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FAM58A Gene

protein-coding   GIFtS: 41

GC0XM141511
family with sequence similarity 58, member A
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
family with sequence similarity 58, member A1 2     OTTHUMP000000259362
MGC297291 2     OTTHUMP000000259322
STAR2 5     cyclin-M2
OTTHUMP000000259372     cyclin-related protein FAM58A2
cyclin M2     Cyclin-M3

External Ids:    HGNC: 284341   Entrez Gene: 920022   Ensembl: ENSG000001473827   UniProtKB: Q8N1B33   

Export aliases for FAM58A gene to outside databases

Previous GC identifers: GC0XM152375 GC0XM152506 GC0XM152854


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FAM58A:
Mutations in this gene have been shown to cause an X-linked dominant STAR syndrome that typically manifests syndactyly,
telecanthus and anogenital and renal malformations. The protein encoded by this gene contains a cyclin-box-fold domain
which suggests it may have a role in controlling nuclear cell division cycles. Alternative splicing results in
multiple transcript variants encoding distinct isoforms. (provided by RefSeq)

UniProtKB/Swiss-Prot: FA58A_HUMAN, Q8N1B3
Function: May have a role in cell proliferation


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FAM58A gene promoter:
         RFX1   ZID   CUTL1   RP58   FOXF2   HNF-1A   ISGF-3   FOXO4   FOXO1a   GR-alpha   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for FAM58A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for FAM58A 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq28   Ensembl cytogenetic band:  Xq28   HGNC cytogenetic band: Xq28

FAM58A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM58A gene location

GeneLoc gene densities for chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM141511:  view genomic region     (about GC identifiers)

Start:
141,511,974 bp from pter
End:
141,519,982 bp from pter
Size:
8,009 bases
Orientation:
minus strand

1 alternative location:
ChrX- 152,853,377-152,864,707     
RefSeq DNA sequence:
NC_000023.10  NT_167198.1  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: FA58A_HUMAN, Q8N1B3 (See protein sequence)
Recommended Name: Cyclin-related protein FAM58A  
Size: 248 amino acids; 28369 Da
Subunit: Interacts with SALL1
Sequence caution: Sequence=AAH01909.4; Type=Erroneous initiation; Sequence=AAH07232.4; Type=Erroneous initiation;
Sequence=AAH32121.1; Type=Erroneous initiation; Sequence=AAH71851.1; Type=Erroneous initiation;
Secondary accessions: Q2I380 Q330J9 Q96IU5 Q9BUU1
Alternative splicing: 2 isoforms:  Q8N1B3-1   Q8N1B3-2   

Explore the universe of human proteins at neXtProt for FAM58A: NX_Q8N1B3 

REFSEQ proteins (2 alternative transcripts): 
NP_001124469.1  NP_689487.2  


ENSEMBL proteins: 
ENSP00000359192 ENSP00000359194 ENSP00000359190 ENSP00000412865 ENSP00000384396 ENSP00000391173 
ENSP00000377422 ENSP00000276345 ENSP00000402949 


Human Recombinant Proteins 
Browse Purified and Recombinant Proteins at Millipore
Browse Human Recombinant Proteins at Sigma-Aldrich
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
OriGene Protein Over-expression Lysate: FAM58A
GenScript Custom Purified and Recombinant Proteins Services for FAM58A 
Novus Biologicals Lysate for FAM58A
Browse Sino Biological Recombinant Proteins
Browse ProSpec Recombinant Proteins


Antibodies for FAM58A: 
Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse Antibodies at Sigma-Aldrich
Browse R&D Systems for Antibodies
Browse OriGene Antibodies
GenScript Custom Superior Antibodies Services for FAM58A 
Browse antibodies at Epitomics

Assays for FAM58A: 
Browse Kits and Assays available from Millipore
Browse ELISAs at Sigma-Aldrich
OriGene Custom Immunoassay Development 
Browse OriGene Fluorogenic Cell Assay Kits 
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for FAM58A 
Browse Enzo Life Sciences for kits & assays
Uscn ELISAs and CLIAs for FAM58A 


(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

FAM58A for domains           About GeneDecksing

5 InterPro domains/families:
 IPR006670 Cyclin
 IPR011028 Cyclin-like
 IPR013763 Cyclin-related
 IPR006671 Cyclin_N
 IPR015429 Tscrpt_reg_cyclin

