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MYRIP Gene

protein-coding   GIFtS: 53

GC03P039826
myosin VIIA and Rab interacting protein
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
myosin VIIA and Rab interacting protein1 2     FLJ440252
SLAC2C1 2 3 5     MGC1300342
DKFZp586F10181 2     synaptotagmin-like protein homologue lacking C2 domains-c2
exophilin-81 2     rab effector MyRIP2
SLAC2-C1 2     Slp homologue lacking C2 domains2
Myosin-VIIa- and Rab-interacting protein2 3     OTTHUMP000002092072
Slp homolog lacking C2 domains c2 3     MGC1300352
MyRIP1     SlaC2-c3
OTTHUMP000002092092     Exophilin-83

External Ids:    HGNC: 191561   Entrez Gene: 259242   Ensembl: ENSG000001700117   UniProtKB: Q8NFW93   

Export aliases for MYRIP gene to outside databases

Previous GC identifers: GC03P039190 GC03P039084 GC03P039664 GC03P039811


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: MYRIP_HUMAN, Q8NFW9
Function: Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the
motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments (By similarity)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MYRIP gene promoter:
         E4BP4   CUTL1   Chx10   MyoD   Egr-1   Cdc5   POU2F1   E47   Pax-5   Arnt   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for MYRIP

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for MYRIP 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p22.1   Ensembl cytogenetic band:  3p22.1   HGNC cytogenetic band: 3p21.33

MYRIP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MYRIP gene location

GeneLoc gene densities for chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P039826:  view genomic region     (about GC identifiers)

Start:
39,850,405 bp from pter
End:
40,301,812 bp from pter
Size:
451,408 bases
Orientation:
plus strand
RefSeq DNA sequence:
NC_000003.11  NT_022517.18  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: MYRIP_HUMAN, Q8NFW9 (See protein sequence)
Recommended Name: Rab effector MyRIP  
Size: 859 amino acids; 95706 Da
Subunit: Binds MYO5A, MYO7A and F-actin (By similarity). Binds RAB27A that has been activated by GTP-binding via its
N-terminus
Subcellular location: Cytoplasm (By similarity). Note=In pre- and post-synaptic areas in photoreceptor cells and in the
basal microvilli of retinal pigment epithelium cells. Associated with melanosomes. Colocalizes with actin filaments
(By similarity)
Secondary accessions: Q569F7 Q8IUF5 Q9Y3V4

Explore the universe of human proteins at neXtProt for MYRIP: NX_Q8NFW9 

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_056275.2  

    ENSEMBL proteins: 
    ENSP00000398665 ENSP00000301972 ENSP00000389323 ENSP00000400916 ENSP00000413392 ENSP00000379519 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: MYRIP
    GenScript Custom Purified and Recombinant Proteins Services for MYRIP 
    Novus Biologicals Protein for MYRIP
    Novus Biologicals Lysate for MYRIP
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins

    5 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001750 photoreceptor outer segment IEA--
    GO:0005737 cytoplasm IEA--
    GO:0015629 actin cytoskeleton IEA--
    GO:0042470 melanosome IEA--
    GO:0045202 synapse IEA--
    About this table

    MYRIP for ontologies           About GeneDecksing



    Antibodies for MYRIP: 
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for MYRIP
    Browse R&D Systems for Antibodies
    OriGene Antibodies: MYRIP
    GenScript Custom Superior Antibodies Services for MYRIP 
    Novus Biologicals Antibodies for MYRIP
    Browse antibodies at Epitomics

    Assays for MYRIP: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for MYRIP 
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for MYRIP 


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    MYRIP for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR006788 Myelin-assoc_OBP
     IPR013083 Znf_RING/FYVE/PHD
     IPR010911 Rab-bd_domain
     IPR011011 Znf_FYVE_PHD

    Graphical View of Domain Structure for InterPro Entry Q8NFW9

    ProtoNet protein and cluster: Q8NFW9

    1 Blocks protein family: IPB000306 Zn-finger

    UniProtKB/Swiss-Prot: MYRIP_HUMAN, Q8NFW9
    Similarity: Contains 1 FYVE-type zinc finger
    Similarity: Contains 1 RabBD (Rab-binding) domain


    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    UniProtKB/Swiss-Prot: MYRIP_HUMAN, Q8NFW9
    Function: Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the
    motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments (By similarity)

    Inhib.
    RNA:
        
