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DNAJA2 Gene

protein-coding   GIFtS: 56

GC16M032879
DnaJ (Hsp40) homolog, subfamily A, member 2
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
DnaJ (Hsp40) homolog, subfamily A, member 21 2     RDJ22
CPR31 2 3 5     dnaJ homolog subfamily A member 22
HIRIP41 2 3     HIRA interacting protein 42
DNAJ1 2     cell cycle progression 3 protein2
DNJ31 2     DJA22
Renal carcinoma antigen NY-REN-142 3     PRO30152
Cell cycle progression restoration gene 3 protein2 3     Dj33
HIRA-interacting protein 42 3     Dnj33
DJ32 5     

External Ids:    HGNC: 148841   Entrez Gene: 102942   Ensembl: ENSG000000693457   UniProtKB: O608843   

Export aliases for DNAJA2 gene to outside databases

Previous GC identifers: GC16M037401 GC16M046931 GC16M046730 GC16M046771 GC16M045547


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DNAJA2:
The protein encoded by this gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate
molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a
conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a
cysteine-rich domain containing 4 motifs resembling a zinc finger domain. The product of this gene works as a
cochaperone of Hsp70s in protein folding and mitochondrial protein import in vitro. (provided by RefSeq)

UniProtKB/Swiss-Prot: DNJA2_HUMAN, O60884
Function: Co-chaperone of Hsc70

Gene Wiki entry for DNAJA2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DNAJA2 gene promoter:
         COUP-TF1   HNF-4alpha2   PPAR-gamma2   PPAR-gamma1   NF-E2   NF-E2 p45   ATF   Meis-1   HOXA9B   Lmo2   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for DNAJA2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for DNAJA2 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q12.1   Ensembl cytogenetic band:  16q12.1   HGNC cytogenetic band: 16q12.1

DNAJA2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DNAJA2 gene location

GeneLoc gene densities for chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M032879:  view genomic region     (about GC identifiers)

Start:
32,879,590 bp from pter
End:
32,897,952 bp from pter
Size:
18,363 bases
Orientation:
minus strand

1 alternative location:
Chr16- 46,989,274-47,007,625     
RefSeq DNA sequence:
NC_000016.9  NT_010498.15  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: DNJA2_HUMAN, O60884 (See protein sequence)
Recommended Name: DnaJ homolog subfamily A member 2  
Size: 412 amino acids; 45746 Da
Subcellular location: Membrane; Lipid-anchor (Potential)
Secondary accessions: B2R7L7 O14711

Explore the universe of human proteins at neXtProt for DNAJA2: NX_O60884 

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_005871.1  

    ENSEMBL proteins: 
    ENSP00000314030 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: DNAJA2
    OriGene Protein Over-expression Lysate: DNAJA2
    GenScript Custom Purified and Recombinant Proteins Services for DNAJA2 
    Novus Biologicals Protein for DNAJA2
    Novus Biologicals Lysate for DNAJA2
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins

    1 Gene Ontology (GO) cellular component term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016020 membrane IEA--
    About this table

    DNAJA2 for ontologies           About GeneDecksing



    Antibodies for DNAJA2: 
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for DNAJA2
    Browse R&D Systems for Antibodies
    OriGene Antibodies (see all 6): DNAJA2
    GenScript Custom Superior Antibodies Services for DNAJA2 
    Novus Biologicals Antibodies for DNAJA2
    Epitomics antibodies for DNAJA2

    Assays for DNAJA2: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for DNAJA2 
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for DNAJA2 


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    DNAJA2 for domains           About GeneDecksing

    5/8 InterPro domains/families (see all 8):
     IPR015609 Hsp40/DnaJ_Rel
     IPR008971 HSP40/DnaJ_pept-bd
     IPR002939 DnaJ_C
     IPR001623 DnaJ_N
     IPR018253 Heat_shock_DnaJ_CS

    Graphical View of Domain Structure for InterPro Entry O60884

    ProtoNet protein and cluster: O60884

    2 Blocks protein families:
    IPB001305 DnaJ central domain (CXXCXGXG)
    IPB003095 DnaJ protein family signature


    UniProtKB/Swiss-Prot: DNJA2_HUMAN, O60884
    Similarity: Contains 1 CR-type zinc finger
    Similarity: Contains 1 J domain


