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FAM75D3 Gene

protein-coding   GIFtS: 26

GC09P084561
family with sequence similarity 75, member D3
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
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Aliases &
Descriptions
for FAM75D3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases & Descriptions
family with sequence similarity 75, member D31 2
FLJ440821 2
hypothetical protein LOC3897622
Putative FAM75-like protein FLJ440822
FAM75-like protein FLJ440822

External Ids:    HGNC: 386031   Entrez Gene: 3897622   Ensembl: ENSG000001867887   

Export aliases for FAM75D3 gene to outside databases


Summaries
for FAM75D3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
  --

Genomic Views
for FAM75D3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for FAM75D3
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for FAM75D3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q21.32   Ensembl cytogenetic band:  9q21.32   HGNC cytogenetic band: 9q21.32

FAM75D3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM75D3 gene location

GeneLoc gene densities for chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P084561:  view genomic region     (about GC identifiers)

Start:
 84,558,415 bp from pter
End:
 84,565,009 bp from pter
Size:
 6,595 bases
Orientation:
 plus strand

0 alternative location:
RefSeq DNA sequence:
NC_000009.11  NT_008470.19  

Proteins
for FAM75D3 gene

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section
REFSEQ proteins: NP_997299.2  
Human Recombinant Proteins 
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2 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0016020 membrane IEA--
GO:0016021 integral to membrane IEA--
About this table

FAM75D3 for ontologies           About GeneDecksing



Antibodies for FAM75D3: 
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Protein Domains/
Families
for FAM75D3 gene

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
   --

Gene Function
for FAM75D3 gene

(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section
Inhib.
RNA:    		Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich siRNA for FAM75D3
Sigma-Aldrich shRNA for FAM75D3
OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): FAM75D3
OriGene shRNA RFP (see all 2): FAM75D3
OriGene basic RS shRNA (see all 2): FAM75D3
OriGene siRNA (see all 2): FAM75D3
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of FAM75D3 
miRNA:Browse microRNA Mimics at Sigma-Aldrich
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of FAM75D3 
Search SABiosciences for Assays for microRNAs that regulate FAM75D3

Gene
Editing:		Browse CompoZr Knockout ZFN at Sigma-Aldrich 

Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
Browse iPSC Reprogramming Factors at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: FAM75D3
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: FAM75D3
Browse 3'-UTR reporter clones for miRNA target validation 
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Cell
Lines:  		GenScript Custom overexpressing Cell Line Services for FAM75D3 


Pathways & Interactions
for FAM75D3 gene

(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section

    SABiosciences Custom Pathway-Focused PCR Arrays for FAM75D3 

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM75D3

Drugs & Compounds
for FAM75D3 gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section
Browse Small Molecules at Sigma-Aldrich
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for FAM75D3


Transcripts
for FAM75D3 gene

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section
Inhib.
RNA:     		Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich siRNA for FAM75D3
Sigma-Aldrich shRNA for FAM75D3
OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): FAM75D3
OriGene shRNA RFP (see all 2): FAM75D3
OriGene basic RS shRNA (see all 2): FAM75D3
OriGene siRNA (see all 2): FAM75D3
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of FAM75D3 
miRNA: Browse microRNA Mimics at Sigma-Aldrich
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of FAM75D3 
Search SABiosciences for Assays for microRNAs that regulate FAM75D3
Clones: Browse FLAG tag genes at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: FAM75D3
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: FAM75D3
Browse 3'-UTR reporter clones for miRNA target validation 
Browse OriGene MicroRNA Expression Plasmids 
GenScript Custom cDNA clone Services for FAM75D3 
Primers: OriGene genome-wide validated SYBR primer pairs: FAM75D3
Browse OriGene validated miRNA SYBR primer pairs 
Search SABiosciences RT2 qPCR Primer Assays for FAM75D3

REFSEQ mRNAs for FAM75D3 gene: 

NM_207416.2  

Additional cDNA sequence: AK126070.1 

1 DOTS entry:

DT.97813988 

2 AceView cDNA sequences:

AK126070 NM_207416 

Unigene Cluster for FAM75D3:

Family with sequence similarity 75, member D3
Hs.522246  [show with all ESTs]
Unigene Representative Sequence: NM_207416


