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HSH2D Gene

protein-coding GIFtS: 48

GC19P015815

hematopoietic SH2 domain containing
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

		Products

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases & Descriptions
hematopoietic SH2 domain containing¹ ²		Hematopoietic SH2 protein² ³
ALX¹ ² ³		Adaptor in lymphocytes of unknown function X² ³
HSH2¹ ²		hematopoietic SH2 domain-containing protein²
FLJ14886¹ ²

External Ids:	HGNC: 24920¹	Entrez Gene: 84941²	Ensembl: ENSG00000196684⁷	UniProtKB: Q96JZ2³

Export aliases for HSH2D gene to outside databases

Previous GC identifers: GC19P016106 GC19P016107 GC19P015938 GC19P016244

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for HSH2D:

T-cell activation requires 2 signals: recognition of antigen by the T-cell receptor (see TCR; MIM 186880) and a

costimulatory signal provided primarily by CD28 (MIM 186760) in naive T cells. HSH2 is a target of both of these

signaling pathways (Greene et al., 2003 (PubMed 12960172)).(supplied by OMIM)

UniProtKB/Swiss-Prot: HSH2D_HUMAN, Q96JZ2

Function: May be a modulator of the apoptotic response through its ability to affect mitochondrial stability (By

similarity). Adapter protein involved in tyrosine kinase and CD28 signaling. Seems to affect CD28-mediated activation

of the RE/AP element of the interleukin-2 promoter

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the HSH2D gene promoter:
         NF-kappaB1   AP-1   c-Fos   c-Jun   NF-kappaB   Sp1   GR-alpha   ARP-1   TGIF   MIF-1
         Other transcription factors

Search SABiosciences Chromatin IP Primers for HSH2D

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.12 Ensembl cytogenetic band: 19p13.12 HGNC cytogenetic band: 19p13.12

HSH2D Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HSH2D gene location

GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19P015815: view genomic region (about GC identifiers)

Start:	15,815,784 bp from pter
End:	15,840,224 bp from pter
Size:	24,441 bases
Orientation:	plus strand

1 alternative location:

Chr19+ 16,254,396-16,269,344

RefSeq DNA sequence:

NC_000019.9 NT_011295.11

(According to ¹UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: HSH2D_HUMAN, Q96JZ2 (See protein sequence)

Recommended Name: Hematopoietic SH2 domain-containing protein

Size: 352 amino acids; 39002 Da

Subunit: Interacts with FES and TNK2

Subcellular location: Cytoplasm. Nucleus

PDB structures from and Proteopedia :

2CS0 (3D)

Secondary accessions: B5ME72 Q6ZNG7

Alternative splicing: 2 isoforms: Q96JZ2-1 Q96JZ2-2

Explore the universe of human proteins at neXtProt for HSH2D: NX_Q96JZ2

Post-translational modifications:

May be phosphorylated by FES and ACK1¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_116244.1

ENSEMBL proteins:

ENSP00000380528 ENSP00000253680

Human Recombinant Proteins

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2 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--
GO:0005737	cytoplasm	IEA	--

About this table

HSH2D for ontologies About GeneDecksing

Antibodies for HSH2D:

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	Uscn ELISAs and CLIAs for HSH2D

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

HSH2D for domains About GeneDecksing

1 InterPro domain/family:

IPR000980 SH2

Graphical View of Domain Structure for InterPro Entry Q96JZ2

ProtoNet protein and cluster: Q96JZ2

1 Blocks protein family: IPB000980 SH2 domain signature

UniProtKB/Swiss-Prot: HSH2D_HUMAN, Q96JZ2

Similarity: Contains 1 SH2 domain

(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: HSH2D_HUMAN, Q96JZ2

Function: May be a modulator of the apoptotic response through its ability to affect mitochondrial stability (By

similarity). Adapter protein involved in tyrosine kinase and CD28 signaling. Seems to affect CD28-mediated activation

of the RE/AP element of the interleukin-2 promoter

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of HSH2D
		Search SABiosciences for Assays for microRNAs that regulate HSH2D

Gene
Editing:

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		OriGene GFP tagged cDNA clones in CMV expression vector: HSH2D OriGene Myc/DDK tagged cDNA clones in CMV expression vector: HSH2D OriGene untagged cDNA clones in CMV expression vector (see all 2): HSH2D OriGene 3'-UTR clone: HSH2D Browse MicroRNA Expression Plasmids
		GenScript cDNA clone with any tag delivered in your preferred vector: HSH2D
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Cell
Lines:

GenScript Custom overexpressing Cell Line Services for HSH2D

2 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005070	SH3/SH2 adaptor activity	IEA	--
GO:0005515	protein binding	IEA	--

About this table

HSH2D for ontologies About GeneDecksing

Animal Models: 2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Hsh2d):

hematopoietic system

immune system

HSH2D for phenotypes About GeneDecksing

(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section

SABiosciences Custom Pathway-Focused PCR Arrays for HSH2D

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for HSH2D

1 Gene Ontology (GO) biological process term (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0042110	T cell activation	IEA	--

