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Aliases & Descriptionsfor FAM190B gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section Aliases & Descriptions family with sequence similarity 190, member B1 2 bA486O22.12 KIAA11281 2 3 FLJ142622 Gcap142 granule cell antiserum positive 142 FLJ258092 Protein GCAP14 homolog3
Export aliases for FAM190B gene to outside databases Previous GC identifer: GC10P086079
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Summariesfor FAM190B gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section --
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Genomic Viewsfor FAM190B gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60) ,
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences )About This Section Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for FAM190B Other transcription factors Search SABiosciences Chromatin IP Primers for FAM190B Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for FAM190B
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 10q23.1 Ensembl cytogenetic band: 10q23.1 HGNC cytogenetic band: 10q23.1 FAM190B Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 10 GeneLoc Exon Structure
GeneLoc location for GC10P079933: view genomic region
(about GC identifiers )
Start:
79,933,826 bp from pter
End:
80,123,654 bp from pter
Size:
189,829 bases
Orientation:
plus strand
1 alternative location : Chr 10+ 86,088,342-86,278,276
RefSeq DNA sequence: NC_000010.10 NT_030059.13
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Proteinsfor FAM190B gene
(According to
1 UniProtKB ,
neXtProt ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological , and/or
ProSpec ,
Biochemical Assays by
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene ,
Antibodies by
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals , and/or
Epitomics )
About This Section UniProtKB/Swiss-Prot: F190B_HUMAN, Q9H7U1 (See
protein sequence )Recommended Name: Protein FAM190B Size : 834 amino acids; 93548 Da
Sequence caution : Sequence=AAG44473.1; Type=Frameshift; Positions=187, 240, 244; Sequence=AAH30528.1; Type=Erroneousinitiation; Note=Translation N-terminally extended; Sequence=CAI40902.1; Type=Erroneous gene model prediction;
Secondary accessions : B4DQU9 B7WPE8 D3DWE2 Q8N6E9 Q9H2S0 Q9ULU1Alternative splicing : 3 isoforms : Q9H7U1-1 Q9H7U1-2 Q9H7U1-3 Explore the universe of human proteins at neXtProt for FAM190B: NX_Q9H7U1 Post-translational modifications:
View phosphorylation sites using PhosphoSite 2
REFSEQ proteins: NP_061872.2 ENSEMBL proteins: ENSP00000224756 ENSP00000353068 ENSP00000361160 Human Recombinant Proteins 1 Gene Ontology (GO) cellular component term (GO ID links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0016021 integral to membrane
-- --
About this table
FAM190B for ontologies About GeneDecksing Antibodies for FAM190B: Assays for FAM190B:
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Protein
Domains/ Familiesfor FAM190B gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section ProtoNet protein and cluster: Q9H7U1
UniProtKB/Swiss-Prot: F190B_HUMAN, Q9H7U1 Similarity : Belongs to the FAM190 family
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Gene Functionfor FAM190B gene
(According to UniProtKB ,
IUBMB ,and/or
Genatlas , Animal models from MGI Dec 24 2010,
shRNA from
OriGene ,
Sigma-Aldrich ,
RNAi from
Millipore ,
siRNAs from
Sigma-Aldrich ,
OriGene ,
Qiagen ,
Super-pooled esiRNAs from Sigma-Aldrich ,
microRNA from Sigma-Aldrich ,
Qiagen ,
SABiosciences ,
Clones from Millipore ,
Sigma-Aldrich ,
OriGene ,
GenScript ,
Sino Biological ,
Cell Lines from GenScript ,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene .)
About This Section
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Pathways & Interactionsfor FAM190B gene
(Pathways according to
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
PCR Arrays from
SABiosciences ,
Proteins Network according to
SABiosciences ,
Sigma-Aldrich ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene) .
About This Section SABiosciences Custom Pathway-Focused PCR Arrays for FAM190B Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM190B 5/7 Interacting proteins for FAM190B (Q9H7U1 2 ) via UniProtKB, MINT, and/or STRING (see all 7 )About this table 1 Gene Ontology (GO) biological process term (GO ID links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0007186 G-protein coupled receptor protein signaling pathway
-- --
About this table
FAM190B for ontologies About GeneDecksing
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Drugs & Compoundsfor FAM190B gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
About This Section Browse Tocris compounds for FAM190B
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Transcriptsfor FAM190B gene (GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
Millipore ,
siRNAs from
Sigma-Aldrich ,
OriGene ,
Qiagen ,
Super-pooled esiRNAs from Sigma-Aldrich ,
shRNA from
Sigma-Aldrich ,
OriGene ,
microRNA from Sigma-Aldrich ,
Qiagen ,
SABiosciences ,
Tagged/untagged cDNA clones from
OriGene ,
Sigma-Aldrich ,
GenScript ,
Primers from
OriGene and/or
SABiosciences )About This Section REFSEQ mRNAs for FAM190B gene: NM_018999.2
Additional cDNA sequence: AB032954.1 AF241785.1 AK024324.1 AK098675.1 AK294321.1 AK298966.1 BC020910.1 BC030528.1 BX640691.1 U90912.1
11 DOTS entries : DT.415981 DT.95277659 DT.95277662 DT.100789582 DT.91759374 DT.100789581 DT.91759377 DT.95277661
DT.121212840 DT.121212898 DT.95110984 24/53 AceView cDNA sequences (see all 53 ):
AA694185 AA662191 BI829315 AI927019 BP362870 BU632221 AI678126 BC030528 BP370871 AI001725 T39163 AA424126 AW027699 W77829 BF173466 BQ429698 AA424038 BP369764 AK024324 AL707865 BI772058 AA432090 AA446776 BU599757 Unigene Cluster for FAM190B:
Family with sequence similarity 190, member B Hs.461988 [show with all ESTs ] Unigene Representative Sequence: NM_018999 GeneLoc Exon Structure 5 Alternative Splicing Database (ASD) splice patterns (SP) for FAM190B ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b · 13c · 13d SP1 :         -   -           -                   SP2 :                 -   -   -         -           SP3 :                     -         -           SP4 :                             -           SP5 :                                      
