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ENSG00000211962 Gene

protein-coding   GIFtS: 12

GC14M106967          (predicted)

symbol from the Ensembl Database
NOT approved by the HUGO Gene Nomenclature Committee (HGNC).
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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External Ids:    Ensembl: ENSG000002119627   UniProtKB: P017433   

Export aliases for ENSG00000211962 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

  --

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for ENSG00000211962
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for ENSG00000211962

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Ensembl cytogenetic band:  14q32.33   

ENSG00000211962 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ENSG00000211962 gene location

GeneLoc gene densities for chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M106967:  view genomic region     (about GC identifiers)

Start:
106,967,049 bp from pter
End:
106,967,788 bp from pter
Size:
740 bases
Orientation:
minus strand
ENSG00000211962 has overlapping exons with:
ENSG00000211947 ENSG00000238275 IGHVII-40-1 ENSG00000253209 ENSG00000211958 ENSG00000211939 ENSG00000211979 ENSG00000225200 ENSG00000253462

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
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UniProtKB/Swiss-Prot: HV102_HUMAN, P01743 (See protein sequence)
Recommended Name: Ig heavy chain V-I region HG3 precursor  
Size: 117 amino acids; 12946 Da

Explore the universe of human proteins at neXtProt for ENSG00000211962: NX_P01743 



ENSEMBL proteins: 
ENSP00000375031 


Human Recombinant Proteins 
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1 Gene Ontology (GO) cellular component term (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005576 extracellular region ----
About this table

ENSG00000211962 for ontologies           About GeneDecksing



Antibodies for ENSG00000211962: 
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Assays for ENSG00000211962: 
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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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ENSG00000211962 for domains           About GeneDecksing

4 InterPro domains/families:
 IPR007110 Ig-like
 IPR003596 Ig_V-set_sub
 IPR013783 Ig-like_fold
 IPR013106 Ig_V-set

Graphical View of Domain Structure for InterPro Entry P01743

ProtoNet protein and cluster: P01743

1 Blocks protein family: IPB003596 Immunoglobulin V-type

UniProtKB/Swiss-Prot: HV102_HUMAN, P01743
Similarity: Contains 1 Ig-like (immunoglobulin-like) domain


(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI ,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
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Inhib.
RNA:
    
Browse for Gene Knock-down Tools from Millipore
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miRNA:Browse microRNA Mimics at Sigma-Aldrich
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of ENSG00000211962 
Search SABiosciences for Assays for microRNAs that regulate ENSG00000211962

Gene
Editing:
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Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
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Cell
Lines:
  
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1 Gene Ontology (GO) molecular function term (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0003823 antigen binding ----
About this table

ENSG00000211962 for ontologies           About GeneDecksing


(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
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    SABiosciences Custom Pathway-Focused PCR Arrays for ENSG00000211962 

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ENSG00000211962

1 Gene Ontology (GO) biological process term (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0006955 immune response ----
About this table

ENSG00000211962 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section
Browse Small Molecules at Sigma-Aldrich
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ENSG00000211962


(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build ; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib.
RNA:
     
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Browse siRNA at Sigma-Aldrich
Browse shRNA at Sigma-Aldrich
Browse OriGene 29mer shRNA kits
Browse OriGene siRNA
Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of ENSG00000211962 
miRNA: Browse microRNA Mimics at Sigma-Aldrich
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of ENSG00000211962 
Search SABiosciences for Assays for microRNAs that regulate ENSG00000211962
Clones: Browse FLAG tag genes at Sigma-Aldrich
Browse OriGene untagged/tagged cDNA clones in CMV expression vector
Browse 3'-UTR reporter clones for miRNA target validation 
Browse OriGene MicroRNA Expression Plasmids 
GenScript Custom cDNA clone Services for ENSG00000211962 
Primers:Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs 
Search SABiosciences RT2 qPCR Primer Assays for ENSG00000211962


GeneLoc Exon Structure

1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000390622

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build ), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

ENSG00000211962 expression in normal and diseased human tissues

Data from GNF    About these images

ENSG00000211962 gene expression
ENSG00000211962 gene electronic northern expression
ENSG00000211962 gene sage expression
About these images

CGAP SAGE TAG: --
Primers:Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs 
Search SABiosciences RT2 qPCR Primer Assays for ENSG00000211962
    SABiosciences Custom PCR Arrays for ENSG00000211962 


(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI , with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section
ENSEMBL Gene Tree for ENSG00000211962 (if available)

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
Paralogs for ENSG00000211962 gene
ENSG000002119682  IGHV1OR15-92  ENSG000002119352  ENSG000002119612  LOC1002904152  ENSG000002119452  ENSG000002119662  IGHV1OR21-12  
LOC1001338622  ENSG000002119392  ENSG000002119792  ENSG000002119342  

ENSG00000211962 for paralogs           About GeneDecksing


Pseudogenes
4 related pseudogenes



(SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
Search QIAGEN SeqTarget long-range PCR primers for resequencing for ENSG00000211962 

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section
  --

(Possibly Related Articles in Doctor's Guide)
About This Section
  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
About This Section

1 PubMed article for ENSG00000211962 gene integrated from 7 sources:
(articles sorted by number of sources associating them with ENSG00000211962)
  1. Evolutionary aspects of immunoglobulin heavy chain variable region (VH) gene subgroups. (PubMed id 6298778)2 Rechavi G.... Givol D. (1983)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Ensembl:ENSG00000211962

(According to HUGE)
About This Section
  --

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
  --

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from XenneX, Inc.)
About This Section
Patent Information for ENSG00000211962 gene:
Search GeneIP for patents involving ENSG00000211962

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
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