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FUK Gene

protein-coding   GIFtS: 53

GC16P056320
fucokinase
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
fucokinase1 2
Fucokinase3
FLJ394081 2
L-fucose kinase2
1110046B12Rik2
EC 2.7.1.523

External Ids:    HGNC: 295001   Entrez Gene: 1972582   Ensembl: ENSG000001573537   UniProtKB: Q8N0W33   

Export aliases for FUK gene to outside databases

Previous GC identifers: GC16P061190 GC16P070908 GC16P070223 GC16P070264 GC16P069045 GC16P070488


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FUK:
The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase
family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the
first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in
mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis.
While several transcript variants may exist for this gene, the full-length nature of only one has been described to
date. (provided by RefSeq)

UniProtKB/Swiss-Prot: FUK_HUMAN, Q8N0W3
Function: Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FUK gene promoter:
         GATA-3   GATA-2   GATA-1   c-Myb   oct-B3   POU2F1   POU2F2   POU2F2 (Oct-2.1)   POU2F2B   POU2F2C   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for FUK

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q22.1   Ensembl cytogenetic band:  16q22.1   HGNC cytogenetic band: 16q22.1

FUK Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FUK gene location

GeneLoc gene densities for chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P056320:  view genomic region     (about GC identifiers)

Start:
56,320,614 bp from pter
End:
56,346,293 bp from pter
Size:
25,680 bases
Orientation:
plus strand

1 alternative location:
Chr16+ 70,488,498-70,514,177     
RefSeq DNA sequence:
NC_000016.9  NT_010498.15  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: FUK_HUMAN, Q8N0W3 (See protein sequence)
Recommended Name: L-fucose kinase  
Size: 1084 amino acids; 117623 Da
Sequence caution: Sequence=BAB71190.1; Type=Frameshift; Positions=19; Sequence=CAD29647.1; Type=Frameshift;
Positions=19;
Secondary accessions: Q5PSM3 Q5XKL6 Q6ZRA0 Q96MT9
Alternative splicing: 2 isoforms:  Q8N0W3-1   Q8N0W3-2   

Explore the universe of human proteins at neXtProt for FUK: NX_Q8N0W3 

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_659496.2  

    ENSEMBL proteins: 
    ENSP00000288078 ENSP00000368192 ENSP00000408007 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    GenScript Custom Purified and Recombinant Proteins Services for FUK 
    Novus Biologicals Proteins for FUK
    Novus Biologicals Lysate for FUK
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins

    1 Gene Ontology (GO) cellular component term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737 cytoplasm IEA--
    About this table

    FUK for ontologies           About GeneDecksing



    Antibodies for FUK: 
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for FUK
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    GenScript Custom Superior Antibodies Services for FUK 
    Novus Biologicals Antibodies for FUK
    Browse antibodies at Epitomics

    Assays for FUK: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for FUK 
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for FUK 


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    FUK for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR006206 Mevalonate/galactokinase
     IPR020568 Ribosomal_S5_D2-typ_fold
     IPR012887 Fucokinase
     IPR006204 GHMP_kinase
     IPR014721 Ribosomal_S5_D2-typ_fold_subgr

    Graphical View of Domain Structure for InterPro Entry Q8N0W3

    ProtoNet protein and cluster: Q8N0W3

    3 Blocks protein families:
    IPB006203 GHMP kinase
    IPB012887 L-fucokinase
    IPB013750 GHMP kinase


    UniProtKB/Swiss-Prot: FUK_HUMAN, Q8N0W3
    Similarity: Belongs to the GHMP kinase family


    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    UniProtKB/Swiss-Prot: FUK_HUMAN, Q8N0W3
    Function: Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides
    Catalytic activity: ATP + L-fucose = ADP + beta-L-fucose 1-phosphate
    Enzyme Number (IUBMB): EC 2.7.1.52 

    Inhib.
    RNA:
        
    Browse for Gene Knock-down Tools from Millipore
    Sigma-Aldrich Nano Scale siRNA for FUK
    Sigma-Aldrich siRNA Panels and esiRNA and siRNA for FUK
    Sigma-Aldrich shRNA Panels and shRNA for FUK
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): FUK
    OriGene shRNA RFP (see all 2): FUK
    OriGene basic RS shRNA (see all 2): FUK
    OriGene siRNA (see all 2): FUK
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of FUK 
    miRNA:Sigma-Aldrich microRNA Mimics for FUK
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of FUK 
    1 SABiosciences Assays for microRNA that regulate FUK:
    hsa-miR-589

    Gene
    Editing:
    Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: FUK
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: FUK
    OriGene untagged cDNA clones in CMV expression vector (see all 2): FUK
    OriGene 3'-UTR clone: FUK 
    Browse MicroRNA Expression Plasmids 
    GenScript cDNA clone with any tag delivered in your preferred vector: FUK 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:
      
    GenScript Custom overexpressing Cell Line Services for FUK 

    5 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166 nucleotide binding IEA--
    GO:0005524 ATP binding IEA--
    GO:0016301 kinase activity ----
    GO:0016740 transferase activity IEA--
    GO:0050201 fucokinase activity NAS12056818
    About this table

