins for CTBS
 Lysates for CTBS
 Browse antibodies at Epitomics
 Browse ProSpec Recombinant Proteins

 ELISAs and CLIAs for CTBS
       

GeneCards Homepage - Last full update: 30 Dec 2010 - Incremental updates: 9 Jan 2011 , 10 Jan 2011

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