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GTF2F2 Gene

protein-coding   GIFtS: 59

GC13P026496
general transcription factor IIF, polypeptide 2, 30kDa
(Previous names: general transcription factor IIF, polypeptide 1 (74kD subunit) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
general transcription factor IIF, polypeptide 2, 30kDa1 2     TFIIF-beta2 3
RAP301 2 3     ATP-dependent helicase GTF2F22 3
BTF41 2     general transcription factor IIF, polypeptide 1 (74kD subunit)1
TFIIF1 2     general transcription factor IIF subunit 22
General transcription factor IIF 30 kDa subunit2 3     TF2F22
Transcription initiation factor RAP302 3     EC 3.6.4.123
Transcription initiation factor IIF subunit beta2 3     

External Ids:    HGNC: 46531   Entrez Gene: 29632   Ensembl: ENSG000001883427   UniProtKB: P139843   

Export aliases for GTF2F2 gene to outside databases

Previous GC identifers: GC13P043694 GC13P039681 GC13P044631 GC13P043492 GC13P044592 GC13P045694


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: T2FB_HUMAN, P13984
Function: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to
the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows
ATP-dependent DNA-helicase activity

Gene Wiki entry for GTF2F2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GTF2F2 gene promoter:
         E2F-3a   E2F-5   E2F-4   E2F-2   E2F-1   E2F   Nkx6-1   Cdc5   RFX1   HOXA9B   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for GTF2F2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q14   Ensembl cytogenetic band:  13q14.12   HGNC cytogenetic band: 13q14

GTF2F2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GTF2F2 gene location

GeneLoc gene densities for chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13P026496:  view genomic region     (about GC identifiers)

Start:
26,496,415 bp from pter
End:
26,659,718 bp from pter
Size:
163,304 bases
Orientation:
plus strand

1 alternative location:
Chr13+ 45,694,650-45,858,237     
RefSeq DNA sequence:
NC_000013.10  NT_024524.14  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: T2FB_HUMAN, P13984 (See protein sequence)
Recommended Name: General transcription factor IIF subunit 2  
Size: 249 amino acids; 28380 Da
Subunit: Heterodimer of an alpha and a beta subunit. Interacts with HTATSF1 and GPBP1 (By similarity)
Subcellular location: Nucleus
PDB structures from and Proteopedia :
1BBY (3D)    1F3U (3D)    2BBY (3D)    
Secondary accessions: A6NNS5 Q5W0H3

Explore the universe of human proteins at neXtProt for GTF2F2: NX_P13984 

Post-translational modifications:

  • Phosphorylated upon DNA damage, probably by ATM or ATR1
  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_004119.1  

    ENSEMBL proteins: 
    ENSP00000340823 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: GTF2F2
    OriGene Protein Over-expression Lysate: GTF2F2
    GenScript Custom Purified and Recombinant Proteins Services for GTF2F2 
    Novus Biologicals Protein for GTF2F2
    Novus Biologicals Lysates for GTF2F2
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins

    4 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634 nucleus IDA18029348
    GO:0005654 nucleoplasm TAS--
    GO:0005674 transcription factor TFIIF complex IEA--
    GO:0015630 microtubule cytoskeleton IDA18029348
    About this table

    GTF2F2 for ontologies           About GeneDecksing



    Antibodies for GTF2F2: 
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for GTF2F2
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    GenScript Custom Superior Antibodies Services for GTF2F2 
    Novus Biologicals Antibody for GTF2F2
    Browse antibodies at Epitomics

    Assays for GTF2F2: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for GTF2F2 
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for GTF2F2 


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    GTF2F2 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR011991 WHTH_trsnscrt_rep_DNA-bd
     IPR003196 TFIIF_beta
     IPR016640 TFIIF-beta_sub
     IPR011039 TFIIF_interaction

    Graphical View of Domain Structure for InterPro Entry P13984

    ProtoNet protein and cluster: P13984

    1 Blocks protein family: IPB003196 Transcription initiation factor IIF

    UniProtKB/Swiss-Prot: T2FB_HUMAN, P13984
    Similarity: Belongs to the TFIIF beta subunit family


