Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


Category   Symbol Source: HGNC EntrezGene Ensembl
GIFtS

Search by expression pattern Search by expression pattern



CTRL Gene

protein-coding   GIFtS: 56

GC16M053837
chymotrypsin-like
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
chymotrypsin-like1 2
CTRL12 3
MGC708212
chymotrypsin-like protease CTRL-12
EC 3.4.21.-3

External Ids:    HGNC: 25241   Entrez Gene: 15062   Ensembl: ENSG000001410867   UniProtKB: P403133   

Export aliases for CTRL gene to outside databases

Previous GC identifers: GC16M058658 GC16M068341 GC16M067698 GC16M067740 GC16M067741 GC16M066521 GC16M067963


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Gene Wiki entry for CTRL

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CTRL gene promoter:
         p53   SREBP-1a   SREBP-1b   SREBP-1c   IRF-7A   GATA-2   GATA-1   GATA-3   AhR   SRF   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for CTRL

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for CTRL 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q22.1   Ensembl cytogenetic band:  16q22.1   HGNC cytogenetic band: 16q22.1

CTRL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CTRL gene location

GeneLoc gene densities for chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M053837:  view genomic region     (about GC identifiers)

Start:
53,837,043 bp from pter
End:
53,839,335 bp from pter
Size:
2,293 bases
Orientation:
minus strand

1 alternative location:
Chr16- 67,963,473-67,965,770     
RefSeq DNA sequence:
NC_000016.9  NT_010498.15  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: CTRL_HUMAN, P40313 (See protein sequence)
Recommended Name: Chymotrypsin-like protease CTRL-1 precursor  
Size: 264 amino acids; 28002 Da

Explore the universe of human proteins at neXtProt for CTRL: NX_P40313 

REFSEQ proteins: NP_001898.1  

ENSEMBL proteins: 
ENSP00000406187 ENSP00000322629 


Human Recombinant Proteins 
Browse Purified and Recombinant Proteins at Millipore
Browse Human Recombinant Proteins at Sigma-Aldrich
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
OriGene Purified Protein: CTRL
OriGene Protein Over-expression Lysate: CTRL
GenScript Custom Purified and Recombinant Proteins Services for CTRL 
Novus Biologicals Protein for CTRL
Novus Biologicals Lysate for CTRL
Browse Sino Biological Recombinant Proteins
Browse ProSpec Recombinant Proteins

1 Gene Ontology (GO) cellular component term (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005615 extracellular space TAS9065485
About this table

CTRL for ontologies           About GeneDecksing



Antibodies for CTRL: 
Millipore Mono- and Polyclonal Antibodies for the study of CTRL
Sigma-Aldrich Antibodies for CTRL
Browse R&D Systems for Antibodies
Browse OriGene Antibodies
GenScript Custom Superior Antibodies Services for CTRL 
Novus Biologicals Antibody for CTRL
Browse antibodies at Epitomics

Assays for CTRL: 
Browse Kits and Assays available from Millipore
Browse ELISAs at Sigma-Aldrich
OriGene Custom Immunoassay Development 
Browse OriGene Fluorogenic Cell Assay Kits 
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for CTRL 
Browse Enzo Life Sciences for kits & assays
Uscn ELISAs and CLIAs for CTRL 


(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

CTRL for domains           About GeneDecksing

4 InterPro domains/families:
 IPR001314 Peptidase_S1A
 IPR009003 Ser/Cys_Pept_Trypsin-like
 IPR001254 Peptidase_S1_S6
 IPR018114 Peptidase_S1/S6_AS

Graphical View of Domain Structure for InterPro Entry P40313

ProtoNet protein and cluster: P40313

2 Blocks protein families:
IPB001254 Serine protease
IPB001314 Chymotrypsin serine protease family (S1) signature


UniProtKB/Swiss-Prot: CTRL_HUMAN, P40313
Similarity: Belongs to the peptidase S1 family
Similarity: Contains 1 peptidase S1 domain


(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

Inhib.
RNA:
    
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich siRNA Panels and siRNA for CTRL
Sigma-Aldrich shRNA for CTRL
OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): CTRL
OriGene shRNA RFP (see all 2): CTRL
OriGene basic RS shRNA (see all 2): CTRL
OriGene siRNA: CTRL
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of CTRL 
miRNA:Sigma-Aldrich microRNA Mimics for CTRL
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of CTRL 
Search SABiosciences for Assays for microRNAs that regulate CTRL