Graphical View of Domain Structure for InterPro Entry Q8N1B3

ProtoNet protein and cluster: Q8N1B3

UniProtKB/Swiss-Prot: FA58A_HUMAN, Q8N1B3
Similarity: Belongs to the cyclin family. Cyclin-like FAM58 subfamily


(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: FA58A_HUMAN, Q8N1B3
Function: May have a role in cell proliferation

Inhib.
RNA:
    
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich siRNA Panels and esiRNA and siRNA for FAM58A
Sigma-Aldrich shRNA for FAM58A
OriGene 29mer shRNA kits in GFP-retroviral vector (see all 3): FAM58A
OriGene shRNA RFP (see all 3): FAM58A
OriGene basic RS shRNA (see all 3): FAM58A
OriGene siRNA (see all 2): FAM58A
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of FAM58A 
miRNA:Sigma-Aldrich microRNA Mimics for FAM58A
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of FAM58A 
1 SABiosciences Assays for microRNA that regulate FAM58A:
hsa-miR-766

Gene
Editing:
Browse CompoZr Knockout ZFN at Sigma-Aldrich 

Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
Browse iPSC Reprogramming Factors at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: FAM58A
OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): FAM58A
OriGene untagged cDNA clones in CMV expression vector (see all 2): FAM58A
OriGene 3'-UTR clone (see all 2): FAM58A 
Browse MicroRNA Expression Plasmids 
GenScript Custom cDNA clone Services for FAM58A 
Browse Sino Biological Human cDNA Clones

Cell
Lines:
  
GenScript Custom overexpressing Cell Line Services for FAM58A 

1 Gene Ontology (GO) molecular function term (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005515 protein binding IPI18297069
About this table

FAM58A for ontologies           About GeneDecksing


(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section

    SABiosciences Custom Pathway-Focused PCR Arrays for FAM58A 

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM58A

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section
Browse Small Molecules at Sigma-Aldrich
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for FAM58A


(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib.
RNA:
     
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich siRNA Panels and esiRNA and siRNA for FAM58A
Sigma-Aldrich shRNA for FAM58A
OriGene 29mer shRNA kits in GFP-retroviral vector (see all 3): FAM58A
OriGene shRNA RFP (see all 3): FAM58A
OriGene basic RS shRNA (see all 3): FAM58A
OriGene siRNA (see all 2): FAM58A
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of FAM58A 
miRNA: Sigma-Aldrich microRNA Mimics for FAM58A
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of FAM58A 
1 SABiosciences Assays for microRNA that regulate FAM58A:
hsa-miR-766
Clones: Browse FLAG tag genes at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: FAM58A
OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): FAM58A
OriGene untagged cDNA clones in CMV expression vector (see all 2): FAM58A
OriGene 3'-UTR Clone (see all 2): FAM58A 
Browse OriGene MicroRNA Expression Plasmids 
GenScript Custom cDNA clone Services for FAM58A 
Primers: OriGene genome-wide validated SYBR primer pairs: FAM58A
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for FAM58A: PPH07947A

REFSEQ mRNAs for FAM58A gene (2 alternative transcripts): 

NM_001130997.1  NM_152274.3  

Additional cDNA sequence: 

AY445048.1 BC001909.1 BC007232.1 BC032121.2 BC071851.1 CR591949.1 CR604685.1 CR609517.1 
CR623450.1 DQ323993.1 

9 DOTS entries:

DT.403010  DT.100754240  DT.97844703  DT.121316730  DT.121316755  DT.95285215  DT.75102854  DT.91764825 
DT.95285212 

24/149 AceView cDNA sequences (see all 149):

CF529592 BQ669511 BU634035 CA307663 CB529466 AI368788 CD674841 CR604685 
AI559684 AW079353 AW675396 AI564254 BU685137 AW009759 BE646636 BQ670735 
BC071851 AW613907 BQ052733 BU628409 CR591949 CF529839 BM708687 BM785505 

highest scoring ESTs for FAM58A:

AW630663 BC001909 BC007232 BC032121 BC071851 BF568109 BG337452 BG680566 BG820886 BG820887 

Unigene Cluster for FAM58A:

Family with sequence similarity 58, member A
Hs.496943  [show with all ESTs]
Unigene Representative Sequence: BM473242


GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for FAM58A

ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c · 6d · 6e
SP1:                                                  -                           
SP2:                                                  -                           
SP3:                                                                              
SP4:        -     -     -                                                         
SP5:                                      -           -                           