About this table

HSH2D for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse Small Molecules at Sigma-Aldrich

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for HSH2D

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
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		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of HSH2D

miRNA:		Sigma-Aldrich microRNA Mimics for HSH2D Browse microRNA target validation systems at Sigma-Aldrich
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of HSH2D
		Search SABiosciences for Assays for microRNAs that regulate HSH2D

Clones:		Browse FLAG tag genes at Sigma-Aldrich
		OriGene GFP tagged cDNA clones in CMV expression vector: HSH2D OriGene Myc/DDK tagged cDNA clones in CMV expression vector: HSH2D OriGene untagged cDNA clones in CMV expression vector (see all 2): HSH2D OriGene 3'-UTR Clone: HSH2D Browse OriGene MicroRNA Expression Plasmids
		GenScript cDNA clone with any tag delivered in your preferred vector: HSH2D

Primers:		OriGene genome-wide validated SYBR primer pairs: HSH2D Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay for HSH2D: PPH23413A

REFSEQ mRNAs for HSH2D gene:

NM_032855.2

Additional cDNA sequence:

AK027792.1 AK131222.1 AK298682.1 AK300027.1 AK307563.1 AY319652.1 BC016826.1 BC025237.2

9 DOTS entries:

DT.206653 DT.40120606 DT.100756604 DT.75134736 DT.86852573 DT.121496134 DT.436661 DT.121496119

DT.75172695

24/536 AceView cDNA sequences (see all 536):

BC025237 CR542274 BM824094 CR594350 CR597154 BQ233493 BQ674769 BQ422922

BP365166 AI126505 BU543352 BP352452 BQ083814 BQ070820 BM762334 BM464622

AF498943 BM978303 BM475359 BX385694 BU168489 AK025165 BM923211 CA455095

highest scoring ESTs for HSH2D:

T54146 AA280878 AA766987 AI940118 AK027792 AK131222 AV735509 AW958453 BC016826 BC025237

Unigene Cluster for HSH2D:

Hematopoietic SH2 domain containing

Hs.631617 [show with all ESTs]

Unigene Representative Sequence: AK131222

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for HSH2D (see all 6)

ExUns:	1a	·	1b	^	2a	·	2b	^	3	^	4a	·	4b	·	4c	^	5a	·	5b	^	6	^	7a	·	7b
SP1:
SP2:									-				-		-		-
SP3:									-				-		-
SP4:									-				-		-		-
SP5:									-

About this scheme

ECgene alternative splicing isoforms for HSH2D
2 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000397372(uc002ndr.2) ENST00000253680(uc002ndp.3 uc010ead.2)

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

HSH2D expression in normal and diseased human tissues

¹ / ² / ³

3 probe-sets matching HSH2D gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
42286_at²^{, 3}	U95-B	1	0.94	1.00	0.98	0.74	AA280878	0.80	0.88	0.84	1
84981_r_at²^{, 3}	U95-E	1	0.88	1.00	0.98	1.26	T54146	1.00	0.90	0.95	1
1552623_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

HSH2D for expression About GeneDecksing

Data from Genenote (Publications) and GNF BioGPS
About these images

HSH2D gene electronic northern expression

About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.631617

UniProtKB/Swiss-Prot: HSH2D_HUMAN, Q96JZ2

Tissue specificity: Predominantly expressed in spleen and hematopoietic cells such as peripheral blood leukocytes and

weakly expressed in prostate, thymus, heart, small intestine and placenta

Primers:		OriGene genome-wide validated SYBR primer pairs: HSH2D Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay for HSH2D: PPH23413A

SABiosciences Custom PCR Arrays for HSH2D

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for HSH2D gene from 5 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	HSH2D¹	--	hematopoietic SH2 domain containing	75.14(n) 64.45(a)	484852 XM_541968.1 XP_541968.1
chimpanzee (Pan troglodytes)	HSH2D¹	--	hematopoietic SH2 domain containing	99.48(n) 99.07(a)	468760 XM_524147.2 XP_524147.2
cow (Bos taurus)	HSH2D¹	--	hematopoietic SH2 domain containing	73.58(n) 64.63(a)	510693 XM_587867.3 XP_587867.2
mouse (Mus musculus)	Hsh2d^{1 , 5}	8 (34.87 cM)⁵	hematopoietic SH2 domain containing^{1, 5}	67.79(n)¹ 58.72(a)¹	209488¹ NM_197944.1¹ NP_922935.1¹ AK157000⁵ AY319653⁵ (see all 6)
zebrafish (Danio rerio)	hsh2d¹	--	hematopoietic SH2 domain containing	40.1(n) 31.94(a)	548337 NM_001017541.1 NP_001017541.1

About this table Species with no ortholog for HSH2D

ENSEMBL Gene Tree for HSH2D (if available)

