Aliases &
Descriptions
for NSD1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| nuclear receptor binding SET domain protein 11 2 | | STO2 5 | | ARA2671 2 3 5 | | Sotos syndrome1 | | KMT3B1 2 3 | | androgen receptor-associated coregulator 2672 | | FLJ222631 2 | | FLJ106842 | | Androgen receptor coactivator 267 kDa protein2 3 | | DKFZp666C1632 | | Lysine N-methyltransferase 3B2 3 | | SOTOS2 | | Androgen receptor-associated protein of 267 kDa2 3 | | FLJ446282 | | Nuclear receptor-binding SET domain-containing protein 12 3 | | histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific2 | | H4-K20-HMTase2 3 | | OTTHUMP000001614322 | | NR-binding SET domain-containing protein2 3 | | EC 2.1.1.433 | | H3-K36-HMTase2 3 | | |
Export aliases for NSD1 gene to outside databasesPrevious GC identifers: GC05P176935 GC05P177404 GC05P176496 GC05P176541 GC05P176493 GC05P176560 |
Summaries
for NSD1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for NSD1:
This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 planthomeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR)transactivation, and this enhancement can be increased further in the presence of other androgen receptor associatedcoregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctionaltranscriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. Oneversion of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurringwithin nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 andnucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for thisgene. (provided by RefSeq)
UniProtKB/Swiss-Prot: NSD1_HUMAN, Q96L73Function: Histone methyltransferase. Preferentially methylates 'Lys-36' of histone H3 and 'Lys-20' of histone H4 (invitro) (By similarity). Transcriptional intermediary factor capable of both negatively or positively influencingtranscription, depending on the cellular context
|
Genomic Views
for NSD1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NSD1 gene promoter:
Arnt USF1 POU3F2 XBP-1 CREB deltaCREB NRSF form 2 NRSF form 1 FOXO1a AP-2alphaA
Other transcription factors
Search SABiosciences Chromatin IP Primers for NSD1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for NSD1  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q35 Ensembl cytogenetic band: 5q35.2 HGNC cytogenetic band: 5q35NSD1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05P171481: view genomic region
(about GC identifiers)
Start:
|
171,481,615 bp from pter |
End:
|
171,647,948 bp from pter |
Size:
|
166,334 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr5+ 176,560,026-176,727,216 |
|
Proteins
for NSD1 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: NSD1_HUMAN, Q96L73 (See
protein sequence)Recommended Name: Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific Size: 2696 amino acids; 296652 Da
Subunit: Interacts with the ligand-binding domains of RARA and THRA in the absence of ligand; in the presence of ligandthe interaction is severely disrupted but some binding still occurs. Interacts with the ligand-binding domains of RXRAand ESRRA only in the presence of ligand. Interacts with ZNF496 (By similarity). Interacts with AR DNA- andligand-binding domains
Subcellular location: Nucleus. Chromosome (Probable)
Secondary accessions: Q96PD8 Q96RN7Alternative splicing: 3 isoforms: Q96L73-1 Q96L73-2 Q96L73-3 Explore the universe of human proteins at neXtProt for NSD1: NX_Q96L73
Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins (2 alternative transcripts):
NP_071900.2 NP_758859.1
ENSEMBL proteins: ENSP00000343209 ENSP00000395929 ENSP00000424024 ENSP00000422996 ENSP00000423372 ENSP00000423982 ENSP00000425120 ENSP00000426428 ENSP00000348031 ENSP00000354310 ENSP00000391623 ENSP00000364499 ENSP00000423048 ENSP00000424096 ENSP00000346111
