Aliases &
Descriptions
for KIAA1486 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| KIAA14861 2 | | hypothetical protein LOC576242 |
Export aliases for KIAA1486 gene to outside databasesPrevious GC identifers: GC02P224287 GC02P224986 GC02P226229 GC02P226468 GC02P226091 GC02P225973 |
Summaries
for KIAA1486 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for KIAA1486 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KIAA1486 gene promoter:
SRF Pax-2 MEF-2A STAT5A Nkx3-1 Nkx3-1 v1 Nkx3-1 v2 Nkx3-1 v3 Nkx3-1 v4 FOXO3a
Other transcription factors
Search SABiosciences Chromatin IP Primers for KIAA1486
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q36.3 Ensembl cytogenetic band: 2q36.3 HGNC cytogenetic band: 2q36.3KIAA1486 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P218366: view genomic region
(about GC identifiers)
Start:
|
218,366,411 bp from pter |
End:
|
218,369,002 bp from pter |
Size:
|
2,592 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr2+ 226,265,364-226,518,734 |
RefSeq DNA sequence:- NC_000002.11 NT_005403.17
|
Proteins
for KIAA1486 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
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|
UniProtKB/Swiss-Prot: K1486_HUMAN, Q9P242 (See
protein sequence)Recommended Name: Uncharacterized protein KIAA1486 Size: 653 amino acids; 70548 Da
Sequence caution: Sequence=BAA96010.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A2RRN4 Q96NL2Alternative splicing: 3 isoforms: Q9P242-1 Q9P242-2 Q9P242-3 Explore the universe of human proteins at neXtProt for KIAA1486: NX_Q9P242
Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_065915.1
ENSEMBL proteins: ENSP00000272907 ENSP00000386437
Human Recombinant Proteins
Antibodies for KIAA1486:
Assays for KIAA1486: |
Protein
Domains/
Families
for KIAA1486 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q9P242 |
Gene Function
for KIAA1486 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
|
Pathways & Interactions
for KIAA1486 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for KIAA1486
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KIAA1486
|
Drugs & Compounds
for KIAA1486 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for KIAA1486
|
Transcripts
for KIAA1486 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for KIAA1486 gene: NM_020864.1 Additional cDNA sequence: AB040919.1 AK055226.1 BC131727.1 3 DOTS entries: DT.120955947 DT.70103142 DT.97799197 8 AceView cDNA sequences: BI828006 AK055226 AB040919 AI825640 AI825189 C15204 BQ338801 AW235426
 highest scoring ESTs for KIAA1486:AB040919 AI825189 AK055226 AI825640 BI828006 BQ338801 C15204 AI540642 AW235426 XM_041126 Unigene Cluster for KIAA1486: KIAA1486 Hs.224409 [show with all ESTs]Unigene Representative Sequence: NM_020864
GeneLoc Exon Structure
2 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000272907(uc002voe.2 uc010fxa.1 uc002vof.1) ENST00000409269
|
Expression
for KIAA1486 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| KIAA1486 expression in normal and diseased human tissues
1 / 2 / 3 3 probe-sets matching KIAA1486 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 70668_at2, 3
|
U95-D |
1 |
0.62 |
1.00 |
1.00 |
1.00 |
AI825189 |
0.80 |
1.00 |
0.91 |
1 |
| 233916_at2, 3
|
U133-B |
1 |
0.82 |
1.00 |
-- |
-- |
AB040919 |
0.80 |
1.00 |
0.91 |
1 |
| 233916_at2
|
U133Plus2 |
1 |
0.82 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
KIAA1486 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: CATTCCTATA
SOURCE GeneReport for Unigene cluster: Hs.224409
SABiosciences Custom PCR Arrays for KIAA1486
|
Orthologs
for KIAA1486 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for KIAA1486 gene from 5/6 species (see all 6)
About this table Species with no ortholog for KIAA1486
ENSEMBL Gene Tree for KIAA1486 (if available) |
Paralogs
for KIAA1486 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for KIAA1486 gene
- C7orf512
KIAA1486 for paralogs About GeneDecksing
|
Genomic Variants
for KIAA1486 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 2 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for KIAA1486 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for KIAA1486
3 CNVs: 78990 90307 63313 | | QIAGEN SeqTarget long-range PCR primers for resequencing KIAA1486 |
|
Disorders & Mutations
for KIAA1486 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KIAA1486 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: KIAA1486 (2 documents)
Export disorders and mutations for KIAA1486 gene to outside databases
|
Medical News
for KIAA1486 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for KIAA1486 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
10 PubMed articles for KIAA1486 gene integrated from 7 sources:
(articles sorted by number of sources associating them with KIAA1486)- Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)1, 2, 3 Nagase T.... Ohara O. (2000)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide pol ymorphisms. (PubMed id 20889853)1 de Miguel-Yanes J.M....Meigs J.B. (2010 Oct 1)
- Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)2 Cantin G.T....Yates J.R. III (2008)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for KIAA1486 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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|
|
Genome Databases showing KIAA1486 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KIAA1486 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing KIAA1486 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for KIAA1486 gene:
Search GeneIP for patents involving KIAA1486
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KIAA1486 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
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