Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


Category   Symbol Source: HGNC EntrezGene Ensembl
GIFtS

Search by expression pattern Search by expression pattern



DYNLRB2 Gene

protein-coding   GIFtS: 49

GC16P066331
dynein, light chain, roadblock-type 2
(Previous names: dynein, cytoplasmic, light polypeptide 2B )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: DNCL2B)
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
dynein, light chain, roadblock-type 21 2     Roadblock domain-containing protein 22 3
DNLC2B1 2 3     bithoraxoid-like protein2
ROBLD21 2 3     roadblock/LC7-like2
DNCL2B2 3 5     roadblock domain containing 22
dynein, cytoplasmic, light polypeptide 2B1 2     MGC620332
Dynein light chain 2B, cytoplasmic2 3     dynein light chain roadblock-type 22

External Ids:    HGNC: 154671   Entrez Gene: 836572   Ensembl: ENSG000001685897   UniProtKB: Q8TF093   

Export aliases for DYNLRB2 gene to outside databases

Previous GC identifers: GC16P079133 GC16P080574


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: DLRB2_HUMAN, Q8TF09
Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are
thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic
dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DYNLRB2 gene promoter:
         Cart-1   FOXO1a   POU2F1   Cdc5   GATA-3   GATA-2   GATA-1   FOXO3a   FOXO3b   FOXO4   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for DYNLRB2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q23.3   Ensembl cytogenetic band:  16q23.2   HGNC cytogenetic band: 16q23.3

DYNLRB2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DYNLRB2 gene location

GeneLoc gene densities for chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P066331:  view genomic region     (about GC identifiers)

Start:
66,331,392 bp from pter
End:
66,341,090 bp from pter
Size:
9,699 bases
Orientation:
plus strand

1 alternative location:
Chr16+ 80,574,854-80,584,541     
RefSeq DNA sequence:
NC_000016.9  NT_010498.15  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: DLRB2_HUMAN, Q8TF09 (See protein sequence)
Recommended Name: Dynein light chain roadblock-type 2  
Size: 96 amino acids; 10855 Da
Subunit: Homodimer (Probable). The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a
number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light
chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer
serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs
bind directly to the HC dimer and the LCs assemble on the IC dimer. Interacts with DYNC1I1 and DYNC1I2.
Self-associates. Interacts with DYNLRB1
Subcellular location: Cytoplasm
Miscellaneous: Expression is significantly down-regulated in hepatocellular carcinoma (HCC) patients

Explore the universe of human proteins at neXtProt for DYNLRB2: NX_Q8TF09 

REFSEQ proteins: NP_570967.1  

ENSEMBL proteins: 
ENSP00000342009 ENSP00000302936 


Human Recombinant Proteins 
Browse Purified and Recombinant Proteins at Millipore
Browse Human Recombinant Proteins at Sigma-Aldrich
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
Browse OriGene Protein Over-expression Lysates
GenScript Custom Purified and Recombinant Proteins Services for DYNLRB2 
Browse Sino Biological Recombinant Proteins
Browse ProSpec Recombinant Proteins

3 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005737 cytoplasm IEA--
GO:0005868 cytoplasmic dynein complex NAS11750132
GO:0005874 microtubule IEA--
About this table

DYNLRB2 for ontologies           About GeneDecksing



Antibodies for DYNLRB2: 
Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse Antibodies at Sigma-Aldrich
Browse R&D Systems for Antibodies
Browse OriGene Antibodies
GenScript Custom Superior Antibodies Services for DYNLRB2 
Browse antibodies at Epitomics

Assays for DYNLRB2: 
Browse Kits and Assays available from Millipore
Browse ELISAs at Sigma-Aldrich
OriGene Custom Immunoassay Development 
Browse OriGene Fluorogenic Cell Assay Kits 
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for DYNLRB2 
Browse Enzo Life Sciences for kits & assays
Uscn ELISAs and CLIAs for DYNLRB2 


