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KLK13 Gene

protein-coding   GIFtS: 58

GC19M047892
kallikrein-related peptidase 13
(Previous name: kallikrein 13 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
kallikrein-related peptidase 131 2     kallikrein-132
KLK-L41 2 3     DKFZp586J19232
KLKL42 3 5     kallikrein-like gene 42
kallikrein 131 2     EC 3.4.21.-3
Kallikrein-like protein 42 3     

External Ids:    HGNC: 63611   Entrez Gene: 260852   Ensembl: ENSG000001677597   UniProtKB: Q9UKR33   

Export aliases for KLK13 gene to outside databases

Previous GC identifers: GC19M052189 GC19M051920 GC19M056235 GC19M056251 GC19M051559


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for KLK13:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that
many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease
biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19.
Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An
additional transcript variant has been identified, but its full length sequence has not been determined. (provided by
RefSeq)

Gene Wiki entry for KLK13

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KLK13 gene promoter:
         GCNF-2   GCNF-1   NF-E2   NF-E2 p45   Bach2   MyoD   AP-1   c-Fos   c-Jun   Fra-1   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for KLK13

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.33   Ensembl cytogenetic band:  19q13.41   HGNC cytogenetic band: 19q13.33

KLK13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KLK13 gene location

GeneLoc gene densities for chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M047892:  view genomic region     (about GC identifiers)

Start:
47,892,411 bp from pter
End:
47,901,418 bp from pter
Size:
9,008 bases
Orientation:
minus strand

1 alternative location:
Chr19- 51,559,463-51,568,367     
RefSeq DNA sequence:
NC_000019.9  NT_011109.16  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: KLK13_HUMAN, Q9UKR3 (See protein sequence)
Recommended Name: Kallikrein-13 precursor  
Size: 277 amino acids; 30570 Da
Subcellular location: Secreted (Probable)
Secondary accessions: A7UNK6 Q9Y433

Explore the universe of human proteins at neXtProt for KLK13: NX_Q9UKR3 

REFSEQ proteins: NP_056411.1  

ENSEMBL proteins: 
ENSP00000156476 ENSP00000365995 ENSP00000334079 ENSP00000392640 ENSP00000365997 


Human Recombinant Proteins 
Browse Purified and Recombinant Proteins at Millipore
Browse Human Recombinant Proteins at Sigma-Aldrich
R&D Systems Recombinant & Natural Proteins for KLK13 (Kallikrein 13)
Browse recombinant and purified proteins available from Enzo Life Sciences
Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
OriGene Protein Over-expression Lysate: KLK13
GenScript Custom Purified and Recombinant Proteins Services for KLK13 
Novus Biologicals Proteins for KLK13
Novus Biologicals Lysates for KLK13
Sino Biological Recombinant Protein for KLK13
Browse ProSpec Recombinant Proteins

4 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005576 extracellular region TAS10766816
GO:0005615 extracellular space IEA--
GO:0005737 cytoplasm IDA12642628
GO:0030141 stored secretory granule IEA--
About this table

KLK13 for ontologies           About GeneDecksing



Antibodies for KLK13: 
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Sigma-Aldrich Antibodies for KLK13
R&D Systems Antibodies for KLK13 (Kallikrein 13)
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GenScript Custom Superior Antibodies Services for KLK13 
Novus Biologicals Antibodies for KLK13
Browse antibodies at Epitomics

Assays for KLK13: 
Browse Kits and Assays available from Millipore
Browse ELISAs at Sigma-Aldrich
OriGene Custom Immunoassay Development 
Browse OriGene Fluorogenic Cell Assay Kits 
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for KLK13 
Browse Enzo Life Sciences for kits & assays
Uscn ELISAs and CLIAs for KLK13 


(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

KLK13 for domains           About GeneDecksing

4 InterPro domains/families:
 IPR001314 Peptidase_S1A
 IPR001254 Peptidase_S1_S6
 IPR018114 Peptidase_S1/S6_AS
 IPR009003 Ser/Cys_Pept_Trypsin-like

Graphical View of Domain Structure for InterPro Entry Q9UKR3

ProtoNet protein and cluster: Q9UKR3

2 Blocks protein families:
IPB001254 Serine protease
IPB001314 Chymotrypsin serine protease family (S1) signature


UniProtKB/Swiss-Prot: KLK13_HUMAN, Q9UKR3
Similarity: Belongs to the peptidase S1 family. Kallikrein subfamily
Similarity: Contains 1 peptidase S1 domain


(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

Inhib.
RNA:
    
