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FAM183A Gene

protein-coding   GIFtS: 29

GC01P041733
family with sequence similarity 183, member A
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
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Aliases &
Descriptions
for FAM183A gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases & Descriptions
family with sequence similarity 183, member A1 2     OTTHUMP000002041152
hCG231771 2     OTTHUMP000002041162
LOC4405851     OTTHUMP000002041172
OTTHUMP000002041182     

External Ids:    HGNC: 343471   Entrez Gene: 4405852   Ensembl: ENSG000001869737   UniProtKB: A6NL823   

Export aliases for FAM183A gene to outside databases

Previous GC identifers: GC01P043383 GC01P043610


Summaries
for FAM183A gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
  --

Genomic Views
for FAM183A gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for FAM183A
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for FAM183A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for FAM183A 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p34.2   Ensembl cytogenetic band:  1p34.2   HGNC cytogenetic band: 1p34.2

FAM183A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM183A gene location

GeneLoc gene densities for chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P041733:  view genomic region     (about GC identifiers)

Start:
 41,733,354 bp from pter
End:
 41,741,829 bp from pter
Size:
 8,476 bases
Orientation:
 plus strand

1 alternative location:
Chr1+ 43,610,029-43,622,067     
RefSeq DNA sequence:
NC_000001.10  NT_032977.9  

Proteins
for FAM183A gene

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section
UniProtKB/Swiss-Prot: F183A_HUMAN, A6NL82 (See protein sequence)
Recommended Name: Protein FAM183A  
Size: 134 amino acids; 15996 Da
Secondary accessions: B7ZBL8

Explore the universe of human proteins at neXtProt for FAM183A: NX_A6NL82 

REFSEQ proteins: NP_001094846.2  

ENSEMBL proteins: 
ENSP00000386318 ENSP00000387249 ENSP00000334415 ENSP00000387244 ENSP00000387018 ENSP00000387254 


Human Recombinant Proteins 
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Antibodies for FAM183A: 
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Assays for FAM183A: 
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Protein Domains/
Families
for FAM183A gene

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ProtoNet protein and cluster: A6NL82

UniProtKB/Swiss-Prot: F183A_HUMAN, A6NL82
Similarity: Belongs to the FAM183 family


Gene Function
for FAM183A gene

(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section
Inhib.
RNA:    		Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich siRNA for FAM183A
Sigma-Aldrich shRNA for FAM183A
OriGene 29mer shRNA kits in GFP-retroviral vector (see all 5): FAM183A
OriGene shRNA RFP (see all 5): FAM183A
OriGene basic RS shRNA (see all 5): FAM183A
OriGene siRNA (see all 5): FAM183A
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of FAM183A 
miRNA:Browse microRNA Mimics at Sigma-Aldrich
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of FAM183A 
Search SABiosciences for Assays for microRNAs that regulate FAM183A

Gene
Editing:		Browse CompoZr Knockout ZFN at Sigma-Aldrich 

Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
Browse iPSC Reprogramming Factors at Sigma-Aldrich
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: FAM183A
OriGene untagged cDNA clones in CMV expression vector: FAM183A
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Cell
Lines:  		GenScript Custom overexpressing Cell Line Services for FAM183A 


Pathways & Interactions
for FAM183A gene

(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section

    SABiosciences Custom Pathway-Focused PCR Arrays for FAM183A 

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM183A

Drugs & Compounds
for FAM183A gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section
Browse Small Molecules at Sigma-Aldrich
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for FAM183A


Transcripts
for FAM183A gene

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section
Inhib.
RNA:     		Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich siRNA for FAM183A
Sigma-Aldrich shRNA for FAM183A
OriGene 29mer shRNA kits in GFP-retroviral vector (see all 5): FAM183A
OriGene shRNA RFP (see all 5): FAM183A
OriGene basic RS shRNA (see all 5): FAM183A
OriGene siRNA (see all 5): FAM183A
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of FAM183A 
miRNA: Browse microRNA Mimics at Sigma-Aldrich
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of FAM183A 
Search SABiosciences for Assays for microRNAs that regulate FAM183A
Clones: Browse FLAG tag genes at Sigma-Aldrich
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: FAM183A
OriGene untagged cDNA clones in CMV expression vector: FAM183A
Browse 3'-UTR reporter clones for miRNA target validation 
Browse OriGene MicroRNA Expression Plasmids 
GenScript Custom cDNA clone Services for FAM183A 
Primers: OriGene genome-wide validated SYBR primer pairs: FAM183A
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for FAM183A: PPH66845A

REFSEQ mRNAs for FAM183A gene: 

NM_001101376.2  

Additional cDNA sequence: AK309744.1 

9 DOTS entries:

DT.205763  DT.450422  DT.75101928  DT.100745604  DT.121381906  DT.92417245  DT.95154830  DT.95149694 
DT.99976962 

24/44 AceView cDNA sequences (see all 44):

BM976667 AI681257 R64685 AW029496 AW138367 BF477758 AI469340 BQ025739 
AA833578 BU689027 AI685578 AA431291 BF061370 CD239034 AA431652 AI201524 
CD238494 AI635061 CD239517 AI375550 BU676445 BM926539 BV189645 AI611120 

Unigene Cluster for FAM183A:

Family with sequence similarity 183, member A
Hs.657614  [show with all ESTs]
Unigene Representative Sequence: AK309744


