Aliases &
Descriptions
for PAGE5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| P antigen family, member 5 (prostate associated)1 2 | | G antigen, family E, 12 | | CT16.11 2 3 | | cancer/testis antigen family 16, member 12 | | PAGE-51 2 3 | | OTTHUMP000000234002 | | CT16.21 2 | | G antigen family E member 12 | | Cancer/testis antigen 16.12 3 | | cancer/testis antigen family 16, member 22 | | Prostate-associated gene 5 protein2 3 | | CT162 | | GAGEE12 3 | | |
Export aliases for PAGE5 gene to outside databasesPrevious GC identifers: GC0XP055130 GC0XP055263 |
Summaries
for PAGE5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PAGE5:
This gene is a member of the GAGE family, which is expressed in a variety of tumors and in some fetal and reproductivetissues. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. It may alsobelong to a family of CT (cancer-testis) antigens. Multiple alternatively spliced transcript variants encodingdistinct isoforms have been found for this gene, but the biological validity of some variants have not beendetermined. (provided by RefSeq)
|
Genomic Views
for PAGE5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for PAGE5
Other transcription factors
Search SABiosciences Chromatin IP Primers for PAGE5
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xp11.21 Ensembl cytogenetic band: Xp11.21 HGNC cytogenetic band: Xp11.22PAGE5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP052295: view genomic region
(about GC identifiers)
Start:
|
52,295,627 bp from pter |
End:
|
52,299,377 bp from pter |
Size:
|
3,751 bases |
Orientation:
|
plus strand |
1 alternative location:
| ChrX+ 55,246,788-55,250,541 |
RefSeq DNA sequence:- NC_000023.10 NT_011630.14
|
Proteins
for PAGE5 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: GGEE1_HUMAN, Q96GU1 (See
protein sequence)Recommended Name: G antigen family E member 1 Size: 130 amino acids; 14046 Da
Secondary accessions: Q8WWL9Explore the universe of human proteins at neXtProt for PAGE5: NX_Q96GU1
REFSEQ proteins (2 alternative transcripts):
NP_001013453.1 NP_569734.2
ENSEMBL proteins: ENSP00000289619 ENSP00000406149 ENSP00000379481 ENSP00000364093 ENSP00000364090
Human Recombinant Proteins
Antibodies for PAGE5:
Assays for PAGE5: |
Protein
Domains/
Families
for PAGE5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PAGE5 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96GU1ProtoNet protein and cluster: Q96GU1 1 Blocks protein family: IPB008625 GAGE
UniProtKB/Swiss-Prot: GGEE1_HUMAN, Q96GU1Similarity: Belongs to the GAGE family |
Gene Function
for PAGE5 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
|
Pathways & Interactions
for PAGE5 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for PAGE5
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PAGE5
|
Drugs & Compounds
for PAGE5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for PAGE5
|
Transcripts
for PAGE5 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for PAGE5 gene (2 alternative transcripts): NM_001013435.1 NM_130467.3 Additional cDNA sequence: AJ344352.1 BC009230.2 BC110803.1 2 DOTS entries: DT.92420663 DT.92420665 24/25 AceView cDNA sequences (see all 25): AW135330 BQ437151 BE896256 BX088870 BF062128 BE408094 BE386043 AW205230 AA824398 BE386042 AJ344352 BP429046 BF026605 BC009230 BF026249 BF026248 BQ425920 NM_130467 BE410403 BE896742 BU156217 BG333836 BG477487 BF026873
 highest scoring ESTs for PAGE5:AJ344352 BC009230 BE386042 BE408094 BF026248 BF026293 BF026605 AW135330 AW205230 BE386043 Unigene Cluster for PAGE5: P antigen family, member 5 (prostate associated) Hs.668491 [show with all ESTs]Unigene Representative Sequence: BF026248
GeneLoc Exon Structure
5 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000289619(uc004duj.2 uc004duk.2) ENST00000453343 ENST00000396178
ENST00000374955 ENST00000374952
|
Expression
for PAGE5 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| PAGE5 expression in normal and diseased human tissues
1 / 2 / 3 3 probe-sets matching PAGE5 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 54512_s_at2, 3
|
U95-C |
4 |
0.94 |
0.43 |
1.00 |
1.00 |
AA824398 |
0.80 |
0.83 |
0.82 |
1 |
| 236152_at2, 3
|
U133-B |
1 |
0.82 |
1.00 |
-- |
-- |
AW135330 |
0.60 |
1.00 |
0.82 |
1 |
| 236152_at2
|
U133Plus2 |
1 |
0.82 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
PAGE5 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: TAACAAGATC
SOURCE GeneReport for Unigene cluster: Hs.668491
SABiosciences Custom PCR Arrays for PAGE5
|
Orthologs
for PAGE5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for PAGE5 gene from 1 species
| Organism |
Gene |
Locus |
Description |
Human
Similarity |
NCBI accessions |
chimpanzee
(Pan troglodytes) |
PAGE51 |
-- |
P antigen family, member 5 (prostate associated) |
97.64(n)
94.69(a) |
465659 XM_521084.2 XP_521084.2 |
About this table Species with no ortholog for PAGE5
ENSEMBL Gene Tree for PAGE5 (if available) |
Paralogs
for PAGE5 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for PAGE5 gene
- PAGE22 PAGE2B2 PAGE32 PAGE42
PAGE5 for paralogs About GeneDecksing
|
Genomic Variants
for PAGE5 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr X pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for PAGE5 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for PAGE5
1 CNV: 23256 | | QIAGEN SeqTarget long-range PCR primers for resequencing PAGE5 |
|
Disorders & Mutations
for PAGE5 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Medical News
for PAGE5 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for PAGE5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
5 PubMed articles for PAGE5 gene integrated from 7 sources:
(articles sorted by number of sources associating them with PAGE5)- The XAGE family of cancer/testis-associated genes: alignment and expression profile in normal tissues, melanoma lesions and Ewing's sarcoma. (PubMed id 11992404)1, 2, 3 Zendman A.J.W....van Muijen G.N.P. (2002)
- The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Identification of cancer/testis genes by database mining and mRNA expression analysis. (PubMed id 11920606)1, 3 Scanlan M.J....Old L.J. (2002)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for PAGE5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PAGE5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PAGE5 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PAGE5 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for PAGE5 gene:
Search GeneIP for patents involving PAGE5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for PAGE5 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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