About this scheme ECgene alternative splicing isoforms for FAM190B 9 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000494586 ENST00000493409 ENST00000480006 ENST00000224756 (uc001kdh.1 uc010qme.1 )ENST00000466105 ENST00000359979 (uc001kdg.1 ) ENST00000498300 ENST00000494144 ENST00000372088 (uc010qmd.1 uc001kdi.1 )
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Expression for FAM190B gene
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Primers from
OriGene and/or
SABiosciences
)
About This Section FAM190B expression in normal and diseased human tissues 1 / 2
11 probe-sets matching FAM190B gene
Affymetrix probe-set
Array
GeneAnnot data
GeneNote data
GeneTide data
# genes
Sensitivity
Specificity
Correlation
Length
Gb_Accession
Consensus
Uniqueness
Score
Rank
51854_at2
U95-B
1
1.00
1.00
0.97
0.71
--
--
--
--
--
56579_at2
U95-B
1
0.88
1.00
0.02
0.54
--
--
--
--
--
74676_at2
U95-E
1
0.81
1.00
0.94
1.42
--
--
--
--
--
48324_at2
U95-B
1
0.81
1.00
0.95
1.07
--
--
--
--
--
37617_at2
U95-A
1
0.81
1.00
0.86
1.30
--
--
--
--
--
209379_s_at2
U133-A
1
1.00
1.00
--
--
--
--
--
--
--
209378_s_at2
U133-A
1
0.73
1.00
--
--
--
--
--
--
--
209379_s_at2
U133Plus2
1
1.00
1.00
--
--
--
--
--
--
--
1554132_a_at2
U133Plus2
1
1.00
1.00
--
--
--
--
--
--
--
209378_s_at2
U133Plus2
1
0.73
1.00
--
--
--
--
--
--
--
1554131_at2
U133Plus2
2
0.64
0.88
--
--
--
--
--
--
--
About this table
FAM190B for expression About GeneDecksing Data from
Genenote  
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: TTTTAATCTT SOURCE GeneReport for Unigene cluster: Hs.461988 SABiosciences Custom PCR Arrays for FAM190B
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Orthologsfor FAM190B gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
About This Section
Orthologs for FAM190B gene from 4 species
Organism
Gene
Locus
Description
Human Similarity
NCBI accessions
dog (Canis familiaris)
LOC4792681
--
similar to granule cell antiserum positive 14
93.11(n) 90.62(a)
479268 XM_536410.2 XP_536410.2
mouse (Mus musculus)
Gcap145
14 (21.29 cM)
granule cell antiserum positive 14
--
L10901
chicken (Gallus gallus)
KIAA11281
--
KIAA1128
71.62(n) 62.32(a)
423606 XM_421492.2 XP_421492.2
tropical clawed frog (Silurana tropicalis)
Str.171402
--
Transcribed sequences
76.19(n)
BX769556.1
About this table Species with no ortholog for FAM190B ENSEMBL Gene Tree for FAM190B (if available)
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Paralogsfor FAM190B gene (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section --
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Genomic Variantsfor FAM190B gene (SNPs according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Resequencing Primers from Qiagen )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Chr 10 pos Sequence Recs AA Chg Type More Recs Allele freq Pop Total sample More
About this table HapMap Linkage Disequilibrium images for FAM190B (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for FAM190B: --
QIAGEN SeqTarget long-range PCR primers for resequencing FAM190B
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Disorders & Mutationsfor FAM190B gene
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
LSDB, HGMD, GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
FAM190B for disorders About GeneDecksing Human Genome Epidemiology (HuGE) Navigator: FAM190B (0 documents) Export disorders and mutations for FAM190B gene to outside databases
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Medical Newsfor FAM190B gene (Possibly Related Articles in
Doctor's Guide )
About This Section --
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Publicationsfor FAM190B gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 UniProtKB/TrEMBL , and/or
7 Novoseek )
About This Section 10 PubMed articles for FAM190B gene integrated from 7 sources : (articles sorted by number of sources associating them with FAM190B) Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PubMed id 10574461) 1 , 2 , 3 Hirosawa M.... Ohara O. (1999) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614) 1 Rose J.E....Uhl G.R. (2010) Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. (PubMed id 18083107) 2 Rikova K....Comb M.J. (2007) A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451) 1 Grupe A....Goate A. (2006) A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070) 1 Stelzl U.... Wanker E.E. (2005) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 2 Gerhard D.S....Malek J. (2004) The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054) 2 Deloukas P.... Rogers J. (2004) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002) A "double adaptor" method for improved shotgun library construction. (PubMed id 8619474) 1 Andersson B.... Gibbs R.A. (1996)
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External Searches for FAM190B gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing FAM190B gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
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Other Databases showing FAM190B gene
(According to HUGE )
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Specialized Databases showing FAM190B gene (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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About This Section Patent Information for FAM190B gene: Search GeneIP for patents involving FAM190B GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor FAM190B gene (Antibodies, recombinant proteins, and assays by Millipore , Sigma-Aldrich , R&D Systems , Qiagen , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Epitomics , ProSpec , Uscn , Clones available from Millipore , Sigma-Aldrich , OriGene , GenScript , Sino Biological , PCR Arrays from SABiosciences , Drugs and/or compounds by Sigma-Aldrich , Tocris Bioscience , and/or
Enzo Life Sciences )About This Section
Search Tocris compounds for FAM190B
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