Aliases &
Descriptions
for NUP205 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| nucleoporin 205kDa1 2 | | 205 kDa nucleoporin2 3 | | KIAA02251 3 | | chromosome 7 open reading frame 141 | | Nucleoporin Nup2052 3 | | nuclear pore complex protein Nup2052 | | C7orf142 3 | | |
Export aliases for NUP205 gene to outside databasesPrevious GC identifers: GC07P134659 GC07P134660 GC07P134699 GC07P134893 GC07P135242 |
Summaries
for NUP205 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for NUP205 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NUP205 gene promoter:
C/EBPalpha YY1 GR-alpha GR-beta E2F E2F-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for NUP205
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q33 Ensembl cytogenetic band: 7q33 HGNC cytogenetic band: 7q31.32NUP205 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P129545: view genomic region
(about GC identifiers)
Start:
|
129,545,544 bp from pter |
End:
|
129,636,349 bp from pter |
Size:
|
90,806 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr7+ 135,242,667-135,333,505 |
RefSeq DNA sequence:- NC_000007.13 NT_007933.15 NT_079596.2
|
Proteins
for NUP205 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: NU205_HUMAN, Q92621 (See
protein sequence)Recommended Name: Nuclear pore complex protein Nup205 Size: 2012 amino acids; 227922 Da
Subunit: Interacts with NUP93 and NUP35/NUP53
Subcellular location: Nucleus, nuclear pore complex (Potential)
Sequence caution: Sequence=BAA13214.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A6H8X3 Q86YC1Explore the universe of human proteins at neXtProt for NUP205: NX_Q92621
Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_055950.1
ENSEMBL proteins: ENSP00000400291 ENSP00000401983 ENSP00000405469 ENSP00000285968 ENSP00000415377
Human Recombinant Proteins
3 Gene Ontology (GO) cellular component terms (GO ID links to tree view): About this table
NUP205 for ontologies About GeneDecksing
Antibodies for NUP205:
Assays for NUP205: |
Protein
Domains/
Families
for NUP205 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NUP205 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q92621ProtoNet protein and cluster: Q92621 |
Gene Function
for NUP205 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
1 Gene Ontology (GO) molecular function term (GO ID links to tree view): About this table
NUP205 for ontologies About GeneDecksing
|
Pathways & Interactions
for NUP205 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
NUP205 for pathways About GeneDecksing
1  Kegg Pathway (Kegg details for NUP205):
SABiosciences Custom Pathway-Focused PCR Arrays for NUP205
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NUP205
5/50 Interacting proteins for NUP205 (Q926211, 2 ENSP000002859683) via UniProtKB, MINT, and/or STRING (see all 50)About this table
5/11 Gene Ontology (GO) biological process terms (GO ID links to tree view) (see all 11): About this table
NUP205 for ontologies About GeneDecksing
|
Drugs & Compounds
for NUP205 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for NUP205
|
Transcripts
for NUP205 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for NUP205 gene: NM_015135.2 Additional cDNA sequence: AK293497.1 AK297307.1 BC044255.1 BC063612.1 BC073947.1 BC094868.1 BC136624.1 BC146784.1 CR600008.1 CR610966.1 D86978.1 13 DOTS entries: DT.216846 DT.86849832 DT.100886015 DT.92440077 DT.100803838 DT.75188677 DT.92054291 DT.95144879 DT.70102401 DT.91947655 DT.92440072 DT.95144880 DT.95144883 24/279 AceView cDNA sequences (see all 279): AI951952 BU617046 BF475675 AI653264 BM555167 AA600190 CB120684 BQ055154 BQ437741 BG680682 AA053350 BQ921736 CR610966 BQ215184 AI076510 AL526600 AI625579 AA361216 BG253232 CD678650 BM830564 BQ061932 AA485923 BM473264
 highest scoring ESTs for NUP205:D86978 AA053350 AA130370 AA150086 AA461171 AA600190 AA732580 AI074610 AI243322 AI380208 Unigene Cluster for NUP205: Nucleoporin 205kDa Hs.727517 [show with all ESTs]Unigene Representative Sequence: BC146784
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for NUP205
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16 | ^ | 17 | ^ | 18a | · | 18b | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ |
|---|
|
