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GPER Gene

protein-coding   GIFtS: 51

GC07P001041
G protein-coupled estrogen receptor 1
(Previous name: G protein-coupled receptor 30 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbols: CMKRL2, GPR30)
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
G protein-coupled estrogen receptor 11 2     Lymphocyte-derived G-protein coupled receptor2 3
DRY121 2 3     mER2 3
CEPR1 2 3     G-protein coupled receptor 302 3
FEG-11 2 3     IL8-related receptor DRY122 3
GPR302 3 5     OTTHUMP000002000792
CMKRL22 3 5     constitutively expressed peptide-like receptor2
LyGPR1 2     G-protein coupled estrogen receptor 12
GPCR-Br1 2     heptahelix receptor2
LERGU1 2     leucine rich protein in GPR30 3'UTR2
G protein-coupled receptor 301 2     MGC996782
LERGU21 2     chemokine receptor-like 22
Membrane estrogen receptor2 3     LYGPR3
Flow-induced endothelial G-protein coupled receptor 12 3     GPCR-BR3
Chemoattractant receptor-like 22 3     

External Ids:    HGNC: 44851   Entrez Gene: 28522   Ensembl: ENSG000001648507   UniProtKB: Q995273   

Export aliases for GPER gene to outside databases

Previous GC identifers: GC07P001093 GC07P001121


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GPER:
This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that
localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization
and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the
rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate
transcriptional splice variants which encode the same protein have been characterized. (provided by RefSeq)

UniProtKB/Swiss-Prot: GPER_HUMAN, Q99527
Function: Receptor for estrogen

summary for GPER:
The GPR30 receptor is an orphan G-protein-coupled receptor that has recently been shown to bind estrogen and
cause estrogen-mediated adenylyl cyclase stimulation. GPR30 is widely distributed in neural, breast cancer,
placental, heart, ovarian, prostate, hepatic, vascular epithelial and lymphoid tissue. The receptor acts
independently of ERalpha and ERbeta and triggers ER-dependent EGFR action.

Gene Wiki entry for GPER (GPR30)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for GPER
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for GPER

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for GPER 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p22.3   Ensembl cytogenetic band:  7p22.3   HGNC cytogenetic band: 7p22

GPER Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GPER gene location

GeneLoc gene densities for chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P001041:  view genomic region     (about GC identifiers)

Start:
1,041,713 bp from pter
End:
1,048,693 bp from pter
Size:
6,981 bases
Orientation:
plus strand

1 alternative location:
Chr7+ 1,121,844-1,133,451     
RefSeq DNA sequence:
NC_000007.13  NT_007819.17  NT_079592.2  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: GPER_HUMAN, Q99527 (See protein sequence)
Recommended Name: G-protein coupled estrogen receptor 1  
Size: 375 amino acids; 42248 Da
Subcellular location: Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane
protein (By similarity). Golgi apparatus membrane; Multi-pass membrane protein (By similarity). Note=Protein has been
detected in the cell membrane, endoplasmic reticulum and Golgi apparatus. It is currently unclear whether this is a
cell surface or intracellular receptor
Secondary accessions: A8K6C5 B5BUJ1 O00143 O43494 Q13631 Q6FHL1 Q96F42 Q99981

Explore the universe of human proteins at neXtProt for GPER: NX_Q99527 

REFSEQ proteins (3 alternative transcripts): 
NP_001035055.1  NP_001091671.1  NP_001496.1  


ENSEMBL proteins: 
ENSP00000380281 ENSP00000341512 ENSP00000380277 ENSP00000346586 ENSP00000410487 ENSP00000385151 
ENSP00000297469 


Human Recombinant Proteins 
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OriGene Protein Over-expression Lysate: GPER
GenScript Custom Purified and Recombinant Proteins Services for GPER 
Novus Biologicals Proteins for GPER
Browse Sino Biological Recombinant Proteins
Browse ProSpec Recombinant Proteins

5/7 Gene Ontology (GO) cellular component terms (GO ID links to tree view) (see all 7):

GO IDQualified GO termEvidencePubMed IDs
GO:0000139 Golgi membrane IEA--
GO:0005783 endoplasmic reticulum IEA--
GO:0005789 endoplasmic reticulum membrane IEA--
GO:0005794 Golgi apparatus IEA--
GO:0005886 plasma membrane TAS--
About this table