Human Recombinant Proteins
2 Gene Ontology (GO) cellular component terms (GO ID links to tree view): About this table
NSD1 for ontologies About GeneDecksing
Antibodies for NSD1:
Assays for NSD1: |
Protein
Domains/
Families
for NSD1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NSD1 for domains About GeneDecksing
5/10 InterPro domains/families (see all 10):Graphical View of Domain Structure for InterPro Entry Q96L73ProtoNet protein and cluster: Q96L73 5 Blocks protein families: IPB000313 PWWP domain IPB001214 Nuclear protein SET IPB001841 Zn-finger IPB001965 Zn-finger-like IPB003616 SET-related region
UniProtKB/Swiss-Prot: NSD1_HUMAN, Q96L73Similarity: Belongs to the histone-lysine methyltransferase familySimilarity: Contains 1 AWS domainSimilarity: Contains 4 PHD-type zinc fingersSimilarity: Contains 1 post-SET domainSimilarity: Contains 2 PWWP domainsSimilarity: Contains 1 SET domain |
Gene Function
for NSD1 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
UniProtKB/Swiss-Prot: NSD1_HUMAN, Q96L73Function: Histone methyltransferase. Preferentially methylates 'Lys-36' of histone H3 and 'Lys-20' of histone H4 (invitro) (By similarity). Transcriptional intermediary factor capable of both negatively or positively influencingtranscription, depending on the cellular contextCatalytic activity: S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine +N(6)-methyl-L-lysine-[histone]Enzyme Number (IUBMB): EC 2.1.1.43
5/19 Gene Ontology (GO) molecular function terms (GO ID links to tree view) (see all 19): About this table
NSD1 for ontologies About GeneDecksing
Animal Models: 3 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Nsd1):
NSD1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for NSD1 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
NSD1 for pathways About GeneDecksing
2  Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Pathways for NSD1
1  Kegg Pathway (Kegg details for NSD1):
SABiosciences Pathway-Focused PCR Arrays including NSD1: PAHS-085A PAHS-086A
Sigma-Aldrich "Your Favorite Gene" (powered by Ingenuity) Molecular Interaction Network for NSD1
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NSD1
5/14 Interacting proteins for NSD1 (ENSP000003480313) via UniProtKB, MINT, and/or STRING (see all 14)About this table
5/6 Gene Ontology (GO) biological process terms (GO ID links to tree view) (see all 6): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000122 | negative regulation of transcription from RNA polymerase II promoter |
ISS | -- | | GO:0001702 | gastrulation with mouth forming second |
IEA | -- | | GO:0016568 | chromatin modification |
IEA | -- | | GO:0016571 | histone methylation |
ISS | -- | | GO:0045449 | regulation of transcription |
IEA | -- |
About this table
NSD1 for ontologies About GeneDecksing
|
Drugs & Compounds
for NSD1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for NSD1
|
Transcripts
for NSD1 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for NSD1 gene (2 alternative transcripts): NM_022455.4 NM_172349.2 24/168 AceView cDNA sequences (see all 168): BU101540 AW962112 BM835068 BM457114 BC021961 AK055187 AW196354 AA972919 AA872027 AI092329 AK025916 BX089603 NM_022455 AY049721 AI524180 AV725878 CK431014 AF380302 BM754679 BE885420 AI590839 AF395588 AA443596 AL832983
 highest scoring ESTs for NSD1:AI590839 AA443596 AA872027 AA903829 AA972919 AF085858 AF380302 AF395588 AI524180 AI741927
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for NSD1
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20a | · | 20b | ^ | 21 | ^ | 22a | · | 22b | ^ | 23a | · | 23b | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for NSD1
17 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000347982 ENST00000439151(uc003mfp.2 uc003mfr.3 uc003mfs.1 uc011dfx.1)
