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Aliases & Descriptionsfor FTSJ3 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section Aliases & Descriptions FtsJ homolog 3 (E. coli)1 2 FLJ200622 Protein ftsJ homolog 32 3 putative rRNA methyltransferase 32 rRNA (uridine-2'-O-)-methyltransferase 32 3 EC 2.1.1.-3 EPCS32
Export aliases for FTSJ3 gene to outside databases Previous GC identifers: GC17M061547 GC17M064323 GC17M062237 GC17M062370 GC17M059250 GC17M061896
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Summariesfor FTSJ3 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for FTSJ3 : Although the function of this gene is not known, the existence of this gene is supported by mRNA and EST data. A possible function of the encoded protein can be inferred from amino acid sequence similarity to the E.coli FtsJ protein and to a mouse protein possibly involved in embryogenesis. (provided by RefSeq) UniProtKB/Swiss-Prot: RRMJ3_HUMAN, Q8IY81 Function : Probable methyltransferase (By similarity)Gene Wiki entry for FTSJ3
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Genomic Viewsfor FTSJ3 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60) ,
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences )About This Section Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the FTSJ3 gene promoter: Egr-1 NF-kappaB1 p53 NF-kappaB IRF-1 GCNF-2 GCNF-1 PPAR-gamma2 PPAR-gamma1 Sox9 Other transcription factors Search SABiosciences Chromatin IP Primers for FTSJ3 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for FTSJ3
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 17q23.3 Ensembl cytogenetic band: 17q23.3 HGNC cytogenetic band: 17q23 FTSJ3 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 17 GeneLoc Exon Structure
GeneLoc location for GC17M057264: view genomic region
(about GC identifiers )
Start:
57,264,855 bp from pter
End:
57,273,093 bp from pter
Size:
8,239 bases
Orientation:
minus strand
1 alternative location : Chr 17- 61,896,795-61,905,031
RefSeq DNA sequence: NC_000017.10 NT_010783.15
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Proteinsfor FTSJ3 gene
(According to
1 UniProtKB ,
neXtProt ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological , and/or
ProSpec ,
Biochemical Assays by
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene ,
Antibodies by
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals , and/or
Epitomics )
About This Section UniProtKB/Swiss-Prot: RRMJ3_HUMAN, Q8IY81 (See
protein sequence )Recommended Name: Putative rRNA methyltransferase 3 Size : 847 amino acids; 96558 Da
Subcellular location : Nucleus, nucleolus
Sequence caution : Sequence=BAA90924.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions : B2RCA5 D3DU22 Q8N3A3 Q8WXX1 Q9BWM4 Q9NXT6Explore the universe of human proteins at neXtProt for FTSJ3: NX_Q8IY81 Post-translational modifications:
View phosphorylation sites using PhosphoSite 2
REFSEQ proteins: NP_060117.3 ENSEMBL proteins: ENSP00000337518 ENSP00000396673 Human Recombinant Proteins 2 Gene Ontology (GO) cellular component terms (GO ID links to tree view) :
About this table
FTSJ3 for ontologies About GeneDecksing Antibodies for FTSJ3: Assays for FTSJ3:
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Protein
Domains/ Familiesfor FTSJ3 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
FTSJ3 for domains About GeneDecksing 3 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry Q8IY81 ProtoNet protein and cluster: Q8IY81
2 Blocks protein families : IPB002877 Cell division protein FtsJ IPB012920 Spb1 UniProtKB/Swiss-Prot: RRMJ3_HUMAN, Q8IY81 Similarity : Belongs to the methyltransferase superfamily. RlmE family
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Gene Functionfor FTSJ3 gene
(According to UniProtKB ,
IUBMB ,and/or
Genatlas , Animal models from MGI Dec 24 2010,
shRNA from
OriGene ,
Sigma-Aldrich ,
RNAi from
Millipore ,
siRNAs from
Sigma-Aldrich ,
OriGene ,
Qiagen ,
Super-pooled esiRNAs from Sigma-Aldrich ,
microRNA from Sigma-Aldrich ,
Qiagen ,
SABiosciences ,
Clones from Millipore ,
Sigma-Aldrich ,
OriGene ,
GenScript ,
Sino Biological ,
Cell Lines from GenScript ,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene .)