GPER for ontologies           About GeneDecksing



Antibodies for GPER: 
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Epitomics antibodies for GPER

Assays for GPER: 
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GenScript Custom Assay Services for GPER 
Browse Enzo Life Sciences for kits & assays
Uscn ELISAs and CLIAs for GPER 


(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

GPER for domains           About GeneDecksing

3 InterPro domains/families:
 IPR017452 GPCR_Rhodpsn_supfam
 IPR015692 GPR30
 IPR000276 7TM_GPCR_Rhodpsn

Graphical View of Domain Structure for InterPro Entry Q99527

ProtoNet protein and cluster: Q99527

UniProtKB/Swiss-Prot: GPER_HUMAN, Q99527
Similarity: Belongs to the G-protein coupled receptor 1 family


(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: GPER_HUMAN, Q99527
Function: Receptor for estrogen

Inhib.
RNA:
    
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich siRNA Panels and siRNA for GPER
Sigma-Aldrich shRNA Panels and shRNA for GPER
OriGene 29mer shRNA kits in GFP-retroviral vector (see all 4): GPER
OriGene shRNA RFP (see all 4): GPER
OriGene basic RS shRNA (see all 4): GPER
OriGene siRNA (see all 3): GPER
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of GPER 
miRNA:Browse microRNA Mimics at Sigma-Aldrich
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of GPER 
Search SABiosciences for Assays for microRNAs that regulate GPER

Gene
Editing:
Browse CompoZr Knockout ZFN at Sigma-Aldrich 

Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
Browse iPSC Reprogramming Factors at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): GPER
OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): GPER
OriGene untagged cDNA clones in CMV expression vector (see all 3): GPER
OriGene 3'-UTR clone (see all 3): GPER 
Browse MicroRNA Expression Plasmids 
GenScript Custom cDNA clone Services for GPER 
Sino Biological Human cDNA Clone for GPER

Cell
Lines:
  
GenScript Custom overexpressing Cell Line Services for GPER 

2 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0004872 receptor activity IEA--
GO:0004930 G-protein coupled receptor activity IEA--
About this table

GPER for ontologies           About GeneDecksing

Animal Models: 11 MGI mutant phenotypes (inferred from 5 alleles(MGI details for Gpr30):

cardiovascular systemendocrine/exocrine glandgrowth/sizehematopoietic systemhomeostasis/metabolism
immune systemlimbs/digits/tailliver/biliary systemno phenotypic analysisreproductive system
skeleton

GPER for phenotypes           About GeneDecksing


(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section


GPER for pathways           About GeneDecksing

1 Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Pathway for  GPER
    G-Protein Coupled Receptor Signaling

    SABiosciences Pathway-Focused PCR Array including GPER: PAHS-3009A 

    Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Molecular Interaction Network for GPER
    SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for GPER

1 Gene Ontology (GO) biological process term (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0007186 G-protein coupled receptor protein signaling pathway TAS8920907
About this table

GPER for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

GPER for compounds           About GeneDecksing

Sigma-Aldrich Small Molecules for GPER:
Small Molecule - Agonist/Antagonist
Browse drugs & compounds from Enzo Life Sciences

Compounds for GPER available from Tocris Bioscience
CompoundAction CAS number
beta-EstradiolEndogenous ER agonist[50-28-2]
Tamoxifen citrateEstrogen receptor partial agonist/antagonist[54965-24-1]
ICI 182,780 Estrogen receptor antagonist[129453-61-8]
G-15High affinity and selective GPR30 antagonist[1161002-05-6]
About this table


6 Novoseek chemical compound relationships for GPER gene
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
estrogen 74.6 77 18467441 (5), 11043579 (4), 18420744 (4), 19749156 (4) (see all 27)
progestin 62.6 16 12193550 (8), 12446589 (2), 15539556 (1), 16289637 (1)
estradiol 48.4 1 18566127 (1)
steroid 44.2 7 20228382 (1), 17640985 (1), 18420744 (1), 15511221 (1) (see all 5)
progesterone 35 2 20228382 (1), 12193550 (1)
calcium 17.9 2 19131510 (1)
About this table



(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib.
RNA:
     
