Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Genomic Views
Intellectual Property
Medical News
Orthologs
Paralogs
Pathways/Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Aliases & Descriptionsfor IRGQ gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section Aliases & Descriptions immunity-related GTPase family, Q1 2 FLJ125212 immunity-related GTPase family, Q11 2 immunity-related GTPase family Q protein2 IRGQ12 3 FLJ388492 FKSG271 FLJ427962 FLJ467132
Export aliases for IRGQ gene to outside databases Previous GC identifers: GC19M048792 GC19M044090
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Genomic Views
Intellectual Property
Medical News
Orthologs
Paralogs
Pathways/Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Summariesfor IRGQ gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section --
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Genomic Views
Intellectual Property
Medical News
Orthologs
Paralogs
Pathways/Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Genomic Viewsfor IRGQ gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60) ,
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences )About This Section Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the IRGQ gene promoter: NF-kappaB1 AhR NF-kappaB c-Myb GR-beta GR-alpha STAT1 STAT1alpha STAT1beta ARP-1 Other transcription factors Search SABiosciences Chromatin IP Primers for IRGQ Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for IRGQ
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 19q13.31 Ensembl cytogenetic band: 19q13.31 HGNC cytogenetic band: 19q13.31 IRGQ Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure
GeneLoc location for GC19M040519: view genomic region
(about GC identifiers )
Start:
40,519,278 bp from pter
End:
40,531,046 bp from pter
Size:
11,769 bases
Orientation:
minus strand
1 alternative location : Chr 19- 44,088,521-44,100,287
RefSeq DNA sequence: NC_000019.9 NT_011109.16
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Genomic Views
Intellectual Property
Medical News
Orthologs
Paralogs
Pathways/Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Proteinsfor IRGQ gene
(According to
1 UniProtKB ,
neXtProt ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological , and/or
ProSpec ,
Biochemical Assays by
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene ,
Antibodies by
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals , and/or
Epitomics )
About This Section UniProtKB/Swiss-Prot: IRGQ_HUMAN, Q8WZA9 (See
protein sequence )Recommended Name: Immunity-related GTPase family Q protein Size : 623 amino acids; 62717 Da
Secondary accessions : B2RNP3Explore the universe of human proteins at neXtProt for IRGQ: NX_Q8WZA9 Post-translational modifications:
View phosphorylation sites using PhosphoSite 2
REFSEQ proteins: NP_001007562.1 ENSEMBL proteins: ENSP00000387535 ENSP00000300809 Human Recombinant Proteins Antibodies for IRGQ: Assays for IRGQ:
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Genomic Views
Intellectual Property
Medical News
Orthologs
Paralogs
Pathways/Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Protein
Domains/ Familiesfor IRGQ gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section ProtoNet protein and cluster: Q8WZA9
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Genomic Views
Intellectual Property
Medical News
Orthologs
Paralogs
Pathways/Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Gene Functionfor IRGQ gene
(According to UniProtKB ,
IUBMB ,and/or
Genatlas , Animal models from MGI Dec 24 2010,
shRNA from
OriGene ,
Sigma-Aldrich ,
RNAi from
Millipore ,
siRNAs from
Sigma-Aldrich ,
OriGene ,
Qiagen ,
Super-pooled esiRNAs from Sigma-Aldrich ,
microRNA from Sigma-Aldrich ,
Qiagen ,
SABiosciences ,
Clones from Millipore ,
Sigma-Aldrich ,
OriGene ,
GenScript ,
Sino Biological ,
Cell Lines from GenScript ,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene .)
About This Section 1 Gene Ontology (GO) molecular function term (GO ID links to tree view) :
About this table
IRGQ for ontologies About GeneDecksing
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Genomic Views
Intellectual Property
Medical News
Orthologs
Paralogs
Pathways/Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Pathways & Interactionsfor IRGQ gene
(Pathways according to
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
PCR Arrays from
SABiosciences ,
Proteins Network according to
SABiosciences ,
Sigma-Aldrich ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene) .