About This Section UniProtKB/Swiss-Prot: RRMJ3_HUMAN, Q8IY81 Function : Probable methyltransferase (By similarity)Catalytic activity : S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methyluridineEnzyme Number (IUBMB): EC 2.1.1.-
3 Gene Ontology (GO) molecular function terms (GO ID links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0003676 nucleic acid binding
IEA -- GO:0008168 methyltransferase activity
IEA -- GO:0016740 transferase activity
IEA --
About this table
FTSJ3 for ontologies About GeneDecksing
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Pathways & Interactionsfor FTSJ3 gene
(Pathways according to
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
PCR Arrays from
SABiosciences ,
Proteins Network according to
SABiosciences ,
Sigma-Aldrich ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene) .
About This Section SABiosciences Custom Pathway-Focused PCR Arrays for FTSJ3 Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FTSJ3 1 Interacting protein for FTSJ3 (Q8IY81 2 ) via UniProtKB, MINT, and/or STRING About this table 3 Gene Ontology (GO) biological process terms (GO ID links to tree view) :
About this table
FTSJ3 for ontologies About GeneDecksing
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Drugs & Compoundsfor FTSJ3 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
About This Section Browse Tocris compounds for FTSJ3
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Transcriptsfor FTSJ3 gene (GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
Millipore ,
siRNAs from
Sigma-Aldrich ,
OriGene ,
Qiagen ,
Super-pooled esiRNAs from Sigma-Aldrich ,
shRNA from
Sigma-Aldrich ,
OriGene ,
microRNA from Sigma-Aldrich ,
Qiagen ,
SABiosciences ,
Tagged/untagged cDNA clones from
OriGene ,
Sigma-Aldrich ,
GenScript ,
Primers from
OriGene and/or
SABiosciences )About This Section REFSEQ mRNAs for FTSJ3 gene: NM_017647.3
Additional cDNA sequence: AF147378.1 AF327355.1 AK000069.1 AK095861.1 AK296715.1 AK307398.1 AK315010.1 AL834482.1 BC000131.1 BC036710.2 CR596573.1 CR614545.1
19 DOTS entries : DT.100745357 DT.100745437 DT.97855470 DT.86837221 DT.100724310 DT.91723560 DT.102838781 DT.95202158
DT.100745450 DT.121007096 DT.100745389 DT.92440817 DT.95070697 DT.101964800 DT.101977643 DT.121007354 DT.121007509 DT.95070700 DT.102838780 11 AceView cDNA sequences :
AK095861 BC000131 CR614545 AL834482 CR596573 AK000069 NM_017647 BC036710 AF327355 AF147378 AK027463
highest scoring ESTs for FTSJ3 :AK095861 AA159880 AA715365 AF142579 AK000069 AL526114 AL834482 BC000131 BC036710 BE622397 Unigene Cluster for FTSJ3:
FtsJ homolog 3 (E. coli) Hs.463785 [show with all ESTs ] Unigene Representative Sequence: NM_017647 GeneLoc Exon Structure 5/13 Alternative Splicing Database (ASD) splice patterns (SP) for FTSJ3 (see all 13 ) ExUns: 1 ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c · 6d ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · SP1 :       -   -       -         -   -                             SP2 :   -   -   -   -       -         -   -                             SP3 :               -         -   -                             SP4 :                                                     SP5 :       -   -       -                                      
ExUns: 17b · 17c ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23a · 23b ^ 24 SP1 :                     SP2 :                     SP3 :                     SP4 :                     SP5 :                    
About this scheme ECgene alternative splicing isoforms for FTSJ3 2 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000336599 (uc002jbz.2 ) ENST00000427159 (uc002jca.2 )
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Expression for FTSJ3 gene
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Primers from
OriGene and/or
SABiosciences
)
About This Section FTSJ3 expression in normal and diseased human tissues 1 / 2 / 3
3 probe-sets matching FTSJ3 gene
Affymetrix probe-set
Array
GeneAnnot data
GeneNote data
GeneTide data
# genes
Sensitivity
Specificity
Correlation
Length
Gb_Accession
Consensus
Uniqueness
