Aliases & Descriptions for KIF19 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases & Descriptions |
|---|
| kinesin family member 191 2 | | KIF19A1 2 | | FLJ373001 2 | | kinesin-like protein KIF192 |
Export aliases for KIF19 gene to outside databasesPrevious GC identifer: GC17P069834 |
Summaries for KIF19 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| -- |
Genomic Views for KIF19 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences) About This Section
| Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the KIF19 gene promoter: CUTL1 STAT5A Max1 c-Myc Pax-2 GR-alpha GR-beta deltaCREB CREB NF-kappaB1 Other transcription factors
Search SABiosciences Chromatin IP Primers for KIF19
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for KIF19  |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q25.1 Ensembl cytogenetic band: 17q25.1 HGNC cytogenetic band: 17q25KIF19 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P072321: view genomic region
(about GC identifiers)
Start:
|
72,321,951 bp from pter |
End:
|
72,371,096 bp from pter |
Size:
|
49,146 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr17+ 67,732,034-67,761,658 |
RefSeq DNA sequence:- NC_000017.10 NT_010783.15
|
Proteins for KIF19 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
| UniProtKB/Swiss-Prot: KIF19_HUMAN, Q2TAC6 (See
protein sequence)Recommended Name: Kinesin-like protein KIF19 Size: 998 amino acids; 111332 Da
Secondary accessions: A6NLG2 B7ZKR1 Q52M87 Q8N1X8 Q8TAB6Alternative splicing: 3 isoforms: Q2TAC6-1 Q2TAC6-2 Q2TAC6-3 Explore the universe of human proteins at neXtProt for KIF19: NX_Q2TAC6 
REFSEQ proteins: NP_694941.2
ENSEMBL proteins: ENSP00000374566 ENSP00000414666 ENSP00000374567 ENSP00000353021 ENSP00000335158
Human Recombinant Proteins
3 Gene Ontology (GO) cellular component terms (GO ID links to tree view): About this table
KIF19 for ontologies About GeneDecksing
Antibodies for KIF19: Assays for KIF19: |
Protein
Domains/ Families for KIF19 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KIF19 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q2TAC6ProtoNet protein and cluster: Q2TAC6 UniProtKB/Swiss-Prot: KIF19_HUMAN, Q2TAC6Similarity: Belongs to the kinesin-like protein familySimilarity: Contains 1 kinesin-motor domain |
Gene Function for KIF19 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
5/6 Gene Ontology (GO) molecular function terms (GO ID links to tree view) (see all 6): About this table
KIF19 for ontologies About GeneDecksing
|
Pathways & Interactions for KIF19 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
| SABiosciences Custom Pathway-Focused PCR Arrays for KIF19 
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KIF19
2 Gene Ontology (GO) biological process terms (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007018 | microtubule-based movement |
IEA | -- | | GO:0007186 | G-protein coupled receptor protein signaling pathway |
-- | -- | About this table
KIF19 for ontologies About GeneDecksing
|
Drugs & Compounds for KIF19 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for KIF19
|
Transcripts for KIF19 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences) About This Section
|
REFSEQ mRNAs for KIF19 gene: NM_153209.3 Additional cDNA sequence: AK094619.1 BC067749.1 BC093631.1 BC104852.1 BC110989.1 BC143327.1 6 DOTS entries: DT.65287915 DT.100016524 DT.99932766 DT.102820343 DT.91791104 DT.40214064 15 AceView cDNA sequences: BG713907 CB134958 CD672631 CD517210 CD518240 BC067749 NM_153209 BC026362 BI833383 AK094619 BU150146 AX746676 BI772188 AK090911 BI544532
highest scoring ESTs for KIF19:AK094619 BC026362 BC093631 BG713907 BI772188 BI833383 BU150146 CD517210 NM_153209 AI560769 Unigene Cluster for KIF19: Kinesin family member 19 Hs.372773 [show with all ESTs]Unigene Representative Sequence: NM_153209
GeneLoc Exon Structure
5 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000389916(uc002jkl.2 uc002jkm.3) ENST00000440684 ENST00000389917(uc002jkj.2) ENST00000359939(uc002jkk.2) ENST00000335666(uc010wqx.1 uc010wqy.1)
|
Expression for KIF19 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| KIF19 expression in normal and diseased human tissues
1 / 2 / 3 4 probe-sets matching KIF19 gene
Affymetrix probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 74496_at2, 3
|
U95-D |
1 |
0.44 |
1.00 |
0.83 |
1.00 |
AW014742 |
0.20 |
1.00 |
0.72 |
1 |
| 73434_at2, 3
|
U95-D |
1 |
0.38 |
1.00 |
0.73 |
1.28 |
AI560769 |
0.40 |
1.00 |
0.76 |
1 |
| 87629_at*2
|
U95-E |
6 |
0.31 |
0.17 |
0.30 |
0.73 |
-- |
-- |
-- |
-- |
-- |
| 1553314_a_at2
|
U133Plus2 |
1 |
0.64 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
KIF19 for expression About GeneDecksing
Data from
Genenote 
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: GCCAGGACGG
SOURCE GeneReport for Unigene cluster: Hs.372773 SABiosciences Custom PCR Arrays for KIF19 
|
Orthologs for KIF19 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for KIF19 gene from 5/9 species (see all 9)
About this table Species with no ortholog for KIF19
ENSEMBL Gene Tree for KIF19 (if available) |
Paralogs for KIF19 gene(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Paralogs for KIF19 gene
- GPR1392
KIF19 for paralogs About GeneDecksing
|
Genomic Variants for KIF19 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 17 pos | Sequence | Recs | AA Chg | Type | More | Recs | Allele freq | Pop | Total sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for KIF19 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 8 variations for KIF19 8 CNVs: 34522 53066 5336 67262 7171 8852 39209 5029 |  | QIAGEN SeqTarget long-range PCR primers for resequencing KIF19  |
|
Disorders & Mutations for KIF19 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KIF19 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: KIF19 (1 document) Export disorders and mutations for KIF19 gene to outside databases
|
Medical News for KIF19 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for KIF19 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
| 7 PubMed articles for KIF19 gene integrated from 7 sources: (articles sorted by number of sources associating them with KIF19)- DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)1, 2 Zody M.C.... Nusbaum C. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- All kinesin superfamily protein, KIF, genes in mouse and human. (PubMed id 11416179)1, 3 Miki H....Hirokawa N. (2001)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for KIF19 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing KIF19 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KIF19 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing KIF19 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
|
About This Section
| Patent Information for KIF19 gene: Search GeneIP for patents involving KIF19
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for KIF19 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn, Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences) About This Section
|
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