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CTR9 Gene

protein-coding   GIFtS: 49

GC11P010445
Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
(Previous name: SH2 domain binding protein 1 (tetratricopeptide repeat containing) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: SH2BP1)
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)1 2     TSBP1 2
KIAA01551 2 3 5     SH2 domain-binding protein 12 3
SH2BP12 3 5     p1502 5
SH2 domain binding protein 1 (tetratricopeptide repeat containing)1 2     TPR-containing, SH2-binding phosphoprotein2
p150TSP1 2     RNA polymerase-associated protein CTR9 homolog2

External Ids:    HGNC: 168501   Entrez Gene: 96462   Ensembl: ENSG000001987307   UniProtKB: Q6PD623   

Export aliases for CTR9 gene to outside databases

Previous GC identifers: GC11P010730 GC11P010731 GC11P010772


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CTR9:
CTR9, parafibromin (CDC73; MIM 607393), LEO1 (MIM 610507), and PAF1 (MIM 610506) form the PAF protein complex, which
associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransferase complex
(Rozenblatt-Rosen et al., 2005 (PubMed 15632063)).(supplied by OMIM)

Gene Wiki entry for CTR9

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CTR9 gene promoter:
         GCNF-1   GCNF-2   STAT1   STAT1beta   STAT1alpha   C/EBPalpha   GATA-1   ER-alpha   POU2F1   Sp1   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for CTR9

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for CTR9 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.3   Ensembl cytogenetic band:  11p15.3   HGNC cytogenetic band: 11p15.3

CTR9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CTR9 gene location

GeneLoc gene densities for chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P010445:  view genomic region     (about GC identifiers)

Start:
10,445,613 bp from pter
End:
10,474,231 bp from pter
Size:
28,619 bases
Orientation:
plus strand

1 alternative location:
Chr11+ 10,772,803-10,801,287     
RefSeq DNA sequence:
NC_000011.9  NT_009237.18  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: CTR9_HUMAN, Q6PD62 (See protein sequence)
Recommended Name: RNA polymerase-associated protein CTR9 homolog  
Size: 1173 amino acids; 133502 Da
Subcellular location: Nucleus speckle (By similarity). Note=Found in speckles (By similarity)
Sequence caution: Sequence=BAA09925.2; Type=Erroneous initiation;
Secondary accessions: Q15015

Explore the universe of human proteins at neXtProt for CTR9: NX_Q6PD62 

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_055448.1  

    ENSEMBL proteins: 
    ENSP00000355013 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: CTR9
    GenScript Custom Purified and Recombinant Proteins Services for CTR9 
    Novus Biologicals Lysate for CTR9
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins

    4 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622 intracellular ----
    GO:0005634 nucleus IEA--
    GO:0016593 Cdc73/Paf1 complex IDA16307923
    GO:0016607 nuclear speck IEA--
    About this table

    CTR9 for ontologies           About GeneDecksing



    Antibodies for CTR9: 
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for CTR9
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    GenScript Custom Superior Antibodies Services for CTR9 
    Novus Biologicals Antibodies for CTR9
    Browse antibodies at Epitomics

    Assays for CTR9: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CTR9 
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs and CLIAs at Uscn 


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    CTR9 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR001440 TPR-1
     IPR011990 TPR-like_helical
     IPR013026 TPR-contain
     IPR019734 TPR_repeat

    Graphical View of Domain Structure for InterPro Entry Q6PD62

    ProtoNet protein and cluster: Q6PD62

    UniProtKB/Swiss-Prot: CTR9_HUMAN, Q6PD62
    Similarity: Contains 16 TPR repeats


    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    Inhib.
    RNA:
        
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for CTR9
    Sigma-Aldrich shRNA for CTR9
    OriGene 29mer shRNA kits in GFP-retroviral vector: CTR9
    OriGene shRNA RFP: CTR9
    OriGene basic RS shRNA: CTR9
    OriGene siRNA: CTR9
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of CTR9 
    miRNA:Sigma-Aldrich microRNA Mimics for CTR9
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of CTR9 
    Search SABiosciences for Assays for microRNAs that regulate CTR9

