Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


Category   Symbol Source: HGNC EntrezGene Ensembl
GIFtS

Search by expression pattern Search by expression pattern



NOLC1 Gene

protein-coding   GIFtS: 51

GC10P097544
nucleolar and coiled-body phosphoprotein 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Products    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases & Descriptions
nucleolar and coiled-body phosphoprotein 11 2     HCV NS5A-transactivated protein 132 3
KIAA00351 2 3     140 kDa nucleolar phosphoprotein2 3
NOPP1301 2     NS5ATP132 3
P1301 2     nucleolar and coiled-body phosphprotein 12
NOPP1401 2     nucleolar protein p1302
Nucleolar 130 kDa protein2 3     HCV NS5A trans-regulated protein 132
Nucleolar phosphoprotein p1302 3     Nopp1403
Hepatitis C virus NS5A-transactivated protein 132 3     

External Ids:    HGNC: 156081   Entrez Gene: 92212   Ensembl: ENSG000001661977   UniProtKB: Q149783   

Export aliases for NOLC1 gene to outside databases

Previous GC identifers: GC10P102805 GC10P103145 GC10P104043 GC10P103576 GC10P103902


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: NOLC1_HUMAN, Q14978
Function: Related to nucleologenesis, may play a role in the maintenance of the fundamental structure of the fibrillar
center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities. May play an
important role in transcription catalyzed by RNA polymerase I

Gene Wiki entry for NOLC1 (Nucleolar phosphoprotein p130)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NOLC1 gene promoter:
         CREB   deltaCREB   NF-kappaB1   GATA-2   FOXO1a   c-Myc   Max   NF-kappaB   YY1   Arnt   
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for NOLC1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for NOLC1 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q24.32   Ensembl cytogenetic band:  10q24.32   HGNC cytogenetic band: 10q24.32

NOLC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NOLC1 gene location

GeneLoc gene densities for chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P097544:  view genomic region     (about GC identifiers)

Start:
97,544,003 bp from pter
End:
97,555,697 bp from pter
Size:
11,695 bases
Orientation:
plus strand

1 alternative location:
Chr10+ 103,911,933-103,923,627     
RefSeq DNA sequence:
NC_000010.10  NT_030059.13  

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: NOLC1_HUMAN, Q14978 (See protein sequence)
Recommended Name: Nucleolar and coiled-body phosphoprotein 1  
Size: 699 amino acids; 73603 Da
Subunit: Interacts with RNA polymerase I 194 kDa subunit (RPA194) and with casein kinase-II
Subcellular location: Nucleus, nucleolus. Cytoplasm. Note=Shuttles between the nucleolus and the cytoplasm. At
telophase it begins to assemble into granular-like pre-nucleolar bodies which are subsequently relocated to nucleoli
at the early G1-phase
Secondary accessions: Q15030 Q5VV70 Q9BUV3
Alternative splicing: 3 isoforms:  Q14978-1   Q14978-2   Q14978-3   

Explore the universe of human proteins at neXtProt for NOLC1: NX_Q14978 

Post-translational modifications:

  • Undergoes rapid and massive phosphorylation/dephosphorylation cycles on CK2 and PKC sites. There is evidence suggesting
  • that CDK1 kinase phosphorylates p130 at the M-phase1
  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_004732.2  

    ENSEMBL proteins: 
    ENSP00000359024 ENSP00000385410 ENSP00000413627 


    Human Recombinant Proteins 
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    GenScript Custom Purified and Recombinant Proteins Services for NOLC1 
    Novus Biologicals Protein for NOLC1
    Novus Biologicals Lysate for NOLC1
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins

    5 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634 nucleus IEA--
    GO:0005654 nucleoplasm ----
    GO:0005730 nucleolus IEA--
    GO:0005737 cytoplasm IEA--
    GO:0015030 Cajal body ----
    About this table

    NOLC1 for ontologies           About GeneDecksing



    Antibodies for NOLC1: 
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for NOLC1
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    GenScript Custom Superior Antibodies Services for NOLC1 
    Novus Biologicals Antibodies for NOLC1
    Browse antibodies at Epitomics

