Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


Category   Symbol Source: HGNC EntrezGene Ensembl
GIFtS

Search by expression pattern Search by expression pattern



FASTKD2 Gene

protein-coding   GIFtS: 51

GC02P199479
FAST kinase domains 2
(Previous name: KIAA0971 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: KIAA0971)
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
FAST kinase domains 21 2
KIAA09711 2 3 5
FAST kinase domain-containing protein 22

External Ids:    HGNC: 291601   Entrez Gene: 228682   Ensembl: ENSG000001182467   UniProtKB: Q9NYY83   

Export aliases for FASTKD2 gene to outside databases

Previous GC identifers: GC02P207338 GC02P207630


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FASTKD2:
This gene encodes a protein that is localized in the mitochondrial inner compartment and that may play a role in
mitochondrial apoptosis. Nonsense mutations have been reported to result in cytochrome c oxidase deficiency. (provided
by RefSeq)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FASTKD2 gene promoter:
         Meis-1   HOXA9B   RFX1   POU3F2   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   MIF-1   MEF-2A   FOXI1   XBP-1   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for FASTKD2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q33.3   Ensembl cytogenetic band:  2q33.3   HGNC cytogenetic band: 2q33.3

FASTKD2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FASTKD2 gene location

GeneLoc gene densities for chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P199479:  view genomic region     (about GC identifiers)

Start:
199,479,654 bp from pter
End:
199,510,786 bp from pter
Size:
31,133 bases
Orientation:
plus strand

1 alternative location:
Chr2+ 207,630,081-207,657,233     
RefSeq DNA sequence:
NC_000002.11  NT_005403.17  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: FAKD2_HUMAN, Q9NYY8 (See protein sequence)
Recommended Name: FAST kinase domain-containing protein 2  
Size: 710 amino acids; 81463 Da
Caution: It is uncertain whether Met-1 or Met-17 is the initiator
Sequence caution: Sequence=BAA76815.2; Type=Erroneous initiation; Sequence=BAA91617.1; Type=Erroneous initiation;
Secondary accessions: Q9NVX6 Q9Y2H7
Alternative splicing: 2 isoforms:  Q9NYY8-1   Q9NYY8-2   

Explore the universe of human proteins at neXtProt for FASTKD2: NX_Q9NYY8 

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins (3 alternative transcripts): 
    NP_001129665.1  NP_001129666.1  NP_055744.2  


    ENSEMBL proteins: 
    ENSP00000384929 ENSP00000385990 ENSP00000409927 ENSP00000236980 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: FASTKD2
    GenScript Custom Purified and Recombinant Proteins Services for FASTKD2 
    Novus Biologicals Protein for FASTKD2
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins

    1 Gene Ontology (GO) cellular component term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739 mitochondrion IDA--
    About this table

    FASTKD2 for ontologies           About GeneDecksing



    Antibodies for FASTKD2: 
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for FASTKD2
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    GenScript Custom Superior Antibodies Services for FASTKD2 
    Novus Biologicals Antibody for FASTKD2
    Browse antibodies at Epitomics

    Assays for FASTKD2: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for FASTKD2 
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for FASTKD2 


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    FASTKD2 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR010622 FAST_Leu-rich
     IPR013584 RAP
     IPR013579 FAST_2

    Graphical View of Domain Structure for InterPro Entry Q9NYY8

    ProtoNet protein and cluster: Q9NYY8

    2 Blocks protein families:
    IPB013579 FAST kinase-like protein
    IPB013584 RAP domain


    UniProtKB/Swiss-Prot: FAKD2_HUMAN, Q9NYY8
    Similarity: Belongs to the FAST kinase family
    Similarity: Contains 1 RAP domain


    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    Inhib.
    RNA:
        
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for FASTKD2
    Sigma-Aldrich shRNA for FASTKD2
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 4): FASTKD2
    OriGene shRNA RFP (see all 4): FASTKD2
    OriGene basic RS shRNA (see all 4): FASTKD2
    OriGene siRNA (see all 3): FASTKD2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of FASTKD2 
    miRNA:Sigma-Aldrich microRNA Mimics for FASTKD2
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of FASTKD2 
    1 SABiosciences Assays for microRNA that regulate FASTKD2:
    hsa-miR-549