Score
Rank
43464_at2 , 3
U95-B
1
1.00
1.00
1.00
1.00
T59668
0.40
1.00
0.76
1
218103_at2 , 3
U133-A
1
1.00
1.00
--
--
NM_017647
0.60
1.00
0.82
1
218103_at2
U133Plus2
1
1.00
1.00
--
--
--
--
--
--
--
About this table
FTSJ3 for expression About GeneDecksing Data from
Genenote  
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: ACCCTTTTTT SOURCE GeneReport for Unigene cluster: Hs.463785 SABiosciences Custom PCR Arrays for FTSJ3
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Orthologsfor FTSJ3 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
About This Section
Orthologs for FTSJ3 gene from 5/21 species (see all 21 )
About this table Species with no ortholog for FTSJ3 ENSEMBL Gene Tree for FTSJ3 (if available)
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Paralogsfor FTSJ3 gene (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section --
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Genomic Variantsfor FTSJ3 gene (SNPs according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Resequencing Primers from Qiagen )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Chr 17 pos Sequence Recs AA Chg Type More Recs Allele freq Pop Total sample More
About this table HapMap Linkage Disequilibrium images for FTSJ3 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for FTSJ3: --
QIAGEN SeqTarget long-range PCR primers for resequencing FTSJ3
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Disorders & Mutationsfor FTSJ3 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
LSDB, HGMD, GAD ,
HuGE Navigator ,
and/or TGDB .)
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Medical Newsfor FTSJ3 gene (Possibly Related Articles in
Doctor's Guide )
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Publicationsfor FTSJ3 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 UniProtKB/TrEMBL , and/or
7 Novoseek )
About This Section 10/20 PubMed articles for FTSJ3 gene, integrated from 7 sources (see all 20 ): (articles sorted by number of sources associating them with FTSJ3) Phosphoproteome analysis of the human mitotic spindle. (PubMed id 16565220) 1 , 2 Nousiainen M.... Koerner R. (2006) A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243) 1 , 2 Beausoleil S.A.... Gygi S.P. (2006) Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983) 1 , 2 Olsen J.V....Mann M. (2006) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 Gerhard D.S....Malek J. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) Functional proteomic analysis of human nucleolus. (PubMed id 12429849) 1 , 2 Scherl A.... Diaz J.-J. (2002) Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330) 2 Gauci S....Mohammed S. (2009) Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861) 2 Choudhary C.... Mann M. (2009) Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332) 2 Mayya V.... Han D.K. (2009) Evaluation of the low-specificity protease elastase for large-scale phosphoproteome analysis. (PubMed id 19007248) 2 Wang B.... Korner R. (2008)
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External Searches for FTSJ3 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing FTSJ3 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing FTSJ3 gene
(According to HUGE )
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Specialized Databases showing FTSJ3 gene (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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About This Section Patent Information for FTSJ3 gene: Search GeneIP for patents involving FTSJ3 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor FTSJ3 gene (Antibodies, recombinant proteins, and assays by Millipore , Sigma-Aldrich , R&D Systems , Qiagen , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Epitomics , ProSpec , Uscn , Clones available from Millipore , Sigma-Aldrich , OriGene , GenScript , Sino Biological , PCR Arrays from SABiosciences , Drugs and/or compounds by Sigma-Aldrich , Tocris Bioscience , and/or
Enzo Life Sciences )About This Section
Search Tocris compounds for FTSJ3
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