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GTF2E1 Gene

protein-coding   GIFtS: 58

GC03P117835
general transcription factor IIE, polypeptide 1, alpha 56kDa
(Previous names: general transcription factor IIE, polypeptide 1 (alpha subunit, 56kD) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
general transcription factor IIE, polypeptide 1, alpha 56kDa1 2     TFIIE-alpha2 3
FE1 2     TF2E12 3
TFIIE-A1 2     general transcription factor IIE, polypeptide 1 (alpha subunit, 56kD)1
Transcription initiation factor IIE subunit alpha2 3     general transcription factor IIE subunit 12
General transcription factor IIE 56 kDa subunit2 3     

External Ids:    HGNC: 46501   Entrez Gene: 29602   Ensembl: ENSG000001537677   UniProtKB: P290833   

Export aliases for GTF2E1 gene to outside databases

Previous GC identifers: GC03P117106 GC03P120110 GC03P121742 GC03P121790 GC03P121952 GC03P120461


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: T2EA_HUMAN, P29083
Function: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and
DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GTF2E1 gene promoter:
         C/EBPbeta   E4BP4   AREB6   CREB   deltaCREB   Nkx3-1 v1   Nkx3-1 v2   Nkx3-1   Nkx3-1 v3   Nkx3-1 v4   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for GTF2E1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q21-q24   Ensembl cytogenetic band:  3q13.33   HGNC cytogenetic band: 3q21-q24

GTF2E1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GTF2E1 gene location

GeneLoc gene densities for chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P117835:  view genomic region     (about GC identifiers)

Start:
117,835,641 bp from pter
End:
117,875,998 bp from pter
Size:
40,358 bases
Orientation:
plus strand

1 alternative location:
Chr3+ 120,461,484-120,501,916     
RefSeq DNA sequence:
NC_000003.11  NT_005612.16  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: T2EA_HUMAN, P29083 (See protein sequence)
Recommended Name: General transcription factor IIE subunit 1  
Size: 439 amino acids; 49452 Da
Subunit: Tetramer of two alpha and two beta chains. Interacts with TAF6/TAFII80. Interacts with varicella-zoster virus
IE63 protein
Subcellular location: Nucleus
PDB structures from and Proteopedia :
1VD4 (3D)    2JTX (3D)    2RNQ (3D)    2RNR (3D)    
Secondary accessions: Q16103

Explore the universe of human proteins at neXtProt for GTF2E1: NX_P29083 

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_005504.2  

    ENSEMBL proteins: 
    ENSP00000417077 ENSP00000283875 ENSP00000418808 ENSP00000417342 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: GTF2E1
    GenScript Custom Purified and Recombinant Proteins Services for GTF2E1 
    Novus Biologicals Proteins for GTF2E1
    Novus Biologicals Lysate for GTF2E1
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins

    2 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634 nucleus IEA--
    GO:0005654 nucleoplasm TAS--
    About this table

    GTF2E1 for ontologies           About GeneDecksing



    Antibodies for GTF2E1: 
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for GTF2E1
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    GenScript Custom Superior Antibodies Services for GTF2E1 
    Novus Biologicals Antibodies for GTF2E1
    Browse antibodies at Epitomics

    Assays for GTF2E1: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for GTF2E1 
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for GTF2E1 


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    GTF2E1 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR013083 Znf_RING/FYVE/PHD
     IPR002853 TFIIE_asu
     IPR021600 TFIIE_asu_C_met
     IPR017919 TFIIE/TFIIEa_HTH
     IPR013137 Znf_TFIIB

    Graphical View of Domain Structure for InterPro Entry P29083

    ProtoNet protein and cluster: P29083

    1 Blocks protein family: IPB002853 Transcription factor TFIIE

    UniProtKB/Swiss-Prot: T2EA_HUMAN, P29083
    Similarity: Belongs to the TFIIE alpha subunit family
    Similarity: Contains 1 HTH TFE/IIEalpha-type domain


    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    UniProtKB/Swiss-Prot: T2EA_HUMAN, P29083
    Function: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and
    DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase

    Inhib.
    RNA:
        