    Assays for NOLC1: 
    Browse Kits and Assays available from Millipore
    Browse ELISAs at Sigma-Aldrich
    OriGene Custom Immunoassay Development 
    Browse OriGene Fluorogenic Cell Assay Kits 
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for NOLC1 
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for NOLC1 


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    NOLC1 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR006594 LisH_dimerisation
     IPR007718 SRP40_C

    Graphical View of Domain Structure for InterPro Entry Q14978

    ProtoNet protein and cluster: Q14978

    2 Blocks protein families:
    IPB006594 Lissencephaly type-1-like homology motif
    IPB007718 SRP40


    UniProtKB/Swiss-Prot: NOLC1_HUMAN, Q14978
    Similarity: Contains 1 LisH domain


    (According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
    About This Section

    UniProtKB/Swiss-Prot: NOLC1_HUMAN, Q14978
    Function: Related to nucleologenesis, may play a role in the maintenance of the fundamental structure of the fibrillar
    center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities. May play an
    important role in transcription catalyzed by RNA polymerase I

    Inhib.
    RNA:
        
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for NOLC1
    Sigma-Aldrich shRNA for NOLC1
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): NOLC1
    OriGene shRNA RFP (see all 2): NOLC1
    OriGene basic RS shRNA (see all 2): NOLC1
    OriGene siRNA: NOLC1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of NOLC1 
    miRNA:Sigma-Aldrich microRNA Mimics for NOLC1
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of NOLC1 
    1 SABiosciences Assays for microRNA that regulate NOLC1:
    hsa-miR-888

    Gene
    Editing:
    Browse CompoZr Knockout ZFN at Sigma-Aldrich 

    Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    Browse iPSC Reprogramming Factors at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: NOLC1
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: NOLC1
    OriGene untagged cDNA clones in CMV expression vector: NOLC1
    OriGene 3'-UTR clone: NOLC1 
    Browse MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for NOLC1 
    Browse Sino Biological Human cDNA Clones

    Cell
    Lines:
      
    GenScript Custom overexpressing Cell Line Services for NOLC1 

    5/8 Gene Ontology (GO) molecular function terms (GO ID links to tree view) (see all 8):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166 nucleotide binding IEA--
    GO:0003700 sequence-specific DNA binding transcription factor activity ----
    GO:0005515 protein binding IPI17353931
    GO:0005524 ATP binding IEA--
    GO:0005525 GTP binding IEA--
    About this table

    NOLC1 for ontologies           About GeneDecksing


    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
    About This Section


    NOLC1 for pathways           About GeneDecksing

    1 Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Pathway for  NOLC1
        Acute Phase Response Signaling

        SABiosciences Custom Pathway-Focused PCR Arrays for NOLC1 

        Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Molecular Interaction Network for NOLC1
        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NOLC1

    5/575 Interacting proteins for NOLC1 (Q149781, 2) via UniProtKB, MINT, and/or STRING (see all 575)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    YWHAZP631041, 2EBI-396155,EBI-347088 MINT-3296095
    ARRB1P494071EBI-396155,EBI-743313
    ARRB2P321211EBI-396155,EBI-714559
    ABCF1Q8NE712MINT-7945693
    ABCF3Q9NUQ82MINT-7945693
    About this table

    5/9 Gene Ontology (GO) biological process terms (GO ID links to tree view) (see all 9):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006364 rRNA processing TAS7657714
    GO:0006970 response to osmotic stress ----
    GO:0007000 nucleolus organization ----
    GO:0007049 cell cycle TAS7657714
    GO:0007067 mitosis TAS7657714
    About this table

    NOLC1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    NOLC1 for compounds           About GeneDecksing

    Browse Small Molecules at Sigma-Aldrich
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NOLC1
    3 Novoseek chemical compound relationships for NOLC1 gene
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    actinomycin d 36.3 1 7657714 (1)
    tyrosine 9.5 6 2110361 (2), 7929090 (1), 8843705 (1)
    serine 6.71 1 8972203 (1)
    About this table