About This Section SABiosciences Custom Pathway-Focused PCR Arrays for IRGQ Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IRGQ 1 Interacting protein for IRGQ (Q8WZA9 1 ) via UniProtKB, MINT, and/or STRING About this table
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Genomic Views
Intellectual Property
Medical News
Orthologs
Paralogs
Pathways/Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Drugs & Compoundsfor IRGQ gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
About This Section Browse Tocris compounds for IRGQ
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Genomic Views
Intellectual Property
Medical News
Orthologs
Paralogs
Pathways/Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Transcriptsfor IRGQ gene (GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
Millipore ,
siRNAs from
Sigma-Aldrich ,
OriGene ,
Qiagen ,
Super-pooled esiRNAs from Sigma-Aldrich ,
shRNA from
Sigma-Aldrich ,
OriGene ,
microRNA from Sigma-Aldrich ,
Qiagen ,
SABiosciences ,
Tagged/untagged cDNA clones from
OriGene ,
Sigma-Aldrich ,
GenScript ,
Primers from
OriGene and/or
SABiosciences )About This Section REFSEQ mRNAs for IRGQ gene: NM_001007561.2
Additional cDNA sequence: AF322648.1 AK022583.1 AK096168.1 AK124786.1 AK128554.1 BC137020.1 BC137021.1 BC144451.1
7 DOTS entries : DT.452174 DT.95350758 DT.421587 DT.207782 DT.95367690 DT.40235939 DT.87016288
24/374 AceView cDNA sequences (see all 374 ):
BM451621 BQ058190 BM698936 BX452522 BM831569 AK128554 BU178401 BE044126 BQ066716 BM928576 F08201 AL520680 AA426207 BM831688 BI913668 CA395701 BQ056064 AA722476 BQ643143 AI168181 AL134428 CR610347 BQ896139 BQ682697
highest scoring ESTs for IRGQ :AI346570 AA584134 AA775746 AF322648 AA583892 AI125175 AW173751 AW410194 BE298151 BI767180 Unigene Cluster for IRGQ:
Immunity-related GTPase family, Q Hs.6217 [show with all ESTs ] Unigene Representative Sequence: NM_001007561 GeneLoc Exon Structure 2 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000422989 (uc002oww.2 uc010eiv.2 ) ENST00000300809
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Genomic Views
Intellectual Property
Medical News
Orthologs
Paralogs
Pathways/Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Expression for IRGQ gene
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Primers from
OriGene and/or
SABiosciences
)
About This Section IRGQ expression in normal and diseased human tissues 1 / 2 / 3
14 probe-sets matching IRGQ gene
Affymetrix probe-set
Array
GeneAnnot data
GeneNote data
GeneTide data
# genes
Sensitivity
Specificity
Correlation
Length
Gb_Accession
Consensus
Uniqueness
Score
Rank
91071_at2 , 3
U95-D
1
1.00
1.00
0.69
0.93
AI346570
0.80
1.00
0.91
1
64488_at2 , 3
U133-C
1
1.00
1.00
0.12
1.28
AW003091
0.20
1.00
0.72
1
47028_at2
U95-B
1
0.69
1.00
0.68
0.80
--
--
--
--
--
87495_at2 , 3
U95-E
1
0.44
1.00
0.71
1.01
AI734079
0.20
1.00
0.72
1
221877_at2 , 3
U133-A
1
1.00
1.00
--
--
BF508835
0.20
1.00
0.72
1
64488_at2 , 3
U133-A
1
1.00
1.00
--
--
AW003091
0.20
1.00
0.72
1
242183_at2 , 3
U133-B
1
0.91
1.00
--
--
AL134428
0.20
1.00
0.72
1
239177_at2
U133-B
1
0.46
1.00
--
--
--
--
--
--
--
221877_at2
U133Plus2
1
1.00
1.00
--
--
--
--
--
--
--
64488_at2
U133Plus2
1
1.00
1.00
--
--
--
--
--
--
--
1555833_a_at2
U133Plus2
1
1.00
1.00
--
--
--
--
--
--
--
242183_at2
U133Plus2
1
0.91
1.00
--
--
--
--
--
--
--
1569310_at2
U133Plus2
1
0.55
1.00
--
--
--
--
--
--
--
239177_at2
U133Plus2
1
0.46
1.00
--
--
--
--
--
--
--
About this table
IRGQ for expression About GeneDecksing Data from
Genenote  
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: AAGGACACAT SOURCE GeneReport for Unigene cluster: Hs.6217 SABiosciences Custom PCR Arrays for IRGQ
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Genomic Views
Intellectual Property
Medical News
Orthologs
Paralogs
Pathways/Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Orthologsfor IRGQ gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
About This Section
Orthologs for IRGQ gene from 5 species
About this table Species with no ortholog for IRGQ ENSEMBL Gene Tree for IRGQ (if available)
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Genomic Views
Intellectual Property
Medical News
Orthologs
Paralogs
Pathways/Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Paralogsfor IRGQ gene (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section --
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Genomic Views
Intellectual Property
Medical News
Orthologs
Paralogs
Pathways/Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Genomic Variantsfor IRGQ gene (SNPs according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Resequencing Primers from Qiagen )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Chr 19 pos Sequence Recs AA Chg Type More Recs Allele freq Pop Total sample More
