Aliases &
Descriptions
for KIAA0528 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| KIAA05281 2 | | hypothetical protein LOC98472 | | DKFZp779N20442 |
Export aliases for KIAA0528 gene to outside databasesPrevious GC identifers: GC12M022949 GC12M022613 GC12M022501 GC12M022492 |
Summaries
for KIAA0528 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for KIAA0528 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KIAA0528 gene promoter:
oct-B2 POU2F2C POU2F2B POU2F2 (Oct-2.1) POU2F2 POU2F1 oct-B3 Oct-B1 FOXD3 Chx10
Other transcription factors
Search SABiosciences Chromatin IP Primers for KIAA0528
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for KIAA0528  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12p12.1 Ensembl cytogenetic band: 12p12.1 HGNC cytogenetic band: 12p12.1KIAA0528 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12M022367: view genomic region
(about GC identifiers)
Start:
|
22,367,856 bp from pter |
End:
|
22,463,789 bp from pter |
Size:
|
95,934 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr12- 22,601,541-22,697,452 |
RefSeq DNA sequence:- NC_000012.11 NT_009714.17
|
Proteins
for KIAA0528 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: K0528_HUMAN, Q86YS7 (See
protein sequence)Recommended Name: Uncharacterized protein KIAA0528 Size: 1000 amino acids; 110447 Da
Sequence caution: Sequence=BAA25454.3; Type=Erroneous initiation;
Secondary accessions: O60280 Q17RY7 Q7Z619 Q86SU3Alternative splicing: 2 isoforms: Q86YS7-1 Q86YS7-2 Explore the universe of human proteins at neXtProt for KIAA0528: NX_Q86YS7
Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_055617.1
ENSEMBL proteins: ENSP00000334229 ENSP00000388756 ENSP00000379345
Human Recombinant Proteins
Antibodies for KIAA0528:
Assays for KIAA0528: |
Protein
Domains/
Families
for KIAA0528 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KIAA0528 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q86YS7ProtoNet protein and cluster: Q86YS7 1 Blocks protein family: IPB000008 C2 domain
UniProtKB/Swiss-Prot: K0528_HUMAN, Q86YS7Similarity: Contains 1 C2 domain |
Gene Function
for KIAA0528 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
1 Gene Ontology (GO) molecular function term (GO ID links to tree view): About this table
KIAA0528 for ontologies About GeneDecksing
|
Pathways & Interactions
for KIAA0528 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for KIAA0528
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KIAA0528
1 Interacting protein for KIAA0528 (Q86YS71) via UniProtKB, MINT, and/or STRINGAbout this table
|
Drugs & Compounds
for KIAA0528 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for KIAA0528
|
Transcripts
for KIAA0528 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for KIAA0528 gene: NM_014802.1 Additional cDNA sequence: AB011100.3 AK295862.1 AK299353.1 AK310753.1 AY166851.1 BC042498.1 BC053885.1 BC117143.1 BC143859.1 BC143860.1 BC143878.1 BX537485.1 BX648560.1 12 DOTS entries: DT.100023388 DT.97838851 DT.315784 DT.91977055 DT.97789354 DT.121123033 DT.40290663 DT.121123114 DT.315785 DT.100724888 DT.100758208 DT.99932862 24/140 AceView cDNA sequences (see all 140): AA423900 BE674003 AW105708 BQ025509 BE550325 BE503018 AI683336 Z45275 NM_014802 AA446568 BC053885 AW590675 AW510321 BF793979 BQ946084 CD723648 AW007312 AI422576 BC042498 AI357418 AI636086 AI004954 N66211 AU132889
 highest scoring ESTs for KIAA0528:AA262674 AB011100 AL135274 AY166851 BQ220924 BQ929456 CF995059 AA037492 AA130663 AA130684 Unigene Cluster for KIAA0528: KIAA0528 Hs.271014 [show with all ESTs]Unigene Representative Sequence: BX537485
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for KIAA0528 (see all 8)
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14a | · | 14b | ^ | 15a | · | 15b | ^ | 16 | ^ | 17 | ^ |
|---|
|
| SP1: | | | | | | | - | | | | | | | | | | | | | | | | | | - | | | | | | | | - | | - | | | | | | | | | | | | - | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25 | ^ | 26 | ^ | 27 | ^ | 28 |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for KIAA0528
3 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000333957(uc010sir.1 uc010sis.1 uc001rfq.2 uc010sit.1 uc010siu.1 uc001rfr.2)
ENST00000446597 ENST00000396028(uc009ziy.1)
|
Expression
for KIAA0528 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| KIAA0528 expression in normal and diseased human tissues
1 / 2 / 3 4 probe-sets matching KIAA0528 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 42953_s_at2, 3
|
U95-B |
1 |
1.00 |
1.00 |
0.88 |
0.48 |
AA279214 |
0.60 |
1.00 |
0.82 |
1 |
| 35252_at2, 3
|
U95-A |
1 |
0.75 |
1.00 |
0.62 |
1.56 |
AB011100 |
0.80 |
1.00 |
0.91 |
1 |
| 212943_at2, 3
|
U133-A |
1 |
0.73 |
1.00 |
-- |
-- |
AB011100 |
0.80 |
1.00 |
0.91 |
1 |
| 212943_at2
|
U133Plus2 |
1 |
0.73 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
KIAA0528 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: AGAATTTTCT
SOURCE GeneReport for Unigene cluster: Hs.271014
Expression variation in blood from EXPOLDB for KIAA0528 SABiosciences Custom PCR Arrays for KIAA0528
|
Orthologs
for KIAA0528 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for KIAA0528 gene from 5/10 species (see all 10)
About this table Species with no ortholog for KIAA0528
ENSEMBL Gene Tree for KIAA0528 (if available) |
Paralogs
for KIAA0528 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| -- |
Genomic Variants
for KIAA0528 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 12 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for KIAA0528 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for KIAA0528
1 CNV: 3880 | | QIAGEN SeqTarget long-range PCR primers for resequencing KIAA0528 |
|
Disorders & Mutations
for KIAA0528 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Medical News
for KIAA0528 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for KIAA0528 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
10/12 PubMed articles for KIAA0528 gene, integrated from 7 sources (see all 12):
(articles sorted by number of sources associating them with KIAA0528)- Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9628581)1, 2, 3 Nagase T....Ohara O. (1998)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (2009)
- Large-scale proteomics analysis of the human kinome. (PubMed id 19369195)2 Oppermann F.S.... Daub H. (2009)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)2 Cantin G.T....Yates J.R. III (2008)
- Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)2 Daub H.... Mann M. (2008)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
- Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931)1 Ewing R.M.... Figeys D. (2007)
|
External Searches for KIAA0528 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing KIAA0528 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KIAA0528 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing KIAA0528 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for KIAA0528 gene:
Search GeneIP for patents involving KIAA0528
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KIAA0528 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
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