    FUK for ontologies           About GeneDecksing


    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section


    FUK for pathways           About GeneDecksing

    1 Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Pathway for  FUK
        Fructose and Mannose Metabolism

    3 Kegg Pathways  (Kegg details for FUK):
        hsa00051 Fructose and mannose metabolism
    hsa00520 Amino sugar and nucleotide sugar metabolism
    hsa01100 Metabolic pathways

        SABiosciences Custom Pathway-Focused PCR Arrays for FUK 

        Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Molecular Interaction Network for FUK
        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FUK

    1 Interacting protein for FUK (ENSP000003681923) via UniProtKB, MINT, and/or STRING
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TNNI3KENSP000003599283STRING: ENSP00000359928
    About this table

    2 Gene Ontology (GO) biological process terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008152 metabolic process IEA--
    GO:0016310 phosphorylation ----
    About this table

    FUK for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section
    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FUK


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section

    Inhib.
    RNA:
         
    Browse for Gene Knock-down Tools from Millipore
    Sigma-Aldrich Nano Scale siRNA for FUK
    Sigma-Aldrich siRNA Panels and esiRNA and siRNA for FUK
    Sigma-Aldrich shRNA Panels and shRNA for FUK
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): FUK
    OriGene shRNA RFP (see all 2): FUK
    OriGene basic RS shRNA (see all 2): FUK
    OriGene siRNA (see all 2): FUK
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of FUK 
    miRNA: Sigma-Aldrich microRNA Mimics for FUK
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of FUK 
    1 SABiosciences Assays for microRNA that regulate FUK:
    hsa-miR-589
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: FUK
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: FUK
    OriGene untagged cDNA clones in CMV expression vector (see all 2): FUK
    OriGene 3'-UTR Clone: FUK 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript cDNA clone with any tag delivered in your preferred vector: FUK 
    Primers: OriGene genome-wide validated SYBR primer pairs: FUK
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for FUK: PPH07550A

    REFSEQ mRNAs for FUK gene: 

    NM_145059.2  

    Additional cDNA sequence: 

    AJ441184.1 AK056456.1 AK092025.1 AK096727.1 AK128387.1 AK293794.1 AK315590.1 BC013735.1 
    BC032542.1 CR610176.1 

    11 DOTS entries:

    DT.445211  DT.100751447  DT.40189818  DT.100672672  DT.99942941  DT.91681107  DT.91681983  DT.99959196 
    DT.102836007  DT.92036016  DT.120681529 

    24/91 AceView cDNA sequences (see all 91):

    AW075581 CD369374 AI191022 NM_145059 AI650939 BC032542 AI655796 AK074168 
    BX281225 AK096727 BM790446 AY358187 BI910114 AI243474 AA552095 AW674711 
    BM693199 BU631695 BM469047 BX398994 AK123470 AA628563 AA301456 T32783 

    highest scoring ESTs for FUK:

    AA310192 AA335251 AA535624 AA552095 AA566058 AA628563 AA872349 AA923501 AI038993 AI191022 

    Unigene Cluster for FUK:

    Fucokinase
    Hs.7907  [show with all ESTs]
    Unigene Representative Sequence: BC032542


    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for FUK (see all 10)

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15a · 15b ^ 16 ^ 17 ^ 18a · 18b ^
    SP1:        -                                         -           -           -                                               -                                 
    SP2:        -                 -                       -           -           -                                               -                                 
    SP3:        -                 -                       -                       -                 -                             -                       -         
    SP4:        -     -     -     -     -     -     -     -     -     -     -     -     -           -                 -                                             
    SP5:        -                 -                                                                                                                                 

    ExUns: 19 ^ 20a · 20b ^ 21a · 21b ^ 22a · 22b ^ 23 ^ 24a · 24b ^ 25
    SP1:              -           -     -                 -               
    SP2:                          -     -                 -               
    SP3:                          -     -                                 
    SP4:                          -     -                 -               
    SP5:                                                                  

    About this scheme

    ECgene alternative splicing isoforms for FUK
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000288078(uc002eyy.2 uc002eyz.2) ENST00000378912(uc010cft.2)
    ENST00000464499(uc010vmb.1) ENST00000498702 ENST00000485034 ENST00000428974


    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    FUK expression in normal and diseased human tissues

    1  / 2  / 3

    3 probe-sets matching FUK gene

    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    62565_at2, 3 U95-C 1 1.00 1.00 1.00 1.00 W21872 0.60 1.00 0.82 1
    226072_at2, 3 U133-B 1 1.00 1.00 -- -- AW080798 0.80 1.00 0.91 1
    226072_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    About this table

    FUK for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    FUK gene expression
    FUK gene electronic northern expression
    FUK gene sage expression
    About these images

    CGAP SAGE TAG: TGAGCGTGGG

    SOURCE GeneReport for Unigene cluster: Hs.7907
    Primers: OriGene genome-wide validated SYBR primer pairs: FUK
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for FUK: PPH07550A
        SABiosciences Custom PCR Arrays for FUK 


