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IK Gene

protein-coding   GIFtS: 58

GC05P135173
IK cytokine, down-regulator of HLA II
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
IK cytokine, down-regulator of HLA II1 2     chondrosarcoma-associated protein 22
RED2 3 5     protein Red2
Cytokine IK2 3     RD element2
IK factor2 3     MGC597412
prer protein2     RER3
CSA22     Protein RER3

External Ids:    HGNC: 59581   Entrez Gene: 35502   Ensembl: ENSG000001131417   UniProtKB: Q131233   

Export aliases for IK gene to outside databases

Previous GC identifers: GC05P139843 GC05P140610 GC05P140009 GC05P140055 GC05P139992 GC05P139993 GC05P140007 GC05P140028


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for IK:
The protein encoded by this gene was identified by its RED repeat, a stretch of repeated arginine, glutamic acid and
aspartic acid residues. The protein localizes to discrete dots within the nucleus, excluding the nucleolus. Its
function is unknown. This gene maps to chromosome 5; however, a pseudogene may exist on chromosome 2. (provided by
RefSeq)

UniProtKB/Swiss-Prot: RED_HUMAN, Q13123
Function: May bind to chromatin

Gene Wiki entry for IK

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the IK gene promoter:
         AP-1   GATA-2   GATA-1   GATA-3   Max1   CREB   deltaCREB   NF-kappaB1   STAT1alpha   STAT1beta   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for IK

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for IK 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p15-p14|5q31.3   Ensembl cytogenetic band:  5q31.3   HGNC cytogenetic band: 5q31.3

IK Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IK gene location

GeneLoc gene densities for chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P135173:  view genomic region     (about GC identifiers)

Start:
135,172,621 bp from pter
End:
135,187,305 bp from pter
Size:
14,685 bases
Orientation:
plus strand

1 alternative location:
Chr5+ 140,026,643-140,042,064     
RefSeq DNA sequence:
NC_000005.9  NT_029289.11  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: RED_HUMAN, Q13123 (See protein sequence)
Recommended Name: Protein Red  
Size: 557 amino acids; 65602 Da
Subcellular location: Nucleus
Developmental stage: Expressed at similar levels in fetal and adult tissues
Caution: Was originally (PubMed:7970704) thought to be the IK factor, a cytokine involved in the negative regulatory
pathway of constitutive MHC class II antigens expression
Secondary accessions: Q6IPD8

Explore the universe of human proteins at neXtProt for IK: NX_Q13123 

Post-translational modifications:

  • Phosphorylated upon DNA damage, probably by ATM or ATR1
  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_006074.2  

    ENSEMBL proteins: 
    ENSP00000425564 ENSP00000396301 ENSP00000424622 ENSP00000421930 ENSP00000422641 ENSP00000261812 
    ENSP00000426764 


    Human Recombinant Proteins 
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    Novus Biologicals Protein for IK
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins

    3 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615 extracellular space TAS7970704
    GO:0005625 soluble fraction TAS7970704
    GO:0005634 nucleus IEA--
    About this table

    IK for ontologies           About GeneDecksing



    Antibodies for IK: 
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    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for IK 


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    IK for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR012916 RED_N
     IPR012492 RED_C

    Graphical View of Domain Structure for InterPro Entry Q13123

    ProtoNet protein and cluster: Q13123

    1 Blocks protein family: IPB012492 RED-like

    UniProtKB/Swiss-Prot: RED_HUMAN, Q13123
    Similarity: Belongs to the RED family


    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    UniProtKB/Swiss-Prot: RED_HUMAN, Q13123
    Function: May bind to chromatin

    Inhib.
    RNA:
        
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich siRNA Panels and esiRNA and siRNA for IK
    Sigma-Aldrich shRNA for IK
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): IK
    OriGene shRNA RFP (see all 2): IK
    OriGene basic RS shRNA (see all 2): IK
    OriGene siRNA: IK
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of IK 
    miRNA:Browse microRNA Mimics at Sigma-Aldrich
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of IK 
    Search SABiosciences for Assays for microRNAs that regulate IK

    Gene
    Editing:
    Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: IK
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: IK
    OriGene untagged cDNA clones in CMV expression vector (see all 2): IK
    OriGene 3'-UTR clone: IK 
    Browse MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for IK 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:
      
    GenScript Custom overexpressing Cell Line Services for IK 

    Genatlas biochemistry entry for IK:
    cytokine IK (19kDa) downregulating HLA class II expression on the cell surface

    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section

        SABiosciences Pathway-Focused PCR Array including IK: PAHS-3803A 

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IK

    5/573 Interacting proteins for IK (Q131232) via UniProtKB, MINT, and/or STRING (see all 573)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CHD3Q128732MINT-7945693 MINT-64118
    ABCF1Q8NE712MINT-7945693
    ABCF3Q9NUQ82MINT-7945693
    ACIN1Q9UKV32MINT-7945693
    ACTBP607092MINT-7945693
    About this table