    Gene
    Editing:
    Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: CTR9
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: CTR9
    OriGene untagged cDNA clones in CMV expression vector (see all 2): CTR9
    OriGene 3'-UTR clone: CTR9 
    Browse MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for CTR9 
    Sino Biological Human cDNA Clone for CTR9

    Cell
    Lines:
      
    GenScript Custom overexpressing Cell Line Services for CTR9 

    2 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515 protein binding IPI--
    GO:0042169 SH2 domain binding IEA--
    About this table

    CTR9 for ontologies           About GeneDecksing


    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section

        SABiosciences Custom Pathway-Focused PCR Arrays for CTR9 

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CTR9

    5 Interacting proteins for CTR9 (Q6PD621, 2) via UniProtKB, MINT, and/or STRING
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CDC73Q6P1J91EBI-1019583,EBI-930143
    MLLQ031641EBI-1019583,EBI-591370
    PAF1Q8N7H51EBI-1019583,EBI-2607770
    WDR61Q9GZS31EBI-1019583,EBI-358545
    SMAD9O151982MINT-62121
    About this table

    3 Gene Ontology (GO) biological process terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006396 RNA processing ----
    GO:0010390 histone monoubiquitination IDA16307923
    GO:0033523 histone H2B ubiquitination IDA16307923
    About this table

    CTR9 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section
    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CTR9


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section

    Inhib.
    RNA:
         
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for CTR9
    Sigma-Aldrich shRNA for CTR9
    OriGene 29mer shRNA kits in GFP-retroviral vector: CTR9
    OriGene shRNA RFP: CTR9
    OriGene basic RS shRNA: CTR9
    OriGene siRNA: CTR9
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of CTR9 
    miRNA: Sigma-Aldrich microRNA Mimics for CTR9
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of CTR9 
    Search SABiosciences for Assays for microRNAs that regulate CTR9
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: CTR9
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: CTR9
    OriGene untagged cDNA clones in CMV expression vector (see all 2): CTR9
    OriGene 3'-UTR Clone: CTR9 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for CTR9 
    Primers: OriGene genome-wide validated SYBR primer pairs: CTR9
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for CTR9: PPH13580A

    REFSEQ mRNAs for CTR9 gene: 

    NM_014633.3  

    Additional cDNA sequence: 

    AK291794.1 BC014335.1 BC058914.1 D63875.1 

    13 DOTS entries:

    DT.417534  DT.75192574  DT.100792877  DT.86853284  DT.95206804  DT.101956935  DT.120683957  DT.91753426 
    DT.120683953  DT.65287534  DT.75151646  DT.91828414  DT.91926424 

    24/251 AceView cDNA sequences (see all 251):

    AI478396 AA907605 AI279164 BC014335 AA725733 CA397873 AA883364 AI924726 
    CD370181 AI972468 D63875 AW263693 BM692466 CA306189 BQ722182 BM993861 
    AI302523 AU119376 AA569907 Z36868 AW338994 BM664048 CA434013 BM542829 

    highest scoring ESTs for CTR9:

    D63875 AA083695 AA120987 AA126436 AA133684 AA133685 AA448303 AA599535 AA649176 AA663521 

    Unigene Cluster for CTR9:

    Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
    Hs.725151  [show with all ESTs]
    Unigene Representative Sequence: BC058914


    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for CTR9 (see all 6)

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13a · 13b ^ 14a · 14b · 14c ^ 15 ^ 16a · 16b · 16c · 16d ^ 17 ^ 18 ^ 19 ^
    SP1:                                                                                -           -                                                               
    SP2:                                      -                                                                                                                     
    SP3:                                                                                -           -     -                                                         
    SP4:                                                                                            -                                                               
    SP5:                                                                                                                                                            

    ExUns: 20a · 20b ^ 21 ^ 22a · 22b ^ 23 ^ 24 ^ 25
    SP1:  -                       -                     
    SP2:                                                
    SP3:                                                
    SP4:                                                
    SP5:                                                

    About this scheme

    ECgene alternative splicing isoforms for CTR9
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000361367(uc001mja.2)

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    CTR9 expression in normal and diseased human tissues