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for GTF2E1
    Sigma-Aldrich shRNA for GTF2E1
    OriGene 29mer shRNA kits in GFP-retroviral vector: GTF2E1
    OriGene shRNA RFP: GTF2E1
    OriGene basic RS shRNA: GTF2E1
    OriGene siRNA: GTF2E1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of GTF2E1 
    miRNA:Sigma-Aldrich microRNA Mimics for GTF2E1
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of GTF2E1 
    8 SABiosciences Assays for microRNAs that regulate GTF2E1:
    hsa-miR-200c hsa-miR-124 hsa-miR-300 hsa-miR-429 hsa-miR-381 hsa-miR-506 hsa-miR-222 hsa-miR-221

    Gene
    Editing:
    Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: GTF2E1
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: GTF2E1
    OriGene untagged cDNA clones in CMV expression vector: GTF2E1
    OriGene 3'-UTR clone: GTF2E1 
    Browse MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for GTF2E1 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:
      
    GenScript Custom overexpressing Cell Line Services for GTF2E1 

    Genatlas biochemistry entry for GTF2E1:
    general transcription factor IIE,alpha polypeptide (56kDa)

    4 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003702 RNA polymerase II transcription factor activity IEA--
    GO:0005515 protein binding IPI7926747
    GO:0008270 zinc ion binding IEA--
    GO:0046872 metal ion binding IEA--
    About this table

    GTF2E1 for ontologies           About GeneDecksing


    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section


    GTF2E1 for pathways           About GeneDecksing

    3 Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Pathways for  GTF2E1
        Glucocorticoid Receptor Signaling
    Androgen Signaling
    Estrogen Receptor Signaling

    1 Kegg Pathway  (Kegg details for GTF2E1):
        hsa03022 Basal transcription factors

        SABiosciences Custom Pathway-Focused PCR Arrays for GTF2E1 

        Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Molecular Interaction Network for GTF2E1
        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GTF2E1

    5/74 Interacting proteins for GTF2E1 (P290832 ENSP000002838753) via UniProtKB, MINT, and/or STRING (see all 74)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GTF2H1P327802, ENSP000002659633MINT-6543860 MINT-6544144 MINT-6543809 MINT-6543875 MINT-6544058 MINT-6544043 MINT-6544016 MINT-6543846 MINT-6544109 MINT-6543950 MINT-6543970 MINT-6544074 MINT-6544091 MINT-6543893 MINT-6543913 MINT-6543931 MINT-6543998 MINT-6543827 MINT-6544126 STRING: ENSP00000265963
    GTF2E2P290842, ENSP000003481683MINT-1894096 MINT-1894113 STRING: ENSP00000348168
    TBPENSP000002303543STRING: ENSP00000230354
    CDK7ENSP000002564433STRING: ENSP00000256443
    ERCC2ENSP000002214813STRING: ENSP00000221481
    About this table

    5/8 Gene Ontology (GO) biological process terms (GO ID links to tree view) (see all 8):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006350 transcription TAS--
    GO:0006366 transcription from RNA polymerase II promoter TAS--
    GO:0006367 transcription initiation from RNA polymerase II promoter TAS--
    GO:0006368 RNA elongation from RNA polymerase II promoter EXP9405375
    GO:0010467 gene expression TAS--
    About this table

    GTF2E1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section
    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GTF2E1


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section

    Inhib.
    RNA:
         
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for GTF2E1
    Sigma-Aldrich shRNA for GTF2E1
    OriGene 29mer shRNA kits in GFP-retroviral vector: GTF2E1
    OriGene shRNA RFP: GTF2E1
    OriGene basic RS shRNA: GTF2E1
    OriGene siRNA: GTF2E1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of GTF2E1 
    miRNA: Sigma-Aldrich microRNA Mimics for GTF2E1
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of GTF2E1 
    8 SABiosciences Assays for microRNAs that regulate GTF2E1:
    hsa-miR-200c hsa-miR-124 hsa-miR-300 hsa-miR-429 hsa-miR-381 hsa-miR-506 hsa-miR-222 hsa-miR-221
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: GTF2E1
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: GTF2E1
    OriGene untagged cDNA clones in CMV expression vector: GTF2E1
    OriGene 3'-UTR Clone: GTF2E1 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for GTF2E1 
    Primers: OriGene genome-wide validated SYBR primer pairs: GTF2E1
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for GTF2E1: PPH12554A

