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HOXA3 Gene

protein-coding GIFtS: 47

GC07M027026

homeobox A3
(Previous name: homeo box A3 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbols: HOX1E, HOX1)

		Products

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases & Descriptions
homeobox A3¹ ²		homeobox protein Hox-A3²
HOX1E² ³ ⁵		HOX1²
homeo box A3¹ ²		homeo box 1E²
Homeobox protein Hox-1E² ³		Hox-1.5-like protein²
MGC10155²

External Ids:	HGNC: 5104¹	Entrez Gene: 3200²	Ensembl: ENSG00000105997⁷	UniProtKB: O43365³

Export aliases for HOXA3 gene to outside databases

Previous GC identifers: GC07M026788 GC07M026888 GC07M026919 GC07M027113

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for HOXA3:

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named

A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during

embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription

factor which may regulate gene expression, morphogenesis, and differentiation. Three transcript variants encoding two

different isoforms have been found for this gene. (provided by RefSeq)

UniProtKB/Swiss-Prot: HXA3_HUMAN, O43365

Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells

with specific positional identities on the anterior-posterior axis

Gene Wiki entry for HOXA3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the HOXA3 gene promoter:
         GATA-2   AP-2alphaA   AP-2gamma   HNF-4alpha2   Sp1   FOXO1a   POU3F2   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   HNF-1A
         Other transcription factors

Search SABiosciences Chromatin IP Primers for HOXA3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for HOXA3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p15.2 Ensembl cytogenetic band: 7p15.2 HGNC cytogenetic band: 7p15.2

HOXA3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HOXA3 gene location

GeneLoc gene densities for chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07M027026: view genomic region (about GC identifiers)

Start:	27,026,400 bp from pter
End:	27,047,209 bp from pter
Size:	20,810 bases
Orientation:	minus strand

1 alternative location:

Chr7- 27,145,809-27,192,200

RefSeq DNA sequence:

NC_000007.13 NT_007819.17 NT_079592.2

(According to ¹UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: HXA3_HUMAN, O43365 (See protein sequence)

Recommended Name: Homeobox protein Hox-A3

Size: 443 amino acids; 46369 Da

Subcellular location: Nucleus

Secondary accessions: A4D181

Explore the universe of human proteins at neXtProt for HOXA3: NX_O43365

REFSEQ proteins (2 alternative transcripts):

NP_109377.1 NP_705895.1

ENSEMBL proteins:

ENSP00000401644 ENSP00000379640 ENSP00000430111 ENSP00000324884 ENSP00000430566 ENSP00000429426

ENSP00000379639

Human Recombinant Proteins

	Browse Purified and Recombinant Proteins at Millipore
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	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate: HOXA3
	GenScript Custom Purified and Recombinant Proteins Services for HOXA3
	Novus Biologicals Protein for HOXA3
	Novus Biologicals Lysate for HOXA3
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins

2 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	18029348
GO:0005730	NOT nucleolus	IDA	18029348

About this table

HOXA3 for ontologies About GeneDecksing

Antibodies for HOXA3:

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Assays for HOXA3:

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	GenScript Custom Assay Services for HOXA3
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for HOXA3

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

HOXA3 for domains About GeneDecksing

5/6 InterPro domains/families (see all 6):

IPR001827 Homeobox_Antennapedia_CS

IPR001356 Homeobox

IPR017970 Homeobox_CS

IPR020479 Homeobox_eu

IPR009057 Homeodomain-like

Graphical View of Domain Structure for InterPro Entry O43365

ProtoNet protein and cluster: O43365

2 Blocks protein families:

IPB000047 Lambda and other repressor helix-turn-helix signature

IPB001827 Homeobox protein

UniProtKB/Swiss-Prot: HXA3_HUMAN, O43365

Similarity: Belongs to the Antp homeobox family

Similarity: Contains 1 homeobox DNA-binding domain

(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: HXA3_HUMAN, O43365

Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells

with specific positional identities on the anterior-posterior axis

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Browse Nano Scale siRNA at Sigma-Aldrich Sigma-Aldrich esiRNA and siRNA for HOXA3 Sigma-Aldrich shRNA for HOXA3
		OriGene 29mer shRNA kits in GFP-retroviral vector (see all 3): HOXA3 OriGene shRNA RFP (see all 3): HOXA3 OriGene basic RS shRNA (see all 3): HOXA3 OriGene siRNA (see all 3): HOXA3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of HOXA3

