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DNAJC12 Gene

protein-coding   GIFtS: 47

GC10M063555
DnaJ (Hsp40) homolog, subfamily C, member 12
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

Aliases &
Descriptions
for DNAJC12 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases & Descriptions
DnaJ (Hsp40) homolog, subfamily C, member 121 2
JDP11 2 3 5
J domain-containing protein 12 3
dnaJ homolog subfamily C member 122
J domain containing protein 1 (JDP1)2
J domain protein 12

External Ids:    HGNC: 289081   Entrez Gene: 565212   Ensembl: ENSG000001081767   UniProtKB: Q9UKB33   

Export aliases for DNAJC12 gene to outside databases

Previous GC identifers: GC10M068902 GC10M069226 GC10M069556


Summaries
for DNAJC12 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for DNAJC12:
This gene encodes a member of a subclass of the HSP40/DnaJ protein family. Members of this family of proteins are
associated with complex assembly, protein folding, and export. Two transcript variants encoding distinct isoforms have
been identified for this gene. (provided by RefSeq)


Genomic Views
for DNAJC12 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DNAJC12 gene promoter:
         NRSF form 1   NRSF form 2   POU2F1   NF-YA   CP1C   CP1A   NF-Y   LCR-F1   HNF-4alpha2   COUP-TF1   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for DNAJC12

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q22.1   Ensembl cytogenetic band:  10q21.3   HGNC cytogenetic band: 10q21.3

DNAJC12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DNAJC12 gene location

GeneLoc gene densities for chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M063555:  view genomic region     (about GC identifiers)

Start:
 63,555,841 bp from pter
End:
 63,597,255 bp from pter
Size:
 41,415 bases
Orientation:
 minus strand

1 alternative location:
Chr10- 69,556,427-69,597,924     
RefSeq DNA sequence:
NC_000010.10  NT_030059.13  

Proteins
for DNAJC12 gene

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section
UniProtKB/Swiss-Prot: DJC12_HUMAN, Q9UKB3 (See protein sequence)
Recommended Name: DnaJ homolog subfamily C member 12  
Size: 198 amino acids; 23415 Da
PDB structures from and Proteopedia :
2CTQ (3D)    
Secondary accessions: Q5JVQ1 Q9UKB2
Alternative splicing: 2 isoforms:  Q9UKB3-1   Q9UKB3-2   

Explore the universe of human proteins at neXtProt for DNAJC12: NX_Q9UKB3 

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins (2 alternative transcripts): 
    NP_068572.1  NP_957714.1  


    ENSEMBL proteins: 
    ENSP00000225171 ENSP00000343575 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    GenScript Custom Purified and Recombinant Proteins Services for DNAJC12 
    Novus Biologicals Protein for DNAJC12
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins


    Antibodies for DNAJC12: 
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for DNAJC12
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    GenScript Custom Superior Antibodies Services for DNAJC12 
    Novus Biologicals Antibody for DNAJC12
    Browse antibodies at Epitomics

    Assays for DNAJC12: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for DNAJC12 
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for DNAJC12 

    Protein Domains/
    Families
    for DNAJC12 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    DNAJC12 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR015609 Hsp40/DnaJ_Rel
     IPR001623 DnaJ_N

    Graphical View of Domain Structure for InterPro Entry Q9UKB3

    ProtoNet protein and cluster: Q9UKB3

    UniProtKB/Swiss-Prot: DJC12_HUMAN, Q9UKB3
    Similarity: Contains 1 J domain


    Gene Function
    for DNAJC12 gene

    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:            		Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for DNAJC12
    Sigma-Aldrich shRNA for DNAJC12
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): DNAJC12
    OriGene shRNA RFP (see all 2): DNAJC12
    OriGene basic RS shRNA (see all 2): DNAJC12
    OriGene siRNA (see all 2): DNAJC12
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of DNAJC12 
    miRNA:Sigma-Aldrich microRNA Mimics for DNAJC12
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of DNAJC12 
    2 SABiosciences Assays for microRNAs that regulate DNAJC12:
    hsa-miR-23b hsa-miR-23a

    Gene
    Editing:    		Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): DNAJC12
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): DNAJC12
    OriGene untagged cDNA clones in CMV expression vector (see all 3): DNAJC12
    OriGene 3'-UTR clone (see all 2): DNAJC12 
    Browse MicroRNA Expression Plasmids 
    GenScript cDNA clones with any tag delivered in your preferred vector (see all 2): DNAJC12 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:          		GenScript Custom overexpressing Cell Line Services for DNAJC12 