    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore,
    siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
    About This Section

    Inhib.
    RNA:
         
    Browse for Gene Knock-down Tools from Millipore
    Browse Nano Scale siRNA at Sigma-Aldrich
    Sigma-Aldrich esiRNA and siRNA for NOLC1
    Sigma-Aldrich shRNA for NOLC1
    OriGene 29mer shRNA kits in GFP-retroviral vector (see all 2): NOLC1
    OriGene shRNA RFP (see all 2): NOLC1
    OriGene basic RS shRNA (see all 2): NOLC1
    OriGene siRNA: NOLC1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of NOLC1 
    miRNA: Sigma-Aldrich microRNA Mimics for NOLC1
    Browse microRNA target validation systems at Sigma-Aldrich 
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of NOLC1 
    1 SABiosciences Assays for microRNA that regulate NOLC1:
    hsa-miR-888
    Clones: Browse FLAG tag genes at Sigma-Aldrich
    OriGene GFP tagged cDNA clones in CMV expression vector: NOLC1
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector: NOLC1
    OriGene untagged cDNA clones in CMV expression vector: NOLC1
    OriGene 3'-UTR Clone: NOLC1 
    Browse OriGene MicroRNA Expression Plasmids 
    GenScript Custom cDNA clone Services for NOLC1 
    Primers: OriGene genome-wide validated SYBR primer pairs: NOLC1
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for NOLC1: PPH09961A

    REFSEQ mRNAs for NOLC1 gene: 

    NM_004741.3  

    Additional cDNA sequence: 

    AK056755.1 AK225101.1 AK314363.1 AY820769.1 BC001883.1 BC006769.2 CR592002.1 CR602162.1 
    CR608343.1 CR609020.1 CR614920.1 D21262.1 L37710.1 Z34289.1 

    19 DOTS entries:

    DT.95375575  DT.95375581  DT.100887542  DT.454013  DT.100887523  DT.92453349  DT.95264724  DT.100031741 
    DT.100758167  DT.100887529  DT.101958343  DT.102833293  DT.121256181  DT.100887513  DT.92453356  DT.100887538 
    DT.86855693  DT.95149496  DT.99991864 

    24/660 AceView cDNA sequences (see all 660):

    AI418692 AI887878 BG110857 BM849059 AK056755 BU177326 BM799006 H46706 
    BG391650 BP335958 AA983639 AL520884 AW139816 BI093466 AW302583 CA405637 
    CB136250 CD243204 BF591052 BI092441 BG392354 BQ436245 BP358879 BQ222981 

    highest scoring ESTs for NOLC1:

    D21262 AA034227 AA037820 AA037821 AA079325 AA085577 AA112312 AA135890 AA191216 AA196450 

    Unigene Cluster for NOLC1:

    Nucleolar and coiled-body phosphoprotein 1
    Hs.523238  [show with all ESTs]
    Unigene Representative Sequence: NM_004741


    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for NOLC1 (see all 9)

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b
    SP1:                                                                          -                                                                     
    SP2:                                                                                                                                                
    SP3:                          -     -     -                                   -                                                                     
    SP4:                                                                          -                                                                     
    SP5:                                                                                                                                                

    About this scheme

    ECgene alternative splicing isoforms for NOLC1
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000488254 ENST00000464969 ENST00000370007 ENST00000405356(uc001kup.2)
    ENST00000477977 ENST00000461421 ENST00000476468 ENST00000429062(uc001kuo.2 uc001kuq.2 uc009xxb.1 uc001kur.2)


    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Primers from OriGene and/or SABiosciences )
    About This Section

