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HOXC10 Gene

protein-coding   GIFtS: 49

GC12P051416
homeobox C10
(Previous name: homeo box C10 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: HOX3I)
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
homeobox C101 2     MGC52592
homeo box C101 2     homeobox protein Hox-C102
Homeobox protein Hox-3I2 3     homeoprotein C102
HOX3I2 3     

External Ids:    HGNC: 51221   Entrez Gene: 32262   Ensembl: ENSG000001808187   UniProtKB: Q9NYD63   

Export aliases for HOXC10 gene to outside databases

Previous GC identifers: GC12M054414 GC12P054491 GC12P054095 GC12P052665 GC12P054378


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for HOXC10:
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription
factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar
homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11
genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The
protein level is controlled during cell differentiation and proliferation, which may indicate this protein has a role
in origin activation. (provided by RefSeq)

UniProtKB/Swiss-Prot: HXC10_HUMAN, Q9NYD6
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells
with specific positional identities on the anterior-posterior axis

Gene Wiki entry for HOXC10

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HOXC10 gene promoter:
         FOXC1   C/EBPalpha   CHOP-10   Arnt   AhR   FAC1   FOXO1a   E47   RP58   NRSF form 1   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for HOXC10

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for HOXC10 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.3   Ensembl cytogenetic band:  12q13.13   HGNC cytogenetic band: 12q13.13

HOXC10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HOXC10 gene location

GeneLoc gene densities for chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P051416:  view genomic region     (about GC identifiers)

Start:
51,416,659 bp from pter
End:
51,421,773 bp from pter
Size:
5,115 bases
Orientation:
plus strand

1 alternative location:
Chr12+ 54,378,849-54,384,063     
RefSeq DNA sequence:
NC_000012.11  NT_029419.12  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: HXC10_HUMAN, Q9NYD6 (See protein sequence)
Recommended Name: Homeobox protein Hox-C10  
Size: 342 amino acids; 38073 Da
Subcellular location: Nucleus
Secondary accessions: O15219 O15220 Q9BVD5

Explore the universe of human proteins at neXtProt for HOXC10: NX_Q9NYD6 

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_059105.2  

    ENSEMBL proteins: 
    ENSP00000421946 ENSP00000307321 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
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    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: HOXC10
    GenScript Custom Purified and Recombinant Proteins Services for HOXC10 
    Novus Biologicals Protein for HOXC10
    Novus Biologicals Lysate for HOXC10
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins

    2 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634 nucleus IEA--
    GO:0019907colocalizes with cyclin-dependent protein kinase activating kinase holoenzyme complex IDA11445587
    About this table

    HOXC10 for ontologies           About GeneDecksing



    Antibodies for HOXC10: 
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    GenScript Custom Assay Services for HOXC10 
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for HOXC10 


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    HOXC10 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR001356 Homeobox
     IPR017970 Homeobox_CS
     IPR020479 Homeobox_eu
     IPR009057 Homeodomain-like
     IPR012287 Homeodomain-rel

    Graphical View of Domain Structure for InterPro Entry Q9NYD6

    ProtoNet protein and cluster: Q9NYD6

    UniProtKB/Swiss-Prot: HXC10_HUMAN, Q9NYD6
    Similarity: Belongs to the Abd-B homeobox family
    Similarity: Contains 1 homeobox DNA-binding domain


    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    UniProtKB/Swiss-Prot: HXC10_HUMAN, Q9NYD6
    Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells
    with specific positional identities on the anterior-posterior axis

    Inhib.
    RNA:
        
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for HOXC10
    Sigma-Aldrich shRNA for HOXC10
    OriGene 29mer shRNA kits in GFP-retroviral vector: HOXC10
    OriGene shRNA RFP: HOXC10
    OriGene basic RS shRNA: HOXC10
    OriGene siRNA: HOXC10
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of HOXC10 
    miRNA:Sigma-Aldrich microRNA Mimics for HOXC10
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of HOXC10 
    3 SABiosciences Assays for microRNAs that regulate HOXC10:
    hsa-miR-136 hsa-miR-129-5p hsa-miR-510

    Gene
    Editing:
    Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: HOXC10
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: HOXC10
    OriGene untagged cDNA clones in CMV expression vector: HOXC10
    OriGene 3'-UTR clone: HOXC10 
    Browse MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for HOXC10 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:
      
    GenScript Custom overexpressing Cell Line Services for HOXC10 

    Genatlas biochemistry entry for HOXC10:
    homeo box C10(3I),homologous to mouse Hox-3.6,involved in mouse posterior limb patterning,expressed in posterior limb

    4 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003700 sequence-specific DNA binding transcription factor activity IEA--
    GO:0003702 RNA polymerase II transcription factor activity TAS10835276
    GO:0005515 protein binding IEA--
    GO:0043565 sequence-specific DNA binding IEA--
    About this table

    HOXC10 for ontologies           About GeneDecksing

    Animal Models: 7 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Hoxc10):

    behavior/neurologicalgrowth/sizelimbs/digits/tailmusclenervous system
    renal/urinary systemskeleton

