Aliases &
Descriptions
for OR10H2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| olfactory receptor, family 10, subfamily H, member 21 2 | | Olfactory receptor OR19-232 3 | | MGC1383832 | | olfactory receptor 10H22 |
Export aliases for OR10H2 gene to outside databasesPrevious GC identifers: GC19M016330 GC19P016232 GC19P015684 GC19P015699 |
Summaries
for OR10H2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for OR10H2:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers theperception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors(GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with manyneurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction ofodorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to theolfactory receptor genes and proteins for this organism is independent of other organisms. (provided by RefSeq)
UniProtKB/Swiss-Prot: O10H2_HUMAN, O60403Function: Odorant receptor (Potential)
Gene Wiki entry for OR10H2 |
Genomic Views
for OR10H2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the OR10H2 gene promoter:
Pax-2 RP58 ITF-2 Tal-1beta MIF-1 LCR-F1 SREBP-1a SREBP-1b ZID SREBP-1c
Other transcription factors
Search SABiosciences Chromatin IP Primers for OR10H2
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.1 Ensembl cytogenetic band: 19p13.12 HGNC cytogenetic band: 19p13.1OR10H2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P015838: view genomic region
(about GC identifiers)
Start:
|
15,838,854 bp from pter |
End:
|
15,839,798 bp from pter |
Size:
|
945 bases |
Orientation:
|
plus strand |
RefSeq DNA sequence:- NC_000019.9 NT_011295.11
|
Proteins
for OR10H2 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: O10H2_HUMAN, O60403 (See
protein sequence)Recommended Name: Olfactory receptor 10H2 Size: 315 amino acids; 34663 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Secondary accessions: Q6IFQ1 Q96R58Explore the universe of human proteins at neXtProt for OR10H2: NX_O60403
REFSEQ proteins: NP_039227.1
ENSEMBL proteins: ENSP00000306095
Human Recombinant Proteins
2 Gene Ontology (GO) cellular component terms (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005886 | plasma membrane |
TAS | -- | | GO:0016021 | integral to membrane |
IEA | -- |
About this table
OR10H2 for ontologies About GeneDecksing
Antibodies for OR10H2:
Assays for OR10H2: |
Protein
Domains/
Families
for OR10H2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
OR10H2 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O60403ProtoNet protein and cluster: O60403 1 Blocks protein family: IPB000725 Olfactory receptor signature
UniProtKB/Swiss-Prot: O10H2_HUMAN, O60403Similarity: Belongs to the G-protein coupled receptor 1 family |
Gene Function
for OR10H2 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
UniProtKB/Swiss-Prot: O10H2_HUMAN, O60403Function: Odorant receptor (Potential)
Genatlas biochemistry entry for OR10H2:olfactory receptor,family 10,subfamily H,member 2,G protein coupled receptor superfamily2 Gene Ontology (GO) molecular function terms (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004872 | receptor activity |
IEA | -- | | GO:0004984 | olfactory receptor activity |
IEA | -- |
About this table
OR10H2 for ontologies About GeneDecksing
|
Pathways & Interactions
for OR10H2 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
OR10H2 for pathways About GeneDecksing
1  Kegg Pathway (Kegg details for OR10H2):
SABiosciences Custom Pathway-Focused PCR Arrays for OR10H2
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for OR10H2
5/191 Interacting proteins for OR10H2 (ENSP000003060953) via UniProtKB, MINT, and/or STRING (see all 191)About this table
3 Gene Ontology (GO) biological process terms (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007186 | G-protein coupled receptor protein signaling pathway |
-- | -- | | GO:0007608 | sensory perception of smell |
IEA | -- | | GO:0050896 | response to stimulus |
IEA | -- |
About this table
OR10H2 for ontologies About GeneDecksing
|
Drugs & Compounds
for OR10H2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for OR10H2
|
Transcripts
for OR10H2 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for OR10H2 gene: NM_013939.2 Additional cDNA sequence: BC069085.1 BC069457.1 BC112178.1 BC113647.1 1 DOTS entry: DT.91749326 7 AceView cDNA sequences: BC069457 NM_013939 BV173409 BC069085 BG197640 BG189045 BG194244
 highest scoring ESTs for OR10H2:BC069085 BC069457 BG194244 BG197640 NM_013939 BC112178 BC113647 BG189045 Unigene Cluster for OR10H2: Olfactory receptor, family 10, subfamily H, member 2 Hs.247694 [show with all ESTs]Unigene Representative Sequence: BC112178
GeneLoc Exon Structure
1 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000305899(uc002nbm.2)
|
Expression
for OR10H2 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| OR10H2 expression in normal and diseased human tissues
1 / 2 / 3 2 probe-sets matching OR10H2 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 208543_at2, 3
|
U133-A |
1 |
0.55 |
1.00 |
-- |
-- |
NM_013939 |
0.60 |
1.00 |
0.82 |
1 |
| 208543_at2
|
U133Plus2 |
1 |
0.55 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.247694
SABiosciences Custom PCR Arrays for OR10H2
|
Orthologs
for OR10H2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for OR10H2 gene from 4 species
About this table Species with no ortholog for OR10H2
ENSEMBL Gene Tree for OR10H2 (if available) |
Paralogs
for OR10H2 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for OR10H2 gene
- OR10V12 OR10H42 OR10W12 OR10H32 OR10H52 OR10Q12 OR10H12
OR10H2 for paralogs About GeneDecksing
|
Genomic Variants
for OR10H2 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for OR10H2
3 CNVs: 3181 29687 8864
1 Inversion: 43709 | | QIAGEN SeqTarget long-range PCR primers for resequencing OR10H2 |
|
Disorders & Mutations
for OR10H2 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Medical News
for OR10H2 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for OR10H2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
5 PubMed articles for OR10H2 gene integrated from 7 sources:
(articles sorted by number of sources associating them with OR10H2)- The human olfactory receptor gene family. (PubMed id 14983052)1, 2 Malnic B.... Buck L.B. (2004)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- DEFOG: a practical scheme for deciphering families of genes. (PubMed id 12213199)1, 2 Fuchs T.... Shamir R. (2002)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for OR10H2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing OR10H2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing OR10H2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing OR10H2 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| HORDE entry for OR10H2 | The Human Olfactory Receptor Data Explorer at the Weizmann Institute of Science |
|
| | |
About This Section
| Patent Information for OR10H2 gene:
Search GeneIP for patents involving OR10H2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for OR10H2 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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