GeneLoc Exon Structure

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000334208(uc010mpt.2) ENST00000445385

Expression
for FAM75D3 gene

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

FAM75D3 expression in normal and diseased human tissues

Data from GNF BioGPS
    About these images

FAM75D3 gene expression
FAM75D3 gene electronic northern expression
FAM75D3 gene sage expression
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.522246
Primers: OriGene genome-wide validated SYBR primer pairs: FAM75D3
Browse OriGene validated miRNA SYBR primer pairs 
Search SABiosciences RT2 qPCR Primer Assays for FAM75D3
    SABiosciences Custom PCR Arrays for FAM75D3 


Orthologs
for FAM75D3 gene

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section
Orthologs for FAM75D3 gene from 1 species
Organism Gene Locus Description Human
Similarity		 NCBI accessions
mouse
(Mus musculus)		 1700013B16Rik5 13 (31.87 cM) RIKEN cDNA 1700013B16 gene   -- CR520895 
About this table        Species with no ortholog for FAM75D3

ENSEMBL Gene Tree for FAM75D3 (if available)

Paralogs
for FAM75D3 gene

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
  --

Genomic Variants
for FAM75D3 gene

(SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

10/17 NCBI SNPs in FAM75D3 are shown (see all 17)
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidChr 9 posSequenceRecsAA
Chg		TypeMoreRecsAllele
freq		PopTotal
sample		More
----------
rs6414861,2
C,A,84564152(+) CAGGGT/CTGGGG 1 -- ut315Minor allele frequency- C:0.17NA 12
rs27824051,2
C84564110(+) GCCCTC/TTAAGA 1 -- ut31 ese30--------
rs96449891,2
--84564118(+) AGACCC/TAATGG 1 -- ut31 ese30--------
rs117951901,2
C,H84564258(+) TCCTCC/TTGAAA 1 -- ut31 ese35Minor allele frequency- T:0.00NS EA NA 424
rs344754321,2
--84564036(+) GGAGCA/CCAGGG 1 -- ut310--------
rs351498521,2
--84565505(+) ACACG-/AAAAGG 1 -- ng310--------
rs585219911,2
C84564646(+) TCTTGC/TAGCCA 1 -- ut310--------
rs597703541,2
C,84565156(+) TTGTGG/CAAGAA 1 -- ng311Minor allele frequency- C:0.50WA 2
rs734782661,2
C,84564739(+) CATTTC/AAGGGG 1 -- ut311Minor allele frequency- A:0.50WA 2
rs749463621,2
F84560180(+) TTCCCC/ACCGCC 1 -- int11Minor allele frequency- A:0.50NA 4
About this table

HapMap Linkage Disequilibrium images for FAM75D3 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for FAM75D3: --

Search QIAGEN SeqTarget long-range PCR primers for resequencing for FAM75D3 

Disorders & Mutations
for FAM75D3 gene

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section
   --

Medical News
for FAM75D3 gene

(Possibly Related Articles in Doctor's Guide)
About This Section
   --

Publications
for FAM75D3 gene

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
About This Section

2 PubMed articles for FAM75D3 gene integrated from 7 sources:
(articles sorted by number of sources associating them with FAM75D3)
  1. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1 Humphray S.J.... Dunham I. (2004)
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)

External Searches for FAM75D3 gene

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  
  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

Genome Databases showing FAM75D3 gene

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 389762 HGNC: 38603 AceView: FLJ44082 Ensembl:ENSG00000186788 euGenes: HUgn389762
ECgene: FAM75D3 H-InvDB: FAM75D3

Other Databases showing FAM75D3 gene

(According to HUGE)
About This Section
   --

Specialized Databases showing FAM75D3 gene

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
   --

Intellectual Property
for FAM75D3 gene

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from XenneX, Inc.)
About This Section
Patent Information for FAM75D3 gene:
Search GeneIP for patents involving FAM75D3

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



Products
for FAM75D3 gene

(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
About This Section

 Millipore Custom Antibody & Bulk Services
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 Browse FLAG tag genes at Sigma-Aldrich Browse ELISAs at Sigma-Aldrich
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 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays
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