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GOLGA6L9 Gene

protein-coding   GIFtS: 25

GC15P082722
golgin A6 family-like 9
(Previous names: golgi autoantigen, golgin subfamily a, 6-like 9 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases & Descriptions
golgin A6 family-like 91 2
golgi autoantigen, golgin subfamily a, 6-like 91 2
golgi autoantigen, golgin subfamily a, 6D-like2
Golgin subfamily A member 6-like protein 92

External Ids:    HGNC: 372291   Entrez Gene: 4402952   Ensembl: ENSG000001979787   UniProtKB: A6NEM13   

Export aliases for GOLGA6L9 gene to outside databases

Previous GC identifer: GC15P080512


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

  --

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for GOLGA6L9
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for GOLGA6L9

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q25.2   Ensembl cytogenetic band:  15q25.2   HGNC cytogenetic band: 15q25.2

GOLGA6L9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GOLGA6L9 gene location

GeneLoc gene densities for chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P082722:  view genomic region     (about GC identifiers)

Start:
82,722,185 bp from pter
End:
82,731,587 bp from pter
Size:
9,403 bases
Orientation:
plus strand

0 alternative location:

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: GG6L9_HUMAN, A6NEM1 (See protein sequence)
Recommended Name: Golgin subfamily A member 6-like protein 9  
Size: 432 amino acids; 49096 Da
Sequence caution: Sequence=AAH41854.1; Type=Erroneous initiation;
Secondary accessions: Q8IVV3
Alternative splicing: 2 isoforms:  A6NEM1-1   A6NEM1-2   

Explore the universe of human proteins at neXtProt for GOLGA6L9: NX_A6NEM1 

REFSEQ proteins: NP_937824.2  

ENSEMBL proteins: 
ENSP00000300515 ENSP00000341473 


Human Recombinant Proteins 
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Antibodies for GOLGA6L9: 
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Assays for GOLGA6L9: 
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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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ProtoNet protein and cluster: A6NEM1

UniProtKB/Swiss-Prot: GG6L9_HUMAN, A6NEM1
Similarity: Belongs to the GOLGA6 family


(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
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Inhib.
RNA:
    
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich siRNA for GOLGA6L9
Sigma-Aldrich shRNA for GOLGA6L9
OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): GOLGA6L9
OriGene shRNA RFP (see all 2): GOLGA6L9
OriGene basic RS shRNA (see all 2): GOLGA6L9
OriGene siRNA: GOLGA6L9
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of GOLGA6L9 
miRNA:Browse microRNA Mimics at Sigma-Aldrich
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of GOLGA6L9 
Search SABiosciences for Assays for microRNAs that regulate GOLGA6L9

Gene
Editing:
Browse CompoZr Knockout ZFN at Sigma-Aldrich 

Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
Browse iPSC Reprogramming Factors at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: GOLGA6L9
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: GOLGA6L9
OriGene untagged cDNA clones in CMV expression vector (see all 2): GOLGA6L9
OriGene 3'-UTR clone: GOLGA6L9 
Browse MicroRNA Expression Plasmids 
GenScript Custom cDNA clone Services for GOLGA6L9 
Browse Sino Biological Human cDNA Clones

Cell
Lines:
  
GenScript Custom overexpressing Cell Line Services for GOLGA6L9 


(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
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    SABiosciences Custom Pathway-Focused PCR Arrays for GOLGA6L9 

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GOLGA6L9

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section
Browse Small Molecules at Sigma-Aldrich
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for GOLGA6L9


(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib.
RNA:
     
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich siRNA for GOLGA6L9
Sigma-Aldrich shRNA for GOLGA6L9
OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): GOLGA6L9
OriGene shRNA RFP (see all 2): GOLGA6L9
OriGene basic RS shRNA (see all 2): GOLGA6L9
OriGene siRNA: GOLGA6L9
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of GOLGA6L9 
miRNA: Browse microRNA Mimics at Sigma-Aldrich
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of GOLGA6L9 
Search SABiosciences for Assays for microRNAs that regulate GOLGA6L9
Clones: Browse FLAG tag genes at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: GOLGA6L9
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: GOLGA6L9
OriGene untagged cDNA clones in CMV expression vector (see all 2): GOLGA6L9
OriGene 3'-UTR Clone: GOLGA6L9 
Browse OriGene MicroRNA Expression Plasmids 
GenScript Custom cDNA clone Services for GOLGA6L9 
Primers: OriGene genome-wide validated SYBR primer pairs: GOLGA6L9
Browse OriGene validated miRNA SYBR primer pairs 
Search SABiosciences RT2 qPCR Primer Assays for GOLGA6L9

