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PFDN1 Gene

protein-coding GIFtS: 52

GC05M134769

prefoldin subunit 1
(Previous name: prefoldin 1 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

		Products

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases & Descriptions
prefoldin subunit 1¹ ²
PFD1¹ ² ³
prefoldin 1¹ ²
PDF²

External Ids:	HGNC: 8866¹	Entrez Gene: 5201²	Ensembl: ENSG00000113068⁷	UniProtKB: O60925³

Export aliases for PFDN1 gene to outside databases

Previous GC identifers: GC05M139447 GC05M140207 GC05M139607 GC05M139653 GC05M139604

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for PFDN1:

This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of

prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing

them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel

assembly with six protruding coiled-coils. (provided by RefSeq)

UniProtKB/Swiss-Prot: PFD1_HUMAN, O60925

Function: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent

polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative

proteins

Gene Wiki entry for PFDN1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the PFDN1 gene promoter:
         Bach1   Hlf   FOXJ2 (long isoform)   POU2F1   Pbx1a   Cdc5   NF-1   TBP   E4BP4   Elk-1
         Other transcription factors

Search SABiosciences Chromatin IP Primers for PFDN1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q31 Ensembl cytogenetic band: 5q31.3 HGNC cytogenetic band: 5q31

PFDN1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PFDN1 gene location

GeneLoc gene densities for chromosome 5 GeneLoc Exon Structure

GeneLoc location for GC05M134769: view genomic region (about GC identifiers)

Start:	134,769,914 bp from pter
End:	134,827,849 bp from pter
Size:	57,936 bases
Orientation:	minus strand

1 alternative location:

Chr5- 139,624,624-139,682,706

RefSeq DNA sequence:

NC_000005.9 NT_029289.11

(According to ¹UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

UniProtKB/Swiss-Prot: PFD1_HUMAN, O60925 (See protein sequence)

Recommended Name: Prefoldin subunit 1

Size: 122 amino acids; 14210 Da

Subunit: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits

Secondary accessions: B2RD02 Q53F95 Q96EX6

Explore the universe of human proteins at neXtProt for PFDN1: NX_O60925

REFSEQ proteins: NP_002613.2

ENSEMBL proteins:

ENSP00000261813 ENSP00000426383 ENSP00000428707

Human Recombinant Proteins

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3 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	--	--
GO:0005886	plasma membrane	--	--
GO:0016272	prefoldin complex	IEA	--

About this table

PFDN1 for ontologies About GeneDecksing

Antibodies for PFDN1:

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	Uscn ELISAs and CLIAs for PFDN1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

PFDN1 for domains About GeneDecksing

2 InterPro domains/families:

IPR002777 PFD_beta-like

IPR009053 Prefoldin

Graphical View of Domain Structure for InterPro Entry O60925

ProtoNet protein and cluster: O60925

1 Blocks protein family: IPB002777 Prefoldin-related KE2 protein

UniProtKB/Swiss-Prot: PFD1_HUMAN, O60925

Similarity: Belongs to the prefoldin subunit beta family

(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: PFD1_HUMAN, O60925

Function: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent

polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative

proteins

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Browse Nano Scale siRNA at Sigma-Aldrich Sigma-Aldrich esiRNA and siRNA for PFDN1 Sigma-Aldrich shRNA for PFDN1
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miRNA:		Sigma-Aldrich microRNA Mimics for PFDN1 Browse microRNA target validation systems at Sigma-Aldrich
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of PFDN1
		Search SABiosciences for Assays for microRNAs that regulate PFDN1

Gene
Editing:

Browse CompoZr Knockout ZFN at Sigma-Aldrich

Clones:		Browse Clones for the Expression of Recombinant Proteins Available from Millipore
		Browse iPSC Reprogramming Factors at Sigma-Aldrich
		OriGene GFP tagged cDNA clones in CMV expression vector: PFDN1 OriGene Myc/DDK tagged cDNA clones in CMV expression vector: PFDN1 OriGene untagged cDNA clones in CMV expression vector: PFDN1 OriGene 3'-UTR clone: PFDN1 Browse MicroRNA Expression Plasmids
		GenScript Custom cDNA clone Services for PFDN1
		Browse Sino Biological Human cDNA Clones