(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

DYNLRB2 for domains           About GeneDecksing

2 InterPro domains/families:
 IPR016561 Dynein_light_roadblock-type
 IPR004942 Dynein_light-rel

Graphical View of Domain Structure for InterPro Entry Q8TF09

ProtoNet protein and cluster: Q8TF09

1 Blocks protein family: IPB004942 Roadblock/LC7 family

UniProtKB/Swiss-Prot: DLRB2_HUMAN, Q8TF09
Similarity: Belongs to the GAMAD family


(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: DLRB2_HUMAN, Q8TF09
Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are
thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic
dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules

Inhib.
RNA:
    
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich siRNA for DYNLRB2
Sigma-Aldrich shRNA for DYNLRB2
OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): DYNLRB2
OriGene shRNA RFP (see all 2): DYNLRB2
OriGene basic RS shRNA (see all 2): DYNLRB2
OriGene siRNA (see all 2): DYNLRB2
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of DYNLRB2 
miRNA:Sigma-Aldrich microRNA Mimics for DYNLRB2
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of DYNLRB2 
Search SABiosciences for Assays for microRNAs that regulate DYNLRB2

Gene
Editing:
Browse CompoZr Knockout ZFN at Sigma-Aldrich 

Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
Browse iPSC Reprogramming Factors at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: DYNLRB2
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: DYNLRB2
OriGene untagged cDNA clones in CMV expression vector: DYNLRB2
Browse 3'-UTR reporter clones for miRNA target validation 
Browse MicroRNA Expression Plasmids 
GenScript cDNA clone with any tag delivered in your preferred vector: DYNLRB2 
Browse Sino Biological Human cDNA Clones

Cell
Lines:
  
GenScript Custom overexpressing Cell Line Services for DYNLRB2 

2 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0003777 microtubule motor activity NAS11750132
GO:0005515 protein binding IEA--
About this table

DYNLRB2 for ontologies           About GeneDecksing


(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section


DYNLRB2 for pathways           About GeneDecksing

2 Millipore Pathways for DYNLRB2
    Cell cycle Spindle assembly and chromosome separation
Cytoplasmic microtubules

    SABiosciences Custom Pathway-Focused PCR Arrays for DYNLRB2 

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DYNLRB2

5 Interacting proteins for DYNLRB2 (ENSP000003029363) via UniProtKB, MINT, and/or STRING
InteractantInteraction Details
GeneCardExternal ID(s)
DYNC1LI2ENSP000002581983STRING: ENSP00000258198
DYNLL1ENSP000002425773STRING: ENSP00000242577
DYNLRB1ENSP000003639793STRING: ENSP00000363979
DYNC1I1ENSP000003201303STRING: ENSP00000320130
--ENSP000003517503STRING: ENSP00000351750
About this table

2 Gene Ontology (GO) biological process terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0006810 transport IEA--
GO:0007018 microtubule-based movement NAS11750132
About this table

DYNLRB2 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section
Browse Small Molecules at Sigma-Aldrich
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for DYNLRB2


(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib.
RNA:
     
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich siRNA for DYNLRB2
Sigma-Aldrich shRNA for DYNLRB2
OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): DYNLRB2
OriGene shRNA RFP (see all 2): DYNLRB2
OriGene basic RS shRNA (see all 2): DYNLRB2
OriGene siRNA (see all 2): DYNLRB2
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of DYNLRB2 
miRNA: Sigma-Aldrich microRNA Mimics for DYNLRB2
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of DYNLRB2 
Search SABiosciences for Assays for microRNAs that regulate DYNLRB2
Clones: Browse FLAG tag genes at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: DYNLRB2
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: DYNLRB2
OriGene untagged cDNA clones in CMV expression vector: DYNLRB2
Browse 3'-UTR reporter clones for miRNA target validation 
Browse OriGene MicroRNA Expression Plasmids 
GenScript cDNA clone with any tag delivered in your preferred vector: DYNLRB2 
Primers: OriGene genome-wide validated SYBR primer pairs: DYNLRB2
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for DYNLRB2: PPH10744A