Gene
Editing:
Browse CompoZr Knockout ZFN at Sigma-Aldrich 

Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
Browse iPSC Reprogramming Factors at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: CTRL
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: CTRL
OriGene untagged cDNA clones in CMV expression vector: CTRL
Browse 3'-UTR reporter clones for miRNA target validation 
Browse MicroRNA Expression Plasmids 
GenScript cDNA clone with any tag delivered in your preferred vector: CTRL 
Browse Sino Biological Human cDNA Clones

Cell
Lines:
  
GenScript Custom overexpressing Cell Line Services for CTRL 

Genatlas biochemistry entry for CTRL:
chymotrypsin protease-like,pancreas

4 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0003824 catalytic activity ----
GO:0004252 serine-type endopeptidase activity IEA--
GO:0008233 peptidase activity IEA--
GO:0008236 serine-type peptidase activity ----
About this table

CTRL for ontologies           About GeneDecksing


(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section


CTRL for pathways           About GeneDecksing

1 Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Pathway for  CTRL
    Lysine Degradation

2 Kegg Pathways  (Kegg details for CTRL):
    hsa04972 Pancreatic secretion
hsa04974 Protein digestion and absorption

    SABiosciences Custom Pathway-Focused PCR Arrays for CTRL 

    Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Molecular Interaction Network for CTRL
    SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CTRL

1 Interacting protein for CTRL (P403132) via UniProtKB, MINT, and/or STRING
InteractantInteraction Details
GeneCardExternal ID(s)
ING1Q9UK532MINT-6616081
About this table

2 Gene Ontology (GO) biological process terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0006508 proteolysis IEA--
GO:0007586 digestion TAS9065485
About this table

CTRL for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

CTRL for compounds           About GeneDecksing

Browse Small Molecules at Sigma-Aldrich
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CTRL
10/58 Novoseek chemical compound relationships for CTRL gene (see all 58)
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
zlyck 82.5 4 1874738 (1), 1653805 (1)
chymostatin 81.9 6 11112426 (1), 8031148 (1), 8022661 (1), 8458433 (1) (see all 6)
clasto-lactacystinbeta-lactone 77.7 2 9601040 (1), 16719460 (1)
3,4-dichloroisocoumarin 74.3 4 1356435 (1), 8431436 (1)
tpck 73.4 8 9178191 (2), 11112426 (1), 19653099 (1), 15197350 (1) (see all 6)
lactacystin 73.3 9 10856705 (1), 16941495 (1), 17140599 (1), 12146975 (1)
bortezomib 71.6 14 18502982 (2), 19946334 (2), 19020781 (1), 17616698 (1) (see all 6)
serine 71.2 36 8363563 (1), 11708923 (1), 15654079 (1), 19281249 (1) (see all 34)
n-acetyl-leu-leu-methioninal 67.4 1 8431436 (1)
mg 132 67.3 2 18565852 (1), 17352013 (1)
About this table



(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib.
RNA:
     
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich siRNA Panels and siRNA for CTRL
Sigma-Aldrich shRNA for CTRL
OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): CTRL
OriGene shRNA RFP (see all 2): CTRL
OriGene basic RS shRNA (see all 2): CTRL
OriGene siRNA: CTRL
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of CTRL 
miRNA: Sigma-Aldrich microRNA Mimics for CTRL
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of CTRL 
Search SABiosciences for Assays for microRNAs that regulate CTRL
Clones: Browse FLAG tag genes at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: CTRL
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: CTRL
OriGene untagged cDNA clones in CMV expression vector: CTRL
Browse 3'-UTR reporter clones for miRNA target validation 
Browse OriGene MicroRNA Expression Plasmids 
GenScript cDNA clone with any tag delivered in your preferred vector: CTRL 
Primers: OriGene genome-wide validated SYBR primer pairs: CTRL
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for CTRL: PPH19182A

REFSEQ mRNAs for CTRL gene: 

NM_001907.2  

Additional cDNA sequence: 

