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IRAK1BP1 Gene

protein-coding GIFtS: 47

GC06P076770

interleukin-1 receptor-associated kinase 1 binding protein 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

		Products

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases & Descriptions
interleukin-1 receptor-associated kinase 1 binding protein 1¹ ²		4921528N06Rik²
AIP70¹ ²		interleukin-1 receptor-associated kinase 1-binding protein 1²
SIMPL¹ ²		MGC138458²
ActA binding protein 3²		MGC138460²

External Ids:	HGNC: 17368¹	Entrez Gene: 134728²	Ensembl: ENSG00000146243⁷	UniProtKB: Q5VVH5³

Export aliases for IRAK1BP1 gene to outside databases

Previous GC identifers: GC06P079527 GC06P079572 GC06P079633

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: IKBP1_HUMAN, Q5VVH5

Function: Component of the IRAK1-dependent TNFRSF1A signaling pathway that leads to NF-kappa-B activation and is

required for cell survival. Acts by enhancing RELA transcriptional activity (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the IRAK1BP1 gene promoter:
         NF-kappaB1   NF-kappaB   C/EBPbeta   Meis-1   Pax-5   ATF-2   deltaCREB   CREB   Chx10   FOXJ2 (long isoform)
         Other transcription factors

Search SABiosciences Chromatin IP Primers for IRAK1BP1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for IRAK1BP1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q14-q15 Ensembl cytogenetic band: 6q14.1 HGNC cytogenetic band: 6q14-q15

IRAK1BP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IRAK1BP1 gene location

GeneLoc gene densities for chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06P076770: view genomic region (about GC identifiers)

Start:	76,770,876 bp from pter
End:	76,802,187 bp from pter
Size:	31,312 bases
Orientation:	plus strand

1 alternative location:

Chr6+ 79,577,189-79,608,320

RefSeq DNA sequence:

NC_000006.11 NT_007299.13

(According to ¹UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: IKBP1_HUMAN, Q5VVH5 (See protein sequence)

Recommended Name: Interleukin-1 receptor-associated kinase 1-binding protein 1

Size: 260 amino acids; 29106 Da

Subunit: Interacts with IRAK1 and RELA. Interacts with HSPA8 and HSPA1 (By similarity)

Subcellular location: Cytoplasm (By similarity). Nucleus (By similarity)

Explore the universe of human proteins at neXtProt for IRAK1BP1: NX_Q5VVH5

Post-translational modifications:

Phosphorylation at Ser-56 and/or Ser-62 is required for full activity. Phosphorylated on at least one of Ser-235,

Thr-237, Ser-242 and Thr-247 upon TNF-alpha activation, which favors nuclear translocation (By similarity)¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_001010844.1

ENSEMBL proteins:

ENSP00000358956

Human Recombinant Proteins

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2 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--
GO:0005737	cytoplasm	IEA	--

About this table

IRAK1BP1 for ontologies About GeneDecksing

Antibodies for IRAK1BP1:

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	Browse antibodies at Epitomics

Assays for IRAK1BP1:

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	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for IRAK1BP1
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for IRAK1BP1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

IRAK1BP1 for domains About GeneDecksing

1 InterPro domain/family:

IPR007497 DUF541

Graphical View of Domain Structure for InterPro Entry Q5VVH5

ProtoNet protein and cluster: Q5VVH5

UniProtKB/Swiss-Prot: IKBP1_HUMAN, Q5VVH5

Domain: The intrinsically disordered region interacts with HSPA1 and HSPA8 (By similarity)

Similarity: Belongs to the IRAK1BP1 family

(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: IKBP1_HUMAN, Q5VVH5

Function: Component of the IRAK1-dependent TNFRSF1A signaling pathway that leads to NF-kappa-B activation and is

required for cell survival. Acts by enhancing RELA transcriptional activity (By similarity)

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Browse Nano Scale siRNA at Sigma-Aldrich Sigma-Aldrich esiRNA and siRNA for IRAK1BP1 Sigma-Aldrich shRNA for IRAK1BP1
		OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): IRAK1BP1 OriGene shRNA RFP (see all 2): IRAK1BP1 OriGene basic RS shRNA (see all 2): IRAK1BP1 OriGene siRNA (see all 2): IRAK1BP1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of IRAK1BP1

miRNA:		Sigma-Aldrich microRNA Mimics for IRAK1BP1 Browse microRNA target validation systems at Sigma-Aldrich
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of IRAK1BP1
		Search SABiosciences for Assays for microRNAs that regulate IRAK1BP1

Gene
Editing:

Browse CompoZr Knockout ZFN at Sigma-Aldrich

Clones:		Browse Clones for the Expression of Recombinant Proteins Available from Millipore
		Browse iPSC Reprogramming Factors at Sigma-Aldrich
		OriGene GFP tagged cDNA clones in CMV expression vector: IRAK1BP1 OriGene Myc/DDK tagged cDNA clones in CMV expression vector: IRAK1BP1 OriGene untagged cDNA clones in CMV expression vector: IRAK1BP1 OriGene 3'-UTR clone: IRAK1BP1 Browse MicroRNA Expression Plasmids
		GenScript cDNA clone with any tag delivered in your preferred vector: IRAK1BP1
		Browse Sino Biological Human cDNA Clones

Cell
Lines:

GenScript Custom overexpressing Cell Line Services for IRAK1BP1

1 Gene Ontology (GO) molecular function term (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IEA	--

About this table

IRAK1BP1 for ontologies About GeneDecksing

Animal Models: 1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Irak1bp1):

no phenotypic analysis

IRAK1BP1 for phenotypes About GeneDecksing

(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section

SABiosciences Custom Pathway-Focused PCR Arrays for IRAK1BP1

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for IRAK1BP1

1 Interacting protein for IRAK1BP1 (ENSP00000358956³) via UniProtKB, MINT, and/or STRING

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
IRAK1	ENSP00000358997³	STRING: ENSP00000358997

About this table

2 Gene Ontology (GO) biological process terms (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007249	I-kappaB kinase/NF-kappaB cascade	ISS	--
GO:0045449	regulation of transcription	IEA	--

About this table

IRAK1BP1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse Small Molecules at Sigma-Aldrich

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for IRAK1BP1

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Browse Nano Scale siRNA at Sigma-Aldrich Sigma-Aldrich esiRNA and siRNA for IRAK1BP1 Sigma-Aldrich shRNA for IRAK1BP1
		OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): IRAK1BP1 OriGene shRNA RFP (see all 2): IRAK1BP1 OriGene basic RS shRNA (see all 2): IRAK1BP1 OriGene siRNA (see all 2): IRAK1BP1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of IRAK1BP1

miRNA:		Sigma-Aldrich microRNA Mimics for IRAK1BP1 Browse microRNA target validation systems at Sigma-Aldrich
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of IRAK1BP1
		Search SABiosciences for Assays for microRNAs that regulate IRAK1BP1

Clones:		Browse FLAG tag genes at Sigma-Aldrich
		OriGene GFP tagged cDNA clones in CMV expression vector: IRAK1BP1 OriGene Myc/DDK tagged cDNA clones in CMV expression vector: IRAK1BP1 OriGene untagged cDNA clones in CMV expression vector: IRAK1BP1 OriGene 3'-UTR Clone: IRAK1BP1 Browse OriGene MicroRNA Expression Plasmids
		GenScript cDNA clone with any tag delivered in your preferred vector: IRAK1BP1

Primers:		OriGene genome-wide validated SYBR primer pairs: IRAK1BP1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay for IRAK1BP1: PPH22928A

REFSEQ mRNAs for IRAK1BP1 gene:

NM_001010844.1

Additional cDNA sequence:

AK098678.1 AK309003.1 BC112253.1 BC112255.1

13 DOTS entries:

DT.97811400 DT.99927665 DT.95322922 DT.95227509 DT.95348514 DT.103522 DT.121387442 DT.100675523

DT.444138 DT.75177627 DT.95170404 DT.97840245 DT.97858748

24/61 AceView cDNA sequences (see all 61):

AL521825 BX387112 BM127007 BF513853 AI917638 AI761886 AA480250 BX103697

AA679673 BM830836 AW450696 AI379905 AK098678 BQ435042 BU561117 CB321683

AA635174 BF056102 BI562425 BX107880 BU195215 BE501177 BX403291 AA644376

highest scoring ESTs for IRAK1BP1:

AI478629 AI265895 AI379905 AI498886 AI761886 AK098678 AW450696 BF513853 BG773243 BM127007

Unigene Cluster for IRAK1BP1:

Interleukin-1 receptor-associated kinase 1 binding protein 1

Hs.656212 [show with all ESTs]

Unigene Representative Sequence: AK309003

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for IRAK1BP1

ExUns:	1a	·	1b	·	1c	^	2	^	3	^	4	^	5	^	6	^	7	^	8a	·	8b	^	9
SP1:									-										-		-
SP2:							-		-
SP3:							-		-				-		-		-
SP4:							-
SP5:

About this scheme

ECgene alternative splicing isoforms for IRAK1BP1
1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000369940(uc003pim.2 uc003pin.2 uc010kbg.1)