    Gene
    Editing:
    Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): FASTKD2
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): FASTKD2
    OriGene untagged cDNA clones in CMV expression vector (see all 2): FASTKD2
    OriGene 3'-UTR clone (see all 3): FASTKD2 
    Browse MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for FASTKD2 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:
      
    GenScript Custom overexpressing Cell Line Services for FASTKD2 

    2 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004672 protein kinase activity IEA--
    GO:0005524 ATP binding IEA--
    About this table

    FASTKD2 for ontologies           About GeneDecksing


    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section

        SABiosciences Custom Pathway-Focused PCR Arrays for FASTKD2 

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FASTKD2

    5/234 Interacting proteins for FASTKD2 (Q9NYY82) via UniProtKB, MINT, and/or STRING (see all 234)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AARS2Q5JTZ92MINT-8079030
    AASSQ9UDR52MINT-8079030
    ACAD9Q9H8452MINT-8079030
    ACADVLP497482MINT-8079030
    ACOT9Q9Y3052MINT-8079030
    About this table

    2 Gene Ontology (GO) biological process terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915 apoptosis IEA--
    GO:0045333 cellular respiration ISS--
    About this table

    FASTKD2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section
    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FASTKD2


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section

    Inhib.
    RNA:
         
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for FASTKD2
    Sigma-Aldrich shRNA for FASTKD2
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 4): FASTKD2
    OriGene shRNA RFP (see all 4): FASTKD2
    OriGene basic RS shRNA (see all 4): FASTKD2
    OriGene siRNA (see all 3): FASTKD2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of FASTKD2 
    miRNA: Sigma-Aldrich microRNA Mimics for FASTKD2
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of FASTKD2 
    1 SABiosciences Assays for microRNA that regulate FASTKD2:
    hsa-miR-549
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): FASTKD2
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): FASTKD2
    OriGene untagged cDNA clones in CMV expression vector (see all 2): FASTKD2
    OriGene 3'-UTR Clone (see all 3): FASTKD2 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for FASTKD2 
    Primers: OriGene genome-wide validated SYBR primer pairs: FASTKD2
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for FASTKD2: PPH10304A

    REFSEQ mRNAs for FASTKD2 gene (3 alternative transcripts): 

    NM_001136193.1  NM_001136194.1  NM_014929.3  

    Additional cDNA sequence: AK127714.1 

    14 DOTS entries:

    DT.95272454  DT.313604  DT.409179  DT.97770921  DT.120991695  DT.75166799  DT.92437633  DT.101976445 
    DT.91678029  DT.100036806  DT.100817752  DT.120991756  DT.40220861  DT.75185990 

    24/229 AceView cDNA sequences (see all 229):

    BQ720674 AK001315 AK129952 CA449424 BU625180 BQ002338 CD671615 CA313725 
    CF126553 BE463756 AL833877 AK021557 AI376597 NM_014929 CD671614 AI373235 
    BU753874 BM762657 BP344732 AU126490 AW151900 AI479715 BM852503 CA976132 

    highest scoring ESTs for FASTKD2:

    AI125268 AI760299 AA425100 AA425314 AA429164 AA526654 AA694345 AA729299 AA731700 AA835852 

    Unigene Clusters for FASTKD2:

    FAST kinase domains 2
    Hs.5930  [show with all ESTs], Hs.722628
    Unigene Representative Sequences: NM_001136194, AK127714


    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for FASTKD2 (see all 9)

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b
    SP1:                    -                 -                                               -                                   -           -               
    SP2:              -     -                 -                                               -                                   -           -               
    SP3:                                      -                                               -                                                               
    SP4:                                                                                      -                 -                 -                           
    SP5:                                                                                                                          -                           

    About this scheme

    ECgene alternative splicing isoforms for FASTKD2
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000471788 ENST00000403094 ENST00000402774 ENST00000487777(uc002vbw.1)
    ENST00000418289 ENST00000236980(uc002vbu.2 uc002vbv.2 uc002vbx.2)


    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    FASTKD2 expression in normal and diseased human tissues