ENST00000503056 ENST00000504457 ENST00000508896 ENST00000510954 ENST00000508029
ENST00000511258 ENST00000355783 ENST00000361032 ENST00000424831(uc003mfq.2)
ENST00000512992 ENST00000375350 ENST00000513736 ENST00000515735 ENST00000505395
ENST00000354179(uc003mft.3)
|
Expression
for NSD1 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| NSD1 expression in normal and diseased human tissues
1 / 2 / 3 9 probe-sets matching NSD1 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 92098_at2, 3
|
U95-D |
1 |
1.00 |
1.00 |
0.59 |
1.16 |
AI524180 |
0.80 |
1.00 |
0.91 |
1 |
| 48066_at2, 3
|
U95-B |
1 |
1.00 |
1.00 |
-0.00 |
1.28 |
AI768720 |
0.20 |
0.33 |
0.27 |
2 |
| 49812_at2, 3
|
U95-B |
1 |
1.00 |
1.00 |
0.17 |
1.27 |
AI590839 |
1.00 |
1.00 |
1.00 |
1 |
| 68705_at2, 3
|
U95-E |
1 |
0.81 |
1.00 |
0.28 |
0.59 |
H68211 |
0.80 |
1.00 |
0.91 |
1 |
| 79236_at2, 3
|
U95-E |
1 |
0.69 |
1.00 |
0.79 |
0.75 |
AA552939 |
0.60 |
1.00 |
0.82 |
1 |
| 219084_at2, 3
|
U133-A |
1 |
1.00 |
1.00 |
-- |
-- |
NM_022455 |
0.60 |
1.00 |
0.82 |
1 |
| 225654_at2, 3
|
U133-B |
1 |
1.00 |
1.00 |
-- |
-- |
AI768720 |
0.20 |
0.33 |
0.27 |
2 |
| 219084_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 225654_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
NSD1 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: TACTGTAATT
UniProtKB/Swiss-Prot: NSD1_HUMAN, Q96L73Tissue specificity: Expressed in the fetal/adult brain, kidney, skeletal muscle, spleen, and the thymus, and faintly inthe lung
SABiosciences Expression via Pathway-Focused PCR Arrays including NSD1: PAHS-085A PAHS-086A
|
Orthologs
for NSD1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for NSD1 gene from 5/9 species (see all 9)
About this table Species with no ortholog for NSD1
ENSEMBL Gene Tree for NSD1 (if available) |
Paralogs
for NSD1 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for NSD1 gene
- SETD22 ASH1L2 WHSC12 WHSC1L12
NSD1 for paralogs About GeneDecksing
|
Genomic Variants
for NSD1 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 5 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for NSD1 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for NSD1
2 CNVs: 51638 3589 | | QIAGEN SeqTarget long-range PCR primers for resequencing NSD1 |
|
Disorders & Mutations
for NSD1 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
Novoseek, PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NSD1 for disorders About GeneDecksing
OMIM: 606681 disorders: 117550 601626 277590 130650 UniProtKB/Swiss-Prot: NSD1_HUMAN, Q96L73
Defects in NSD1 are the cause of Sotos syndrome [MIM:117550]; also known as cerebral gigantism. It is adisorder characterized by excessively rapid growth, acromegalic features, and a nonprogressive cerebral disorder withmental retardation. High-arched palate and prominent jaw are noted in several patients. Most cases of Sotos syndromeare sporadic and may represent new dominant mutation Defects in NSD1 are the cause of Weaver syndrome (WES) [MIM:277590]. WES is a syndrome of accelerated growthand osseous maturation, unusual craniofacial appearance, hoarse and low-pitched cry, and hypertonia with camptodactyly Defects in NSD1 are a cause of Beckwith-Wiedemann syndrome (BWS) [MIM:130650]. BWS is a geneticallyheterogeneous disorder characterized by anterior abdominal wall defects including exomphalos (omphalocele), pre- andpostnatal overgrowth, and macroglossia. Additional less frequent complications include specific developmental defectsand a predisposition to embryonal tumors Note=A chromosomal aberration involving NSD1 is found in childhood acute myeloid leukemia. Translocationt(5;11)(q35;p15.5) with NUP98 Note=A chromosomal aberration involving NSD1 is found in an adult form of myelodysplastic syndrome (MDS).Insertion of NUP98 into NSD1 generates a NUP98-NSD1 fusion product