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich siRNA Panels and siRNA for GPER
Sigma-Aldrich shRNA Panels and shRNA for GPER
OriGene 29mer shRNA kits in GFP-retroviral vector (see all 4): GPER
OriGene shRNA RFP (see all 4): GPER
OriGene basic RS shRNA (see all 4): GPER
OriGene siRNA (see all 3): GPER
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of GPER 
miRNA: Browse microRNA Mimics at Sigma-Aldrich
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of GPER 
Search SABiosciences for Assays for microRNAs that regulate GPER
Clones: Browse FLAG tag genes at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): GPER
OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): GPER
OriGene untagged cDNA clones in CMV expression vector (see all 3): GPER
OriGene 3'-UTR Clone (see all 3): GPER 
Browse OriGene MicroRNA Expression Plasmids 
GenScript Custom cDNA clone Services for GPER 
Primers: OriGene genome-wide validated SYBR primer pairs: GPER
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for GPER: PPH11263A

REFSEQ mRNAs for GPER gene (3 alternative transcripts): 

NM_001039966.1  NM_001098201.1  NM_001505.2  

Additional cDNA sequence: 

AB451427.1 AF015257.1 AK289588.1 AY265807.1 AY265808.1 AY265809.1 BC011634.1 BC067849.1 
BC082766.1 CR541655.1 CR541741.1 U58828.1 U63917.1 X98510.1 Y08162.1 

6 DOTS entries:

DT.100691243  DT.101963730  DT.95371254  DT.112109  DT.91758727  DT.100790769 

24/75 AceView cDNA sequences (see all 75):

BQ278731 CB106598 BU732605 BU857553 BU857973 BX101291 BC082766 U63917 
Y08162 BI820958 X98510 AA810225 CD558521 BM016871 AY265807 BM680243 
CB995575 BF941220 CF994734 AY265809 BX956912 CB991744 BE874882 BE677759 

Unigene Cluster for GPER:

G protein-coupled estrogen receptor 1
Hs.20961  [show with all ESTs]
Unigene Representative Sequence: NM_001039966


GeneLoc Exon Structure

7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000397092(uc010ksd.1 uc003sjz.1 uc003ska.1) ENST00000342452
ENST00000397088(uc003skb.2) ENST00000354575 ENST00000413368 ENST00000401670
ENST00000297469

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

GPER expression in normal and diseased human tissues

1  / 2

5 probe-sets matching GPER gene

Affymetrix
probe-set
Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
37447_at2 U95-A 1 1.00 1.00 1.00 1.00 -- -- -- -- --
210640_s_at2 U133-A 1 1.00 1.00 -- -- -- -- -- -- --
211829_s_at2 U133-A 1 1.00 1.00 -- -- -- -- -- -- --
210640_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
211829_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
About this table

GPER for expression           About GeneDecksing

Data from Genenote  (Publications) and GNF BioGPS
    About these images
GPER gene expression
GPER gene electronic northern expression
GPER gene sage expression
About these images

CGAP SAGE TAG: TGCGGAAAAA

SOURCE GeneReport for Unigene cluster: Hs.20961

UniProtKB/Swiss-Prot: GPER_HUMAN, Q99527
Tissue specificity: Ubiquitously expressed, but is most abundant in placenta. In brain regions, expressed as a 2.8 kb
transcript in basal forebrain, frontal cortex, thalamus, hippocampus, caudate and putamen

Primers: OriGene genome-wide validated SYBR primer pairs: GPER
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for GPER: PPH11263A
    SABiosciences Expression via Pathway-Focused PCR Array including GPER: PAHS-3009A 


(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for GPER gene from 5/7 species (see all 7)
Organism Gene Locus Description Human
Similarity
NCBI accessions
dog
(Canis familiaris)
GPER1   -- G protein-coupled estrogen receptor 1 86.49(n)
89.73(a)
480808  XM_537923.2  XP_537923.2 
chimpanzee
(Pan troglodytes)
GPER1   -- G protein-coupled estrogen receptor 1 99.47(n)
100(a)
463215  XM_001145483.1  XP_001145483.1 
cow
(Bos taurus)
GPER1   -- G protein-coupled estrogen receptor 1 84.95(n)
84.29(a)
527831  XM_606236.3  XP_606236.3 
rat
(Rattus norvegicus)
Gper1   -- G protein-coupled estrogen receptor 1 84(n)
86.13(a)
171104  NM_133573.1  NP_598257.1 
mouse
(Mus musculus)
Gpr305
Gper1
5 (78.58 cM)5
G protein-coupled receptor 305
G protein-coupled estrogen receptor 11
84.44(n)1
86.67(a)1
768541  NM_029771.21  NP_084047.11 
 AK0182035  AK0303755  (see all 9)
About this table        Species with no ortholog for GPER