    NOLC1 expression in normal and diseased human tissues

    1  / 2  / 3

    7 probe-sets matching NOLC1 gene

    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    36597_at2, 3 U95-A 1 0.88 1.00 1.00 1.00 D21262 1.00 1.00 1.00 1
    205895_s_at2, 3 U133-A 1 1.00 1.00 -- -- NM_004741 0.60 1.00 0.82 1
    211949_s_at2, 3 U133-A 1 1.00 1.00 -- -- AI355279 0.60 1.00 0.82 1
    211951_at2, 3 U133-A 1 1.00 1.00 -- -- D21262 1.00 1.00 1.00 1
    205895_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    211949_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    211951_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    About this table

    NOLC1 for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    NOLC1 gene expression
    NOLC1 gene electronic northern expression
    NOLC1 gene sage expression
    About these images

    CGAP SAGE TAG: GTAAAAGTTC

    SOURCE GeneReport for Unigene cluster: Hs.523238
    Primers: OriGene genome-wide validated SYBR primer pairs: NOLC1
    Browse OriGene validated miRNA SYBR primer pairs 
    SABiosciences RT2 qPCR Primer Assay for NOLC1: PPH09961A
        SABiosciences Custom PCR Arrays for NOLC1 


    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section

    Orthologs for NOLC1 gene from 5/15 species (see all 15)
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    NOLC11   -- nucleolar and coiled-body phosphoprotein 1 85.56(n)
    82.59(a)
    609496  XM_846755.1  XP_851848.1 
    chimpanzee
    (Pan troglodytes)
    NOLC11   -- nucleolar and coiled-body phosphoprotein 1 99.19(n)
    98.71(a)
    745419  XM_001170994.1  XP_001170994.1 
    cow
    (Bos taurus)
    NOLC11   -- nucleolar and coiled-body phosphoprotein 1 84.37(n)
    82.29(a)
    513278  NM_001075608.1  NP_001069076.1 
    rat
    (Rattus norvegicus)
    Nolc11   -- nucleolar and coiled-body phosphoprotein 1 80.39(n)
    75.65(a)
    64896  NM_022869.1  NP_074060.1 
    mouse
    (Mus musculus)
    Nolc11 , 5 19 (38.75 cM)5
    nucleolar and coiled-body phosphoprotein 11, 5 80.81(n)1
    77.32(a)1
    707691  NM_001039353.11  NP_001034442.11 
     AA4080775  AA5368185  (see all 27)
    About this table        Species with no ortholog for NOLC1

    ENSEMBL Gene Tree for NOLC1 (if available)

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section
    Paralogs for NOLC1 gene
    TCOF12  

    NOLC1 for paralogs           About GeneDecksing



    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
    About This Section
    QIAGEN SeqTarget long-range PCR primers for resequencing NOLC1 

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    NOLC1 for disorders           About GeneDecksing

    OMIM: 602394

    1 Novoseek disease relationship for NOLC1 gene

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    response acute phase 54.8 1 12167624 (1)
    About this table

    Human Genome Epidemiology (HuGE) Navigator: NOLC1 (1 document)

    Export disorders and mutations for NOLC1 gene to outside databases

    (Possibly Related Articles in Doctor's Guide)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
    About This Section

    10/63 PubMed articles for NOLC1 gene, integrated from 7 sources (see all 63):
    (articles sorted by number of sources associating them with NOLC1)
    1. Cell-cycle-dependent alterations of a highly phosphorylated nucleolar protein p130 are associated with nucleologenesis. (PubMed id 7657714)1, 2, 3, 7 Pai C.-Y.... Yeh N.-H. (1995)
    2. Human Nopp140, which interacts with RNA polymerase I: implications for rRNA gene transcription and nucleolar structural organization. (PubMed id 10567578)1, 2, 3, 7 Chen H.-K.... Yeh N.-H. (1999)
    3. The nucleolar phosphoprotein P130 is a GTPase/ATPase with intrinsic property to form large complexes triggered by F- and Mg2+. (PubMed id 9016786)1, 2, 7 Chen H.-K. and Yeh N.-H. (1997)
    4. Cell proliferation-dependent expression of two isoforms of the nucleolar phosphoprotein p130. (PubMed id 8630004)1, 2, 7 Pai C.-Y. and Yeh N.-H. (1996)
    5. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
    6. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    7. Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. (PubMed id 15144186)1, 2 Brill L.M....Peters E.C. (2004)
    8. Large-scale characterization of HeLa cell nuclear phosphoproteins. (PubMed id 15302935)1, 2 Beausoleil S.A....Gygi S.P. (2004)
    9. Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. (PubMed id 7584026)1, 2 Nomura N.... Tabata S. (1994)
    10. Identification and characterization of a nucleolar phosphoprotein, Nopp140, as a transcription factor. (PubMed id 8972203)1, 7 Miau L.H....Lee S.C. (1997)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9221 HGNC: 15608 AceView: NOLC1 Ensembl:ENSG00000166197 euGenes: HUgn9221
    ECgene: NOLC1 H-InvDB: NOLC1