Cell
Lines:

GenScript Custom overexpressing Cell Line Services for PFDN1

Genatlas biochemistry entry for PFDN1:

prefoldin subunit 1,keratin homologous

3 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	sequence-specific DNA binding transcription factor activity	TAS	8744932
GO:0005515	protein binding	IPI	17353931
GO:0051082	unfolded protein binding	IEA	--

About this table

PFDN1 for ontologies About GeneDecksing

Animal Models: 7 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Pfdn1):

behavior/neurological	growth/size	hematopoietic system	immune system	life span-post-weaning/aging
nervous system	respiratory system

PFDN1 for phenotypes About GeneDecksing

(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section

SABiosciences Pathway-Focused PCR Array including PFDN1: PAHS-076A

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for PFDN1

5/40 Interacting proteins for PFDN1 (O60925^{1, 2} ENSP00000261813³) via UniProtKB, MINT, and/or STRING (see all 40)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
WDR8	Q9P2S5¹	EBI-356919,EBI-1054904
C1orf103	Q5T3J3²	MINT-63196
DEFA3	P59666²	MINT-63191
GIT1	Q9Y2X7²	MINT-63198
GPRASP1	Q5JY77²	MINT-63193

About this table

4 Gene Ontology (GO) biological process terms (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006457	protein folding	TAS	--
GO:0007049	cell cycle	TAS	8744932
GO:0044267	cellular protein metabolic process	TAS	--
GO:0051084	'de novo' posttranslational protein folding	TAS	--

About this table

PFDN1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse Small Molecules at Sigma-Aldrich

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for PFDN1

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Browse Nano Scale siRNA at Sigma-Aldrich Sigma-Aldrich esiRNA and siRNA for PFDN1 Sigma-Aldrich shRNA for PFDN1
		OriGene 29mer shRNA kits in GFP-retroviral vector: PFDN1 OriGene shRNA RFP: PFDN1 OriGene basic RS shRNA: PFDN1 OriGene siRNA: PFDN1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of PFDN1

miRNA:		Sigma-Aldrich microRNA Mimics for PFDN1 Browse microRNA target validation systems at Sigma-Aldrich
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of PFDN1
		Search SABiosciences for Assays for microRNAs that regulate PFDN1

Clones:		Browse FLAG tag genes at Sigma-Aldrich
		OriGene GFP tagged cDNA clones in CMV expression vector: PFDN1 OriGene Myc/DDK tagged cDNA clones in CMV expression vector: PFDN1 OriGene untagged cDNA clones in CMV expression vector: PFDN1 OriGene 3'-UTR Clone: PFDN1 Browse OriGene MicroRNA Expression Plasmids
		GenScript Custom cDNA clone Services for PFDN1

Primers:		OriGene genome-wide validated SYBR primer pairs: PFDN1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay for PFDN1: PPH12199A

REFSEQ mRNAs for PFDN1 gene:

NM_002622.4

Additional cDNA sequence:

AK093558.1 AK223394.1 AK315353.1 BC003620.1 BC006202.1 BC011869.2 CR597655.1 CR599219.1

CR603344.1 CR604906.1 CR605241.1 CR610512.1 CR613979.1 CR622770.1 CR623755.1 Y17392.1

19 DOTS entries:

DT.101974730 DT.100880577 DT.319565 DT.100880562 DT.92470190 DT.120860634 DT.120860658 DT.100880575

DT.95082069 DT.120867829 DT.100880580 DT.95334063 DT.100880581 DT.40129481 DT.92470195 DT.100880579

DT.120860629 DT.92004836 DT.95112501

24/538 AceView cDNA sequences (see all 538):