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for MYRIP
    Sigma-Aldrich shRNA for MYRIP
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): MYRIP
    OriGene shRNA RFP (see all 2): MYRIP
    OriGene basic RS shRNA (see all 2): MYRIP
    OriGene siRNA: MYRIP
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of MYRIP 
    miRNA:Sigma-Aldrich microRNA Mimics for MYRIP
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of MYRIP 
    8/17 SABiosciences Assays for microRNAs that regulate MYRIP (see all 17):
    hsa-miR-579 hsa-miR-202 hsa-miR-1271 hsa-miR-331-3p hsa-miR-200a hsa-miR-557 hsa-miR-340 hsa-miR-570

    Gene
    Editing:
    Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: MYRIP
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: MYRIP
    OriGene untagged cDNA clones in CMV expression vector: MYRIP
    OriGene 3'-UTR clone: MYRIP 
    Browse MicroRNA Expression Plasmids 
    GenScript cDNA clone with any tag delivered in your preferred vector: MYRIP 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:
      
    GenScript Custom overexpressing Cell Line Services for MYRIP 

    5/6 Gene Ontology (GO) molecular function terms (GO ID links to tree view) (see all 6):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003779 actin binding IEA--
    GO:0005515 protein binding IPI11964381
    GO:0008270 zinc ion binding NAS11964381
    GO:0017022 myosin binding IEA--
    GO:0017137 Rab GTPase binding IEA--
    About this table

    MYRIP for ontologies           About GeneDecksing


    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section

        SABiosciences Custom Pathway-Focused PCR Arrays for MYRIP 

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MYRIP

    4 Interacting proteins for MYRIP (Q8NFW91, 2) via UniProtKB, MINT, and/or STRING
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NCK1P163331, 2EBI-1759414,EBI-389883 MINT-7249054
    PIK3R1P279861, 2EBI-1759414,EBI-79464 MINT-7251934
    GRB2P629931EBI-1759414,EBI-401755
    --P310162MINT-7974810
    About this table

    1 Gene Ontology (GO) biological process term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006886 intracellular protein transport IEA--
    About this table

    MYRIP for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section
    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MYRIP


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section

    Inhib.
    RNA:
         
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for MYRIP
    Sigma-Aldrich shRNA for MYRIP
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): MYRIP
    OriGene shRNA RFP (see all 2): MYRIP
    OriGene basic RS shRNA (see all 2): MYRIP
    OriGene siRNA: MYRIP
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of MYRIP 
    miRNA: Sigma-Aldrich microRNA Mimics for MYRIP
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of MYRIP 
    8/17 SABiosciences Assays for microRNAs that regulate MYRIP (see all 17):
    hsa-miR-579 hsa-miR-202 hsa-miR-1271 hsa-miR-331-3p hsa-miR-200a hsa-miR-557 hsa-miR-340 hsa-miR-570
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: MYRIP
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: MYRIP
    OriGene untagged cDNA clones in CMV expression vector: MYRIP
    OriGene 3'-UTR Clone: MYRIP 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript cDNA clone with any tag delivered in your preferred vector: MYRIP 
    Primers: OriGene genome-wide validated SYBR primer pairs: MYRIP
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for MYRIP: PPH13250A

    REFSEQ mRNAs for MYRIP gene: 

    NM_015460.2  

    Additional cDNA sequence: 

    AB083783.1 AF396687.1 AK125334.1 AK126013.1 AK294714.1 AK310972.1 AK312412.1 AK316068.1 
    AL050090.1 BC092512.1 BC109311.1 BC109312.1 

    6 DOTS entries:

    DT.411498  DT.99954773  DT.120871429  DT.40246508  DT.439321  DT.75104804 

    24/51 AceView cDNA sequences (see all 51):

    AB083783 F07858 AW237186 AA195295 AL050090 AW665105 AA455367 AA258345 
    AA974678 AI827924 AA323164 BF478223 AW594282 F01507 AA579870 Z45990 
    AV692363 CF138044 AK125334 AK126013 AA317752 AA318334 Z41987 AI434843 

    highest scoring ESTs for MYRIP:

    AL050090 AA195099 AA195295 AA258345 AA258393 AA455367 AA579870 AA857208 AA974678 AI434843 

    Unigene Cluster for MYRIP:

    Myosin VIIA and Rab interacting protein
    Hs.594535  [show with all ESTs]
    Unigene Representative Sequence: BC092512


    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for MYRIP

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · 17b · 17c
    SP1:              -                                                                                                         
    SP2:              -                                                     -                                                   
    SP3:                                                                                                                        
    SP4:              -     -                                                                                                   
    SP5:              -                                                     -     -                                             