    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    UniProtKB/Swiss-Prot: T2FB_HUMAN, P13984
    Function: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to
    the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows
    ATP-dependent DNA-helicase activity
    Catalytic activity: ATP + H(2)O = ADP + phosphate
    Enzyme Number (IUBMB): EC 3.6.4.12 

    Inhib.
    RNA:
        
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for GTF2F2
    Sigma-Aldrich shRNA Panels and shRNA for GTF2F2
    OriGene 29mer shRNA kits in GFP-retroviral vector: GTF2F2
    OriGene shRNA RFP: GTF2F2
    OriGene basic RS shRNA: GTF2F2
    OriGene siRNA: GTF2F2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of GTF2F2 
    miRNA:Sigma-Aldrich microRNA Mimics for GTF2F2
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of GTF2F2 
    Search SABiosciences for Assays for microRNAs that regulate GTF2F2

    Gene
    Editing:
    Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: GTF2F2
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: GTF2F2
    OriGene untagged cDNA clones in CMV expression vector: GTF2F2
    OriGene 3'-UTR clone: GTF2F2 
    Browse MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for GTF2F2 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:
      
    GenScript Custom overexpressing Cell Line Services for GTF2F2 

    Genatlas biochemistry entry for GTF2F2:
    general transcription factor IIF,polypeptide 2(30kDa),increasing the average rate of RNA chain elongation across DNA
    templates

    5/10 Gene Ontology (GO) molecular function terms (GO ID links to tree view) (see all 10):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166 nucleotide binding IEA--
    GO:0003677 DNA binding IEA--
    GO:0003702 RNA polymerase II transcription factor activity ----
    GO:0003824 catalytic activity ----
    GO:0004386 helicase activity IEA--
    About this table

    GTF2F2 for ontologies           About GeneDecksing


    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section


    GTF2F2 for pathways           About GeneDecksing

    1 Millipore Pathway for GTF2F2
        Transcription Ligand-Dependent Transcription of Retinoid-Target genes

    2 Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Pathways for  GTF2F2
        Estrogen Receptor Signaling
    Glucocorticoid Receptor Signaling

    1 Kegg Pathway  (Kegg details for GTF2F2):
        hsa03022 Basal transcription factors

        SABiosciences Custom Pathway-Focused PCR Arrays for GTF2F2 

        Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Molecular Interaction Network for GTF2F2
        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for GTF2F2

    3 Interacting proteins for GTF2F2 (P139841, 2) via UniProtKB, MINT, and/or STRING
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPL27AP467761EBI-1030560,EBI-350581
    TCTEX1D2Q8WW351EBI-1030560,EBI-2692044
    GTF2BQ004032MINT-2982956
    About this table

    5/12 Gene Ontology (GO) biological process terms (GO ID links to tree view) (see all 12):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000398 nuclear mRNA splicing, via spliceosome TAS--
    GO:0006350 transcription TAS--
    GO:0006366 transcription from RNA polymerase II promoter TAS--
    GO:0006367 transcription initiation from RNA polymerase II promoter TAS--
    GO:0006368 RNA elongation from RNA polymerase II promoter TAS--
    About this table

    GTF2F2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    GTF2F2 for compounds           About GeneDecksing

    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GTF2F2
    3 Novoseek chemical compound relationships for GTF2F2 gene
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    phosphodiester 53.5 2 10872452 (1), 8631733 (1)
    alanine 16.2 1 16169872 (1)
    atp 11.9 2 7982911 (1), 8631733 (1)
    About this table



    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section

    Inhib.
    RNA:
         
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for GTF2F2
    Sigma-Aldrich shRNA Panels and shRNA for GTF2F2
    OriGene 29mer shRNA kits in GFP-retroviral vector: GTF2F2
    OriGene shRNA RFP: GTF2F2
    OriGene basic RS shRNA: GTF2F2
    OriGene siRNA: GTF2F2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of GTF2F2 
    miRNA: Sigma-Aldrich microRNA Mimics for GTF2F2
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of GTF2F2 
    Search SABiosciences for Assays for microRNAs that regulate GTF2F2
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: GTF2F2
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: GTF2F2
    OriGene untagged cDNA clones in CMV expression vector: GTF2F2
    OriGene 3'-UTR Clone: GTF2F2 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for GTF2F2 
    Primers: OriGene genome-wide validated SYBR primer pairs: GTF2F2
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for GTF2F2: PPH09605A

