Aliases &
Descriptions
for FUNDC2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| FUN14 domain containing 21 2 | | PD031042 | | HCBP61 2 3 | | cervical cancer oncogene 32 | | DC441 2 | | MGC1316762 | | Hepatitis C virus core-binding protein 62 3 | | FLJ337732 | | Cervical cancer proto-oncogene 3 protein2 3 | | MGC24952 | | HCC-32 3 | | HCC32 | | FUN14 domain-containing protein 22 | | |
Export aliases for FUNDC2 gene to outside databasesPrevious GC identifers: GC0XP153818 GC0XP153908 GC0XP154254 |
Summaries
for FUNDC2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Gene Wiki entry for FUNDC2 |
Genomic Views
for FUNDC2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FUNDC2 gene promoter:
GR-beta GR-alpha ATF-2 CREB Elk-1 C/EBPalpha C/EBPbeta NF-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for FUNDC2
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for FUNDC2  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq28 Ensembl cytogenetic band: Xq28 HGNC cytogenetic band: Xq28FUNDC2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP142800: view genomic region
(about GC identifiers)
Start:
|
142,800,036 bp from pter |
End:
|
142,830,182 bp from pter |
Size:
|
30,147 bases |
Orientation:
|
plus strand |
1 alternative location:
| ChrX+ 154,254,255-154,288,578 |
RefSeq DNA sequence:- NC_000023.10 NT_167198.1
|
Proteins
for FUNDC2 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: FUND2_HUMAN, Q9BWH2 (See
protein sequence)Recommended Name: FUN14 domain-containing protein 2 Size: 189 amino acids; 20676 Da
Sequence caution: Sequence=AAG44731.1; Type=Frameshift; Positions=69;
Secondary accessions: B2R7W5 Q8NHX8 Q9H2I6Explore the universe of human proteins at neXtProt for FUNDC2: NX_Q9BWH2
Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_076423.2
ENSEMBL proteins: ENSP00000358510 ENSP00000328546 ENSP00000395488
Human Recombinant Proteins
1 Gene Ontology (GO) cellular component term (GO ID links to tree view): About this table
FUNDC2 for ontologies About GeneDecksing
Antibodies for FUNDC2:
Assays for FUNDC2: |
Protein
Domains/
Families
for FUNDC2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FUNDC2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9BWH2ProtoNet protein and cluster: Q9BWH2 UniProtKB/Swiss-Prot: FUND2_HUMAN, Q9BWH2Similarity: Belongs to the FUN14 family |
Gene Function
for FUNDC2 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
|
Pathways & Interactions
for FUNDC2 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for FUNDC2
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FUNDC2
5/8 Interacting proteins for FUNDC2 (Q9BWH22) via UniProtKB, MINT, and/or STRING (see all 8)About this table
|
Drugs & Compounds
for FUNDC2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for FUNDC2
|
Transcripts
for FUNDC2 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for FUNDC2 gene: NM_023934.3 Additional cDNA sequence: AF267862.1 AF320778.1 AJ272054.1 AK056898.1 AK091092.1 AK129832.1 AK313143.1 AY032594.1 BC000255.1 BC072685.1 BC108657.1 CR591953.1 CR594530.1 CR596237.1 CR612292.1 CR612714.1 CR616296.1 CR616892.1 15 DOTS entries: DT.454648 DT.100030151 DT.100819935 DT.100030150 DT.75169753 DT.121312594 DT.92043594 DT.100030149 DT.92439185 DT.101956857 DT.121312418 DT.121312602 DT.75184711 DT.100030153 DT.91729072 24/351 AceView cDNA sequences (see all 351): CN482125 BM676502 BM991293 BM662690 AA588653 BU538909 BQ771960 CA389266 BI828286 BM855267 AI695529 BM668061 AW629783 BU752954 BM806389 AK091092 F35795 AA972572 BM970685 BM692542 AI610748 AA582220 BM800229 AA772764
 highest scoring ESTs for FUNDC2:AA081317 AA002210 AA047388 AA081069 AA083412 AA126891 AA128119 AA182888 AA291782 AA341866 Unigene Cluster for FUNDC2: FUN14 domain containing 2 Hs.356050 [show with all ESTs]Unigene Representative Sequence: AK091092
GeneLoc Exon Structure
8 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000485289 ENST00000369498(uc004fmw.2) ENST00000484175 ENST00000475165
ENST00000327891 ENST00000492303 ENST00000471528 ENST00000456179
|
Expression
for FUNDC2 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| FUNDC2 expression in normal and diseased human tissues
1 / 2 / 3 8 probe-sets matching FUNDC2 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 57202_at2, 3
|
U95-B |
2 |
1.00 |
0.91 |
0.93 |
1.49 |
AA081317 |
1.00 |
1.00 |
1.00 |
1 |
| 71414_at2, 3
|
U95-D |
1 |
0.81 |
1.00 |
0.88 |
0.98 |
AI886036 |
0.80 |
1.00 |
0.91 |
1 |
| 42370_at2, 3
|
U95-B |
1 |
0.81 |
1.00 |
0.63 |
0.32 |
AI458410 |
0.80 |
1.00 |
0.91 |
1 |
| 47828_r_at2, 3
|
U95-B |
1 |
0.44 |
1.00 |
0.95 |
0.55 |
H09739 |
0.40 |
1.00 |
0.76 |
1 |
| 223042_s_at2, 3
|
U133-B |
1 |
1.00 |
1.00 |
-- |
-- |
BC000255 |
0.80 |
1.00 |
0.91 |
1 |
| 230922_x_at2, 3
|
U133-B |
1 |
0.36 |
1.00 |
-- |
-- |
H09739 |
0.40 |
1.00 |
0.76 |
1 |
| 223042_s_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 230922_x_at2
|
U133Plus2 |
1 |
0.36 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
FUNDC2 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.356050
SABiosciences Custom PCR Arrays for FUNDC2
|
Orthologs
for FUNDC2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for FUNDC2 gene from 5/6 species (see all 6)
About this table Species with no ortholog for FUNDC2
ENSEMBL Gene Tree for FUNDC2 (if available) |
Paralogs
for FUNDC2 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for FUNDC2 gene
- FUNDC12
FUNDC2 for paralogs About GeneDecksing
Pseudogenes
- 3 related pseudogenes
|
Genomic Variants
for FUNDC2 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr X pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for FUNDC2 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for FUNDC2
1 CNV: 23331 | | QIAGEN SeqTarget long-range PCR primers for resequencing FUNDC2 |
|
Disorders & Mutations
for FUNDC2 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Medical News
for FUNDC2 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for FUNDC2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
10/15 PubMed articles for FUNDC2 gene, integrated from 7 sources (see all 15):
(articles sorted by number of sources associating them with FUNDC2)- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Screening and cloning gene of hepatocyte protein interacting with hepatitis C virus core protein (PubMed id 12665903)1, 2 Li K.... Chen J. (2002)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)2 Daub H.... Mann M. (2008)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)2 Olsen J.V....Mann M. (2006)
- The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (2006)
- The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (2005)
- A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
|
External Searches for FUNDC2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FUNDC2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FUNDC2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FUNDC2 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for FUNDC2 gene:
Search GeneIP for patents involving FUNDC2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FUNDC2 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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