About this scheme

ECgene alternative splicing isoforms for FAM58A
12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000465867 ENST00000370173 ENST00000370175(uc011myr.1 uc011mys.1 uc010nug.2)
ENST00000370171 ENST00000429336 ENST00000406277 ENST00000428722 ENST00000470284
ENST00000393837 ENST00000482182 ENST00000276345 ENST00000440428

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

FAM58A expression in normal and diseased human tissues

1  / 2  / 3

4 probe-sets matching FAM58A gene

Affymetrix
probe-set
Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
90281_f_at2, 3 U95-E 3 1.00 0.94 0.95 0.94 AI148734 0.60 1.00 0.82 1
89612_at2, 3 U95-E 3 1.00 0.83 0.62 1.06 AI971714 0.60 1.00 0.82 1
226466_s_at2, 3 U133-B 4 1.00 0.83 -- -- AL544688 0.40 1.00 0.76 1
226466_s_at2 U133Plus2 4 1.00 0.83 -- -- -- -- -- -- --
About this table

FAM58A for expression           About GeneDecksing

Data from Genenote  (Publications) and GNF BioGPS
    About these images
FAM58A gene expression
FAM58A gene electronic northern expression
FAM58A gene sage expression
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.496943
Primers: OriGene genome-wide validated SYBR primer pairs: FAM58A
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for FAM58A: PPH07947A
    SABiosciences Custom PCR Arrays for FAM58A 


(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for FAM58A gene from 5/11 species (see all 11)
Organism Gene Locus Description Human
Similarity
NCBI accessions
dog
(Canis familiaris)
LOC4922391   -- similar to CG31232-PA, isoform A 90.52(n)
90.05(a)
492239  XM_549359.2  XP_549359.2 
chimpanzee
(Pan troglodytes)
LOC7384831   -- similar to Family with sequence similarity 58, member more 99.66(n)
100(a)
738483  XM_001137453.1  XP_001137453.1 
cow
(Bos taurus)
LOC5347961   -- similar to RIKEN cDNA 1810009O10 gene 87.38(n)
89.25(a)
534796  XM_872954.2  XP_878047.1 
rat
(Rattus norvegicus)
Fam58b1   -- family with sequence similarity 58, member B 85.98(n)
92.06(a)
303321  NM_001025412.1  NP_001020583.1 
mouse
(Mus musculus)
1810009O10Rik1   -- RIKEN cDNA 1810009O10 gene 87.23(n)
92.52(a)
69109  NM_197989.1  NP_932106.1 
About this table        Species with no ortholog for FAM58A

ENSEMBL Gene Tree for FAM58A (if available)

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
Paralogs for FAM58A gene
CCNL22  CCNT22  CCNK2  CCNC2  CCNL12  CCNT12  

FAM58A for paralogs           About GeneDecksing



(SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

10/78 NCBI SNPs in FAM58A are shown (see all 78)
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidChr X posSequenceRecsAA
Chg
TypeMoreRecsAllele
freq
PopTotal
sample
More
----------
rs10489161,2
C,H,152865115(+) AAGACG/AGCGGC 2 -- ng511Minor allele frequency- A:0.00MN 184
rs22809241,2
C,F,152857693(+) AAAGCG/AGTTCT 2 -- int13Minor allele frequency- A:0.06EA NS 298
rs22809251,2
C,F,152857820(+) CCATCG/ACAACA 2 -- int14Minor allele frequency- A:0.06NS EA 418
rs22941031,2
C,A152859642(+) GGGGAT/CGGGGA 2 -- int15Minor allele frequency- C:0.00NS NA 126
rs22941041,2
C,F,152861390(+) GGCAGG/AGCCCC 2 -- int13Minor allele frequency- A:0.03EA NS 298
rs22941051,2
C,F,H152861426(+) CCCACC/TGGGTG 2 -- int13Minor allele frequency- T:0.02EA NS 298
rs38177181,2
C,F,A152860457(+) GAGCAT/CGCCAA 2 -- int14Minor allele frequency- C:0.13NS EA 418
rs44665871,2
C,F,A,152865666(+) ACCAGG/CCTCCC 2 -- ng518Minor allele frequency- C:0.08NS EA NA WA 418
rs44771971,2
C,F,A,H,152865451(+) CCAAGC/TTAGTG 2 -- ng5114Minor allele frequency- T:0.09NS EA NA WA 792
rs46251991,2
C,A,152865955(+) TTCTCT/GTCTGT 2 -- ng514Minor allele frequency- G:0.00NA WA 6
About this table