AK223172.1 BC039716.1 BC063475.1 X71877.1 

5 DOTS entries:

DT.441944  DT.97796543  DT.120704986  DT.100796135  DT.86840959 

24/282 AceView cDNA sequences (see all 282):

CR607369 BQ575297 BG654787 CF528911 BF925687 BM919892 BG231537 CF127806 
CB107038 BU689482 BM981173 X71877 BP432229 BI833975 AW954332 AJ573626 
BM919400 BG058596 BG392300 BI821068 BI771225 BQ083171 BM919492 CR619398 

highest scoring ESTs for CTRL:

X71877 AK090445 BE140225 BE969862 BC039716 BC063475 BI521033 BI832541 BI832697 BI834199 

Unigene Cluster for CTRL:

Chymotrypsin-like
Hs.654546  [show with all ESTs]
Unigene Representative Sequence: BM918604


GeneLoc Exon Structure

5/12 Alternative Splicing Database (ASD) splice patterns (SP) for CTRL (see all 12)

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b ^ 12 ^ 13a · 13b · 13c · 13d ^ 14 ^
SP1:                                      -     -                       -     -                                                                                 
SP2:                                                                                                              -                                   -         
SP3:                                                                                                              -     -           -                           
SP4:                                      -     -                                                                                                               
SP5:                                      -     -                                                                                                               

ExUns: 15 ^ 16a · 16b
SP1:                  
SP2:                  
SP3:                  
SP4:                  
SP5:                  

About this scheme

ECgene alternative splicing isoforms for CTRL
2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000432773 ENST00000319955(uc002euw.2)

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

CTRL expression in normal and diseased human tissues

1  / 2  / 3

6 probe-sets matching CTRL gene

Affymetrix
probe-set
Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
40204_at2, 3 U95-A 1 1.00 1.00 0.98 0.91 X71877 0.80 0.70 0.75 1
386_g_at2, 3 U95-A 1 1.00 1.00 0.99 1.00 X71874 0.20 0.50 0.38 1
385_at2, 3 U95-A 1 1.00 1.00 0.97 1.17 X71874 0.20 0.50 0.38 1
40205_g_at2, 3 U95-A 1 0.94 1.00 0.96 0.95 X71877 0.80 0.70 0.75 1
214377_s_at2, 3 U133-A 1 1.00 1.00 -- -- BF508685 0.40 0.50 0.45 1
214377_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
About this table

CTRL for expression           About GeneDecksing

Data from Genenote  (Publications) and GNF BioGPS
    About these images
CTRL gene expression
CTRL gene electronic northern expression
CTRL gene sage expression
About these images

CGAP SAGE TAG: CCGAGGCCGG

SOURCE GeneReport for Unigene cluster: Hs.654546

Expression variation in blood from EXPOLDB for CTRL

Primers: OriGene genome-wide validated SYBR primer pairs: CTRL
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for CTRL: PPH19182A
    SABiosciences Custom PCR Arrays for CTRL 


(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for CTRL gene from 5/7 species (see all 7)
Organism Gene Locus Description Human
Similarity
NCBI accessions
dog
(Canis familiaris)
CTRL1   -- chymotrypsin-like 88.26(n)
89.02(a)
611100  XM_848737.1  XP_853830.1 
chimpanzee
(Pan troglodytes)
CTRL1   -- chymotrypsin-like 99.37(n)
98.48(a)
454179  XM_511044.2  XP_511044.2 
rat
(Rattus norvegicus)
Ctrl1   -- chymotrypsin-like 85.1(n)
87.5(a)
117184  NM_054009.1  NP_446461.1 
mouse
(Mus musculus)
Ctrl1 , 5 8 (53.06 cM)5
chymotrypsin-like1, 5 84.22(n)1
86.36(a)1
1096601  NM_023182.21  NP_075671.11 
 AA2445425  AB0162285  (see all 14)
chicken
(Gallus gallus)
CTRL1   -- chymotrypsin-like 68.58(n)
64.12(a)
427531  XM_425105.2  XP_425105.1 
About this table        Species with no ortholog for CTRL

ENSEMBL Gene Tree for CTRL (if available)

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
Paralogs for CTRL gene
CELA12  CTRB12  CELA3A2  CELA2B2  CTRC2  CELA2A2  CTRB22  CELA3B2  