    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    UniProtKB/Swiss-Prot: DNJA2_HUMAN, O60884
    Function: Co-chaperone of Hsc70

    Inhib.
    RNA:
        
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich siRNA Panels and esiRNA and siRNA for DNAJA2
    Sigma-Aldrich shRNA for DNAJA2
    OriGene 29mer shRNA kits in GFP-retroviral vector: DNAJA2
    OriGene shRNA RFP: DNAJA2
    OriGene basic RS shRNA: DNAJA2
    OriGene siRNA: DNAJA2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of DNAJA2 
    miRNA:Sigma-Aldrich microRNA Mimics for DNAJA2
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of DNAJA2 
    8/17 SABiosciences Assays for microRNAs that regulate DNAJA2 (see all 17):
    hsa-miR-520f hsa-miR-520e hsa-miR-503 hsa-miR-372 hsa-miR-1323 hsa-miR-542-3p hsa-miR-520d-3p hsa-miR-376c

    Gene
    Editing:
    Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: DNAJA2
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: DNAJA2
    OriGene untagged cDNA clones in CMV expression vector (see all 2): DNAJA2
    OriGene 3'-UTR clone: DNAJA2 
    Browse MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for DNAJA2 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:
      
    GenScript Custom overexpressing Cell Line Services for DNAJA2 

    4 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005524 ATP binding IEA--
    GO:0031072 heat shock protein binding IEA--
    GO:0046872 metal ion binding IEA--
    GO:0051082 unfolded protein binding IEA--
    About this table

    DNAJA2 for ontologies           About GeneDecksing


    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section


    DNAJA2 for pathways           About GeneDecksing

    1 Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Pathway for  DNAJA2
        NRF2-mediated Oxidative Stress Response

    1 Kegg Pathway  (Kegg details for DNAJA2):
        hsa04141 Protein processing in endoplasmic reticulum

        SABiosciences Pathway-Focused PCR Arrays including DNAJA2: PAHS-076A PAHS-3401A 

        Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Molecular Interaction Network for DNAJA2
        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DNAJA2

    5/31 Interacting proteins for DNAJA2 (O608842) via UniProtKB, MINT, and/or STRING (see all 31)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATP1A1P050232MINT-6488488
    DDOSTP396562MINT-6488488
    DICER1Q9UPY32MINT-6488488
    EEF1A1P681042MINT-6488488
    EEF1A1P9P681042
    About this table

    3 Gene Ontology (GO) biological process terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006457 protein folding IEA--
    GO:0008284 positive regulation of cell proliferation TAS9383053
    GO:0009408 response to heat IEA--
    About this table

    DNAJA2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    DNAJA2 for compounds           About GeneDecksing

    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DNAJA2
    3 Novoseek chemical compound relationships for DNAJA2 gene
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    atp 29.3 8 10493815 (4)
    adp 28.4 5 10493815 (2), 8922377 (1)
    zinc 3.28 6 12941935 (4)
    About this table



    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section

    Inhib.
    RNA:
         
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich siRNA Panels and esiRNA and siRNA for DNAJA2
    Sigma-Aldrich shRNA for DNAJA2
    OriGene 29mer shRNA kits in GFP-retroviral vector: DNAJA2
    OriGene shRNA RFP: DNAJA2
    OriGene basic RS shRNA: DNAJA2
    OriGene siRNA: DNAJA2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of DNAJA2 
    miRNA: Sigma-Aldrich microRNA Mimics for DNAJA2
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of DNAJA2 
    8/17 SABiosciences Assays for microRNAs that regulate DNAJA2 (see all 17):
    hsa-miR-520f hsa-miR-520e hsa-miR-503 hsa-miR-372 hsa-miR-1323 hsa-miR-542-3p hsa-miR-520d-3p hsa-miR-376c
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: DNAJA2
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: DNAJA2
    OriGene untagged cDNA clones in CMV expression vector (see all 2): DNAJA2
    OriGene 3'-UTR Clone: DNAJA2 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for DNAJA2 
    Primers: OriGene genome-wide validated SYBR primer pairs: DNAJA2
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for DNAJA2: PPH05916A