    HOXC10 for phenotypes           About GeneDecksing


    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section

        SABiosciences Pathway-Focused PCR Array including HOXC10: PAHS-083A 

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HOXC10

    5 Interacting proteins for HOXC10 (ENSP000003073213) via UniProtKB, MINT, and/or STRING
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ERCC2ENSP000002214813STRING: ENSP00000221481
    HSPD1ENSP000003400193STRING: ENSP00000340019
    KDM5AENSP000003722653STRING: ENSP00000372265
    PUF60ENSP000003220163STRING: ENSP00000322016
    --ENSP000003694473STRING: ENSP00000369447
    About this table

    5/9 Gene Ontology (GO) biological process terms (GO ID links to tree view) (see all 9):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001501 skeletal system development IEA--
    GO:0006355 regulation of transcription, DNA-dependent IEA--
    GO:0007275 multicellular organismal development IEA--
    GO:0008284 positive regulation of cell proliferation TAS10835276
    GO:0009952 anterior/posterior pattern formation IEA--
    About this table

    HOXC10 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section
    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HOXC10


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section

    Inhib.
    RNA:
         
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for HOXC10
    Sigma-Aldrich shRNA for HOXC10
    OriGene 29mer shRNA kits in GFP-retroviral vector: HOXC10
    OriGene shRNA RFP: HOXC10
    OriGene basic RS shRNA: HOXC10
    OriGene siRNA: HOXC10
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of HOXC10 
    miRNA: Sigma-Aldrich microRNA Mimics for HOXC10
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of HOXC10 
    3 SABiosciences Assays for microRNAs that regulate HOXC10:
    hsa-miR-136 hsa-miR-129-5p hsa-miR-510
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: HOXC10
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: HOXC10
    OriGene untagged cDNA clones in CMV expression vector: HOXC10
    OriGene 3'-UTR Clone: HOXC10 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for HOXC10 
    Primers: OriGene genome-wide validated SYBR primer pairs: HOXC10
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for HOXC10: PPH09247A

    REFSEQ mRNAs for HOXC10 gene: 

    NM_017409.3  

    Additional cDNA sequence: 

    AF255675.1 AK313759.1 BC001293.1 BT009921.1 CR600861.1 CR622939.1 X99685.1 

    4 DOTS entries:

    DT.448032  DT.91692757  DT.95307803  DT.91909674 

    24/228 AceView cDNA sequences (see all 228):

    AI174335 BF434131 BE396026 BE464190 BF057562 BQ890449 NM_014620 AL558161 
    AI631879 AI200419 AI159844 BM127627 NM_018953 AA629181 AI215607 BF434950 
    BX280842 AW299598 AA827833 T28272 BF591158 AW000987 BC074845 AA158947 

    highest scoring ESTs for HOXC10:

    AI670876 AW024474 BE545448 BE813426 AA112396 AA190344 AA190345 AA307551 AA411006 AA502954 

    Unigene Cluster for HOXC10:

    Homeobox C10
    Hs.44276  [show with all ESTs]
    Unigene Representative Sequence: NM_017409


    GeneLoc Exon Structure

    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000515593 ENST00000303460(uc001sen.2) ENST00000511575 ENST00000514415
    ENST00000513413

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    HOXC10 expression in normal and diseased human tissues

    1  / 2  / 3

    4 probe-sets matching HOXC10 gene

    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    57830_s_at2, 3 U95-C 1 0.94 1.00 0.98 1.16 AW024474 1.00 0.85 0.93 1
    52117_at2, 3 U95-B 1 0.88 1.00 0.98 0.85 AI670876 1.00 0.85 0.93 1
    218959_at2, 3 U133-A 1 0.82 1.00 -- -- NM_017409 0.60 0.75 0.68 1
    218959_at2 U133Plus2 1 0.82 1.00 -- -- -- -- -- -- --
    About this table

    HOXC10 for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    HOXC10 gene expression
    HOXC10 gene electronic northern expression
    HOXC10 gene sage expression
    About these images

    CGAP SAGE TAG: TAGCTTCCTT

    SOURCE GeneReport for Unigene cluster: Hs.44276
    Primers: OriGene genome-wide validated SYBR primer pairs: HOXC10
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for HOXC10: PPH09247A
        SABiosciences Expression via Pathway-Focused PCR Array including HOXC10: PAHS-083A 


    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section

    Orthologs for HOXC10 gene from 5/6 species (see all 6)
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    chimpanzee
    (Pan troglodytes)
    HOXC101   -- homeobox C10 99.71(n)
    99.42(a)
    451947  XM_509105.2  XP_509105.2 
    rat
    (Rattus norvegicus)
    Hoxc101   -- homeo box C10 95.32(n)
    97.37(a)
    315338  XM_235698.4  XP_235698.2 
    mouse
    (Mus musculus)
    Hoxc101 , 5 15 (58.03 cM)5
    homeobox C105
    homeo box C101
    95.41(n)1
    97.76(a)1
    2094481  NM_010462.31  NP_034592.11 
     AI5066215  AK0331865  (see all 10)
    chicken
    (Gallus gallus)
    HOXC101   -- homeobox C10 68.79(n)
    67.02(a)
    770471  XM_001233805.1  XP_001233806.1 
    African clawed frog
    (Xenopus laevis)
    Xl.218642   -- Xenopus laevis Hoxc10 mRNA, complete cds 77.41(n)  AY167741.1 
    About this table        Species with no ortholog for HOXC10