REFSEQ mRNAs for GOLGA6L9 gene: 

NM_198181.2  

24/74 AceView cDNA sequences (see all 74):

BM698646 BQ638438 AK128268 AW206224 AI860513 BM980122 BM670739 BX509962 
BU675923 BM789384 BU685103 BM676751 AW946001 BC066934 AI205783 BG717020 
AW195066 AA370753 BU674158 AW946002 AL110434 AI802050 BC041854 BF761039 


GeneLoc Exon Structure

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000300515(uc002bha.1 uc010blt.2 uc002bhb.3) ENST00000342830


(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

GOLGA6L9 expression in normal and diseased human tissues

Data from GNF BioGPS
    About these images

GOLGA6L9 gene expression
GOLGA6L9 gene electronic northern expression
GOLGA6L9 gene sage expression
About these images

CGAP SAGE TAG: --
Primers: OriGene genome-wide validated SYBR primer pairs: GOLGA6L9
Browse OriGene validated miRNA SYBR primer pairs 
Search SABiosciences RT2 qPCR Primer Assays for GOLGA6L9
    SABiosciences Custom PCR Arrays for GOLGA6L9 


(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for GOLGA6L9 gene from 1 species
Organism Gene Locus Description Human
Similarity
NCBI accessions
chimpanzee
(Pan troglodytes)
LOC7438601   -- hypothetical protein LOC743860 84.07(n)
76.83(a)
743860  XM_001148057.1  XP_001148057.1 
About this table        Species with no ortholog for GOLGA6L9

ENSEMBL Gene Tree for GOLGA6L9 (if available)

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
Paralogs for GOLGA6L9 gene
LOC7286361 2  LOC647042  LOC642346  LOC643696  LOC161527  ENSG000002203562  ENSG000001886262  GOLGA8E2  
GOLGA8G2  ENSG000002250332  GOLGA8F2  ENSG000002139742  GOLGA8DP2  ENSG000002143942  GOLGA6B2  GOLGA6A2  
ENSG000002053152  GOLGA8J2  LOC6423252  LOC7280472  GOLGA22  ENSG000002326532  GOLGA6L42  LOC4417362  
ENSG000001878122  ENSG000001671412  GOLGA8H2  ENSG000001038322  ENSG000001781152  GOLGA8C2  GOLGA6C2  LOC6436992  
LOC1002892892  ENSG000002499312  GOLGA8B2  GOLGA8A2  GOLGA6L102  LOC6530612  ENSG000002352762  GOLGA6D2  

GOLGA6L9 for paralogs           About GeneDecksing



(SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 15 variations for GOLGA6L9
     15 CNVs: 77020 30717 87772 77019 77021 30716 3972 72314 72323 87771 87770 2197 72309 7074 0788
Search QIAGEN SeqTarget long-range PCR primers for resequencing for GOLGA6L9 

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section
  --

(Possibly Related Articles in Doctor's Guide)
About This Section
  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
About This Section

3 PubMed articles for GOLGA6L9 gene integrated from 7 sources:
(articles sorted by number of sources associating them with GOLGA6L9)
  1. Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)2 Zody M.C....Nusbaum C. (2006)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 440295 HGNC: 37229 AceView: LOC440295 Ensembl:ENSG00000197978 euGenes: HUgn440295
ECgene: GOLGA6L9 H-InvDB: GOLGA6L9

(According to HUGE)
About This Section
  --

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
  --

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from XenneX, Inc.)
About This Section
Patent Information for GOLGA6L9 gene:
Search GeneIP for patents involving GOLGA6L9

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
About This Section

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 "Your Favorite Gene" Pathways and Molecular Interaction Networks Browse Nano Scale siRNA at Sigma-Aldrich
 Browse iPSC Reprogramming Factors at Sigma-Aldrich Browse small molecules at Sigma-Aldrich
 Browse FLAG tag genes at Sigma-Aldrich Browse ELISAs at Sigma-Aldrich
 Browse microRNA Target Validation Systems at Sigma-Aldrich Browse CompoZr Knockout ZFN at Sigma-Aldrich
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 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of GOLGA6L9
 Search QIAGEN SeqTarget long-range PCR primers for resequencing for GOLGA6L9
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of GOLGA6L9
 GenScript Custom Purified and Recombinant Proteins Services for GOLGA6L9 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for GOLGA6L9
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 Browse ELISAs and CLIAs at Uscn
       

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