    2 Gene Ontology (GO) biological process terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006955 immune response TAS7970704
    GO:0007267 cell-cell signaling TAS7970704
    About this table

    IK for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section
    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for IK


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section

    Inhib.
    RNA:
         
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich siRNA Panels and esiRNA and siRNA for IK
    Sigma-Aldrich shRNA for IK
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): IK
    OriGene shRNA RFP (see all 2): IK
    OriGene basic RS shRNA (see all 2): IK
    OriGene siRNA: IK
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of IK 
    miRNA: Browse microRNA Mimics at Sigma-Aldrich
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of IK 
    Search SABiosciences for Assays for microRNAs that regulate IK
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: IK
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: IK
    OriGene untagged cDNA clones in CMV expression vector (see all 2): IK
    OriGene 3'-UTR Clone: IK 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for IK 
    Primers: OriGene genome-wide validated SYBR primer pairs: IK
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for IK: PPH19888A

    REFSEQ mRNAs for IK gene: 

    NM_006083.3  

    Additional cDNA sequence: 

    AF182645.1 AJ005579.1 AK225924.1 AK293626.1 AK308730.1 AK312363.1 AL050296.1 AY007094.1 
    BC013005.2 BC051295.1 BC071964.1 CR612510.1 S74221.1 

    24/31 DOTS entries (see all 31):

    DT.418420  DT.40248441  DT.92459896  DT.100845637  DT.100845634  DT.95170073  DT.121031617  DT.100059633 
    DT.95170088  DT.120833500  DT.120833425  DT.120833416  DT.120833479  DT.95170072  DT.100043123  DT.100845635 
    DT.120833460  DT.120833503  DT.121031572  DT.319462  DT.100839133  DT.100845629  DT.100059632  DT.120833409 

    24/295 AceView cDNA sequences (see all 295):

    CK299491 AA953244 CA442072 BU741196 AA436395 BM806610 BQ102505 CA434844 
    BC071964 AW238950 AI831143 BQ019101 BM726920 BM667779 BG940194 AA531032 
    CA434842 AA235321 W58454 AA135202 BM805841 AW075673 BU952579 CD513733 

    highest scoring ESTs for IK:

    AJ005579 AW008244 S74221 AA069271 AA099986 AA100362 AA169391 AA186867 AA292506 AA488675 

    Unigene Cluster for IK:

    IK cytokine, down-regulator of HLA II
    Hs.421245  [show with all ESTs]
    Unigene Representative Sequence: AK225924


    GeneLoc Exon Structure

    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000513256 ENST00000417647(uc011czk.1 uc003lgq.2) ENST00000507593
    ENST00000503332 ENST00000523672 ENST00000512827 ENST00000518969 ENST00000508301
    ENST00000261812 ENST00000502899 ENST00000515015 ENST00000515592

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    IK expression in normal and diseased human tissues

    1  / 2  / 3

    6 probe-sets matching IK gene

    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    87819_at2, 3 U95-E 1 1.00 1.00 0.93 1.30 AW008244 1.00 1.00 1.00 1
    218_at2, 3 U95-A 2 1.00 0.97 0.97 0.93 S74221 1.00 1.00 1.00 1
    38046_at2, 3 U95-A 2 1.00 0.91 0.76 0.78 AJ005579 1.00 1.00 1.00 1
    32377_at2, 3 U95-A 1 0.50 1.00 0.38 0.21 AI538199 0.60 1.00 0.82 1
    200066_at2, 3 U133-B 2 1.00 0.91 -- -- AF182645 0.80 1.00 0.91 1
    200066_at2 U133Plus2 2 1.00 0.91 -- -- -- -- -- -- --
    About this table

    IK for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    IK gene expression
    IK gene electronic northern expression
    IK gene sage expression
    About these images

    CGAP SAGE TAG: GCTGTGGATA

    SOURCE GeneReport for Unigene cluster: Hs.421245

    Expression variation in blood from EXPOLDB for IK

    UniProtKB/Swiss-Prot: RED_HUMAN, Q13123
    Tissue specificity: Ubiquitous

    Primers: OriGene genome-wide validated SYBR primer pairs: IK
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for IK: PPH19888A
        SABiosciences Expression via Pathway-Focused PCR Array including IK: PAHS-3803A 