    2 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0031072 heat shock protein binding IEA--
    GO:0051082 unfolded protein binding IEA--
    About this table

    DNAJC12 for ontologies           About GeneDecksing


    Pathways & Interactions
    for DNAJC12 gene

    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section

        SABiosciences Pathway-Focused PCR Array including DNAJC12: PAHS-076A 

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DNAJC12

    1 Gene Ontology (GO) biological process term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006457 protein folding IEA--
    About this table

    DNAJC12 for ontologies           About GeneDecksing



    Drugs & Compounds
    for DNAJC12 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section
    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DNAJC12


    Transcripts
    for DNAJC12 gene

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section
    Inhib.
    RNA:             		Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for DNAJC12
    Sigma-Aldrich shRNA for DNAJC12
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): DNAJC12
    OriGene shRNA RFP (see all 2): DNAJC12
    OriGene basic RS shRNA (see all 2): DNAJC12
    OriGene siRNA (see all 2): DNAJC12
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of DNAJC12 
    miRNA: Sigma-Aldrich microRNA Mimics for DNAJC12
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of DNAJC12 
    2 SABiosciences Assays for microRNAs that regulate DNAJC12:
    hsa-miR-23b hsa-miR-23a
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): DNAJC12
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): DNAJC12
    OriGene untagged cDNA clones in CMV expression vector (see all 3): DNAJC12
    OriGene 3'-UTR Clone (see all 2): DNAJC12 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript cDNA clones with any tag delivered in your preferred vector (see all 2): DNAJC12 
    Primers: OriGene genome-wide validated SYBR primer pairs: DNAJC12
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for DNAJC12: PPH15303A

    REFSEQ mRNAs for DNAJC12 gene (2 alternative transcripts): 

    NM_021800.2  NM_201262.1  

    Additional cDNA sequence: 

    AF176012.1 AF176013.1 AK289537.1 BC017018.1 CR457184.1 CR594852.1 

    5 DOTS entries:

    DT.91765210  DT.95129154  DT.416346  DT.91976343  DT.121246995 

    24/142 AceView cDNA sequences (see all 142):

    F03969 NM_021800 AA947853 Z45047 CR594852 AW511355 BE219867 F07732 
    T35837 AI392695 AF176013 BI861213 BI253314 BX091336 BF794642 AA704976 
    AA699661 BC017018 BI438228 AA890216 AA719166 CB117729 AW614546 BG497386 

    highest scoring ESTs for DNAJC12:

    AI825855 AI761752 AA523419 AA699661 AF176012 AF176013 AW451858 BE048700 BE219867 BE789578 

    Unigene Cluster for DNAJC12:

    DnaJ (Hsp40) homolog, subfamily C, member 12
    Hs.260720  [show with all ESTs]
    Unigene Representative Sequence: NM_021800


    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for DNAJC12 (see all 6)

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d ^ 8a · 8b ^ 9a · 9b
    SP1:                          -     -     -                             -     -                           
    SP2:                          -     -     -           -                 -     -                           
    SP3:                          -     -     -                             -     -                           
    SP4:                          -     -                 -                                                   
    SP5:                                      -           -                                                   

    About this scheme

    ECgene alternative splicing isoforms for DNAJC12
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000480180 ENST00000225171(uc001jnb.2) ENST00000480963 ENST00000483798
    ENST00000339758(uc001jnc.2)

    Expression
    for DNAJC12 gene

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    DNAJC12 expression in normal and diseased human tissues

    1  / 2  / 3

    9 probe-sets matching DNAJC12 gene

    Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    54731_at2, 3 U95-B 1 1.00 1.00 0.98 1.34 AI761752 0.80 1.00 0.91 1
    54727_g_at2, 3 U95-B 1 1.00 1.00 0.98 1.00 AI825855 1.00 0.90 0.95 1
    54723_at2, 3 U95-B 1 0.69 1.00 0.86 0.69 AI825855 1.00 0.90 0.95 1
    223721_s_at2, 3 U133-B 1 1.00 1.00 -- -- AF176013 0.80 0.88 0.84 1
    218976_at2, 3 U133-A 1 1.00 1.00 -- -- NM_021800 0.60 1.00 0.82 1
    223722_at2, 3 U133-B 1 0.73 1.00 -- -- AF176013 0.80 0.88 0.84 1
    223721_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    218976_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    223722_at2 U133Plus2 1 0.73 1.00 -- -- -- -- -- -- --
    About this table