    REFSEQ mRNAs for GTF2E1 gene: 

    NM_005513.2  

    Additional cDNA sequence: 

    AK223401.1 BC005917.1 S67859.1 X63468.1 

    4 DOTS entries:

    DT.120868996  DT.95261900  DT.95261902  DT.412523 

    24/39 AceView cDNA sequences (see all 39):

    AA424864 BX102240 AA455964 AA243767 AW291752 BP343126 AW148448 AI800655 
    AL135122 BG571275 BE844117 AI039366 BE786346 AA455437 AI038742 AI167580 
    BF349423 BU954321 BF591217 AA453363 AA778149 BC005917 NM_005513 X63468 

    highest scoring ESTs for GTF2E1:

    X63468 AA243782 AA309888 AA424864 AA453363 AA455437 AA732517 BE786346 BF573188 BG571275 

    Unigene Cluster for GTF2E1:

    General transcription factor IIE, polypeptide 1, alpha 56kDa
    Hs.445272  [show with all ESTs]
    Unigene Representative Sequence: NM_005513


    GeneLoc Exon Structure

    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000492959 ENST00000283875(uc003edz.3) ENST00000497393(uc003edy.2)
    ENST00000469772 ENST00000484715

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    GTF2E1 expression in normal and diseased human tissues

    1  / 2  / 3

    3 probe-sets matching GTF2E1 gene

    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    37882_at2, 3 U95-A 1 0.75 1.00 1.00 1.00 X63468 1.00 1.00 1.00 1
    205930_at2, 3 U133-A 1 0.64 1.00 -- -- NM_005513 0.60 1.00 0.82 1
    205930_at2 U133Plus2 1 0.64 1.00 -- -- -- -- -- -- --
    About this table

    GTF2E1 for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    GTF2E1 gene expression
    GTF2E1 gene electronic northern expression
    GTF2E1 gene sage expression
    About these images

    CGAP SAGE TAG: TAAAGAATAT

    SOURCE GeneReport for Unigene cluster: Hs.445272

    Expression variation in blood from EXPOLDB for GTF2E1

    Primers: OriGene genome-wide validated SYBR primer pairs: GTF2E1
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for GTF2E1: PPH12554A
        SABiosciences Custom PCR Arrays for GTF2E1 


    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section

    Orthologs for GTF2E1 gene from 5/12 species (see all 12)
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    GTF2E11   -- general transcription factor IIE, polypeptide 1, alpha more 92.85(n)
    96.35(a)
    488002  XM_851885.1  XP_856978.1 
    chimpanzee
    (Pan troglodytes)
    GTF2E11   -- general transcription factor IIE, polypeptide 1, alpha more 99.24(n)
    99.09(a)
    460615  XM_516676.2  XP_516676.2 
    rat
    (Rattus norvegicus)
    Gtf2e11   -- general transcription factor IIE, polypeptide 1, alpha 88.43(n)
    93.15(a)
    303918  XM_221426.3  XP_221426.1 
    mouse
    (Mus musculus)
    Gtf2e11 , 5 16 (26.38 cM)5
    general transcription factor II E, polypeptide 1 (alpha more1, 5 88.69(n)1
    92.94(a)1
    741971  NM_028812.21  NP_083088.11 
     AI3038005  AI4475665  (see all 14)
    chicken
    (Gallus gallus)
    GTF2E11   -- general transcription factor IIE, polypeptide 1, alpha more 74.87(n)
    81.55(a)
    418328  XM_416551.2  XP_416551.2 
    About this table        Species with no ortholog for GTF2E1

    ENSEMBL Gene Tree for GTF2E1 (if available)