    1  / 2  / 3

    3 probe-sets matching CTR9 gene

    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    40844_at2, 3 U95-A 1 0.94 1.00 1.00 1.00 D63875 1.00 1.00 1.00 1
    202060_at2, 3 U133-A 1 1.00 1.00 -- -- NM_014633 0.60 1.00 0.82 1
    202060_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    About this table

    CTR9 for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    CTR9 gene expression
    CTR9 gene electronic northern expression
    CTR9 gene sage expression
    About these images

    CGAP SAGE TAG: GGTCAGATGA

    SOURCE GeneReport for Unigene cluster: Hs.725151

    UniProtKB/Swiss-Prot: CTR9_HUMAN, Q6PD62
    Tissue specificity: Widely expressed

    Primers: OriGene genome-wide validated SYBR primer pairs: CTR9
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for CTR9: PPH13580A
        SABiosciences Custom PCR Arrays for CTR9 


    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section

    Orthologs for CTR9 gene from 5/14 species (see all 14)
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    CTR91   -- Ctr9, Paf1/RNA polymerase II complex component, homolog more 93.38(n)
    98.47(a)
    476853  XM_534056.2  XP_534056.2 
    chimpanzee
    (Pan troglodytes)
    CTR91   -- Ctr9, Paf1/RNA polymerase II complex component, homolog more 99.69(n)
    99.91(a)
    466442  XM_521841.2  XP_521841.2 
    rat
    (Rattus norvegicus)
    Ctr91   -- Ctr9, Paf1/RNA polymerase II complex component, homolog more 89.92(n)
    97.95(a)
    293184  XM_238127.4  XP_238127.4 
    mouse
    (Mus musculus)
    Ctr91 , 5 7 (57.98 cM)5
    Ctr9, Paf1/RNA polymerase II complex component, homolog more1, 5 90.12(n)1
    97.78(a)1
    220831  NM_009431.11  NP_033457.11 
     AA4093365  AB0932115  (see all 27)
    chicken
    (Gallus gallus)
    CTR91   -- Ctr9, Paf1/RNA polymerase II complex component, homolog more 83.49(n)
    95.05(a)
    423035  XM_420968.2  XP_420968.2 
    About this table        Species with no ortholog for CTR9

    ENSEMBL Gene Tree for CTR9 (if available)

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
      --

    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/292 NCBI SNPs in CTR9 are shown (see all 292)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 11 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ----------
    rs66991,2
    C,F,H,10801186(+) AATCAC/GAAATG 1 -- ut31 ese319Minor allele frequency- G:0.21MN EA NA NS WA 1634
    rs9989071,2
    --10792374(-) CCTGGG/TGGCAG 1 -- int10--------
    rs13905761,2
    C,F,A,10774685(+) AAACAC/TTTCCC 1 -- int18Minor allele frequency- T:0.29NA EA WA 466
    rs13905771,2
    H10774716(+) ATTAGG/ATTCTG 1 -- int15Minor allele frequency- A:0.00MN NS EA 556
    rs18116551,2
    C,F,O,A,10789049(+) GTGTGG/TCTATC 1 -- int18Minor allele frequency- T:0.17NA WA 88
    rs18116561,2
    C,F,O,A,10789117(+) GGCCAC/AATGTA 1 -- int114Minor allele frequency- A:0.09MN NS EA NA WA 614
    rs19627101,2
    C,A,H10772114(+) TAATTC/TTTGTA 1 -- ng511Minor allele frequency- T:0.50NA 2
    rs20298911,2
    C,10783885(+) agaaaA/Gagcag 1 -- int17Minor allele frequency- G:0.00NA WA 16
    rs21325151,2
    A10783112(+) TGTTCA/GTGCCA 1 -- int10--------
    rs21325161,2
    10783184(+) ATAAAC/TAAAAA 1 -- int10--------
    About this table

    HapMap Linkage Disequilibrium images for CTR9 (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for CTR9: --

    QIAGEN SeqTarget long-range PCR primers for resequencing CTR9 

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    CTR9 for disorders           About GeneDecksing

    OMIM: 609366

    Human Genome Epidemiology (HuGE) Navigator: CTR9 (1 document)