    (According to HUGE)
    About This Section
    HUGE: KIAA0035

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
      --

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
    About This Section
    Patent Information for NOLC1 gene:
    Search GeneIP for patents involving NOLC1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
    Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
    About This Section

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services

     Predesigned and custom siRNAs for NOLC1 Antibodies for NOLC1
     Super-pooled esiRNAs for NOLC1 Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for NOLC1 microRNA Mimics for NOLC1
     "Your Favorite Gene" Pathways and Molecular Interaction Networks Browse Nano Scale siRNA at Sigma-Aldrich
     Browse iPSC Reprogramming Factors at Sigma-Aldrich Browse small molecules at Sigma-Aldrich
     Browse FLAG tag genes at Sigma-Aldrich Browse ELISAs at Sigma-Aldrich
     Browse microRNA Target Validation Systems at Sigma-Aldrich Browse CompoZr Knockout ZFN at Sigma-Aldrich
    feedback
      
     Antibodies   Cell Culture Products  
     ELISAs   Flow Cytometry Kits  
     Primer Pairs   Kinase Activity Assays/Reagents  
     ELISpot Kits/Development Modules   TFB/Immunoprecipitation Assays  
     Apoptosis Detection Kits/Reagents   Protease Activity Assays/Reagents  
     DNA Damage/Repair Kits/Reagents   Multiplex/Array Assay Kits/Reagents  
     Cell Selection/Detection Kits/Reagents   ELISA/Assay Development Kits/Reagents  
     Phosphatase Activity Assays/Reagents   Recombinant/Natural Proteins  
     Tagged/untagged cDNA clones
     Validated SYBR primer pairs
     Purified proteins from HEK293T cells
     Lysates
     Western blot validated antibodies
     shRNA in GFP-retroviral vector
     siRNA
     Custom Immunoassay Development
     Fluorogenic Cell Assay Kits
     miRNA Primers for qPCR Assays
     3' UTR Clones for miRNA Target Studies
     miRNA Expression Plasmids

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of NOLC1
     SeqTarget long-range PCR primers for resequencing NOLC1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for NOLC1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of NOLC1
     GenScript Custom Purified and Recombinant Proteins Services for NOLC1 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for NOLC1
     GenScript Custom Assay Services for NOLC1 GenScript Custom Superior Antibodies Services for NOLC1
     GenScript Custom overexpressing Cell Line Services for NOLC1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in NOLC1 promoter
     Search Chromatin IP Primers for NOLC1
     RT2 qPCR Primer Assay for NOLC1
     GNC Network for NOLC1
     Assays for microRNAs that regulate NOLC1
     SABiosciences Custom PCR Arrays for NOLC1
     Search Tocris compounds for NOLC1
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     Antibodies for NOLC1
     Proteins for NOLC1
     Lysates for NOLC1
     Browse antibodies at Epitomics
     Browse ProSpec Recombinant Proteins

     ELISAs and CLIAs for NOLC1
           

    GeneCards Homepage - Last full update: 30 Dec 2010 - Incremental updates: 9 Jan 2011 , 10 Jan 2011

    View Random Gene

    Category
    GIFtS Group
    The GeneCards human gene database gene index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    NOLC1 gene at Home site.
    hostname: www-ab3 db genecards_305 index build: 81e solr: 1.4