miRNA:		Sigma-Aldrich microRNA Mimics for HOXA3 Browse microRNA target validation systems at Sigma-Aldrich
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of HOXA3
		8/17 SABiosciences Assays for microRNAs that regulate HOXA3 (see all 17):
		hsa-miR-607 hsa-miR-1226 hsa-miR-10b hsa-miR-301a hsa-miR-1274b hsa-miR-519a hsa-miR-375 hsa-miR-23a

Gene
Editing:

Browse CompoZr Knockout ZFN at Sigma-Aldrich

Clones:		Browse Clones for the Expression of Recombinant Proteins Available from Millipore
		Browse iPSC Reprogramming Factors at Sigma-Aldrich
		OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): HOXA3 OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): HOXA3 OriGene untagged cDNA clones in CMV expression vector (see all 3): HOXA3 Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		GenScript Custom cDNA clone Services for HOXA3
		Browse Sino Biological Human cDNA Clones

Cell
Lines:

GenScript Custom overexpressing Cell Line Services for HOXA3

Genatlas biochemistry entry for HOXA3:

homeo box A3(1E),homologous to mouse Hox-1.5,Drosophila Zen1,Zen2

4 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	sequence-specific DNA binding transcription factor activity	IEA	--
GO:0005515	protein binding	IEA	--
GO:0030528	transcription regulator activity	IEA	--
GO:0043565	sequence-specific DNA binding	IEA	--

About this table

HOXA3 for ontologies About GeneDecksing

Animal Models: 13 MGI mutant phenotypes (inferred from 8 alleles) (MGI details for Hoxa3):

cardiovascular system	craniofacial	digestive/alimentary	embryogenesis	endocrine/exocrine gland
growth/size	hematopoietic system	immune system	lethality-prenatal/perinatal	muscle
nervous system	respiratory system	skeleton

HOXA3 for phenotypes About GeneDecksing

(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section

SABiosciences Pathway-Focused PCR Array including HOXA3: PAHS-3401A

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for HOXA3

5/16 Gene Ontology (GO) biological process terms (GO ID links to tree view) (see all 16):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001525	angiogenesis	IEP	17972163
GO:0001974	blood vessel remodeling	IEA	--
GO:0006355	regulation of transcription, DNA-dependent	IEA	--
GO:0007275	multicellular organismal development	IEA	--
GO:0008284	positive regulation of cell proliferation	IEA	--

About this table

HOXA3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

HOXA3 for compounds About GeneDecksing

Browse Small Molecules at Sigma-Aldrich

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for HOXA3
1 Novoseek chemical compound relationship for HOXA3 gene

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
retinoic acid	41	5	12756180 (2), 9894676 (2)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Browse Nano Scale siRNA at Sigma-Aldrich Sigma-Aldrich esiRNA and siRNA for HOXA3 Sigma-Aldrich shRNA for HOXA3
		OriGene 29mer shRNA kits in GFP-retroviral vector (see all 3): HOXA3 OriGene shRNA RFP (see all 3): HOXA3 OriGene basic RS shRNA (see all 3): HOXA3 OriGene siRNA (see all 3): HOXA3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of HOXA3

miRNA:		Sigma-Aldrich microRNA Mimics for HOXA3 Browse microRNA target validation systems at Sigma-Aldrich
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of HOXA3
		8/17 SABiosciences Assays for microRNAs that regulate HOXA3 (see all 17):
		hsa-miR-607 hsa-miR-1226 hsa-miR-10b hsa-miR-301a hsa-miR-1274b hsa-miR-519a hsa-miR-375 hsa-miR-23a