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich siRNA Panels and siRNA for KLK13
Sigma-Aldrich shRNA for KLK13
OriGene 29mer shRNA kits in GFP-retroviral vector: KLK13
OriGene shRNA RFP: KLK13
OriGene basic RS shRNA: KLK13
OriGene siRNA: KLK13
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of KLK13 
miRNA:Sigma-Aldrich microRNA Mimics for KLK13
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of KLK13 
Search SABiosciences for Assays for microRNAs that regulate KLK13

Gene
Editing:
Browse CompoZr Knockout ZFN at Sigma-Aldrich 

Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
Browse iPSC Reprogramming Factors at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: KLK13
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: KLK13
OriGene untagged cDNA clones in CMV expression vector: KLK13
Browse 3'-UTR reporter clones for miRNA target validation 
Browse MicroRNA Expression Plasmids 
GenScript cDNA clone with any tag delivered in your preferred vector: KLK13 
Sino Biological Human cDNA Clone for KLK13

Cell
Lines:
  
GenScript Custom overexpressing Cell Line Services for KLK13 

5/6 Gene Ontology (GO) molecular function terms (GO ID links to tree view) (see all 6):

GO IDQualified GO termEvidencePubMed IDs
GO:0003824 catalytic activity ----
GO:0004175 endopeptidase activity ----
GO:0004252 serine-type endopeptidase activity NAS10766816
GO:0005515 protein binding IPI14687906
GO:0008233 peptidase activity IEA--
About this table

KLK13 for ontologies           About GeneDecksing


(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section

    SABiosciences Custom Pathway-Focused PCR Arrays for KLK13 

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KLK13

2 Gene Ontology (GO) biological process terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0006508 proteolysis NAS10766816
GO:0016485 protein processing IEA--
About this table

KLK13 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

KLK13 for compounds           About GeneDecksing

Browse Small Molecules at Sigma-Aldrich
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for KLK13
2 Novoseek chemical compound relationships for KLK13 gene
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
serine 56.1 3 15381110 (1), 14966091 (1), 14687906 (1)
steroid 35.5 1 14966091 (1)
About this table



(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib.
RNA:
     
Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich siRNA Panels and siRNA for KLK13
Sigma-Aldrich shRNA for KLK13
OriGene 29mer shRNA kits in GFP-retroviral vector: KLK13
OriGene shRNA RFP: KLK13
OriGene basic RS shRNA: KLK13
OriGene siRNA: KLK13
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of KLK13 
miRNA: Sigma-Aldrich microRNA Mimics for KLK13
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of KLK13 
Search SABiosciences for Assays for microRNAs that regulate KLK13
Clones: Browse FLAG tag genes at Sigma-Aldrich
OriGene GFP tagged cDNA clones in CMV expression vector: KLK13
OriGene Myc/DDK tagged cDNA clones in CMV expression vector: KLK13
OriGene untagged cDNA clones in CMV expression vector: KLK13
Browse 3'-UTR reporter clones for miRNA target validation 
Browse OriGene MicroRNA Expression Plasmids 
GenScript cDNA clone with any tag delivered in your preferred vector: KLK13 
Primers: OriGene genome-wide validated SYBR primer pairs: KLK13
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for KLK13: PPH06142A

REFSEQ mRNAs for KLK13 gene: 

NM_015596.1  

Additional cDNA sequence: 

AB108823.1 AB108824.1 AB451465.1 AL050220.1 AY923171.1 AY923172.1 AY923173.1 AY923174.1 
AY923175.1 BC069334.1 BC069543.1 

6 DOTS entries:

DT.100741572  DT.65285181  DT.92422253  DT.121487859  DT.121487868  DT.99996047 

24/25 AceView cDNA sequences (see all 25):

AB108823 AB108824 NM_015596 AI889574 BX106071 AA846771 BQ027298 AA399955 
AL050220 BC069543 BC069334 AI002101 BE716310 AW243944 AI032327 BE716321 
AA401397 BE715189 BF354061 AW189585 BE184351 BF354651 BF354621 BQ356844 

highest scoring ESTs for KLK13:

AL050220 BC069334 BC069543 AA401397 AB108823 AB108824 AI032327 AW243944 AY923171 AY923172 

Unigene Cluster for KLK13:

Kallikrein-related peptidase 13
Hs.165296  [show with all ESTs]
Unigene Representative Sequence: AY923172


GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for KLK13 (see all 8)

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d ^ 6 ^ 7a · 7b · 7c
SP1:              -                             -     -                           
SP2:              -                                                               
SP3:              -     -                       -     -                           
SP4:              -     -                             -                           
SP5:              -     -                 -     -     -                           

