Aliases &
Descriptions
for KIF25 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| kinesin family member 251 2 | | MGC1633612 | | KNSL32 3 5 | | OTTHUMP000002190772 | | kinesin-like 31 2 | | kinesin-like protein KIF252 | | Kinesin-like protein 32 3 | | |
Export aliases for KIF25 gene to outside databasesPrevious GC identifers: GC06P168140 GC06P168176 GC06P168177 GC06P168237 GC06P168161 GC06P168418 |
Summaries
for KIF25 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for KIF25:
The protein encoded by this gene is a member of the kinesin-like protein family. Protein family members aremicrotubule-dependent molecular motors that transport organelles within cells and move chromosomes during celldivision. However, the particular function of this gene product has not yet been determined. Two alternatively splicedtranscript variants which encode products have been described. Other splice variants have been found that lack exon 2and the initiation codon for translation. (provided by RefSeq)
|
Genomic Views
for KIF25 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for KIF25
Other transcription factors
Search SABiosciences Chromatin IP Primers for KIF25
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6q27 Ensembl cytogenetic band: 6q27 HGNC cytogenetic band: 6q27KIF25 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P165847: view genomic region
(about GC identifiers)
Start:
|
165,847,953 bp from pter |
End:
|
165,875,245 bp from pter |
Size:
|
27,293 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr6+ 168,396,921-168,445,769 |
RefSeq DNA sequence:- NC_000006.11 NT_025741.15
|
Proteins
for KIF25 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: KIF25_HUMAN, Q9UIL4 (See
protein sequence)Recommended Name: Kinesin-like protein KIF25 Size: 384 amino acids; 40686 Da
Secondary accessions: O94775 Q5SZU9Alternative splicing: 2 isoforms: Q9UIL4-1 Q9UIL4-2 Explore the universe of human proteins at neXtProt for KIF25: NX_Q9UIL4
REFSEQ proteins (2 alternative transcripts):
NP_005346.3 NP_085118.2
ENSEMBL proteins: ENSP00000388878 ENSP00000346401 ENSP00000252688 ENSP00000427464
Human Recombinant Proteins
2 Gene Ontology (GO) cellular component terms (GO ID links to tree view): About this table
KIF25 for ontologies About GeneDecksing
Antibodies for KIF25:
Assays for KIF25: |
Protein
Domains/
Families
for KIF25 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KIF25 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UIL4ProtoNet protein and cluster: Q9UIL4 UniProtKB/Swiss-Prot: KIF25_HUMAN, Q9UIL4Similarity: Belongs to the kinesin-like protein familySimilarity: Contains 1 kinesin-motor domain |
Gene Function
for KIF25 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
4 Gene Ontology (GO) molecular function terms (GO ID links to tree view): About this table
KIF25 for ontologies About GeneDecksing
|
Pathways & Interactions
for KIF25 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for KIF25
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KIF25
5/8 Interacting proteins for KIF25 (ENSP000003464013) via UniProtKB, MINT, and/or STRING (see all 8)About this table
3 Gene Ontology (GO) biological process terms (GO ID links to tree view): About this table
KIF25 for ontologies About GeneDecksing
|
Drugs & Compounds
for KIF25 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for KIF25
|
Transcripts
for KIF25 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for KIF25 gene (2 alternative transcripts): NM_005355.3 NM_030615.2 Additional cDNA sequence: AB012722.2 AK289488.1 5 DOTS entries: DT.92072033 DT.121396396 DT.95174531 DT.121396402 DT.70102980 8 AceView cDNA sequences: NM_030615 BX110428 AB012722 NM_005355 AW629125 AI291787 AW243854 BF943522
 highest scoring ESTs for KIF25:AB012722 AW629125 BF943522 NM_005355 NM_030615 AI291787 AW243854 BC130489 BX110428 DB341586 Unigene Cluster for KIF25: Kinesin family member 25 Hs.150013 [show with all ESTs]Unigene Representative Sequence: AK289488
GeneLoc Exon Structure
6 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000515361 ENST00000443060(uc010kkt.1) ENST00000354419(uc003qwk.1 uc003qwl.1)
ENST00000351261 ENST00000504593 ENST00000496008
|
Expression
for KIF25 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| KIF25 expression in normal and diseased human tissues
1 / 2 / 3 5 probe-sets matching KIF25 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 31978_at2, 3
|
U95-A |
1 |
0.81 |
1.00 |
1.00 |
1.00 |
AB012722 |
1.00 |
1.00 |
1.00 |
1 |
| 207682_s_at2, 3
|
U133-A |
1 |
0.91 |
1.00 |
-- |
-- |
NM_005355 |
0.60 |
1.00 |
0.82 |
1 |
| 208128_x_at2, 3
|
U133-A |
1 |
0.82 |
1.00 |
-- |
-- |
NM_030615 |
0.60 |
1.00 |
0.82 |
1 |
| 207682_s_at2
|
U133Plus2 |
1 |
0.91 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 208128_x_at2
|
U133Plus2 |
1 |
0.82 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
KIF25 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: CGGAGCAGGT
SOURCE GeneReport for Unigene cluster: Hs.150013
Expression variation in blood from EXPOLDB for KIF25 SABiosciences Custom PCR Arrays for KIF25
|
Orthologs
for KIF25 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for KIF25 gene from 2 species
About this table Species with no ortholog for KIF25
ENSEMBL Gene Tree for KIF25 (if available) |
Paralogs
for KIF25 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for KIF25 gene
- KIFC22 KIFC32 KIFC12
KIF25 for paralogs About GeneDecksing
|
Genomic Variants
for KIF25 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 6 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for KIF25 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 24 variations for KIF25
15/24 CNVs (see all 24): 31312 5231 34566 8540 5229 51850 51849 5234 53975 5235 8541 2667 34495 5233 7547 | | QIAGEN SeqTarget long-range PCR primers for resequencing KIF25 |
|
Disorders & Mutations
for KIF25 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KIF25 for disorders About GeneDecksing
OMIM: 603815
Export disorders and mutations for KIF25 gene to outside databases
|
Medical News
for KIF25 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for KIF25 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
7 PubMed articles for KIF25 gene integrated from 7 sources:
(articles sorted by number of sources associating them with KIF25)- Identification, genomic organization, and alternative splicing of KNSL3, a novel human gene encoding a kinesin-like protein. (PubMed id 9925916)1, 2, 7 Okamoto S.... Nakamura Y. (1998)
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
- Assignment1 of CSRP1 encoding the LIM domain protein CRP1, to human chromosome 1q32 by fluorescence in situ hybridization. (PubMed id 9925910)1, 3 Erdel M. and Weiskirchen R. (1998)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- All kinesin superfamily protein, KIF, genes in mouse and human. (PubMed id 11416179)1 Miki H....Hirokawa N. (2001)
- The roles of microtubule-based motor proteins in mitosis: comprehensive RNAi analysis in the Drosophila S2 cell line. (PubMed id 12975346)7 Goshima G. and Vale R.D. (2003)
- Heterotrimeric kinesin II is the microtubule motor protein responsible for pigment dispersion in Xenopus melanophores. (PubMed id 9852150)7 Tuma M.C....Gelfand V. (1998)
|
External Searches for KIF25 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing KIF25 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KIF25 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing KIF25 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for KIF25 gene:
Search GeneIP for patents involving KIF25
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KIF25 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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| |  | Search Tocris compounds for KIF25 |
| |  |  |  |  | | | | |
 | | | ELISAs and CLIAs for KIF25 |
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