Clones:		Browse FLAG tag genes at Sigma-Aldrich
		OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): HOXA3 OriGene Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): HOXA3 OriGene untagged cDNA clones in CMV expression vector (see all 3): HOXA3 Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		GenScript Custom cDNA clone Services for HOXA3

Primers:		OriGene genome-wide validated SYBR primer pairs: HOXA3 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay for HOXA3: PPH14990A

REFSEQ mRNAs for HOXA3 gene (2 alternative transcripts):

NM_030661.4 NM_153631.2

Additional cDNA sequence:

AK056567.1 AK094200.1 BC015180.1 DQ655986.2

10 DOTS entries:

DT.40232900 DT.87046691 DT.121115437 DT.121115457 DT.40253843 DT.121115445 DT.121115459 DT.97777553

DT.100884355 DT.121115444

24/81 AceView cDNA sequences (see all 81):

BF435327 NM_153632 NM_030661 AW849525 AW166311 BM824037 AA534436 AA947856

AW015589 AI831660 NM_153631 BF593069 AI627633 BG413439 AW080161 BX101261

BC015180 M74297 AI206422 BF939880 AK094200 AA580334 BM972058 AI768663

highest scoring ESTs for HOXA3:

AI767994 AI686316 AK056567 AV753908 AW137243 AW137982 AW193522 AW849525 AW883901 BC015180

Unigene Cluster for HOXA3:

Homeobox A3

Hs.659337 [show with all ESTs]

Unigene Representative Sequence: NM_153631

GeneLoc Exon Structure

9 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000454717(uc003syk.2) ENST00000396352(uc011jzk.1 uc011jzl.1)

ENST00000518451 ENST00000521779 ENST00000521401 ENST00000317201 ENST00000522456

ENST00000522788 ENST00000396350

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

HOXA3 expression in normal and diseased human tissues

¹ / ² / ³

5 probe-sets matching HOXA3 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
80208_at²^{, 3}	U95-E	1	0.94	1.00	1.00	1.00	AI686316	0.60	0.62	0.61	1
208604_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_030661	0.40	0.50	0.45	1
235521_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AW137982	0.40	0.50	0.45	1
208604_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
235521_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

HOXA3 for expression About GeneDecksing

Data from Genenote (Publications) and GNF BioGPS
About these images

HOXA3 gene electronic northern expression

About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.659337

Primers:		OriGene genome-wide validated SYBR primer pairs: HOXA3 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay for HOXA3: PPH14990A

SABiosciences Expression via Pathway-Focused PCR Array including HOXA3: PAHS-3401A

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for HOXA3 gene from 5/7 species (see all 7)

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	HOXA3¹	--	homeobox A3	91.61(n) 95.92(a)	482368 XM_859451.1 XP_864544.1
chimpanzee (Pan troglodytes)	HOXA3¹	--	homeobox A3	99.62(n) 99.1(a)	472323 XM_527698.2 XP_527698.1
cow (Bos taurus)	HOXA3¹	--	homeobox A3	88.84(n) 93.89(a)	509991 NM_001076825.1 NP_001070293.1
mouse (Mus musculus)	Hoxa3^{1 , 5}	6 (25.40 cM)⁵	homeobox A3⁵ homeo box A3¹	88.84(n)¹ 93.89(a)¹	15400¹ NM_010452.2¹ NP_034582.1¹ AI046796⁵ AK051552⁵ (see all 12)
chicken (Gallus gallus)	HOXA3¹	--	homeobox A3	76.35(n) 81.6(a)	395231 NM_204548.1 NP_989879.1

About this table Species with no ortholog for HOXA3

ENSEMBL Gene Tree for HOXA3 (if available)