    Export disorders and mutations for CTR9 gene to outside databases

    (Possibly Related Articles in Doctor's Guide)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/21 PubMed articles for CTR9 gene, integrated from 7 sources (see all 21):
    (articles sorted by number of sources associating them with CTR9)
    1. Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8590280)1, 2, 3 Nagase T....Nomura N. (1995)
    2. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. p150TSP, a conserved nuclear phosphoprotein that contains multiple tetratricopeptide repeats and binds specifically to SH2 domains. (PubMed id 8636124)1, 3 Malek S.N....Desiderio S. (1996)
    6. The PAF complex synergizes with MLL fusion proteins a t HOX loci to promote leukemogenesis. (PubMed id 20541477)1 Muntean A.G....Hess J.L. (2010)
    7. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (2009)
    8. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
    9. SNP combinations in chromosome-wide genes are associated with bone mineral density in Taiwanese women. (PubMed id 18551993)1 Lin G.T....Chang H.W. (2008)
    10. Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment. (PubMed id 19367720)2 Carrascal M.... Abian J. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9646 HGNC: 16850 AceView: SH2BP1 Ensembl:ENSG00000198730 euGenes: HUgn9646
    ECgene: CTR9 H-InvDB: CTR9

    (According to HUGE)
    About This Section
    HUGE: KIAA0155

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
      --

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
    About This Section
    Patent Information for CTR9 gene:
    Search GeneIP for patents involving CTR9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
    Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
    About This Section

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services

     Predesigned and custom siRNAs for CTR9 Antibodies for CTR9
     Super-pooled esiRNAs for CTR9 Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for CTR9 microRNA Mimics for CTR9
     "Your Favorite Gene" Pathways and Molecular Interaction Networks Browse Nano Scale siRNA at Sigma-Aldrich
     Browse iPSC Reprogramming Factors at Sigma-Aldrich Browse small molecules at Sigma-Aldrich
     Browse FLAG tag genes at Sigma-Aldrich Browse ELISAs at Sigma-Aldrich
     Browse microRNA Target Validation Systems at Sigma-Aldrich Browse CompoZr Knockout ZFN at Sigma-Aldrich
    feedback
      
     Antibodies   Cell Culture Products  
     ELISAs   Flow Cytometry Kits  
     Primer Pairs   Kinase Activity Assays/Reagents  
     ELISpot Kits/Development Modules   TFB/Immunoprecipitation Assays  
     Apoptosis Detection Kits/Reagents   Protease Activity Assays/Reagents  
     DNA Damage/Repair Kits/Reagents   Multiplex/Array Assay Kits/Reagents  
     Cell Selection/Detection Kits/Reagents   ELISA/Assay Development Kits/Reagents  
     Phosphatase Activity Assays/Reagents   Recombinant/Natural Proteins  
     Tagged/untagged cDNA clones
     Validated SYBR primer pairs
     Purified proteins from HEK293T cells
     Lysates
     Western blot validated antibodies
     shRNA in GFP-retroviral vector
     siRNA
     Custom Immunoassay Development
     Fluorogenic Cell Assay Kits
     miRNA Primers for qPCR Assays
     3' UTR Clones for miRNA Target Studies
     miRNA Expression Plasmids

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of CTR9
     SeqTarget long-range PCR primers for resequencing CTR9
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for CTR9
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of CTR9
     GenScript Custom Purified and Recombinant Proteins Services for CTR9 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for CTR9
     GenScript Custom Assay Services for CTR9 GenScript Custom Superior Antibodies Services for CTR9
     GenScript Custom overexpressing Cell Line Services for CTR9 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in CTR9 promoter
     Search Chromatin IP Primers for CTR9
     RT2 qPCR Primer Assay for CTR9
     GNC Network for CTR9
     Search for Assays for microRNAs that regulate CTR9
     SABiosciences Custom PCR Arrays for CTR9
     Search Tocris compounds for CTR9
     Browse Sino Biological Proteins and Antibodies
     cDNA Clones for CTR9
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     Antibodies for CTR9
     Lysates for CTR9
     Browse antibodies at Epitomics
     Browse ProSpec Recombinant Proteins

     Browse ELISAs and CLIAs at Uscn
           

    GeneCards Homepage - Last full update: 30 Dec 2010 - Incremental updates: 9 Jan 2011 , 10 Jan 2011

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