    REFSEQ mRNAs for DNAJA2 gene: 

    NM_005880.3  

    Additional cDNA sequence: 

    AF011793.1 AF088046.1 AJ001309.1 AK313031.1 BC013044.2 BC015809.2 CR600360.1 CR616567.1 
    CR621166.1 CR622758.1 Y13350.1 

    9 DOTS entries:

    DT.407476  DT.100809136  DT.100809135  DT.100809126  DT.100809132  DT.100809133  DT.87016563  DT.100809131 
    DT.120676773 

    24/300 AceView cDNA sequences (see all 300):

    BM930354 BE000270 AI273537 BQ774167 CR622758 BU674653 AU139290 BC015809 
    AF088046 BC013044 CD678299 BX955324 AW057513 BQ645095 AW385136 BU173271 
    BU192281 BP346017 BE385295 BG250409 AA677397 CN484407 CR621166 BQ774716 

    highest scoring ESTs for DNAJA2:

    AA307662 AJ001309 AL558670 AL603007 AL702679 AL702805 AL711727 AU099048 AU133833 AV657203 

    Unigene Cluster for DNAJA2:

    DnaJ (Hsp40) homolog, subfamily A, member 2
    Hs.368078  [show with all ESTs]
    Unigene Representative Sequence: NM_005880


    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for DNAJA2 (see all 6)

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c · 3d ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10
    SP1:                          -                                                                                             
    SP2:                                                                                            -                 -         
    SP3:                          -                 -     -     -                                                               
    SP4:                                                                                                                        
    SP5:                                                                                                                        

    About this scheme

    ECgene alternative splicing isoforms for DNAJA2
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000317089(uc002eeo.2 uc002eep.2)

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    DNAJA2 expression in normal and diseased human tissues

    1  / 2  / 3

    6 probe-sets matching DNAJA2 gene

    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    34201_at2, 3 U95-A 1 0.50 1.00 0.97 0.87 Y13350 0.60 1.00 0.82 1
    51644_at2, 3 U95-B 1 0.31 1.00 0.98 1.13 AI560867 0.40 1.00 0.76 1
    209157_at2, 3 U133-A 1 1.00 1.00 -- -- AF011793 0.60 1.00 0.82 1
    226994_at2, 3 U133-B 1 0.55 1.00 -- -- AW057513 0.40 1.00 0.76 1
    209157_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    226994_at2 U133Plus2 1 0.55 1.00 -- -- -- -- -- -- --
    About this table

    DNAJA2 for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    DNAJA2 gene expression
    DNAJA2 gene electronic northern expression
    DNAJA2 gene sage expression
    About these images

    CGAP SAGE TAG: GAAAAAAATG

    SOURCE GeneReport for Unigene cluster: Hs.368078

    Expression variation in blood from EXPOLDB for DNAJA2

    Primers: OriGene genome-wide validated SYBR primer pairs: DNAJA2
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for DNAJA2: PPH05916A
        SABiosciences Expression via Pathway-Focused PCR Arrays including DNAJA2: PAHS-076A PAHS-3401A 


    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section

    Orthologs for DNAJA2 gene from 5/23 species (see all 23)
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    DNAJA21   -- DnaJ (Hsp40) homolog, subfamily A, member 2 94.99(n)
    100(a)
    478143  XM_535319.2  XP_535319.2 
    chimpanzee
    (Pan troglodytes)
    DNAJA21   -- DnaJ (Hsp40) homolog, subfamily A, member 2 99.84(n)
    100(a)
    473274  XM_528644.2  XP_528644.2 
    cow
    (Bos taurus)
    DNAJA21   -- DnaJ (Hsp40) homolog, subfamily A, member 2 93.93(n)
    99.51(a)
    360006  NM_001040491.1  NP_001035581.1 
    rat
    (Rattus norvegicus)
    Dnaja21   -- DnaJ (Hsp40) homolog, subfamily A, member 2 92.39(n)
    99.51(a)
    84026  NM_032079.2  NP_114468.2 
    mouse
    (Mus musculus)
    Dnaja21 , 5 8 (41.61 cM)5
    DnaJ (Hsp40) homolog, subfamily A, member 21, 5 92.56(n)1
    99.51(a)1
    564451  NM_019794.21  NP_062768.11 
     AA1074715  AA7639455  (see all 19)
    About this table        Species with no ortholog for DNAJA2