About this scheme

ECgene alternative splicing isoforms for KLK13
5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000156476(uc002pvn.2 uc002pvo.2 uc002pvp.2 uc002pvq.2 uc002pvr.2)
ENST00000376799(uc010eon.2) ENST00000335422(uc010eoo.2) ENST00000441527(uc002pvl.2 uc002pvm.2)
ENST00000376801

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

KLK13 expression in normal and diseased human tissues

1  / 2  / 3

6 probe-sets matching KLK13 gene

Affymetrix
probe-set
Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
36406_at2, 3 U95-A 1 1.00 1.00 0.58 0.86 AA401397 0.60 1.00 0.82 1
36407_at2, 3 U95-A 1 0.81 1.00 0.82 1.14 AL050220 1.00 1.00 1.00 1
205783_at2, 3 U133-A 1 1.00 1.00 -- -- NM_015596 0.60 1.00 0.82 1
217315_s_at2, 3 U133-A 1 0.55 1.00 -- -- AL050220 1.00 1.00 1.00 1
205783_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
217315_s_at2 U133Plus2 1 0.55 1.00 -- -- -- -- -- -- --
About this table

KLK13 for expression           About GeneDecksing

Data from Genenote  (Publications) and GNF BioGPS
    About these images
KLK13 gene expression
KLK13 gene electronic northern expression
KLK13 gene sage expression
About these images

CGAP SAGE TAG: TGGGCAACCT

SOURCE GeneReport for Unigene cluster: Hs.165296

Expression variation in blood from EXPOLDB for KLK13

UniProtKB/Swiss-Prot: KLK13_HUMAN, Q9UKR3
Tissue specificity: Expressed in prostate, breast, testis and salivary gland

Primers: OriGene genome-wide validated SYBR primer pairs: KLK13
Browse OriGene validated miRNA SYBR primer pairs 
SABiosciences RT2 qPCR Primer Assay for KLK13: PPH06142A
    SABiosciences Custom PCR Arrays for KLK13 


(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for KLK13 gene from 5/6 species (see all 6)
Organism Gene Locus Description Human
Similarity
NCBI accessions
dog
(Canis familiaris)
KLK131   -- kallikrein-related peptidase 13 86.4(n)
84.12(a)
484349  XM_541465.2  XP_541465.2 
chimpanzee
(Pan troglodytes)
KLK131   -- kallikrein-related peptidase 13 99.61(n)
100(a)
748200  XM_001160106.1  XP_001160106.1 
cow
(Bos taurus)
KLK131   -- kallikrein-related peptidase 13 82.06(n)
79.27(a)
540297  XM_593029.3  XP_593029.3 
rat
(Rattus norvegicus)
Klk131   -- kallikrein related-peptidase 13 78.67(n)
80(a)
292848  XM_218643.3  XP_218643.3 
mouse
(Mus musculus)
Klk131 , 5 7 (28.26 cM)5
kallikrein related-peptidase 131, 5 78.79(n)1
79.27(a)1
6268341  NM_001039042.21  NP_001034131.21 
 AY1524325  BC0637635  (see all 7)
About this table        Species with no ortholog for KLK13

ENSEMBL Gene Tree for KLK13 (if available)

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
Paralogs for KLK13 gene
KLK62  KLK122  KLK22  KLK102  KLK12  KLK152  KLK52  KLK42  
KLK112  KLK72  KLK82  KLK32  KLK92  

KLK13 for paralogs           About GeneDecksing



(SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

10/103 NCBI SNPs in KLK13 are shown (see all 103)
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidChr 19 posSequenceRecsAA
Chg
TypeMoreRecsAllele
freq
PopTotal
sample
More
----------
rs10806681,2
C,F,51566170(+) AGCTCA/CGTGGT 1 -- int112Minor allele frequency- C:0.06MN NS EA NA WA 1084
rs10806691,2
C,F,A,51566268(+) tcagaC/Tgctga 1 -- int113Minor allele frequency- T:0.13MN NS EA NA 1076
rs14043181,2
C,F,A,51566231(-) tcatcT/Cctcta 1 -- int113Minor allele frequency- C:0.39MN NS EA NA WA 716
rs14043191,2
C,F,A,51566197(-) ACCGAC/TAACTT 1 -- int129Minor allele frequency- T:0.33NS MN EA NA WA 1876
rs14043201,2
C,F,A,51566146(-) GCCCTG/ATAGTT 1 -- int19Minor allele frequency- A:0.29MN EA NS NA WA 632
rs18804131,2
C,F,O,A,H,51560467(+) CCCATT/CCATAT 1 -- int119Minor allele frequency- C:0.50NA EA NS WA 1389
rs25694741,2
C,F,O,A,H,51563965(+) GGGTCA/GGATTA 1 -- int124Minor allele frequency- G:0.16EA NA NS WA 1542
rs25694751,2
C,F,A,51565975(+) GAAAAG/AGTAAT 1 -- int125Minor allele frequency- A:0.32NS EA NA WA 1650
rs25694761,2
C,F,51569548(+) ACCACC/TGGACA 1 -- ng514Minor allele frequency- T:0.07NS EA 420
rs25694771,2
C,A,51570126(+) aacatA/Gtgtca 1 -- ng519Minor allele frequency- G:0.50NA EA WA 222
About this table