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for HSH2D gene

SH2D4A² SH2D2A² SH2D4B²

HSH2D for paralogs About GeneDecksing

(SNPs according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

SNP ID	Valid	Chr 19 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
Genomic Data				Transcription Related Data				Allele Frequencies
			--	--	--		--	--
rs106048^1,2	C,F,A,H,	16264771(-)	`ACACCG/AAGCCC`	1	--	int¹		7		NA WA	16
rs111524^1,2	C,F,A,H,	16265494(-)	`ggtgaT/Caggca`	1	--	int¹		23		NS EA NA WA	1392
rs166948^1,2	C,F,A,H	16261451(-)	`tggcaC/Tgatct`	1	--	int¹		6		NA	16
rs285286^1,2	C,A	16263202(-)	`cccccA/Cggctg`	1	--	int¹		3		NA	6
rs285287^1,2	C,F,A,H,	16261681(-)	`TGAATC/TGtttt`	1	--	int¹		8		NA WA	136
rs285288^1,2	--	16260492(-)	`ttgaaA/Cccagg`	1	--	int¹		0	--	--	--	--
rs285289^1,2	--	16260302(-)	`ggtgcA/Ggtggc`	1	--	int¹		0	--	--	--	--
rs285290^1,2	C,F,O,A,	16259460(+)	`CACCAC/TAAGCT`	1	--	int¹		17		NS EA NA WA	1216
rs378146^1,2	--	16252148(-)	`CCTGGC/GCCAGC`	1	--	int¹		0	--	--	--	--
rs411196^1,2	--	16269120(-)	`gcgatC/Atgcct`	1	--	ut3¹		1		MN	184

About this table

HapMap Linkage Disequilibrium images for HSH2D (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for HSH2D: --

QIAGEN SeqTarget long-range PCR primers for resequencing HSH2D

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section

HSH2D for disorders About GeneDecksing

OMIM: 608349

Human Genome Epidemiology (HuGE) Navigator: HSH2D (3 documents)

Export disorders and mutations for HSH2D gene to outside databases

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶UniProtKB/TrEMBL, and/or ⁷Novoseek)
About This Section

10/13 PubMed articles for HSH2D gene, integrated from 7 sources (see all 13):
(articles sorted by number of sources associating them with HSH2D)

HSH2: a novel SH2 domain-containing adapter protein involved in tyrosine kinase signaling in hematopoietic cells. (PubMed id 11700021)^{1, 2, 3, 7} Oda T.... Yamashita T. (2001)
Cloning and characterization of ALX, an adaptor downstream of CD28. (PubMed id 12960172)^{1, 2, 7} Greene T.A.... Shapiro V.S. (2003)
The ALX Src homology 2 domain is both necessary and sufficient to inhibit T cell receptor/CD28-mediated up-regulation of RE/AP. (PubMed id 15284240)^{1, 2, 7} Shapiro M.J.... Shapiro V.S. (2004)
The carboxyl-terminal segment of the adaptor protein ALX directs its nuclear export during T cell activation. (PubMed id 16169852)^{1, 2} Shapiro M.J.... Shapiro V.S. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)¹ Davila S....Seielstad M. (2010)
Resolvin D1 binds human phagocytes with evidence for proresolving receptors. (PubMed id 20080636)¹ Krishnamoorthy S....Serhan C.N. (2010)
Phosphorylation at serine 318 is not required for inh ibition of T cell activation by ALX. (PubMed id 20471366)¹ Shapiro M.J....Shapiro V.S. (2010)
Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)¹ Bailey S.D....Anand S. (2010)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 84941	HGNC: 24920	AceView: RAB8AandHSH2D	Ensembl:ENSG00000196684	euGenes: HUgn84941
ECgene: HSH2D	H-InvDB: HSH2D

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Intellectual Property for HSH2D gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from XenneX, Inc.)

About This Section

Patent Information for HSH2D gene:
Search GeneIP for patents involving HSH2D

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
About This Section

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	GenScript Custom overexpressing Cell Line Services for HSH2D		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
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GeneCards Homepage - Last full update: 30 Dec 2010 - Incremental updates: 9 Jan 2011 , 10 Jan 2011

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The GeneCards human gene database gene index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

HSH2D gene at Home site.

hostname: www-ab3 db genecards_305 index build: 81e solr: 1.4

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HSH2D Gene

protein-coding GIFtS: 48

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HSH2D Gene

protein-coding GIFtS: 48

Aliases & Descriptionsfor HSH2D gene

Summariesfor HSH2D gene

Genomic Viewsfor HSH2D gene

Proteinsfor HSH2D gene

Protein Domains/Familiesfor HSH2D gene

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Genome Databases showing HSH2D gene

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Aliases &
Descriptions
for HSH2D gene

Summaries
for HSH2D gene

Genomic Views
for HSH2D gene

Proteins
for HSH2D gene

Protein Domains/
Families
for HSH2D gene

Gene Function
for HSH2D gene

Pathways & Interactions
for HSH2D gene

Drugs & Compounds
for HSH2D gene

Transcripts
for HSH2D gene

Expression
for HSH2D gene

Orthologs
for HSH2D gene

Paralogs
for HSH2D gene

Genomic Variants
for HSH2D gene

Disorders & Mutations
for HSH2D gene

Medical News
for HSH2D gene

Publications
for HSH2D gene

Intellectual Property
for HSH2D gene

Products
for HSH2D gene