    ENSEMBL Gene Tree for DNAJA2 (if available)

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
    Paralogs for DNAJA2 gene
    DNAJA12  DNAJA42  DNAJB112  

    DNAJA2 for paralogs           About GeneDecksing



    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/155 NCBI SNPs in DNAJA2 are shown (see all 155)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 16 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ----------
    rs128361,2
    F46990781(+) TTAAAT/ATATAC 1 -- ut311Minor allele frequency- A:0.24MN 186
    rs10456501,2
    --47002026(-) ACTTAG/TCAAGA 2 S I ref1 mis11Minor allele frequency- T:0.00MN 184
    rs10653321,2
    H47005346(-) TTTTTG/TGTGGG 2 G C ref1 mis15Minor allele frequency- T:0.00MN NS EA 590
    rs13624061,2
    C,F,A,H,46996557(-) TAGCTC/ACTTCC 1 -- int120Minor allele frequency- A:0.14NS NA EA WA 744
    rs14202331,2
    C46993892(-) ACCTAG/TTCCAT 1 -- int10--------
    rs20345981,2
    C,F,O,A,H,47001626(-) AATTTC/TTGTGT 1 -- int126Minor allele frequency- T:0.13NS EA NA 3478
    rs22337751,2
    C47001154(+) ctgagA/Cccctc 1 -- int10--------
    rs22337761,2
    C47001272(+) agtgcC/Tggaat 1 -- int10--------
    rs22337771,2
    C,47005053(+) TCATTA/GAAAAA 1 -- int11Minor allele frequency- G:0.01EA 88
    rs22903151,2
    H47006421(-) CTTCTC/GTACCA 1 -- int15Minor allele frequency- G:0.01EA NS 1902
    About this table

    HapMap Linkage Disequilibrium images for DNAJA2 (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for DNAJA2: --

    QIAGEN SeqTarget long-range PCR primers for resequencing DNAJA2 

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    DNAJA2 for disorders           About GeneDecksing

    OMIM: 611322

    2 Novoseek disease relationships for DNAJA2 gene

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    shock 39.7 5 1370300 (2), 8334160 (2), 9159391 (1)
    tumors 0 1 11707338 (1)
    About this table


    Export disorders and mutations for DNAJA2 gene to outside databases

    (Possibly Related Articles in Doctor's Guide)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/52 PubMed articles for DNAJA2 gene, integrated from 7 sources (see all 52):
    (articles sorted by number of sources associating them with DNAJA2)
    1. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. A tagging-via-substrate technology for detection and proteomics of farnesylated proteins. (PubMed id 15308774)1, 2 Kho Y.... Zhao Y. (2004)
    4. Human DnaJ homologs dj2 and dj3, and bag-1 are positive cochaperones of hsc70. (PubMed id 10816573)1, 2 Terada K. and Mori M. (2000)
    5. Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature. (PubMed id 11147971)1, 3 Ohtsuka K. and Hata M. (2000)
    6. Antigens recognized by autologous antibody in patients with renal- cell carcinoma. (PubMed id 10508479)1, 2 Scanlan M.J....Old L.J. (1999)
    7. Core histones and HIRIP3, a novel histone-binding protein, directly interact with WD repeat protein HIRA. (PubMed id 9710638)1, 3 Lorain S.... Lipinski M. (1998)
    8. Human CPR (cell cycle progression restoration) genes impart a Far- phenotype on yeast cells. (PubMed id 9383053)1, 2 Edwards M.C.... Elledge S.J. (1997)
    9. Hsp40 chaperones promote degradation of the HERG pota ssium channel. (PubMed id 19940115)1 Walker V.E....Shrier A. (2010)
    10. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10294 HGNC: 14884 AceView: DNAJA2 Ensembl:ENSG00000069345 euGenes: HUgn10294
    ECgene: DNAJA2 Kegg: 10294 H-InvDB: DNAJA2

    (According to HUGE)
    About This Section
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    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
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    Patent Information for DNAJA2 gene:
    Search GeneIP for patents involving DNAJA2

    GeneCards and IP:
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