    DNAJC12 for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    DNAJC12 gene expression
    DNAJC12 gene electronic northern expression
    DNAJC12 gene sage expression
    About these images

    CGAP SAGE TAG: --

    SOURCE GeneReport for Unigene cluster: Hs.260720

    UniProtKB/Swiss-Prot: DJC12_HUMAN, Q9UKB3
    Tissue specificity: Expressed at high levels in brain, heart, and testis, and at reduced levels in kidney and stomach

    Primers: OriGene genome-wide validated SYBR primer pairs: DNAJC12
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for DNAJC12: PPH15303A
        SABiosciences Expression via Pathway-Focused PCR Array including DNAJC12: PAHS-076A 


    Orthologs
    for DNAJC12 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for DNAJC12 gene from 5/10 species (see all 10)
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 DNAJC121   -- DnaJ (Hsp40) homolog, subfamily C, member 12 91.07(n)
    86.27(a)    		 479224  XM_536366.2  XP_536366.2 
    chimpanzee
    (Pan troglodytes)    		 DNAJC121   -- DnaJ (Hsp40) homolog, subfamily C, member 12 99.16(n)
    97.47(a)    		 466287  XM_521687.2  XP_521687.2 
    cow
    (Bos taurus)    		 DNAJC121   -- DnaJ (Hsp40) homolog, subfamily C, member 12 89.23(n)
    85.35(a)    		 281259  NM_174096.2  NP_776521.1 
    rat
    (Rattus norvegicus)    		 Dnajc121   -- DnaJ (Hsp40) homolog, subfamily C, member 12 80.13(n)
    76.26(a)    		 619393  NM_001034032.1  NP_001029204.1 
    mouse
    (Mus musculus)    		 Dnajc121 , 5 10 (32.57 cM)5
    		 DnaJ (Hsp40) homolog, subfamily C, member 121, 5 80.13(n)1
    77.27(a)1    		 300451  NM_013888.21  NP_038916.11 
     AF1329065  AI8524455  (see all 12)
    About this table        Species with no ortholog for DNAJC12

    ENSEMBL Gene Tree for DNAJC12 (if available)

    Paralogs
    for DNAJC12 gene

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
    Paralogs for DNAJC12 gene
    DNAJC172  

    DNAJC12 for paralogs           About GeneDecksing



    Genomic Variants
    for DNAJC12 gene

    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/437 NCBI SNPs in DNAJC12 are shown (see all 437)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 10 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ----------
    rs9626081,2
    		C,F,A,H,69583206(-) ataggT/Cgtgag 1 -- int17Minor allele frequency- C:0.12NA WA 16
    rs18854741,2
    		C,F,A,69566751(+) CGCAGT/GGGCTC 1 -- int11Minor allele frequency- G:0.26EA 88
    rs19857971,2
    		C,A,69595972(-) cctccT/Ccttct 1 -- int1 trp33Minor allele frequency- C:0.17NA WA 6
    rs20251611,2
    		C,A,H69594384(+) agttcG/Aaggcc 1 -- int13Minor allele frequency- A:0.00NA WA 6
    rs21460551,2
    		C,F,69560761(+) TTATTC/TTAGAA 1 -- int110Minor allele frequency- T:0.02NS EA NA WA 430
    rs22737711,2
    		C,F,A,69597786(+) AATCAG/ATCCTT 1 -- ut5118Minor allele frequency- A:0.26EA NS NA 2990
    rs22737721,2
    		C,F,69597824(+) AGCTTC/TGAATT 1 -- ut5119Minor allele frequency- T:0.29EA NA NS 3072
    rs23944391,2
    		H69572814(+) aattcT/Gtaact 1 -- int14Minor allele frequency- G:0.00NS EA 414
    rs30846131,2
    		C69593213(+) tctct-/CTCTCT
                gtctc     		1 -- int1 trp31Minor allele frequency- CTCTCT:0.00NA 2
    rs42373141,2
    		C,F,A,69557343(+) AAGTAC/ATATAA 1 -- int11Minor allele frequency- A:0.35EA 88
    About this table

    HapMap Linkage Disequilibrium images for DNAJC12 (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for DNAJC12: --

    QIAGEN SeqTarget long-range PCR primers for resequencing DNAJC12 

    Disorders & Mutations
    for DNAJC12 gene

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    DNAJC12 for disorders           About GeneDecksing

    OMIM: 606060

    Human Genome Epidemiology (HuGE) Navigator: DNAJC12 (2 documents)