| SP1: | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 24 | ^ | 25 | ^ | 26 | ^ | 27 | ^ | 28 | ^ | 29 | ^ | 30 | ^ | 31 | ^ | 32 | ^ | 33 | ^ | 34 | ^ | 35 | ^ | 36 | ^ | 37 | ^ | 38 | ^ | 39 | ^ | 40 | ^ | 41a | · | 41b | ^ | 42 | ^ | 43 | ^ | 44 | ^ | 45 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for NUP205
13 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000461255 ENST00000489493 ENST00000451477 ENST00000477620 ENST00000490439
ENST00000472132 ENST00000440390 ENST00000448354 ENST00000463247 ENST00000491089
ENST00000285968(uc011kqa.1 uc003vsw.2 uc003vsx.2) ENST00000462316
ENST00000417116
|
Expression
for NUP205 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| NUP205 expression in normal and diseased human tissues
1 / 2 / 3 6 probe-sets matching NUP205 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 88818_at2, 3
|
U95-D |
1 |
1.00 |
1.00 |
0.96 |
1.17 |
AI679933 |
0.60 |
1.00 |
0.82 |
1 |
| 38728_at2, 3
|
U95-A |
1 |
1.00 |
1.00 |
0.90 |
0.83 |
D86978 |
1.00 |
1.00 |
1.00 |
1 |
| 212247_at2, 3
|
U133-A |
1 |
1.00 |
1.00 |
-- |
-- |
AW008531 |
0.80 |
1.00 |
0.91 |
1 |
| 222382_x_at2, 3
|
U133-A |
1 |
0.46 |
1.00 |
-- |
-- |
AW206115 |
0.40 |
1.00 |
0.76 |
1 |
| 212247_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 222382_x_at2
|
U133Plus2 |
1 |
0.46 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
NUP205 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: ATTTAGACCA
SOURCE GeneReport for Unigene cluster: Hs.727517
Expression variation in blood from EXPOLDB for NUP205 SABiosciences Custom PCR Arrays for NUP205
|
Orthologs
for NUP205 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for NUP205 gene from 5/15 species (see all 15)
About this table Species with no ortholog for NUP205
ENSEMBL Gene Tree for NUP205 (if available) |
Paralogs
for NUP205 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| -- |
Genomic Variants
for NUP205 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 7 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for NUP205 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for NUP205
2 CNVs: 100132 44290 | | QIAGEN SeqTarget long-range PCR primers for resequencing NUP205 |
|
Disorders & Mutations
for NUP205 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Medical News
for NUP205 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for NUP205 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
10/17 PubMed articles for NUP205 gene, integrated from 7 sources (see all 17):
(articles sorted by number of sources associating them with NUP205)- Nup93, a vertebrate homologue of yeast Nic96p, forms a complex with a novel 205-kDa protein and is required for correct nuclear pore assembly. (PubMed id 9348540)1, 2, 3 Grandi P....Hurt E. (1997)
- Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PubMed id 9039502)1, 2, 3 Nagase T....Nomura N. (1996)
- Vertebrate Nup53 interacts with the nuclear lamina and is required for the assembly of a Nup93-containing complex. (PubMed id 15703211)1, 2, 7 Hawryluk-Gara L.A.... Wozniak R.W. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Network organization of the human autophagy system. (PubMed id 20562859)1 Behrends C....Harper J.W. (2010)
- Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (2009)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- Defining the human deubiquitinating enzyme interactio n landscape. (PubMed id 19615732)1 Sowa M.E....Harper J.W. (2009)
- Evaluation of the low-specificity protease elastase for large-scale phosphoproteome analysis. (PubMed id 19007248)2 Wang B.... Korner R. (2008)
- Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)2 Daub H.... Mann M. (2008)
|
External Searches for NUP205 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NUP205 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NUP205 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing NUP205 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for NUP205 gene:
Search GeneIP for patents involving NUP205
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NUP205 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
 | |
 |
| | | |
 |
 |
| | |
 |  |  |  | |
| |  | Search Tocris compounds for NUP205 |
| |  |  |  |  | | | | |
 | | |
|
|