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

IRAK1BP1 expression in normal and diseased human tissues

¹ / ² / ³

3 probe-sets matching IRAK1BP1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
83847_at²^{, 3}	U95-E	1	0.81	1.00	1.00	1.00	AI478629	1.00	1.00	1.00	1
238599_at²^{, 3}	U133-B	1	0.73	1.00	--	--	AI168124	0.60	1.00	0.82	1
238599_at²	U133Plus2	1	0.73	1.00	--	--	--	--	--	--	--

About this table

IRAK1BP1 for expression About GeneDecksing

Data from Genenote (Publications) and GNF BioGPS
About these images

IRAK1BP1 gene electronic northern expression

About these images

CGAP SAGE TAG: AATCCCACAT

SOURCE GeneReport for Unigene cluster: Hs.656212

Expression variation in blood from EXPOLDB for IRAK1BP1

Primers:		OriGene genome-wide validated SYBR primer pairs: IRAK1BP1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay for IRAK1BP1: PPH22928A

SABiosciences Custom PCR Arrays for IRAK1BP1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for IRAK1BP1 gene from 5/8 species (see all 8)

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	IRAK1BP1¹	--	interleukin-1 receptor-associated kinase 1 binding more	89.87(n) 90(a)	481892 XM_539013.2 XP_539013.2
cow (Bos taurus)	IRAK1BP1¹	--	interleukin-1 receptor-associated kinase 1 binding more	89.23(n) 87.69(a)	782235 XM_001249981.1 XP_001249982.1
rat (Rattus norvegicus)	Irak1bp1¹	--	interleukin-1 receptor-associated kinase 1 binding more	81.34(n) 79.54(a)	300862 XM_217210.4 XP_217210.3
mouse (Mus musculus)	Irak1bp1^{1 , 5}	9 (45.16 cM)⁵	interleukin-1 receptor-associated kinase 1 binding more^{1, 5}	83.66(n)¹ 82.24(a)¹	65099¹ NM_022986.3¹ NP_075362.2¹ AF093135⁵ AI851240⁵ (see all 16)
chicken (Gallus gallus)	IRAK1BP1¹	--	interleukin-1 receptor-associated kinase 1 binding more	65.86(n) 58.23(a)	421857 XM_419874.1 XP_419874.1

About this table Species with no ortholog for IRAK1BP1

ENSEMBL Gene Tree for IRAK1BP1 (if available)

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(SNPs according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

SNP ID	Valid	Chr 6 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
Genomic Data				Transcription Related Data				Allele Frequencies
			--	--	--		--	--
rs1021988^1,2	C,H,	79592661(-)	`ttttgG/Aaataa`	1	--	int¹		5		NA EA WA	166
rs2135772^1,2	C,A,	79592048(-)	`tatttA/Cttttg`	1	--	int¹		8		NA EA WA	220
rs2174743^1,2	C,F,A,	79591805(-)	`cactgT/Ctattg`	1	--	int¹		14		NS EA NA WA	764
rs2321895^1,2	C	79597361(+)	`ctgggT/Cgacag`	1	--	int¹		5		NA	10
rs4055605^1,2	C	79595171(+)	`ACTTATCTTA/- ACAAA`	1	--	int¹		1		NA	2
rs4327648^1,2	C,F,H,	79606615(+)	`TCTCTT/CTGCTA`	1	--	int¹		12		NS NA EA WA	594
rs4706078^1,2	C,A,H	79582806(+)	`tgtttC/Ttacta`	1	--	int¹		0	--	--	--	--
rs4706740^1,2	H	79582662(+)	`TAAGAA/CCCTTA`	1	--	int¹		4		NS EA	416
rs6454089^1,2	C,F,H,	79584102(+)	`GATTCC/TGTATT`	1	--	int¹		12		NS EA NA WA	536
rs6908105^1,2	C,F,A,	79595097(+)	`CAGGCA/GGAAAA`	2	A	ref¹ syn¹		15		NS EA NA WA	1154

About this table

HapMap Linkage Disequilibrium images for IRAK1BP1 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for IRAK1BP1: --

QIAGEN SeqTarget long-range PCR primers for resequencing IRAK1BP1

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶UniProtKB/TrEMBL, and/or ⁷Novoseek)
About This Section

6 PubMed articles for IRAK1BP1 gene integrated from 7 sources:
(articles sorted by number of sources associating them with IRAK1BP1)

SIMPL is a tumor necrosis factor-specific regulator of nuclear factor-kappaB activity. (PubMed id 11096118)^{1, 2, 3} Vig E....Harrington M.A. (2001)
Phosphorylation of SIMPL modulates RelA-associated NF-kappaB-dependent transcription. (PubMed id 17079333)¹ Luo Y....Harrington M.A. (2007)
Tumor necrosis factor alpha induction of NF-kappaB requires the novel coactivator SIMPL. (PubMed id 15485901)¹ Kwon H.J....Harrington M.A. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)² Mungall A.J.... Beck S. (2003)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 134728	HGNC: 17368	AceView: IRAK1BP1	Ensembl:ENSG00000146243	euGenes: HUgn134728
ECgene: IRAK1BP1	H-InvDB: IRAK1BP1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Intellectual Property for IRAK1BP1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from XenneX, Inc.)