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for HOXA3 gene

GSX1² HOXB1² HOXB3² GSX2² HOXB4² HOXD4² HOXA4² HOXC4²

HOXD3²

HOXA3 for paralogs About GeneDecksing

(SNPs according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

SNP ID	Valid	Chr 7 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample
Genomic Data				Transcription Related Data				Allele Frequencies
			--	--	--		--	--
rs739734^1,2	C,F,A,	27159405(+)	`GTTGTC/TCAAAT`	1	--	ng5¹		13	NA EA NS WA	2642
rs1978133^1,2	C,F,H,	27146807(+)	`TATTGC/TATCGT`	2	--	ut3¹		12	MN NS EA NA WA	856
rs1989935^1,2	C,F,A,H,	27146138(+)	`TCCCCA/GGAGGA`	2	--	ut3¹ ese³		9	MN NS EA NA WA	660
rs2285721^1,2	C,H,	27155353(+)	`AGATCT/CGGGGC`	1	--	int¹		2	NA	74
rs2285722^1,2	C,F,	27155426(+)	`TCAGCG/AGGCAG`	1	--	int¹		2	EA	1560
rs2285723^1,2	C,F,	27156472(+)	`AACACT/CTGGTT`	1	--	int¹		6	EA NS	2062
rs2428433^1,2	C,F,A,	27145517(+)	`TTCTGT/CCTCTG`	1	--	ng3¹		8	NS EA NA WA	798
rs2428434^1,2	C,F,A,	27145735(+)	`CCTCTT/ACTAGC`	1	--	ng3¹		7	NS EA NA WA	644
rs2465276^1,2	C,F,	27145717(+)	`TTACTG/ATGCCT`	1	--	ng3¹		8	NS EA NA WA	790
rs3173606^1,2	C,F	27147065(-)	`GCTCTC/TTGTGC`	2	--	ut3¹ ese³		6	MN NS EA	736

About this table

HapMap Linkage Disequilibrium images for HOXA3 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for HOXA3: --

QIAGEN SeqTarget long-range PCR primers for resequencing HOXA3

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section

HOXA3 for disorders About GeneDecksing

OMIM: 142954

Human Genome Epidemiology (HuGE) Navigator: HOXA3 (1 document)

Export disorders and mutations for HOXA3 gene to outside databases

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶UniProtKB/TrEMBL, and/or ⁷Novoseek)
About This Section

10/31 PubMed articles for HOXA3 gene, integrated from 7 sources (see all 31):
(articles sorted by number of sources associating them with HOXA3)

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)^{1, 2} Scherer S.W.... Tsui L.-C. (2003)
The DNA sequence of human chromosome 7. (PubMed id 12853948)^{1, 2} Hillier L.W.... Wilson R.K. (2003)
Vertebrate homeobox gene nomenclature. (PubMed id 1358459)^{1, 3} Scott M.P. (1992)
Nomenclature for human homeobox genes. (PubMed id 1973146)^{1, 3} McAlpine P.J. and Shows T.B. (1990)
Hox group 3 paralogs regulate the development and migration of the thymus, thyroid, and parathyroid glands. (PubMed id 9520319)^{1, 7} Manley N.R. and Capecchi M.R. (1998)
Retinoic acid-induced thymic abnormalities in the mouse are associated with altered pharyngeal morphology, thymocyte maturation defects, and altered expression of Hoxa3 and Pax1. (PubMed id 9894676)^{1, 7} Mulder G.B....Maggio-Price L. (1998)
Krox20 and kreisler co-operate in the transcriptional control of segmental expression of Hoxb3 in the developing hindbrain. (PubMed id 11823429)^{1, 7} Manzanares M....Charnay P. (2002)
An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)¹ Ravasi T....Hayashizaki Y. (2010 Mar 5)
HOX gene analysis of endothelial cell differentiation in human bone marrow-derived mesenchymal stem cells. (PubMed id 17972163)¹ Chung N....Rha H.K. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 3200	HGNC: 5104	AceView: HOXA4andHOXA3	Ensembl:ENSG00000105997	euGenes: HUgn3200
ECgene: HOXA3	H-InvDB: HOXA3

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Intellectual Property for HOXA3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from XenneX, Inc.)