    1  / 2  / 3

    10 probe-sets matching FASTKD2 gene

    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    62951_s_at2, 3 U95-C 1 1.00 1.00 0.91 1.27 AI760299 1.00 1.00 1.00 1
    53716_at2, 3 U95-C 1 1.00 1.00 0.86 1.06 AI125268 1.00 1.00 1.00 1
    54425_at2 U95-B 1 0.88 1.00 0.82 0.96 -- -- -- -- --
    39299_at2, 3 U95-A 1 0.50 1.00 0.45 0.72 AB023188 0.80 1.00 0.91 1
    216996_s_at2, 3 U133-A 1 1.00 1.00 -- -- AK021557 0.80 1.00 0.91 1
    229135_at2 U133-B 1 1.00 1.00 -- -- -- -- -- -- --
    205976_at2, 3 U133-A 1 0.36 1.00 -- -- NM_014929 0.60 1.00 0.82 1
    216996_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    229135_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    205976_at2 U133Plus2 1 0.36 1.00 -- -- -- -- -- -- --
    About this table

    FASTKD2 for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    FASTKD2 gene expression
    FASTKD2 gene electronic northern expression
    FASTKD2 gene sage expression
    About these images

    CGAP SAGE TAG: CATTTGTAAA

    SOURCE GeneReport for Unigene clusters: Hs.5930 Hs.722628
    Primers: OriGene genome-wide validated SYBR primer pairs: FASTKD2
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for FASTKD2: PPH10304A
        SABiosciences Custom PCR Arrays for FASTKD2 


    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section

    Orthologs for FASTKD2 gene from 5 species
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    FASTKD21   -- FAST kinase domains 2 79.8(n)
    69.4(a)
    478884  XM_536043.2  XP_536043.2 
    rat
    (Rattus norvegicus)
    Fastkd21   -- FAST kinase domains 2 77.28(n)
    65.32(a)
    301463  NM_001009673.1  NP_001009673.1 
    mouse
    (Mus musculus)
    Fastkd21 , 5 1 (32.31 cM)5
    FAST kinase domains 21, 5 77.89(n)1
    66.76(a)1
    756191  NM_172422.21  NP_766010.11 
     AI4653495  AK0131255  (see all 22)
    chicken
    (Gallus gallus)
    FASTKD21   -- FAST kinase domains 2 58.36(n)
    45.17(a)
    424096  XM_421951.2  XP_421951.1 
    zebrafish
    (Danio rerio)
    LOC5643821   -- similar to FAST kinase domains 2 51.87(n)
    37.76(a)
    564382  XM_687718.3  XP_692810.3 
    About this table        Species with no ortholog for FASTKD2

    ENSEMBL Gene Tree for FASTKD2 (if available)

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
      --

    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/255 NCBI SNPs in FASTKD2 are shown (see all 255)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 2 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ----------
    rs7259801,2
    C,F,O,A,207638580(+) AAGTTC/GAAGAT 3 -- int115Minor allele frequency- G:0.38NA EA NS WA 1079
    rs7685331,2
    C,F,A,207640837(-) TTACAC/TATTAT 3 -- int11Minor allele frequency- T:0.14NA 72
    rs8788321,2
    C,F,A,207650638(+) ACCAGT/CTATTC 3 -- int19Minor allele frequency- C:0.14NS EA NA WA 624
    rs8794721,2
    C,F,A,207651782(-) ACTATC/TCTTTG 3 -- int121Minor allele frequency- T:0.13EA NA MN NS WA 1570
    rs8886211,2
    C,F,O,A,207649350(-) ACACTA/CATGAC 3 -- int115Minor allele frequency- C:0.43EA NA NS WA 1042
    rs10018051,2
    C,F,O,207659531(+) TTCCAA/GTTTAT 2 -- ut3117Minor allele frequency- C:0.01NA EA NS WA 1128
    rs10487831,2
    C,F,A,207657153(+) TTCTCC/TTTCTT 2 -- ut31 trp313Minor allele frequency- T:0.41EA MN NS NA WA 3169
    rs19818001,2
    --207636408(-) aattcC/Tttgat 3 -- int10--------
    rs21120881,2
    C,F,A,H,207645042(-) acaaaT/Cgaaag 3 -- int18Minor allele frequency- C:0.35NA WA 244
    rs21120891,2
    --207635308(-) cccggC/Gtaatt 3 -- int10--------
    About this table

    HapMap Linkage Disequilibrium images for FASTKD2 (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for FASTKD2: --

    QIAGEN SeqTarget long-range PCR primers for resequencing FASTKD2 

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    FASTKD2 for disorders           About GeneDecksing

    OMIM: 612322   disorders: 220110  

    Human Gene Mutation Database (HGMD): FASTKD2
    Human Genome Epidemiology (HuGE) Navigator: FASTKD2 (1 document)