10/12  Novoseek disease relationships for NSD1 gene (see all 12)
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| sotos syndrome |
99 |
118 |
14571271 (6), 11896389 (4), 14997421 (4), 15452385 (4) (see all 48) |
| weaver syndrome |
95.1 |
11 |
12464997 (3), 12807965 (2), 14571271 (2), 16232326 (2) (see all 5) |
| macrocephaly |
91 |
11 |
18001468 (5), 14571271 (2), 16010675 (1), 16770806 (1) (see all 5) |
| developmental delay |
75.9 |
2 |
15452385 (1), 16970856 (1) |
| mental retardation |
66.5 |
12 |
16192740 (2), 14571271 (2), 12807965 (1), 18682256 (1) (see all 5) |
| beckwith-wiedemann syndrome |
60 |
3 |
16010674 (1), 16192740 (1), 14997421 (1) |
| aml childhood |
56.3 |
2 |
11493482 (1), 12353270 (1) |
| heart defects congenital |
50.8 |
2 |
15742365 (1), 19596467 (1) |
| short stature |
48.7 |
1 |
16770806 (1) |
| congenital disorders |
39.2 |
1 |
16202954 (1) |
About this table
GeneTests: NSD1
Sotos Syndrome
Locus Specific Mutation Databases (LSDB): NSD1
Human Gene Mutation Database (HGMD): NSD1
Genetic Association Database (GAD): NSD1
Human Genome Epidemiology (HuGE) Navigator: NSD1 (7 documents)
Export disorders and mutations for NSD1 gene to outside databases
|
Medical News
for NSD1 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for NSD1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
10/91 PubMed articles for NSD1 gene, integrated from 7 sources (see all 91):
(articles sorted by number of sources associating them with NSD1)- Haploinsufficiency of NSD1 causes Sotos syndrome. (PubMed id 11896389)1, 2, 3, 7 Kurotaki N.... Matsumoto N. (2002)
- Molecular characterization of NSD1, a human homologue of the mouse Nsd1 gene. (PubMed id 11733144)1, 2, 7 Kurotaki N....Matsumoto N. (2001)
- NSD1 mutations are the major cause of Sotos syndrome and occur in some cases of Weaver syndrome but are rare in other overgrowth phenotypes. (PubMed id 12464997)1, 2, 7 Douglas J.... Rahman N. (2003)
- Spectrum of NSD1 mutations in Sotos and Weaver syndromes. (PubMed id 12807965)1, 2, 7 Rio M.... Cormier-Daire V. (2003)
- Mutation analysis of the NSD1 gene in a group of 59 patients with congenital overgrowth. (PubMed id 15742365)1, 4, 7 Cecconi M....Faravelli F. (2005)
- Paradoxical NSD1 mutations in Beckwith-Wiedemann syndrome and 11p15 anomalies in Sotos syndrome. (PubMed id 14997421)1, 2, 7 Baujat G.... Colleaux L. (2004)
- A novel gene, NSD1, is fused to NUP98 in the t(5;11)(q35;p15.5) in de novo childhood acute myeloid leukemia. (PubMed id 11493482)1, 2, 7 Jaju R.J....Wainscoat J.S. (2001)
- Mutations in the NSD1 gene in patients with Sotos syndrome associate with endocrine and paracrine alterations in the IGF system. (PubMed id 15362962)1, 4, 7 De Boer L....Wit J.M. (2004)
- Cryptic insertion producing two NUP98/NSD1 chimeric transcripts in adult refractory anemia with an excess of blasts. (PubMed id 15382262)1, 2, 7 La Starza R.... Mecucci C. (2004)
- Identification and characterization of a novel androgen receptor coregulator ARA267-alpha in prostate cancer cells. (PubMed id 11509567)1, 2 Wang X....Chang C. (2001)
|
External Searches for NSD1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NSD1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NSD1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NSD1 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for NSD1 gene:
Search GeneIP for patents involving NSD1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NSD1 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
 | |
 |
| | | |
 |
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| | |
 |  |  |  | |
| |  | Search Tocris compounds for NSD1 |
| |  |  |  |  | | | | |
 | | | ELISAs and CLIAs for NSD1 |
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