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
      --

    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/298 NCBI SNPs in GTF2E1 are shown (see all 298)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 3 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ----------
    rs2251791,2
    C,H120481016(-) ctcagC/Aaccac 1 -- int13Minor allele frequency- A:0.00NA 6
    rs3785611,2
    C,F,O,120493250(-) TTTTCG/AAACTT 1 -- int114Minor allele frequency- A:0.05EA NA NS 878
    rs3787591,2
    C,F,O,A,120485709(-) GGACAC/TGGAAA 1 -- int114Minor allele frequency- T:0.26EA NA NS WA 974
    rs4395961,2
    H120491010(-) AAATAG/AGACAC 1 -- int14Minor allele frequency- A:0.00NS EA 418
    rs4479781,2
    C,F,H,120491086(+) TGGCTA/GCAATT 1 -- int119Minor allele frequency- G:0.16NS EA NA WA 1390
    rs5379221,2
    C120479207(-) gacatC/Gattgt 1 -- int10--------
    rs8631661,2
    H120487707(-) ATATTT/GGGTAA 1 -- int14Minor allele frequency- G:0.00NS EA 420
    rs10561951,2
    --120501085(+) GCTTAG/TAATTT 1 -- ut310--------
    rs10702981,2
    C,H,120479504(-) aaaggC/Tctttg 1 -- int11Minor allele frequency- T:0.00NA 2
    rs14669601,2
    C,F,A,H,120465622(+) tctggG/Acaaca 1 -- int19Minor allele frequency- A:0.12NS EA NA WA 586
    About this table

    HapMap Linkage Disequilibrium images for GTF2E1 (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for GTF2E1: --

    QIAGEN SeqTarget long-range PCR primers for resequencing GTF2E1 

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    GTF2E1 for disorders           About GeneDecksing

    OMIM: 189962

    Human Gene Mutation Database (HGMD): GTF2E1
    Human Genome Epidemiology (HuGE) Navigator: GTF2E1 (1 document)

    Export disorders and mutations for GTF2E1 gene to outside databases

    (Possibly Related Articles in Doctor's Guide)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/49 PubMed articles for GTF2E1 gene, integrated from 7 sources (see all 49):
    (articles sorted by number of sources associating them with GTF2E1)
    1. Evolutionary conservation of human TATA-binding-polypeptide- associated factors TAFII31 and TAFII80 and interactions of TAFII80 with other TAFs and with general transcription factors. (PubMed id 7667268)1, 2 Hisatake K.... Roeder R.G. (1995)
    2. Genes encoding general initiation factors for RNA polymerase II transcription are dispersed in the human genome. (PubMed id 8162052)1, 3 Heng H.H....Tsui L.C. (1994)
    3. Identification of two large subdomains in TFIIE-alpha on the basis of homology between Xenopus and human sequences. (PubMed id 1454543)1, 3 Ohkuma Y....Horikoshi M. (1992)
    4. Structural motifs and potential sigma homologies in the large subunit of human general transcription factor TFIIE. (PubMed id 1956403)1, 2 Ohkuma Y....Roeder R.G. (1991)
    5. Structure and functional properties of human general transcription factor IIE. (PubMed id 1956398)1, 2 Peterson M.G.... Tjian R. (1991)
    6. p53 and TFIIEalpha share a common binding site on the Tfb1/p62 subunit of TFIIH. (PubMed id 18160537)1, 7 Di Lello P....Omichinski J.G. (2008)
    7. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (2010 Mar 5)
    8. Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study. (PubMed id 18950845)1 Vega A....Carracedo A. (2009)
    9. MCAF1/AM is involved in Sp1-mediated maintenance of cancer-associated telomerase activity. (PubMed id 19106100)1 Liu L....Nakao M. (2009)
    10. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 2960 HGNC: 4650 AceView: GTF2E1 Ensembl:ENSG00000153767 euGenes: HUgn2960
    ECgene: GTF2E1 Kegg: 2960 H-InvDB: GTF2E1

    (According to HUGE)
    About This Section
      --

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
      --

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
    About This Section
    Patent Information for GTF2E1 gene:
    Search GeneIP for patents involving GTF2E1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
    Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
    About This Section

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
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     Browse iPSC Reprogramming Factors at Sigma-Aldrich Browse small molecules at Sigma-Aldrich
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     Search for Antibodies & Assays

     Regulatory tfbs in GTF2E1 promoter
     Search Chromatin IP Primers for GTF2E1
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     Search GNC Networks for GTF2E1
     Assays for microRNAs that regulate GTF2E1
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     Browse Sino Biological Proteins and Antibodies
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     Novus Tissue Slides
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     Browse antibodies at Epitomics
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     ELISAs and CLIAs for GTF2E1
           

    GeneCards Homepage - Last full update: 31 Dec 2010 - Incremental updates: 10 Jan 2011 , 10 Jan 2011

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