CTRL for paralogs           About GeneDecksing



(SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

10/46 NCBI SNPs in CTRL are shown (see all 46)
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidChr 16 posSequenceRecsAA
Chg
TypeMoreRecsAllele
freq
PopTotal
sample
More
----------
rs10797241,2
C67965592(-) GTGGGC/TAAAAG 1 -- int15Minor allele frequency- T:0.00MN NS EA 602
rs10797251,2
C67965550(-) AACAGG/TCCTGC 1 -- int15Minor allele frequency- T:0.00MN NS EA 598
rs10797261,2
C67964934(-) GCCCAC/TCCCCA 1 -- int14Minor allele frequency- T:0.00NA EA 134
rs11347601,2
C,F,67964203(+) GCAGAT/CGTGCT 2 /H /R ref1 mis117Minor allele frequency- C:0.18EA NA NS WA 2732
rs25498091,2
C67966330(+) TGTACA/GCAAAC 1 -- ng514Minor allele frequency- G:0.00NS EA 414
rs25498101,2
H67966812(+) aaatgA/Tgctgg 1 -- ng514Minor allele frequency- T:0.00NS EA 416
rs26652661,2
--67967147(+) agccgC/Ggcgtg 1 -- ng510--------
rs26652671,2
C67967616(+) TCAGCG/AGCCTG 1 -- ng514Minor allele frequency- A:0.00NS EA 420
rs45989041,2
C,F,67964604(+) TTCCTC/TCGTGT 1 -- int1 trp38Minor allele frequency- T:0.09NS EA NA WA 512
rs98888391,2
C,F,67966024(+) CCCTCG/CGTACT 1 -- ng5114Minor allele frequency- C:0.05NS EA NA 1066
About this table

HapMap Linkage Disequilibrium images for CTRL (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for CTRL: --

QIAGEN SeqTarget long-range PCR primers for resequencing CTRL 

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CTRL for disorders           About GeneDecksing

OMIM: 118888

10/14 Novoseek disease relationships for CTRL gene (see all 14)

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
netherton syndrome 57.7 1 16628198 (1)
prostate cancer 40.4 10 17541980 (2), 16651429 (1), 17308104 (1), 18304598 (1) (see all 8)
tumors 28.9 13 10894830 (1), 12460905 (1), 7957109 (1), 19671918 (1) (see all 12)
cancer 28.2 7 20514399 (2), 16455650 (1), 17982703 (1), 17541980 (1) (see all 5)
leukemia 26.7 3 14960234 (1), 15066131 (1), 18773885 (1)
alzheimers disease 19.9 2 10386971 (1), 8336143 (1)
breast cancer 17.7 5 15746161 (1), 19337512 (1), 19911377 (1), 16806088 (1) (see all 5)
metastasis 3.55 1 10894830 (1)
necrosis 0 1 7957109 (1)
cataract 0 5 17162884 (3)
About this table


Export disorders and mutations for CTRL gene to outside databases

(Possibly Related Articles in Doctor's Guide)
About This Section
  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
About This Section

10/233 PubMed articles for CTRL gene, integrated from 7 sources (see all 233):
(articles sorted by number of sources associating them with CTRL)
  1. A tight cluster of five unrelated human genes on chromosome 16q22.1. (PubMed id 8268911)1, 2, 3, 7 Larsen F.... Prydz H. (1993)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  3. Placenta-derived chymotrypsin-like protease (CLP) disturbs endothelial junctional structure in preeclampsia. (PubMed id 19126871)1, 7 Gu Y....Wang Y. (2009)
  4. Chymotrypsin-like protease (chymase) mediates endothe lial activation by factors derived from preeclamptic placentas. (PubMed id 19494363)1, 7 Yang Gu ....Yuping Wang . (2009)
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
  6. Mast cell chymase degrades apoE and apoA-II in apoA-I-knockout mouse plasma and reduces its ability to promote cellular cholesterol efflux. (PubMed id 12231569)1 Lee M....Kovanen P.T. (2002)
  7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
  8. Construction and characterization of a full length-enriched and a 5'- end-enriched cDNA library. (PubMed id 9373149)1 Suzuki Y.... Sugano S. (1997)
  9. A novel human chymotrypsin-like digestive enzyme. (PubMed id 9065485)1 Reseland J.E....Prydz H. (1997)
  10. Molecular cloning, expression pattern, and chromosomal localization of the human Na-Cl thiazide-sensitive cotransporter (SLC12A3). (PubMed id 8812482)1 Mastroianni N.... Casari G. (1996)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Disorders
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 1506 HGNC: 2524 AceView: CTRLandPSMB10 Ensembl:ENSG00000141086 euGenes: HUgn1506
ECgene: CTRL Kegg: 1506 H-InvDB: CTRL