About This Section

Patent Information for IRAK1BP1 gene:
Search GeneIP for patents involving IRAK1BP1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
About This Section

	Millipore Custom Antibody & Bulk Services
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	Predesigned and custom siRNAs for IRAK1BP1		Antibodies for IRAK1BP1
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	"Your Favorite Gene" Pathways and Molecular Interaction Networks		Browse Nano Scale siRNA at Sigma-Aldrich
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	shRNA in GFP-retroviral vector
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	Custom Immunoassay Development
	Fluorogenic Cell Assay Kits
	miRNA Primers for qPCR Assays
	3' UTR Clones for miRNA Target Studies
	miRNA Expression Plasmids

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of IRAK1BP1
	SeqTarget long-range PCR primers for resequencing IRAK1BP1
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for IRAK1BP1
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of IRAK1BP1

	GenScript Custom Purified and Recombinant Proteins Services for IRAK1BP1		GenScript cDNA clones with any tag delivered in your preferred vector for IRAK1BP1
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Search for Antibodies & Assays

	Regulatory tfbs in IRAK1BP1 promoter
	Search Chromatin IP Primers for IRAK1BP1
	RT² qPCR Primer Assay for IRAK1BP1
	GNC Network for IRAK1BP1
	Search for Assays for microRNAs that regulate IRAK1BP1
	SABiosciences Custom PCR Arrays for IRAK1BP1

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	Antibodies for IRAK1BP1
	Proteins for IRAK1BP1
	Lysates for IRAK1BP1

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ELISAs and CLIAs for IRAK1BP1

GeneCards Homepage - Last full update: 30 Dec 2010 - Incremental updates: 10 Jan 2011 , 10 Jan 2011

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The GeneCards human gene database gene index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

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Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

IRAK1BP1 gene at Home site.

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IRAK1BP1 Gene

protein-coding GIFtS: 47

Aliases &
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for IRAK1BP1 gene

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for IRAK1BP1 gene

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for IRAK1BP1 gene

Proteins
for IRAK1BP1 gene

Protein Domains/
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for IRAK1BP1 gene

Gene Function
for IRAK1BP1 gene

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for IRAK1BP1 gene

Drugs & Compounds
for IRAK1BP1 gene

Transcripts
for IRAK1BP1 gene

Expression
for IRAK1BP1 gene

Orthologs
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Paralogs
for IRAK1BP1 gene

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IRAK1BP1 Gene

protein-coding GIFtS: 47

Aliases & Descriptionsfor IRAK1BP1 gene

Summariesfor IRAK1BP1 gene

Genomic Viewsfor IRAK1BP1 gene

Proteinsfor IRAK1BP1 gene

Protein Domains/Familiesfor IRAK1BP1 gene

Gene Functionfor IRAK1BP1 gene

Pathways & Interactionsfor IRAK1BP1 gene

Drugs & Compoundsfor IRAK1BP1 gene

Transcriptsfor IRAK1BP1 gene

Expression for IRAK1BP1 gene

Orthologsfor IRAK1BP1 gene

Paralogsfor IRAK1BP1 gene

Genomic Variantsfor IRAK1BP1 gene

Disorders & Mutationsfor IRAK1BP1 gene

Medical Newsfor IRAK1BP1 gene

Publicationsfor IRAK1BP1 gene

External Searches for IRAK1BP1 gene

Genome Databases showing IRAK1BP1 gene

Other Databases showing IRAK1BP1 gene

Specialized Databases showing IRAK1BP1 gene

Intellectual Propertyfor IRAK1BP1 gene

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Aliases &
Descriptions
for IRAK1BP1 gene

Summaries
for IRAK1BP1 gene

Genomic Views
for IRAK1BP1 gene

Proteins
for IRAK1BP1 gene

Protein Domains/
Families
for IRAK1BP1 gene

Gene Function
for IRAK1BP1 gene

Pathways & Interactions
for IRAK1BP1 gene

Drugs & Compounds
for IRAK1BP1 gene

Transcripts
for IRAK1BP1 gene

Expression
for IRAK1BP1 gene

Orthologs
for IRAK1BP1 gene

Paralogs
for IRAK1BP1 gene

Genomic Variants
for IRAK1BP1 gene

Disorders & Mutations
for IRAK1BP1 gene

Medical News
for IRAK1BP1 gene

Publications
for IRAK1BP1 gene

Intellectual Property
for IRAK1BP1 gene

Products
for IRAK1BP1 gene