    REFSEQ mRNAs for GTF2F2 gene: 

    NM_004128.2  

    Additional cDNA sequence: 

    AK291545.1 BC001771.1 BT019525.1 CR598374.1 CR609785.1 X16901.1 X59745.1 

    7 DOTS entries:

    DT.114042  DT.100796480  DT.100834650  DT.40130785  DT.99997299  DT.120789664  DT.120789671 

    24/152 AceView cDNA sequences (see all 152):

    CF272406 BU184889 CR598374 BG678009 CA444768 CD368832 CB125610 AW004843 
    BQ416647 AA831833 BE906625 CA443379 N73082 BQ422614 BX089414 CB134833 
    BQ001106 BX281310 CB126197 AA831445 CB125216 BU686020 BI755137 BM457007 

    highest scoring ESTs for GTF2F2:

    X16901 AA478656 AA479196 AA831445 AA831833 AA831834 AA868805 AI126584 AI394702 AI400144 

    Unigene Cluster for GTF2F2:

    General transcription factor IIF, polypeptide 2, 30kDa
    Hs.654582  [show with all ESTs]
    Unigene Representative Sequence: NM_004128


    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for GTF2F2

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10a · 10b
    SP1:                    -     -           -     -                                 
    SP2:                    -     -           -     -                                 
    SP3:                          -           -     -                                 
    SP4:                                                                              
    SP5:                                      -     -                                 

    About this scheme

    ECgene alternative splicing isoforms for GTF2F2
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000340473(uc001uzv.2 uc001uzw.2) ENST00000494087 ENST00000461904


    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    GTF2F2 expression in normal and diseased human tissues

    1  / 2  / 3

    3 probe-sets matching GTF2F2 gene

    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    36510_at2, 3 U95-A 1 0.75 1.00 1.00 1.00 X16901 1.00 0.90 0.95 1
    209595_at2, 3 U133-A 1 1.00 1.00 -- -- BC001771 0.80 0.88 0.84 1
    209595_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    About this table

    GTF2F2 for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    GTF2F2 gene expression
    GTF2F2 gene electronic northern expression
    GTF2F2 gene sage expression
    About these images

    CGAP SAGE TAG: CTAGTGAAAC

    SOURCE GeneReport for Unigene cluster: Hs.654582

    Expression variation in blood from EXPOLDB for GTF2F2

    Primers: OriGene genome-wide validated SYBR primer pairs: GTF2F2
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for GTF2F2: PPH09605A
        SABiosciences Custom PCR Arrays for GTF2F2 


    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section

    Orthologs for GTF2F2 gene from 5/14 species (see all 14)
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    GTF2F21   -- general transcription factor IIF, polypeptide 2, 30kDa less 93.57(n)
    97.99(a)
    609164  XM_846373.1  XP_851466.1 
    chimpanzee
    (Pan troglodytes)
    GTF2F21   -- general transcription factor IIF, polypeptide 2, 30kDa less 99.6(n)
    100(a)
    741868  XM_001154142.1  XP_001154142.1 
    cow
    (Bos taurus)
    GTF2F21   -- general transcription factor IIF, polypeptide 2, 30kDa less 92.24(n)
    97.59(a)
    509259  NM_001038064.1  NP_001033153.1 
    rat
    (Rattus norvegicus)
    Gtf2f21   -- general transcription factor IIF, polypeptide 2 90.36(n)
    97.59(a)
    81674  NM_031042.3  NP_112304.2 
    mouse
    (Mus musculus)
    Gtf2f21 , 5 14 (40.29 cM)5
    general transcription factor IIF, polypeptide 21, 5 89.96(n)1
    97.99(a)1
    687051  NM_026816.31  NP_081092.11 
     AI3263155  AI8411865  (see all 12)
    About this table        Species with no ortholog for GTF2F2

    ENSEMBL Gene Tree for GTF2F2 (if available)

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
    Pseudogenes
    2 related pseudogenes