HapMap Linkage Disequilibrium images for FAM58A (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for FAM58A: --

QIAGEN SeqTarget long-range PCR primers for resequencing FAM58A 

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section

FAM58A for disorders           About GeneDecksing

OMIM: 300708   disorders: 300707  

UniProtKB/Swiss-Prot: FA58A_HUMAN, Q8N1B3

  • Defects in FAM58A are the cause of toe syndactyly, telecanthus, and anogenital and renal malformations (STAR)
  • [MIM:300707]; also known as STAR syndrome or syndactyly with renal and anogenital malformations

    Human Gene Mutation Database (HGMD): FAM58A

    Export disorders and mutations for FAM58A gene to outside databases


    (Possibly Related Articles in Doctor's Guide)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    8 PubMed articles for FAM58A gene integrated from 7 sources:
    (articles sorted by number of sources associating them with FAM58A)
    1. Mutations in the cyclin family member FAM58A cause an X-linked dominant disorder characterized by syndactyly, telecanthus and anogenital and renal malformations. (PubMed id 18297069)1, 2, 3 Unger S....Kohlhase J. (2008)
    2. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (2009)
    3. Identification of genes related to Parkinson's disease using expressed sequence tags. (PubMed id 17213182)1 Kim J.M....Kim N.S. (2006)
    4. The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (2006)
    5. From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)1 Wiemann S....Poustka A. (2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    8. DNA cloning using in vitro site-specific recombination. (PubMed id 11076863)1 Hartley J.L....Brasch M.A. (2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 92002 HGNC: 28434 AceView: MGC29729 Ensembl:ENSG00000147382 euGenes: HUgn92002
    ECgene: FAM58A H-InvDB: FAM58A

    (According to HUGE)
    About This Section
      --

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
      --

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
    About This Section
    Patent Information for FAM58A gene:
    Search GeneIP for patents involving FAM58A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
    Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
    About This Section

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services

     Predesigned and custom siRNAs for FAM58A Browse antibodies at Sigma-Aldrich
     Super-pooled esiRNAs for FAM58A Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for FAM58A microRNA Mimics for FAM58A
     "Your Favorite Gene" Pathways and Molecular Interaction Networks Browse Nano Scale siRNA at Sigma-Aldrich
     Browse iPSC Reprogramming Factors at Sigma-Aldrich Browse small molecules at Sigma-Aldrich
     Browse FLAG tag genes at Sigma-Aldrich Browse ELISAs at Sigma-Aldrich
     Browse microRNA Target Validation Systems at Sigma-Aldrich Browse CompoZr Knockout ZFN at Sigma-Aldrich
    feedback
      
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     Phosphatase Activity Assays/Reagents   Recombinant/Natural Proteins  
     Tagged/untagged cDNA clones
     Validated SYBR primer pairs
     Purified proteins from HEK293T cells
     Lysates
     Western blot validated antibodies
     shRNA in GFP-retroviral vector
     siRNA
     Custom Immunoassay Development
     Fluorogenic Cell Assay Kits
     miRNA Primers for qPCR Assays
     3' UTR Clones for miRNA Target Studies
     miRNA Expression Plasmids

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of FAM58A
     SeqTarget long-range PCR primers for resequencing FAM58A
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for FAM58A
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of FAM58A
     GenScript Custom Purified and Recombinant Proteins Services for FAM58A GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for FAM58A
     GenScript Custom Assay Services for FAM58A GenScript Custom Superior Antibodies Services for FAM58A
     GenScript Custom overexpressing Cell Line Services for FAM58A CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in FAM58A promoter
     Search Chromatin IP Primers for FAM58A
     RT2 qPCR Primer Assay for FAM58A
     Search GNC Networks for FAM58A
     Assays for microRNAs that regulate FAM58A
     SABiosciences Custom PCR Arrays for FAM58A
     Search Tocris compounds for FAM58A
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     Lysates for FAM58A
     Browse antibodies at Epitomics
     Browse ProSpec Recombinant Proteins

     ELISAs and CLIAs for FAM58A
           

    GeneCards Homepage - Last full update: 31 Dec 2010 - Incremental updates: 9 Jan 2011 , 10 Jan 2011

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