    About this scheme

    ECgene alternative splicing isoforms for MYRIP
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000444716 ENST00000302541(uc003cka.2 uc010hhu.2 uc010hhv.2 uc010hhw.2 uc011ayz.1)
    ENST00000425621 ENST00000458441 ENST00000458292 ENST00000475082(uc010hhx.1)
    ENST00000459828 ENST00000482033 ENST00000396217

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    MYRIP expression in normal and diseased human tissues

    1  / 2  / 3

    3 probe-sets matching MYRIP gene

    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    39602_at2, 3 U95-A 1 0.88 1.00 1.00 1.00 AL050090 1.00 1.00 1.00 1
    214156_at2, 3 U133-A 1 1.00 1.00 -- -- AL050090 1.00 1.00 1.00 1
    214156_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    About this table

    MYRIP for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    MYRIP gene expression
    MYRIP gene electronic northern expression
    MYRIP gene sage expression
    About these images

    CGAP SAGE TAG: TTATATGCAC

    SOURCE GeneReport for Unigene cluster: Hs.594535

    Expression variation in blood from EXPOLDB for MYRIP

    UniProtKB/Swiss-Prot: MYRIP_HUMAN, Q8NFW9
    Tissue specificity: Detected in brain, skin, heart, adrenal medulla, pancreas, intestine, liver, kidney, muscle and
    testis

    Primers: OriGene genome-wide validated SYBR primer pairs: MYRIP
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for MYRIP: PPH13250A
        SABiosciences Custom PCR Arrays for MYRIP 


    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section

    Orthologs for MYRIP gene from 5/7 species (see all 7)
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    MYRIP1   -- myosin VIIA and Rab interacting protein 86.84(n)
    86.96(a)
    485603  XM_542722.2  XP_542722.2 
    chimpanzee
    (Pan troglodytes)
    MYRIP1   -- myosin VIIA and Rab interacting protein 99.34(n)
    99.53(a)
    470796  XM_001135160.1  XP_001135160.1 
    cow
    (Bos taurus)
    MYRIP1   -- myosin VIIA and Rab interacting protein 85.39(n)
    84.71(a)
    522113  XM_600387.3  XP_600387.3 
    rat
    (Rattus norvegicus)
    Myrip1   -- myosin VIIA and Rab interacting protein 80.99(n)
    79.16(a)
    360034  NM_182844.1  NP_878264.1 
    mouse
    (Mus musculus)
    Myrip1 , 5 9 (71.50 cM)5
    myosin VIIA and Rab interacting protein1, 5 81.77(n)1
    80.33(a)1
    2450491  NM_144557.31  NP_653140.11 
     AB0837825  AF3966885  (see all 13)
    About this table        Species with no ortholog for MYRIP

    ENSEMBL Gene Tree for MYRIP (if available)

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
    Paralogs for MYRIP gene
    MLPH2  MOBP2  

    MYRIP for paralogs           About GeneDecksing



    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section

    10/4238 NCBI SNPs in MYRIP are shown (see all 4238)
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 3 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ----------
    rs7163931,2
    --39945784(+) ccaggC/Ttggag 1 -- int10--------
    rs7164621,2
    C,A,39987248(-) CAAATC/TTTAAA 1 -- int15Minor allele frequency- T:0.36NA EA WA 144
    rs7164631,2
    C,F,A,39987199(-) TTTAAC/TCTGCG 1 -- int17Minor allele frequency- T:0.30NS EA WA 530
    rs7252941,2
    C,F,A,39987989(-) accttT/Ccgttc 1 -- int19Minor allele frequency- C:0.32NS EA NA WA 564
    rs7252951,2
    C,F,A,39987922(-) tctggA/Gtaatt 1 -- int117Minor allele frequency- C:0.01NS EA NA WA 792
    rs7252961,2
    C,F,O,A,39987737(-) AGGTGA/GGTCTC 1 -- int117Minor allele frequency- G:0.30NS EA NA WA 1192
    rs7252971,2
    C,F,O,A,H,39987604(-) TTGTGC/TTTTAT 1 -- int120Minor allele frequency- A:0.09NS EA NA WA 842
    rs8712311,2
    C,F,A,39852825(-) ATCCTG/ATGAAC 1 -- int111Minor allele frequency- A:0.44NS EA NA WA 568
    rs8828221,2
    C,F,O,A,H,40167191(-) TTCTCT/CGATCC 1 -- int117Minor allele frequency- C:0.23MN NS EA NA WA 900
    rs8980921,2
    C,F,A,H,39886582(+) aggctA/CaatgA 1 -- int113Minor allele frequency- C:0.35NS EA NA WA 520
    About this table