    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section

    Orthologs for IK gene from 5/13 species (see all 13)
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    IK1   -- IK cytokine, down-regulator of HLA II 91.9(n)
    98.35(a)
    607109  XM_843700.1  XP_848793.1 
    rat
    (Rattus norvegicus)
    Ik1   -- IK cytokine 90.31(n)
    98.56(a)
    291659  NM_001005537.1  NP_001005537.1 
    mouse
    (Mus musculus)
    Ik1 , 5 18 (19.46 cM)5
    IK cytokine1, 5 90.84(n)1
    98.38(a)1
    240101  NM_011879.11  NP_036009.11 
     AI7903285  AJ0061305  (see all 24)
    chicken
    (Gallus gallus)
    IK1   -- IK cytokine, down-regulator of HLA II 84.39(n)
    95.66(a)
    416133  NM_001006145.1  NP_001006145.1 
    zebrafish
    (Danio rerio)
    wufb54c032   -- wufb54c03 78.09(n) 322241  BC049322.1 
    About this table        Species with no ortholog for IK

    ENSEMBL Gene Tree for IK (if available)

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
    Paralogs for IK gene
    RDBP2  

    IK for paralogs           About GeneDecksing


    Pseudogenes
    1 related pseudogene



    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/106 NCBI SNPs in IK are shown (see all 106)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 5 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ----------
    rs48011,2
    C,F,140041960(+) CCCACT/GGTTTT 1 -- ut31 ese37Minor allele frequency- G:0.32MN NS NA EA WA 704
    rs7785951,2
    C,A,140036681(+) tactcG/Agaagg 1 -- int13Minor allele frequency- A:0.50NA 6
    rs7785961,2
    C,F,O,A,140037272(+) GAGAAA/GCCTTA 1 -- int1 trp316Minor allele frequency- G:0.49EA MN NS NA WA 2486
    rs7785971,2
    C,F,O,A,140040665(+) AGTAAG/ACAAGC 1 -- int113Minor allele frequency- A:0.44MN NS EA NA WA 952
    rs7785981,2
    C,F,140040921(+) CCAAGT/CTCTTT 1 -- int18Minor allele frequency- C:0.15EA NA MN WA 556
    rs8013991,2
    C,F,O,A,140034844(+) CAAAAT/CTTGGA 1 -- int123Minor allele frequency- C:0.47EA NA NS WA 1360
    rs15830051,2
    C,F,A,140031537(-) CCACAC/TCAATA 1 -- int114Minor allele frequency- T:0.46NA NS EA WA 780
    rs18642541,2
    C,A140032947(+) gctcaC/Tggcaa 1 -- int13Minor allele frequency- T:0.50NA WA 6
    rs19626481,2
    C,A140030306(-) TGGGCG/ACCTGT 1 -- int13Minor allele frequency- A:0.50NA 6
    rs19626491,2
    C,A,140030243(-) cggagA/Tttgca 1 -- int14Minor allele frequency- T:0.25NA WA 8
    About this table

    HapMap Linkage Disequilibrium images for IK (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for IK: --

    QIAGEN SeqTarget long-range PCR primers for resequencing IK 

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    IK for disorders           About GeneDecksing

    OMIM: 600549

    Human Genome Epidemiology (HuGE) Navigator: IK (110 documents)

    Export disorders and mutations for IK gene to outside databases

    (Possibly Related Articles in Doctor's Guide)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/25 PubMed articles for IK gene, integrated from 7 sources (see all 25):
    (articles sorted by number of sources associating them with IK)
    1. A new cytokine (IK) down-regulating HLA class II: monoclonal antibodies, cloning and chromosome localization. (PubMed id 7970704)1, 2, 3, 7 Krief P.... Azzarone B. (1994)
    2. Isolation, sequencing and expression of RED, a novel human gene encoding an acidic-basic dipeptide repeat. (PubMed id 10216252)1, 2 Assier E.... Rich T. (1999)
    3. Implication of a new molecule IK in CD34+ hematopoietic progenitor cell proliferation and differentiation. (PubMed id 9160666)1, 7 Cao L.X....Krief P. (1997)
    4. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (2010)
    5. An approach based on a genome-wide association study reveals candidate loci for narcolepsy. (PubMed id 20677014)1 Shimada M....Tokunaga K. (2010)
    6. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (2009)
    7. Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (2009)
    8. HBEGF, SRA1, and IK: Three cosegregating genes as det erminants of cardiomyopathy. (PubMed id 19064678)1 Friedrichs F....Stoll M. (2009)
    9. Fine mapping of the CELIAC2 locus on chromosome 5q31- q33 in the Finnish and Hungarian populations. (PubMed id 19845895)1 Koskinen L.L....Saavalainen P. (2009)
    10. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 3550 HGNC: 5958 AceView: IK.1 Ensembl:ENSG00000113141 euGenes: HUgn3550
    ECgene: IK H-InvDB: IK

    (According to HUGE)
    About This Section
      --

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
      --

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
    About This Section
    Patent Information for IK gene:
    Search GeneIP for patents involving IK

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
    Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
    About This Section

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     Predesigned and custom siRNAs for IK Antibodies for IK
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