    Export disorders and mutations for DNAJC12 gene to outside databases

    Medical News
    for DNAJC12 gene

    (Possibly Related Articles in Doctor's Guide)
    About This Section
    		   --

    Publications
    for DNAJC12 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    8 PubMed articles for DNAJC12 gene integrated from 7 sources:
    (articles sorted by number of sources associating them with DNAJC12)
    1. Characterization of JDP genes, an evolutionarily conserved J domain- only protein family, from human and moths. (PubMed id 10760603)1, 2, 3 Lee J.... Chung J.H. (2000)
    2. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. JDP1 (DNAJC12/Hsp40) expression in breast cancer and its association with estrogen receptor status. (PubMed id 16391838)1, 7 De Bessa S.A....Nagai M.A. (2006)
    5. Association studies of 23 positional/functional candidate genes on chromosome 10 in late-onset Alzheimer's disease. (PubMed id 17373700)1 Morgan A.R....Williams J. (2007)
    6. Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PubMed id 16712791)1 Wang A.G....Kim N.S. (2006)
    7. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1 Grupe A....Goate A. (2006)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    External Searches for DNAJC12 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing DNAJC12 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 56521 HGNC: 28908 AceView: DNAJC12 Ensembl:ENSG00000108176 euGenes: HUgn56521
    ECgene: DNAJC12 H-InvDB: DNAJC12

    Other Databases showing DNAJC12 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing DNAJC12 gene

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    		   --

    Intellectual Property
    for DNAJC12 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
    About This Section
    		Patent Information for DNAJC12 gene:
    Search GeneIP for patents involving DNAJC12

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for DNAJC12 gene

    (Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
    Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
    About This Section

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services

     Predesigned and custom siRNAs for DNAJC12 Antibodies for DNAJC12
     Super-pooled esiRNAs for DNAJC12 Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for DNAJC12 microRNA Mimics for DNAJC12
     "Your Favorite Gene" Pathways and Molecular Interaction Networks Browse Nano Scale siRNA at Sigma-Aldrich
     Browse iPSC Reprogramming Factors at Sigma-Aldrich Browse small molecules at Sigma-Aldrich
     Browse FLAG tag genes at Sigma-Aldrich Browse ELISAs at Sigma-Aldrich
     Browse microRNA Target Validation Systems at Sigma-Aldrich Browse CompoZr Knockout ZFN at Sigma-Aldrich
    feedback
      
     Antibodies   Cell Culture Products  
     ELISAs   Flow Cytometry Kits  
     Primer Pairs   Kinase Activity Assays/Reagents  
     ELISpot Kits/Development Modules   TFB/Immunoprecipitation Assays  
     Apoptosis Detection Kits/Reagents   Protease Activity Assays/Reagents  
     DNA Damage/Repair Kits/Reagents   Multiplex/Array Assay Kits/Reagents  
     Cell Selection/Detection Kits/Reagents   ELISA/Assay Development Kits/Reagents  
     Phosphatase Activity Assays/Reagents   Recombinant/Natural Proteins  
     Tagged/untagged cDNA clones
     Validated SYBR primer pairs
     Purified proteins from HEK293T cells
     Lysates
     Western blot validated antibodies
     shRNA in GFP-retroviral vector
     siRNA
     Custom Immunoassay Development
     Fluorogenic Cell Assay Kits
     miRNA Primers for qPCR Assays
     3' UTR Clones for miRNA Target Studies
     miRNA Expression Plasmids

         		 
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of DNAJC12
     SeqTarget long-range PCR primers for resequencing DNAJC12
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of DNAJC12
     GenScript Custom Purified and Recombinant Proteins Services for DNAJC12 GenScript cDNA clones with any tag delivered in your preferred vector for DNAJC12
     GenScript Custom Assay Services for DNAJC12 GenScript Custom Superior Antibodies Services for DNAJC12
     GenScript Custom overexpressing Cell Line Services for DNAJC12 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in DNAJC12 promoter
     Search Chromatin IP Primers for DNAJC12
     RT2 qPCR Primer Assay for DNAJC12
     Search GNC Networks for DNAJC12
     Assays for microRNAs that regulate DNAJC12
     SABiosciences PCR Arrays including DNAJC12
     Search Tocris compounds for DNAJC12
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     Antibodies for DNAJC12
     Proteins for DNAJC12
     Browse antibodies at Epitomics
     Browse ProSpec Recombinant Proteins

     ELISAs and CLIAs for DNAJC12
           

    GeneCards Homepage - Last full update: 30 Dec 2010 - Incremental updates: 10 Jan 2011 , 10 Jan 2011

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