REFSEQ mRNAs for DYNLRB2 gene: 

NM_130897.1  

Additional cDNA sequence: 

AF125108.1 BC035232.1 BC054892.1 

5 DOTS entries:

DT.97778290  DT.95154196  DT.100019166  DT.75196573  DT.120656292 

24 AceView cDNA sequences:

AA435968 AA446298 BC054892 AI826656 BX340151 AI023522 BQ109457 AA446025 
AI026825 AA769674 CD676360 AA719152 AA872500 BC035232 BI830575 AA961187 
AA300900 NM_130897 AF125108 BM668600 AA928442 BP370813 AW959427 AL043981 

highest scoring ESTs for DYNLRB2:

AA435968 AA446025 AA446298 AA719152 AA769674 AA872500 AF125108 AI023522 AI026825 AL043981 

Unigene Cluster for DYNLRB2:

Dynein, light chain, roadblock-type 2
Hs.98849  [show with all ESTs]
Unigene Representative Sequence: BC035232


GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for DYNLRB2

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b
SP1:                                -                     
SP2:        -     -           -     -                     
SP3:                          -     -                     
SP4:                          -                           

About this scheme

ECgene alternative splicing isoforms for DYNLRB2
2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000338542 ENST00000305904(uc002ffo.2 uc002ffp.2 uc002ffq.2)


(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

DYNLRB2 expression in normal and diseased human tissues

1  / 2  / 3

3 probe-sets matching DYNLRB2 gene

Affymetrix
probe-set
Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
47635_at2, 3 U95-B 1 0.81 1.00 1.00 1.00 AA719152 0.80 1.00 0.91 1
238116_at2, 3 U133-B 1 0.73 1.00 -- -- AW959427 0.80 1.00 0.91 1
238116_at2 U133Plus2 1 0.73 1.00 -- -- -- -- -- -- --
About this table

DYNLRB2 for expression           About GeneDecksing

Data from Genenote  (Publications) and GNF BioGPS
    About these images
DYNLRB2 gene expression
DYNLRB2 gene electronic northern expression
DYNLRB2 gene sage expression
About these images

CGAP SAGE TAG: AGTATTAAAA

SOURCE GeneReport for Unigene cluster: Hs.98849

UniProtKB/Swiss-Prot: DLRB2_HUMAN, Q8TF09
Tissue specificity: High expression in heart, brain, placenta, skeletal muscle, prostate and small intestine; moderate
in kidney, pancreas, spleen, testis, ovary and colon; low in lung, liver, thymus and leukocyte

Primers: OriGene genome-wide validated SYBR primer pairs: DYNLRB2
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for DYNLRB2: PPH10744A
    SABiosciences Custom PCR Arrays for DYNLRB2 


(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for DYNLRB2 gene from 5/14 species (see all 14)
Organism Gene Locus Description Human
Similarity
NCBI accessions
dog
(Canis familiaris)
LOC4796361   -- similar to dynein, cytoplasmic, light chain 2B 92.01(n)
98.96(a)
479636  XM_536771.2  XP_536771.1 
chimpanzee
(Pan troglodytes)
DYNLRB21   -- dynein, light chain, roadblock-type 2 100(n)
100(a)
454263  XM_511124.2  XP_511124.2 
cow
(Bos taurus)
DYNLRB21   -- dynein, light chain, roadblock-type 2 93.4(n)
98.96(a)
768062  NM_001077119.1  NP_001070587.1 
rat
(Rattus norvegicus)
Dynlrb21   -- dynein light chain roadblock-type 2 85.42(n)
97.92(a)
361415  XM_341694.3  XP_341695.2 
mouse
(Mus musculus)
Dynlrb21 , 5 8 (63.07 cM)5
dynein light chain roadblock-type 21, 5 88.19(n)1
97.92(a)1
754651  NM_029297.11  NP_083573.11 
 AI4258935  AI8359955  (see all 9)
About this table        Species with no ortholog for DYNLRB2