    HapMap Linkage Disequilibrium images for MYRIP (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for MYRIP
         1 CNV: 91287
         1 Indel: 42611

    QIAGEN SeqTarget long-range PCR primers for resequencing MYRIP 

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    MYRIP for disorders           About GeneDecksing

    OMIM: 611790

    Human Genome Epidemiology (HuGE) Navigator: MYRIP (2 documents)

    Export disorders and mutations for MYRIP gene to outside databases

    (Possibly Related Articles in Doctor's Guide)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/21 PubMed articles for MYRIP gene, integrated from 7 sources (see all 21):
    (articles sorted by number of sources associating them with MYRIP)
    1. Slac2-c (synaptotagmin-like protein homologue lacking C2 domains-c), a novel linker protein that interacts with Rab27, myosin Va/VIIa, and actin. (PubMed id 12221080)1, 2, 3, 7 Fukuda M. and Kuroda T.S. (2002)
    2. MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomes. (PubMed id 11964381)1, 2, 3 El-Amraoui A.... Petit C. (2002)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    5. Genome-wide association identifies SKIV2L and MYRIP a s protective factors for age-related macular degeneration. (PubMed id 20861866)1 Kopplin L.J....Iyengar S.K. (2010)
    6. Rab27a and MyRIP regulate the amount and multimeric s tate of VWF released from endothelial cells. (PubMed id 19270261)1 Nightingale T.D....Cutler D.F. (2009)
    7. Intramanchette transport during primate spermiogenesis: expression of dynein, myosin Va, motor recruiter myosin Va, VIIa-Rab27a/b interacting protein, and Rab27b in the manchette during human and monkey spermiogenesis. (PubMed id 18478159)1 Hayasaka S....Okamura K. (2008)
    8. Global proteomic profiling of phosphopeptides using electron transfer dissociation tandem mass spectrometry. (PubMed id 17287340)2 Molina H.... Pandey A. (2007)
    9. MyRIP anchors protein kinase A to the exocyst complex. (PubMed id 17827149)1 Goehring A.S....Scott J.D. (2007)
    10. Genome-wide association of sleep and circadian phenotypes. (PubMed id 17903308)1 Gottlieb D.J....Wilk J.B. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 25924 HGNC: 19156 AceView: MYRIP Ensembl:ENSG00000170011 euGenes: HUgn25924
    ECgene: MYRIP H-InvDB: MYRIP

    (According to HUGE)
    About This Section
      --

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
      --

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
    About This Section
    Patent Information for MYRIP gene:
    Search GeneIP for patents involving MYRIP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
    Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
    About This Section

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services

     Predesigned and custom siRNAs for MYRIP Antibodies for MYRIP
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     "Your Favorite Gene" Pathways and Molecular Interaction Networks Browse Nano Scale siRNA at Sigma-Aldrich
     Browse iPSC Reprogramming Factors at Sigma-Aldrich Browse small molecules at Sigma-Aldrich
     Browse FLAG tag genes at Sigma-Aldrich Browse ELISAs at Sigma-Aldrich
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     DNA Damage/Repair Kits/Reagents   Multiplex/Array Assay Kits/Reagents  
     Cell Selection/Detection Kits/Reagents   ELISA/Assay Development Kits/Reagents  
     Phosphatase Activity Assays/Reagents   Recombinant/Natural Proteins  
     Tagged/untagged cDNA clones
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     Lysates
     Western blot validated antibodies
     shRNA in GFP-retroviral vector
     siRNA
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     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of MYRIP
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     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for MYRIP
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of MYRIP
     GenScript Custom Purified and Recombinant Proteins Services for MYRIP GenScript cDNA clones with any tag delivered in your preferred vector for MYRIP
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     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in MYRIP promoter
     Search Chromatin IP Primers for MYRIP
     RT2 qPCR Primer Assay for MYRIP
     GNC Network for MYRIP
     Assays for microRNAs that regulate MYRIP
     SABiosciences Custom PCR Arrays for MYRIP
     Search Tocris compounds for MYRIP
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
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     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     Antibodies for MYRIP
     Proteins for MYRIP
     Lysates for MYRIP
     Browse antibodies at Epitomics
     Browse ProSpec Recombinant Proteins

     ELISAs and CLIAs for MYRIP
           

    GeneCards Homepage - Last full update: 30 Dec 2010 - Incremental updates: 10 Jan 2011 , 10 Jan 2011

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