GeneLoc Exon Structure

7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000409337 ENST00000410048 ENST00000335282 ENST00000481753 ENST00000409706(uc009vwn.1)
ENST00000410025(uc009vwo.2) ENST00000409396

Expression
for FAM183A gene

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

FAM183A expression in normal and diseased human tissues

1 Data from GNF BioGPS
    About these images

FAM183A gene expression
FAM183A gene electronic northern expression
FAM183A gene sage expression
About these images

CGAP SAGE TAG: ACCGCAGGCT

SOURCE GeneReport for Unigene cluster: Hs.657614
Primers: OriGene genome-wide validated SYBR primer pairs: FAM183A
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for FAM183A: PPH66845A
    SABiosciences Custom PCR Arrays for FAM183A 


Orthologs
for FAM183A gene

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section
Orthologs for FAM183A gene from 3 species
Organism Gene Locus Description Human
Similarity		 NCBI accessions
chimpanzee
(Pan troglodytes)		 LOC4565111   -- hypothetical LOC456511 100(n)
100(a)		 456511  XM_513097.1  XP_513097.1 
chicken
(Gallus gallus)		 LOC4245571   -- hypothetical gene supported by BX932049 62.87(n)
56.1(a)		 424557  XM_422395.2  XP_422395.1 
zebrafish
(Danio rerio)		 LOC7928341   -- similar to predicted protein 54.81(n)
48.08(a)		 792834  XM_001332144.2  XP_001332180.2 
About this table        Species with no ortholog for FAM183A

ENSEMBL Gene Tree for FAM183A (if available)

Paralogs
for FAM183A gene

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
Paralogs for FAM183A gene
FAM183B2  

FAM183A for paralogs           About GeneDecksing



Genomic Variants
for FAM183A gene

(SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

10/144 NCBI SNPs in FAM183A are shown (see all 144)
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidChr 1 posSequenceRecsAA
Chg		TypeMoreRecsAllele
freq		PopTotal
sample		More
----------
rs4750931,2
C,F,O,A,43616337(+) AGTGAG/CTGCCA 1 -- int120Minor allele frequency- C:0.12MN NS EA NA WA 1716
rs5196661,2
C,A,43613786(+) AGGGCG/TAGAGC 1 -- int14Minor allele frequency- T:0.24MN NA 260
rs5846721,2
C,F,43615668(+) CTCACG/ACTCAT 1 -- int17Minor allele frequency- A:0.14NS EA NA WA 544
rs5898191,2
C,F,O,A,43621759(+) ATTCCG/TCAATG 1 -- int111Minor allele frequency- T:0.26MN NS EA NA WA 1096
rs6037861,2
C,F,A,H,43622560(-) GGCTCA/GTGCCT 1 -- ng3111Minor allele frequency- G:0.30MN NS EA NA WA 637
rs6102001,2
C,F,O,A,43616753(+) ACTAAC/TGTTCC 1 -- int1105Minor allele frequency- T:0.31NS EA PA EU CA WA NA 6792
rs6128671,2
C,A,H,43617327(+) GTGAGA/GGAGGA 1 -- int1 trp37Minor allele frequency- G:0.36MN EA WA NA 330
rs6142401,2
C,F,A,43617657(+) TATATG/TAAGGA 1 -- int15Minor allele frequency- T:0.19MN NS NA EA WA 466
rs6369691,2
C,F,A,43616426(+) TTTTTT/GTCTAG 1 -- int1 trp36Minor allele frequency- G:0.03MN NS EA WA 652
rs6539071,2
C,F,O,A,H,43612105(+) TAAAAG/ATAACC 1 -- ng5115Minor allele frequency- A:0.36MN NS EA NA WA 871
About this table

HapMap Linkage Disequilibrium images for FAM183A (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for FAM183A: --

QIAGEN SeqTarget long-range PCR primers for resequencing FAM183A 

Disorders & Mutations
for FAM183A gene

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section
   --

Medical News
for FAM183A gene

(Possibly Related Articles in Doctor's Guide)
About This Section
   --

Publications
for FAM183A gene

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
About This Section

2 PubMed articles for FAM183A gene integrated from 7 sources:
(articles sorted by number of sources associating them with FAM183A)
  1. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
  2. The sequence of the human genome. (PubMed id 11181995)1, 3 Venter J.C.... Zhu X. (2001)

External Searches for FAM183A gene

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
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  Query String
PubMed
OMIM
NCBI Bookshelf
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Genome Databases showing FAM183A gene

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 440585 HGNC: 34347 AceView: LOC440585 Ensembl:ENSG00000186973 euGenes: HUgn440585
ECgene: FAM183A H-InvDB: FAM183A

Other Databases showing FAM183A gene

(According to HUGE)
About This Section
   --

Specialized Databases showing FAM183A gene

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
   --

Intellectual Property
for FAM183A gene

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from XenneX, Inc.)
About This Section
Patent Information for FAM183A gene:
Search GeneIP for patents involving FAM183A

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



Products
for FAM183A gene

(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
About This Section

 Millipore Custom Antibody & Bulk Services
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 miRNA Expression Plasmids

 		 
 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of FAM183A
 SeqTarget long-range PCR primers for resequencing FAM183A
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for FAM183A
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of FAM183A
 GenScript Custom Purified and Recombinant Proteins Services for FAM183A GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for FAM183A
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 Browse ELISAs and CLIAs at Uscn
       

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