ENSEMBL Gene Tree for DYNLRB2 (if available)

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
Paralogs for DYNLRB2 gene
DYNLRB12  

DYNLRB2 for paralogs           About GeneDecksing



(SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

10/172 NCBI SNPs in DYNLRB2 are shown (see all 172)
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidChr 16 posSequenceRecsAA
Chg
TypeMoreRecsAllele
freq
PopTotal
sample
More
----------
rs42586301,2
C,F,A,H,80579205(+) cagaaC/Aaaata 1 -- int19Minor allele frequency- A:0.18NA WA 202
rs42730481,2
C,F,H,80579300(+) agactA/Gtttag 1 -- int111Minor allele frequency- G:0.03NA WA 206
rs44322761,2
C,H,80582517(+) gggaaG/Actgag 1 -- int17Minor allele frequency- A:0.00NA WA 16
rs44580051,2
C,F,A,H,80573225(+) CAACTT/CAGCCA 1 -- ng5118Minor allele frequency- C:0.36NS EA NA WA 1056
rs45301571,2
C,A,H,80582492(+) tgggtG/Tcctct 1 -- int16Minor allele frequency- T:0.00NA 14
rs45332961,2
C,F,A,H,80573244(+) GTAAAC/GACCTA 1 -- ng5121Minor allele frequency- G:0.35NS EA NA WA 1208
rs45614801,2
C,F,H,80579098(+) atctaC/Taattt 1 -- int119Minor allele frequency- T:0.02NS EA NA WA 996
rs45677281,2
C,F,A,80573484(+) ATATAT/CAGATT 1 -- ng5112Minor allele frequency- C:0.32EA NA WA 434
rs45911581,2
C,H,80578788(+) tctgtT/Ctgtct 1 -- int17Minor allele frequency- C:0.11NA WA 62
rs45942671,2
C,A,80582362(+) ctcacA/Gcctgt 1 -- int12Minor allele frequency- G:0.25NA 4
About this table

HapMap Linkage Disequilibrium images for DYNLRB2 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for DYNLRB2: --

Search QIAGEN SeqTarget long-range PCR primers for resequencing for DYNLRB2 

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section

DYNLRB2 for disorders           About GeneDecksing

OMIM: 607168

Human Genome Epidemiology (HuGE) Navigator: DYNLRB2 (2 documents)

Export disorders and mutations for DYNLRB2 gene to outside databases

(Possibly Related Articles in Doctor's Guide)
About This Section
  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
About This Section

8 PubMed articles for DYNLRB2 gene integrated from 7 sources:
(articles sorted by number of sources associating them with DYNLRB2)
  1. Identification of two novel human dynein light chain genes, DNLC2A and DNLC2B, and their expression changes in hepatocellular carcinoma tissues from 68 Chinese patients. (PubMed id 11750132)1, 2, 3, 7 Jiang J.... Zhao S. (2001)
  2. Cytoplasmic dynein nomenclature. (PubMed id 16260502)1, 3 Pfister K.K....Vallee R.B. (2005)
  3. The roadblock light chain binds a novel region of the cytoplasmic Dynein intermediate chain. (PubMed id 12077152)1, 2 Susalka S.J....Pfister K.K. (2002)
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
  5. Fine mapping and association studies of a high-densit y lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian su bjects. (PubMed id 19844255)1 Dastani Z....Genest J. (2010)
  6. Requirement of a dynein light chain in TGFbeta/Smad3 signaling. (PubMed id 19711352)1 Jin Q....Mulder K.M. (2009)
  7. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1 Gevaert K.... Vandekerckhove J. (2003)
  8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 83657 HGNC: 15467 AceView: DNCL2B Ensembl:ENSG00000168589 euGenes: HUgn83657
ECgene: DYNLRB2 H-InvDB: DYNLRB2