About this table HapMap Linkage Disequilibrium images for IRGQ (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for IRGQ: --
QIAGEN SeqTarget long-range PCR primers for resequencing IRGQ
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Genomic Views
Intellectual Property
Medical News
Orthologs
Paralogs
Pathways/Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Disorders & Mutationsfor IRGQ gene
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
LSDB, HGMD, GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
IRGQ for disorders About GeneDecksing Human Genome Epidemiology (HuGE) Navigator: IRGQ (1 document)Export disorders and mutations for IRGQ gene to outside databases
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Genomic Views
Intellectual Property
Medical News
Orthologs
Paralogs
Pathways/Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Medical Newsfor IRGQ gene (Possibly Related Articles in
Doctor's Guide )
About This Section --
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Genomic Views
Intellectual Property
Medical News
Orthologs
Paralogs
Pathways/Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Publicationsfor IRGQ gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 UniProtKB/TrEMBL , and/or
7 Novoseek )
About This Section 9 PubMed articles for IRGQ gene integrated from 7 sources : (articles sorted by number of sources associating them with IRGQ) Association between genetic variants in VEGF, ERCC3 a nd occupational benzene haematotoxicity. (PubMed id 19773279) 1 Hosgood H.D....Lan Q. (2009) A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648) 2 Dephoure N.... Gygi S.P. (2008) Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931) 1 Ewing R.M.... Figeys D. (2007) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 2 Gerhard D.S....Malek J. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 Ota T.... Sugano S. (2004) Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197) 1 Brandenberger R.... Stanton L.W. (2004) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002) Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id ) 2 Aoki H.... Hino O. (2000) Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548) 1 Bonaldo M.F.... Soares M.B. (1996)
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Genomic Views
Intellectual Property
Medical News
Orthologs
Paralogs
Pathways/Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
External Searches for IRGQ gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Genomic Views
Intellectual Property
Medical News
Orthologs
Paralogs
Pathways/Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Genome Databases showing IRGQ gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Genomic Views
Intellectual Property
Medical News
Orthologs
Paralogs
Pathways/Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Other Databases showing IRGQ gene
(According to HUGE )
About This Section --
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Genomic Views
Intellectual Property
Medical News
Orthologs
Paralogs
Pathways/Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Specialized Databases showing IRGQ gene (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Genomic Views
Intellectual Property
Medical News
Orthologs
Paralogs
Pathways/Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
About This Section Patent Information for IRGQ gene: Search GeneIP for patents involving IRGQ GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
Jump to Section...
Aliases
Databases
Disorders
Domains/Families
Drugs/Compounds
Expression
Function
Genomic Views
Intellectual Property
Medical News
Orthologs
Paralogs
Pathways/Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Productsfor IRGQ gene (Antibodies, recombinant proteins, and assays by Millipore , Sigma-Aldrich , R&D Systems , Qiagen , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Epitomics , ProSpec , Uscn , Clones available from Millipore , Sigma-Aldrich , OriGene , GenScript , Sino Biological , PCR Arrays from SABiosciences , Drugs and/or compounds by Sigma-Aldrich , Tocris Bioscience , and/or
Enzo Life Sciences )About This Section
Search Tocris compounds for IRGQ
ELISAs and CLIAs for IRGQ
Jump to Section...
Aliases for IRGQ
Databases for IRGQ
Disorders for IRGQ
Domains/Families for IRGQ
Drugs/Compounds for IRGQ
Expression for IRGQ
Function for IRGQ
Genomic Views for IRGQ
Intellectual Property for IRGQ
Medical News for IRGQ
Orthologs for IRGQ
Paralogs for IRGQ
Pathways/Interactions for IRGQ
Products for IRGQ
Proteins for IRGQ
Publications for IRGQ
Search Box for IRGQ
Summaries for IRGQ
Transcripts for IRGQ
Variants for IRGQ
TOP
BOTTOM