    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/1352 NCBI SNPs in GTF2F2 are shown (see all 1352)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 13 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ----------
    rs7665301,2
    C,F,45752313(-) AACTGT/CTGGCC 1 -- int18Minor allele frequency- C:0.03NA NS EA 544
    rs7665311,2
    C,F,A,45752206(-) tgaagG/Caagac 1 -- int114Minor allele frequency- C:0.15NS EA NA WA 1032
    rs9124141,2
    H45699413(+) AGAAAT/ATTTTT 1 -- int1 trp34Minor allele frequency- A:0.00NS EA 420
    rs9518531,2
    C,F,45810507(-) TATTTC/TCATAA 1 -- int180Minor allele frequency- G:0.03NS EA PA EU CA WA 4152
    rs9570351,2
    C,F,O,A,45800647(-) AAATAG/ATATGT 1 -- int116Minor allele frequency- A:0.17NA NS EA WA 1100
    rs14737411,2
    C,A,45715795(-) ACACAC/TACACA 1 -- int15Minor allele frequency- T:0.23NA WA 128
    rs16109991,2
    F45752475(-) agaag-/AAGAAG
            
    cataa
    1 -- int14Minor allele frequency- AAGAAG:0.26EU NA EA 342
    rs18861921,2
    C,F,H,45707733(+) aaaccG/Atctga 1 -- int111Minor allele frequency- A:0.03NS EA NA WA 432
    rs19648761,2
    --45833941(-) gtggcA/Gggcgc 1 -- int10--------
    rs19807591,2
    C,F,O,A,H,45805760(+) CCACAA/GCTGGT 1 -- int118Minor allele frequency- G:0.26NS EA NA WA 1132
    About this table

    HapMap Linkage Disequilibrium images for GTF2F2 (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for GTF2F2: --

    QIAGEN SeqTarget long-range PCR primers for resequencing GTF2F2 

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    GTF2F2 for disorders           About GeneDecksing

    OMIM: 189969


    Export disorders and mutations for GTF2F2 gene to outside databases

    (Possibly Related Articles in Doctor's Guide)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/115 PubMed articles for GTF2F2 gene, integrated from 7 sources (see all 115):
    (articles sorted by number of sources associating them with GTF2F2)
    1. Tat-SF1 protein associates with RAP30 and human SPT5 proteins. (PubMed id 10454543)1, 2, 7 Kim J.B.... Sharp P.A. (1999)
    2. Global phosphoproteome of HT-29 human colon adenocarcinoma cells. (PubMed id 16083285)1, 2 Kim J.-E.... White F.M. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Structural homology between the Rap30 DNA-binding domain and linker histone H5: implications for preinitiation complex assembly. (PubMed id 9689043)1, 2 Groft C.M.... Werner M.H. (1998)
    5. Genes encoding general initiation factors for RNA polymerase II transcription are dispersed in the human genome. (PubMed id 8162052)1, 3 Heng H.H....Tsui L.C. (1994)
    6. Nucleotide and amino acid sequence of RAP30. (PubMed id 1840667)1, 2 Horikoshi M.... Roeder R.G. (1991)
    7. Structure and associated DNA-helicase activity of a general transcription initiation factor that binds to RNA polymerase II. (PubMed id 2477704)1, 2 Sopta M.... Greenblatt J. (1989)
    8. Interaction with general transcription factor IIF (TFIIF) is required for the suppression of activated transcription by RPB5-mediating protein (RMP). (PubMed id 12737519)1, 7 Wei W....Murakami S. (2003)
    9. Mutational analysis of human RNA polymerase II subunit 5 (RPB5): the residues critical for interactions with TFIIF subunit RAP30 and hepatitis B virus X protein. (PubMed id 16169872)1, 7 Le T.T....Murakami S. (2005)
    10. Distinct domains of hTAFII100 are required for functional interaction with transcription factor TFIIF beta (RAP30) and incorporation into the TFIID complex. (PubMed id 8758937)1, 7 Dubrovskaya V....Tora L. (1996)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 2963 HGNC: 4653 AceView: GTF2F2 Ensembl:ENSG00000188342 euGenes: HUgn2963
    ECgene: GTF2F2 Kegg: 2963 H-InvDB: GTF2F2

    (According to HUGE)
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    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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    (Patent information from GeneIP,
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    Patent Information for GTF2F2 gene:
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