(According to HUGE)
About This Section
  --

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
  --

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from XenneX, Inc.)
About This Section
Patent Information for DYNLRB2 gene:
Search GeneIP for patents involving DYNLRB2

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
About This Section

 Millipore Custom Antibody & Bulk Services
 Millipore Preclinical / Clinical Development Services
 Millipore Immunoassay Services
 Millipore Target Screening & Profiling Services

 Predesigned and custom siRNAs for DYNLRB2 Browse antibodies at Sigma-Aldrich
 Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
 Lentivirus-delivered shRNAs for DYNLRB2 microRNA Mimics for DYNLRB2
 "Your Favorite Gene" Pathways and Molecular Interaction Networks Browse Nano Scale siRNA at Sigma-Aldrich
 Browse iPSC Reprogramming Factors at Sigma-Aldrich Browse small molecules at Sigma-Aldrich
 Browse FLAG tag genes at Sigma-Aldrich Browse ELISAs at Sigma-Aldrich
 Browse microRNA Target Validation Systems at Sigma-Aldrich Browse CompoZr Knockout ZFN at Sigma-Aldrich
feedback
  
 Antibodies   Cell Culture Products  
 ELISAs   Flow Cytometry Kits  
 Primer Pairs   Kinase Activity Assays/Reagents  
 ELISpot Kits/Development Modules   TFB/Immunoprecipitation Assays  
 Apoptosis Detection Kits/Reagents   Protease Activity Assays/Reagents  
 DNA Damage/Repair Kits/Reagents   Multiplex/Array Assay Kits/Reagents  
 Cell Selection/Detection Kits/Reagents   ELISA/Assay Development Kits/Reagents  
 Phosphatase Activity Assays/Reagents   Recombinant/Natural Proteins  
 Tagged/untagged cDNA clones
 Validated SYBR primer pairs
 Purified proteins from HEK293T cells
 Lysates
 Western blot validated antibodies
 shRNA in GFP-retroviral vector
 siRNA
 Custom Immunoassay Development
 Fluorogenic Cell Assay Kits
 miRNA Primers for qPCR Assays
 3' UTR Clones for miRNA Target Studies
 miRNA Expression Plasmids

 
 
 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of DYNLRB2
 Search QIAGEN SeqTarget long-range PCR primers for resequencing for DYNLRB2
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of DYNLRB2
 GenScript Custom Purified and Recombinant Proteins Services for DYNLRB2 GenScript cDNA clones with any tag delivered in your preferred vector for DYNLRB2
 GenScript Custom Assay Services for DYNLRB2 GenScript Custom Superior Antibodies Services for DYNLRB2
 GenScript Custom overexpressing Cell Line Services for DYNLRB2 CloneReady with Over 120,000 Genes
 Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
 Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
 Custom Peptide Services
 Search for Antibodies & Assays

 Regulatory tfbs in DYNLRB2 promoter
 Search Chromatin IP Primers for DYNLRB2
 RT2 qPCR Primer Assay for DYNLRB2
 Search GNC Networks for DYNLRB2
 Search for Assays for microRNAs that regulate DYNLRB2
 SABiosciences Custom PCR Arrays for DYNLRB2
 Search Tocris compounds for DYNLRB2
 Browse Sino Biological Proteins and Antibodies
 Browse Sino Biological cDNA Clones
 Antibodies/Proteins Production Services
 Rabbit Monoclonal Antibody Platform
 Bulk Purchasing
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
 Novus Biologicals
 Novus Tissue Slides
 Browse antibodies at Epitomics
 Browse ProSpec Recombinant Proteins

 ELISAs and CLIAs for DYNLRB2
       

GeneCards Homepage - Last full update: 30 Dec 2010 - Incremental updates: 9 Jan 2011 , 10 Jan 2011

View Random Gene

Category
GIFtS Group
The GeneCards human gene database gene index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

DYNLRB2 gene at Home site.
hostname: www-ab3 db genecards_305 index build: 81e solr: 1.4