AI262235 BM703941 BM757872 AW244078 BM759424 BM680359 CD370365 BX477700

BI962964 BQ000726 AI871194 BU689578 CB853640 BQ001855 CB119788 AI337511

BM977715 CR604906 AW337534 AW117523 AI240235 BQ010123 BE893265 BQ614411

highest scoring ESTs for PFDN1:

D45333 AA147788 AA310532 AL536774 AV764327 AW160381 BC003620 BC006202 BC011869 BE249937

Unigene Cluster for PFDN1:

Prefoldin subunit 1

Hs.483564 [show with all ESTs]

Unigene Representative Sequence: AK093558

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for PFDN1

ExUns:	1a	·	1b	^	2	^	3a	·	3b	^	4a	·	4b
SP1:									-
SP2:					-				-
SP3:

About this scheme

ECgene alternative splicing isoforms for PFDN1
7 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000261813(uc003lfe.1 uc003lff.1 uc003lfg.1 uc003lfh.1)

ENST00000514611 ENST00000510217 ENST00000512707 ENST00000524074 ENST00000512925

ENST00000507185

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

PFDN1 expression in normal and diseased human tissues

¹ / ² / ³

3 probe-sets matching PFDN1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
39435_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	D45333	1.00	1.00	1.00	1
201507_at²^{, 3}	U133-A	1	0.73	1.00	--	--	NM_002622	0.60	1.00	0.82	1
201507_at²	U133Plus2	1	0.73	1.00	--	--	--	--	--	--	--

About this table

PFDN1 for expression About GeneDecksing

Data from Genenote (Publications) and GNF BioGPS
About these images

PFDN1 gene electronic northern expression

About these images

CGAP SAGE TAG: CAGTAGACAG

SOURCE GeneReport for Unigene cluster: Hs.483564

Expression variation in blood from EXPOLDB for PFDN1

Primers:		OriGene genome-wide validated SYBR primer pairs: PFDN1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay for PFDN1: PPH12199A

SABiosciences Expression via Pathway-Focused PCR Array including PFDN1: PAHS-076A

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for PFDN1 gene from 5/10 species (see all 10)

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	LOC490658¹	--	similar to prefoldin 1	95.63(n) 99.18(a)	490658 XM_547780.2 XP_547780.2
chimpanzee (Pan troglodytes)	PFDN1¹	--	prefoldin subunit 1	99.73(n) 99.18(a)	462112 XM_517971.2 XP_517971.1
cow (Bos taurus)	PFDN1¹	--	prefoldin subunit 1	92.62(n) 98.36(a)	616553 XM_001251399.1 XP_001251400.1
rat (Rattus norvegicus)	Pfdn1¹	--	prefoldin 1	91.26(n) 97.54(a)	361310 XM_341596.3 XP_341597.3
mouse (Mus musculus)	Pfdn1^{1 , 5}	18 (19.46 cM)⁵	prefoldin 1^{1, 5}	91.26(n)¹ 97.54(a)¹	67199¹ NM_026027.2¹ NP_080303.1¹ AA408327⁵ AI853247⁵ (see all 17)

About this table Species with no ortholog for PFDN1

ENSEMBL Gene Tree for PFDN1 (if available)

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(SNPs according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