ENSEMBL Gene Tree for GPER (if available)

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
Paralogs for GPER gene
GPR1462  

GPER for paralogs           About GeneDecksing



(SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for GPER
     2 CNVs: 0093 4519
QIAGEN SeqTarget long-range PCR primers for resequencing GPER 

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section

GPER for disorders           About GeneDecksing

OMIM: 601805

4 Novoseek disease relationships for GPER gene

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
breast cancer 48.8 26 18467441 (3), 12027886 (2), 18768737 (2), 19342448 (2) (see all 12)
ovarian cancer 22.1 3 17308128 (3), 19395996 (1)
tumors 15.2 7 18467441 (2), 11043579 (1), 19951611 (1), 19749156 (1) (see all 5)
cancer 0.465 5 19951611 (1), 19749156 (1), 17308128 (1), 19432902 (1)
About this table

Human Genome Epidemiology (HuGE) Navigator: GPER (2 documents)

Export disorders and mutations for GPER gene to outside databases

(Possibly Related Articles in Doctor's Guide)
About This Section
  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
About This Section

10/86 PubMed articles for GPER gene, integrated from 7 sources (see all 86):
(articles sorted by number of sources associating them with GPER)
  1. Discovery of three novel G-protein-coupled receptor genes. (PubMed id 9479505)1, 2, 3 O'Dowd B.F.... George S.R. (1998)
  2. Identification of a gene (GPR30) with homology to the G-protein- coupled receptor superfamily associated with estrogen receptor expression in breast cancer. (PubMed id 9367686)1, 2, 7 Carmeci C.... Weigel R.J. (1997)
  3. Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans- activation of the epidermal growth factor receptor through release of HB-EGF. (PubMed id 11043579)1, 2, 7 Filardo E.J.... Frackelton A.R. Jr. (2000)
  4. Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. (PubMed id 15539556)1, 2, 7 Thomas P.... Dong J. (2005)
  5. Synthetic estrogen derivatives demonstrate the functionality of intracellular GPR30. (PubMed id 17655271)1, 3 Revankar C.M....Prossnitz E.R. (2007)
  6. A transmembrane intracellular estrogen receptor mediates rapid cell signaling. (PubMed id 15705806)1, 2 Revankar C.M....Prossnitz E.R. (2005)
  7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  8. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
  9. Cloning of cDNAs encoding G protein-coupled receptor expressed in human endothelial cells exposed to fluid shear stress. (PubMed id 9398636)1, 2 Takada Y.... Ando J. (1997)
  10. A novel putative G-protein-coupled receptor expressed in lung, heart and lymphoid tissue. (PubMed id 9141481)1, 2 Kvingedal A.M. and Smeland E.B. (1997)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Disorders
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 2852 HGNC: 4485 AceView: GPR30 Ensembl:ENSG00000164850 euGenes: HUgn2852
ECgene: GPER H-InvDB: GPER

(According to HUGE)
About This Section
  --

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
  --

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from XenneX, Inc.)
About This Section
Patent Information for GPER gene:
Search GeneIP for patents involving GPER

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
About This Section

 Millipore Custom Antibody & Bulk Services
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 Predesigned and custom siRNAs for GPER Antibodies for GPER
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 Browse FLAG tag genes at Sigma-Aldrich Browse ELISAs at Sigma-Aldrich
 Browse microRNA Target Validation Systems at Sigma-Aldrich Browse CompoZr Knockout ZFN at Sigma-Aldrich
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 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of GPER
 SeqTarget long-range PCR primers for resequencing GPER
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for GPER
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of GPER
 GenScript Custom Purified and Recombinant Proteins Services for GPER GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for GPER
 GenScript Custom Assay Services for GPER GenScript Superior Antibodies for GPER
 GenScript Custom overexpressing Cell Line Services for GPER CloneReady with Over 120,000 Genes
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 ELISAs and CLIAs for GPER
       

GeneCards Homepage - Last full update: 31 Dec 2010 - Incremental updates: 9 Jan 2011 , 10 Jan 2011

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