    ENSEMBL Gene Tree for HOXC10 (if available)

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
    Paralogs for HOXC10 gene
    HOXA92  HOXA112  HOXB92  HOXC92  HOXD112  HOXD92  HOXC112  HOXD102  
    HOXA102  

    HOXC10 for paralogs           About GeneDecksing



    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/59 NCBI SNPs in HOXC10 are shown (see all 59)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 12 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ----------
    rs10476601,2
    C,F54383743(+) ACCCTC/TTCCAT 1 -- ut31 ese35Minor allele frequency- T:0.00MN NS EA 594
    rs37823971,2
    C,F,A,H,54380016(+) CGGCCG/ATGGGT 1 -- int16Minor allele frequency- A:0.42NA WA 12
    rs38328291,2
    C54383935(+) CCCCC-/CCAAATA 1 -- ut311Minor allele frequency- CC:0.00NA 2
    rs42378101,2
    C,F,A,H,54383500(-) GAGGGT/CTTGAC 1 -- ut31 ese38Minor allele frequency- C:0.10NS NA WA 118
    rs45643841,2
    C,F,A,H,54379670(-) GGGCTA/C/GGGGGT 3 P ref1 syn1 ese32NA 8
    rs73022431,2
    C,F,54384204(+) GTGAGA/GGACCA 1 -- ng319Minor allele frequency- G:0.11NS EA NA WA 608
    rs73027031,2
    C,F,A,54384387(+) AGCAAG/ACTGCA 1 -- ng3110Minor allele frequency- A:0.28NS EA NA WA 624
    rs73153111,2
    C54380000(+) GGTGTC/TGGCCC 1 -- int10--------
    rs79587121,2
    C,H,54378343(+) TTTGGG/TATTCC 1 -- ng516Minor allele frequency- T:0.00NA WA 12
    rs105986011,2
    --54383925(+) GAATG-/CCCCCCC 1 -- ut310--------
    About this table

    HapMap Linkage Disequilibrium images for HOXC10 (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for HOXC10
         1 CNV: 3890

    QIAGEN SeqTarget long-range PCR primers for resequencing HOXC10 

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    HOXC10 for disorders           About GeneDecksing

    OMIM: 605560


    Export disorders and mutations for HOXC10 gene to outside databases

    (Possibly Related Articles in Doctor's Guide)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/16 PubMed articles for HOXC10 gene, integrated from 7 sources (see all 16):
    (articles sorted by number of sources associating them with HOXC10)
    1. Selection of homeotic proteins for binding to a human DNA replication origin. (PubMed id 10835276)1, 2, 7 de Stanchina E.... Biamonti G. (2000)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Distinct patterns of all-trans retinoic acid dependent expression of HOXB and HOXC homeogenes in human embryonal and small-cell lung carcinoma cell lines. (PubMed id 9357979)1, 2 Flagiello D.... Malfoy B. (1997)
    4. Vertebrate homeobox gene nomenclature. (PubMed id 1358459)1, 3 Scott M.P. (1992)
    5. Gene expression analysis of preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasion. (PubMed id 17974957)1, 7 Zhai Y....Cho K.R. (2007)
    6. HOXC10 as a potential marker for discriminating betwe en amnion- and decidua-derived mesenchymal stem cells. (PubMed id 19522674)1 Hwang J.H....Lee J.K. (2009)
    7. Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)2 Daub H.... Mann M. (2008)
    8. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
    9. Dynamic profiling of the post-translational modificat ions and interaction partners of epidermal growth factor receptor signaling aft er stimulation by epidermal growth factor using Extended Range Proteomic Analys is (ERPA). (PubMed id 16799092)1 Wu S.L....Karger B.L. (2006)
    10. Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression. (PubMed id 12853486)1 Gabellini D....Peverali F.A. (2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 3226 HGNC: 5122 AceView: HOXC6 Ensembl:ENSG00000180818 euGenes: HUgn3226
    ECgene: HOXC10 H-InvDB: HOXC10

    (According to HUGE)
    About This Section
      --

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
      --

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
    About This Section
    Patent Information for HOXC10 gene:
    Search GeneIP for patents involving HOXC10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
    Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
    About This Section

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services

     Predesigned and custom siRNAs for HOXC10 Antibodies for HOXC10
     Super-pooled esiRNAs for HOXC10 Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for HOXC10 microRNA Mimics for HOXC10
     "Your Favorite Gene" Pathways and Molecular Interaction Networks Browse Nano Scale siRNA at Sigma-Aldrich
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     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for HOXC10
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     ELISAs and CLIAs for HOXC10
           

    GeneCards Homepage - Last full update: 30 Dec 2010 - Incremental updates: 10 Jan 2011 , 10 Jan 2011

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