    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section

    Orthologs for FUK gene from 5/9 species (see all 9)
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    FUK1   -- fucokinase 88.26(n)
    89.9(a)
    489715  XM_546835.2  XP_546835.2 
    chimpanzee
    (Pan troglodytes)
    FUK1   -- fucokinase 99.08(n)
    99.17(a)
    468015  XM_001170471.1  XP_001170471.1 
    cow
    (Bos taurus)
    FUK1   -- fucokinase 86.47(n)
    87.49(a)
    519181  XM_597394.3  XP_597394.2 
    rat
    (Rattus norvegicus)
    Fuk1   -- fucokinase 84.51(n)
    85.56(a)
    307848  XM_226508.4  XP_226508.4 
    mouse
    (Mus musculus)
    Fuk1 , 5 8 (57.79 cM)5
    fucokinase1, 5 84.81(n)1
    85.83(a)1
    2347301  NM_172283.21  NP_758487.21 
     AI3032785  AI4132745  (see all 23)
    About this table        Species with no ortholog for FUK

    ENSEMBL Gene Tree for FUK (if available)

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
      --

    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/274 NCBI SNPs in FUK are shown (see all 274)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 16 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ----------
    rs7446721,2
    C,F,A70503967(+) ggtctG/Cgaact 1 -- int17Minor allele frequency- C:0.50NS NA WA 104
    rs20995391,2
    H70504838(-) GGGTCG/CAGGCC 1 -- int14Minor allele frequency- C:0.00NS EA 412
    rs58176991,2
    --70505493(+) GTGGG-/CTGGGT 1 -- int10--------
    rs58177001,2
    --70505548(+) caagg-/Ctggag 1 -- int10--------
    rs71882971,2
    C,F70494473(+) tggctA/Gatttt 1 -- int13Minor allele frequency- G:0.22NS WA 92
    rs71884741,2
    C,F,A70494496(+) agagaC/Tggggt 1 -- int13Minor allele frequency- T:0.22NS WA 90
    rs71888081,2
    C,F70494480(+) tttttG/Atattt 1 -- int12Minor allele frequency- A:0.20NS 90
    rs71914661,2
    --70491218(+) agtggC/Tgtgat 1 -- int10--------
    rs71928651,2
    C,F,A,70506907(+) GACCCC/TGAGAC 2 P syn1 ref123Minor allele frequency- T:0.34NS EA NA WA 1634
    rs71929361,2
    C,F,A,H,70494528(+) gtctcA/Gaactc 1 -- int13Minor allele frequency- G:0.27NS NA 94
    About this table

    HapMap Linkage Disequilibrium images for FUK (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for FUK
         1 CNV: 4965

    QIAGEN SeqTarget long-range PCR primers for resequencing FUK 

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    FUK for disorders           About GeneDecksing

    OMIM: 608675


    Export disorders and mutations for FUK gene to outside databases

    (Possibly Related Articles in Doctor's Guide)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    8 PubMed articles for FUK gene integrated from 7 sources:
    (articles sorted by number of sources associating them with FUK)
    1. Identification of human L-fucose kinase amino acid sequence. (PubMed id 12056818)1, 2, 3 Hinderlich S.... Bauer C. (2002)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1 Clark H.F.... Gray A.M. (2003)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    6. Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism. (PubMed id 11698403)7 Roos C.... Renkonen R. (2002)
    7. Activity of enzymes catalyzing formation of beta-L-fucosyl phosphate and GDP-beta-L-fucose in amphibian tissues and their application in chemo-enzymic synthesis of GDP-beta-L-fucose. (PubMed id 10424902)7 Druzhinina T.N....Shibaev V.N. (1999)
    8. Identification of new members of a carbohydrate kinase-encoding gene family. (PubMed id 8521274)7 Worley K.C....Smith R.F. (1995)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    OMIM
    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 197258 HGNC: 29500 AceView: FUK Ensembl:ENSG00000157353 euGenes: HUgn197258
    ECgene: FUK Kegg: 197258 H-InvDB: FUK

    (According to HUGE)
    About This Section
      --

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    ATLAS Chromosomes in Cancer entry for FUK Genetics and Cytogenetics in Oncology and Haematology
    SeattleSNPshttp://pga.gs.washington.edu/data/fuk/

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
    About This Section
    Patent Information for FUK gene:
    Search GeneIP for patents involving FUK

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
    Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
    About This Section

     Millipore Custom Antibody & Bulk Services
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     Predesigned and custom siRNAs for FUK Antibodies for FUK
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     Search for Antibodies & Assays

     Regulatory tfbs in FUK promoter
     Search Chromatin IP Primers for FUK
     RT2 qPCR Primer Assay for FUK
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     Assays for microRNAs that regulate FUK
     SABiosciences Custom PCR Arrays for FUK
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     Browse Sino Biological Proteins and Antibodies
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     Novus Tissue Slides
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     Browse antibodies at Epitomics
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     ELISAs and CLIAs for FUK
           

    GeneCards Homepage - Last full update: 31 Dec 2010 - Incremental updates: 10 Jan 2011 , 10 Jan 2011

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