HapMap Linkage Disequilibrium images for KLK13 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for KLK13
     2 CNVs: 48034 58886

QIAGEN SeqTarget long-range PCR primers for resequencing KLK13 

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section

KLK13 for disorders           About GeneDecksing

OMIM: 605505

2 Novoseek disease relationships for KLK13 gene

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
ovarian cancer 36.7 1 15381110 (1)
breast cancer 33.5 6 10766816 (2), 11986781 (2), 14966091 (1)
About this table

Human Genome Epidemiology (HuGE) Navigator: KLK13 (1 document)

Export disorders and mutations for KLK13 gene to outside databases

(Possibly Related Articles in Doctor's Guide)
About This Section
  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
About This Section

10/25 PubMed articles for KLK13 gene, integrated from 7 sources (see all 25):
(articles sorted by number of sources associating them with KLK13)
  1. Identification and characterization of KLK-L4, a new kallikrein-like gene that appears to be down-regulated in breast cancer tissues. (PubMed id 10766816)1, 2, 7 Yousef G.M.... Diamandis E.P. (2000)
  2. Understanding the accuracy of statistical haplotype inference with sequence data of known phase. (PubMed id 17922479)1, 2 Andres A.M....Hixson J.E. (2007)
  3. Proceedings of the 1st International Symposium on Kallikreins, Lausanne, Switzerland, September 1-3 , 2005. (PubMed id 16800723)1, 3 (2006)
  4. A comprehensive nomenclature for serine proteases with homology to tissue kallikreins. (PubMed id 16800724)1, 3 Lundwall A....Yousef G.M. (2006)
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  6. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
  7. Human kallikrein gene 13 (KLK13) expression by quantitative RT-PCR: an independent indicator of favourable prognosis in breast cancer. (PubMed id 11986781)1, 7 Chang A....Diamandis E.P. (2002)
  8. Identification and molecular characterization of five novel kallikrein gene 13 (KLK13; KLK-L4) splice variants: differential expression in the human testis and testicular cancer. (PubMed id 11848466)1, 7 Chang A.... Diamandis E.P. (2001)
  9. Complex formation between human kallikrein 13 and serum protease inhibitors. (PubMed id 14687906)1, 7 Kapadia C....Diamandis E.P. (2004)
  10. Human kallikrein 13 involvement in extracellular matrix degradation. (PubMed id 15381110)1, 7 Kapadia C....Diamandis E.P. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Disorders
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 26085 HGNC: 6361 AceView: KLK13 Ensembl:ENSG00000167759 euGenes: HUgn26085
ECgene: KLK13 H-InvDB: KLK13

(According to HUGE)
About This Section
  --

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
ATLAS Chromosomes in Cancer entry for KLK13 Genetics and Cytogenetics in Oncology and Haematology

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from XenneX, Inc.)
About This Section
Patent Information for KLK13 gene:
Search GeneIP for patents involving KLK13

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
About This Section

 Millipore Custom Antibody & Bulk Services
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 Predesigned and custom siRNAs for KLK13 Antibodies for KLK13
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 "Your Favorite Gene" Pathways and Molecular Interaction Networks Browse Nano Scale siRNA at Sigma-Aldrich
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 Browse microRNA Target Validation Systems at Sigma-Aldrich Browse CompoZr Knockout ZFN at Sigma-Aldrich
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 Antibodies for KLK13 (Kallikrein 13)   Cell Culture Products  
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 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of KLK13
 SeqTarget long-range PCR primers for resequencing KLK13
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of KLK13
 GenScript Custom Purified and Recombinant Proteins Services for KLK13 GenScript cDNA clones with any tag delivered in your preferred vector for KLK13
 GenScript Custom Assay Services for KLK13 GenScript Custom Superior Antibodies Services for KLK13
 GenScript Custom overexpressing Cell Line Services for KLK13 CloneReady with Over 120,000 Genes
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 Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
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 Regulatory tfbs in KLK13 promoter
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 Novus Tissue Slides
 Antibodies for KLK13
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 Lysates for KLK13
 Browse antibodies at Epitomics
 Browse ProSpec Recombinant Proteins

 ELISAs and CLIAs for KLK13
       

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