About This Section

Patent Information for HOXA3 gene:
Search GeneIP for patents involving HOXA3

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
About This Section

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
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	Predesigned and custom siRNAs for HOXA3		Antibodies for HOXA3
	Super-pooled esiRNAs for HOXA3		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for HOXA3		microRNA Mimics for HOXA3
	"Your Favorite Gene" Pathways and Molecular Interaction Networks		Browse Nano Scale siRNA at Sigma-Aldrich
	Browse iPSC Reprogramming Factors at Sigma-Aldrich		Browse small molecules at Sigma-Aldrich
	Browse FLAG tag genes at Sigma-Aldrich		Browse ELISAs at Sigma-Aldrich
	Browse microRNA Target Validation Systems at Sigma-Aldrich		Browse CompoZr Knockout ZFN at Sigma-Aldrich
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	ELISAs		Flow Cytometry Kits
	Primer Pairs		Kinase Activity Assays/Reagents
	ELISpot Kits/Development Modules		TFB/Immunoprecipitation Assays
	Apoptosis Detection Kits/Reagents		Protease Activity Assays/Reagents
	DNA Damage/Repair Kits/Reagents		Multiplex/Array Assay Kits/Reagents
	Cell Selection/Detection Kits/Reagents		ELISA/Assay Development Kits/Reagents
	Phosphatase Activity Assays/Reagents		Recombinant/Natural Proteins

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Lysates
	Western blot validated antibodies
	shRNA in GFP-retroviral vector
	siRNA
	Custom Immunoassay Development
	Fluorogenic Cell Assay Kits
	miRNA Primers for qPCR Assays
	3' UTR Clones for miRNA Target Studies
	miRNA Expression Plasmids

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of HOXA3
	SeqTarget long-range PCR primers for resequencing HOXA3
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for HOXA3
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of HOXA3

	GenScript Custom Purified and Recombinant Proteins Services for HOXA3		GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for HOXA3
	GenScript Custom Assay Services for HOXA3		GenScript Custom Superior Antibodies Services for HOXA3
	GenScript Custom overexpressing Cell Line Services for HOXA3		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in HOXA3 promoter
	Search Chromatin IP Primers for HOXA3
	RT² qPCR Primer Assay for HOXA3
	Search GNC Networks for HOXA3
	Assays for microRNAs that regulate HOXA3
	SABiosciences PCR Arrays including HOXA3

Search Tocris compounds for HOXA3

	Browse Sino Biological Proteins and Antibodies
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	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	Antibodies for HOXA3
	Proteins for HOXA3
	Lysates for HOXA3

Browse antibodies at Epitomics

Browse ProSpec Recombinant Proteins

ELISAs and CLIAs for HOXA3

GeneCards Homepage - Last full update: 30 Dec 2010 - Incremental updates: 10 Jan 2011 , 10 Jan 2011

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The GeneCards human gene database gene index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

HOXA3 gene at Home site.

hostname: www-ab3 db genecards_305 index build: 81e solr: 1.4

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HOXA3 Gene

protein-coding GIFtS: 47

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Export list of displayed genes

HOXA3 Gene

protein-coding GIFtS: 47

Aliases & Descriptionsfor HOXA3 gene

Summariesfor HOXA3 gene

Genomic Viewsfor HOXA3 gene

Proteinsfor HOXA3 gene

Protein Domains/Familiesfor HOXA3 gene

Gene Functionfor HOXA3 gene

Pathways & Interactionsfor HOXA3 gene

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Transcriptsfor HOXA3 gene

Expression for HOXA3 gene

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External Searches for HOXA3 gene

Genome Databases showing HOXA3 gene

Other Databases showing HOXA3 gene

Specialized Databases showing HOXA3 gene

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Aliases &
Descriptions
for HOXA3 gene

Summaries
for HOXA3 gene

Genomic Views
for HOXA3 gene

Proteins
for HOXA3 gene

Protein Domains/
Families
for HOXA3 gene

Gene Function
for HOXA3 gene

Pathways & Interactions
for HOXA3 gene

Drugs & Compounds
for HOXA3 gene

Transcripts
for HOXA3 gene

Expression
for HOXA3 gene

Orthologs
for HOXA3 gene

Paralogs
for HOXA3 gene

Genomic Variants
for HOXA3 gene

Disorders & Mutations
for HOXA3 gene

Medical News
for HOXA3 gene

Publications
for HOXA3 gene

Intellectual Property
for HOXA3 gene

Products
for HOXA3 gene