(According to HUGE)
About This Section
  --

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
  --

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from XenneX, Inc.)
About This Section
Patent Information for CTRL gene:
Search GeneIP for patents involving CTRL

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
About This Section

 Millipore Custom Antibody & Bulk Services
 Millipore Preclinical / Clinical Development Services
 Millipore Immunoassay Services
 Millipore Target Screening & Profiling Services

 Predesigned and custom siRNAs for CTRL Antibodies for CTRL
 Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
 Lentivirus-delivered shRNAs for CTRL microRNA Mimics for CTRL
 "Your Favorite Gene" Pathways and Molecular Interaction Networks Browse Nano Scale siRNA at Sigma-Aldrich
 Browse iPSC Reprogramming Factors at Sigma-Aldrich Browse small molecules at Sigma-Aldrich
 Browse FLAG tag genes at Sigma-Aldrich Browse ELISAs at Sigma-Aldrich
 Browse microRNA Target Validation Systems at Sigma-Aldrich Browse CompoZr Knockout ZFN at Sigma-Aldrich
feedback
  
 Antibodies   Cell Culture Products  
 ELISAs   Flow Cytometry Kits  
 Primer Pairs   Kinase Activity Assays/Reagents  
 ELISpot Kits/Development Modules   TFB/Immunoprecipitation Assays  
 Apoptosis Detection Kits/Reagents   Protease Activity Assays/Reagents  
 DNA Damage/Repair Kits/Reagents   Multiplex/Array Assay Kits/Reagents  
 Cell Selection/Detection Kits/Reagents   ELISA/Assay Development Kits/Reagents  
 Phosphatase Activity Assays/Reagents   Recombinant/Natural Proteins  
 Tagged/untagged cDNA clones
 Validated SYBR primer pairs
 Purified proteins from HEK293T cells
 Lysates
 Western blot validated antibodies
 shRNA in GFP-retroviral vector
 siRNA
 Custom Immunoassay Development
 Fluorogenic Cell Assay Kits
 miRNA Primers for qPCR Assays
 3' UTR Clones for miRNA Target Studies
 miRNA Expression Plasmids

 
 
 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of CTRL
 SeqTarget long-range PCR primers for resequencing CTRL
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for CTRL
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of CTRL
 GenScript Custom Purified and Recombinant Proteins Services for CTRL GenScript cDNA clones with any tag delivered in your preferred vector for CTRL
 GenScript Custom Assay Services for CTRL GenScript Custom Superior Antibodies Services for CTRL
 GenScript Custom overexpressing Cell Line Services for CTRL CloneReady with Over 120,000 Genes
 Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
 Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
 Custom Peptide Services
 Search for Antibodies & Assays

 Regulatory tfbs in CTRL promoter
 Search Chromatin IP Primers for CTRL
 RT2 qPCR Primer Assay for CTRL
 GNC Network for CTRL
 Search for Assays for microRNAs that regulate CTRL
 SABiosciences Custom PCR Arrays for CTRL
 Search Tocris compounds for CTRL
 Browse Sino Biological Proteins and Antibodies
 Browse Sino Biological cDNA Clones
 Antibodies/Proteins Production Services
 Rabbit Monoclonal Antibody Platform
 Bulk Purchasing
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
 Novus Tissue Slides
 Antibodies for CTRL
 Proteins for CTRL
 Lysates for CTRL
 Browse antibodies at Epitomics
 Browse ProSpec Recombinant Proteins

 ELISAs and CLIAs for CTRL
       

GeneCards Homepage - Last full update: 30 Dec 2010 - Incremental updates: 9 Jan 2011 , 10 Jan 2011

View Random Gene

Category
GIFtS Group
The GeneCards human gene database gene index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

CTRL gene at Home site.
hostname: www-ab3 db genecards_305 index build: 81e solr: 1.4