    Export disorders and mutations for FASTKD2 gene to outside databases


    (Possibly Related Articles in Doctor's Guide)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/11 PubMed articles for FASTKD2 gene, integrated from 7 sources (see all 11):
    (articles sorted by number of sources associating them with FASTKD2)
    1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (2000)
    5. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)1, 2 Nagase T.... Ohara O. (1999)
    6. Genome-Wide Association Study of Anthropometric Trait s and Evidence of Interactions With Age and Study Year in Filipino Women. (PubMed id 20966902)1 Croteau-Chonka D.C....Mohlke K.L. (2010 Oct 21)
    7. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)
    8. FASTKD2 nonsense mutation in an infantile mitochondrial encephalomyopathy associated with cytochrome c oxidase deficiency. (PubMed id 18771761)1 Ghezzi D....Zeviani M. (2008)
    9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 22868 HGNC: 29160 AceView: KIAA0971 Ensembl:ENSG00000118246 euGenes: HUgn22868
    ECgene: FASTKD2 H-InvDB: FASTKD2

    (According to HUGE)
    About This Section
    HUGE: KIAA0971

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
      --

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
    About This Section
    Patent Information for FASTKD2 gene:
    Search GeneIP for patents involving FASTKD2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
    Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
    About This Section

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services

     Predesigned and custom siRNAs for FASTKD2 Antibodies for FASTKD2
     Super-pooled esiRNAs for FASTKD2 Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for FASTKD2 microRNA Mimics for FASTKD2
     "Your Favorite Gene" Pathways and Molecular Interaction Networks Browse Nano Scale siRNA at Sigma-Aldrich
     Browse iPSC Reprogramming Factors at Sigma-Aldrich Browse small molecules at Sigma-Aldrich
     Browse FLAG tag genes at Sigma-Aldrich Browse ELISAs at Sigma-Aldrich
     Browse microRNA Target Validation Systems at Sigma-Aldrich Browse CompoZr Knockout ZFN at Sigma-Aldrich
    feedback
      
     Antibodies   Cell Culture Products  
     ELISAs   Flow Cytometry Kits  
     Primer Pairs   Kinase Activity Assays/Reagents  
     ELISpot Kits/Development Modules   TFB/Immunoprecipitation Assays  
     Apoptosis Detection Kits/Reagents   Protease Activity Assays/Reagents  
     DNA Damage/Repair Kits/Reagents   Multiplex/Array Assay Kits/Reagents  
     Cell Selection/Detection Kits/Reagents   ELISA/Assay Development Kits/Reagents  
     Phosphatase Activity Assays/Reagents   Recombinant/Natural Proteins  
     Tagged/untagged cDNA clones
     Validated SYBR primer pairs
     Purified proteins from HEK293T cells
     Lysates
     Western blot validated antibodies
     shRNA in GFP-retroviral vector
     siRNA
     Custom Immunoassay Development
     Fluorogenic Cell Assay Kits
     miRNA Primers for qPCR Assays
     3' UTR Clones for miRNA Target Studies
     miRNA Expression Plasmids

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of FASTKD2
     SeqTarget long-range PCR primers for resequencing FASTKD2
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of FASTKD2
     GenScript Custom Purified and Recombinant Proteins Services for FASTKD2 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for FASTKD2
     GenScript Custom Assay Services for FASTKD2 GenScript Custom Superior Antibodies Services for FASTKD2
     GenScript Custom overexpressing Cell Line Services for FASTKD2 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in FASTKD2 promoter
     Search Chromatin IP Primers for FASTKD2
     RT2 qPCR Primer Assay for FASTKD2
     Search GNC Networks for FASTKD2
     Assays for microRNAs that regulate FASTKD2
     SABiosciences Custom PCR Arrays for FASTKD2
     Search Tocris compounds for FASTKD2
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     Antibodies for FASTKD2
     Proteins for FASTKD2
     Browse antibodies at Epitomics
     Browse ProSpec Recombinant Proteins

     ELISAs and CLIAs for FASTKD2
           

    GeneCards Homepage - Last full update: 31 Dec 2010 - Incremental updates: 9 Jan 2011 , 10 Jan 2011

    View Random Gene

    Category
    GIFtS Group
    The GeneCards human gene database gene index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    FASTKD2 gene at Home site.
    hostname: www-ab3 db genecards_305 index build: 81e solr: 1.4