SNP ID	Valid	Chr 5 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample
Genomic Data				Transcription Related Data				Allele Frequencies
			--	--	--		--	--
rs7203^1,2	C,A	139624870(-)	`CCTTTT/CGGCCA`	1	--	ut3¹		3	MN NA	188
rs7204^1,2	C,A	139624864(-)	`GGCCAA/GTATCA`	1	--	ut3¹ ese³		3	MN NA	188
rs9042^1,2	C,F,A,	139625347(-)	`GACACT/GCTTCC`	1	--	ut3¹ ese³ trp³		13	MN EA NS NA	2700
rs968255^1,2	H	139677105(+)	`CCCGGT/GGAGAT`	1	--	int¹		4	NS EA	420
rs1030667^1,2	C,F,A,	139658794(-)	`ATCCAA/CATGTC`	1	--	int¹		18	NA EA NS WA	1270
rs1347143^1,2	C,F,O,A,	139669386(+)	`ATCTCG/AACTTC`	1	--	int¹		17	MN NS EA NA WA	1184
rs1432875^1,2	C,F,A,	139667189(+)	`tgcagT/Catgag`	1	--	int¹		1	WA	50
rs1529693^1,2	C,F,A,	139678213(+)	`AAAAAA/GGTGAA`	1	--	int¹ trp³		13	NS EA NA WA	772
rs1864970^1,2	C,F,A,	139633042(+)	`TTAGCT/CGCTCG`	1	--	int¹		16	MN NA NS EA WA	956
rs2014350^1,2	C,A,H,	139659315(-)	`gccacC/Tgcgcc`	1	--	int¹		4	NA WA	8

About this table

HapMap Linkage Disequilibrium images for PFDN1 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for PFDN1: --

QIAGEN SeqTarget long-range PCR primers for resequencing PFDN1

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section

PFDN1 for disorders About GeneDecksing

OMIM: 604897

Export disorders and mutations for PFDN1 gene to outside databases

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶UniProtKB/TrEMBL, and/or ⁷Novoseek)
About This Section

10/23 PubMed articles for PFDN1 gene, integrated from 7 sources (see all 23):
(articles sorted by number of sources associating them with PFDN1)

Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin. (PubMed id 9630229)^{1, 2, 3} Vainberg I.E....Cowan N.J. (1998)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Expression, cellular distribution and protein binding of the glioma amplified sequence (GAS41), a highly conserved putative transcription factor. (PubMed id 11521196)^{1, 7} Munnia A.... Meese E. (2001)
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)² Gauci S....Mohammed S. (2009)
Defining the human deubiquitinating enzyme interactio n landscape. (PubMed id 19615732)¹ Sowa M.E....Harper J.W. (2009)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)¹ Barbe L....Andersson-Svahn H. (2008)
Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931)¹ Ewing R.M.... Figeys D. (2007)
PhLP3 modulates CCT-mediated actin and tubulin folding via ternary complexes with substrates. (PubMed id 16415341)¹ Stirling P.C.... Leroux M.R. (2006)
A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)¹ Stelzl U.... Wanker E.E. (2005)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 5201	HGNC: 8866	AceView: PFDN1	Ensembl:ENSG00000113068	euGenes: HUgn5201
ECgene: PFDN1	H-InvDB: PFDN1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Intellectual Property for PFDN1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from XenneX, Inc.)

About This Section

Patent Information for PFDN1 gene:
Search GeneIP for patents involving PFDN1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
About This Section

	Millipore Custom Antibody & Bulk Services
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	Predesigned and custom siRNAs for PFDN1		Antibodies for PFDN1
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	Lysates
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	siRNA
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	Fluorogenic Cell Assay Kits
	miRNA Primers for qPCR Assays
	3' UTR Clones for miRNA Target Studies
	miRNA Expression Plasmids

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of PFDN1
	SeqTarget long-range PCR primers for resequencing PFDN1
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing of PFDN1

	GenScript Custom Purified and Recombinant Proteins Services for PFDN1		GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for PFDN1
	GenScript Custom Assay Services for PFDN1		GenScript Custom Superior Antibodies Services for PFDN1
	GenScript Custom overexpressing Cell Line Services for PFDN1		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

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Browse antibodies at Epitomics

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ELISAs and CLIAs for PFDN1

GeneCards Homepage - Last full update: 31 Dec 2010 - Incremental updates: 9 Jan 2011 , 10 Jan 2011

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The GeneCards human gene database gene index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

PFDN1 gene at Home site.

hostname: www-ab3 db genecards_305 index build: 81e solr: 1.4

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PFDN1 Gene

protein-coding GIFtS: 52

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PFDN1 Gene

protein-coding GIFtS: 52

Aliases & Descriptionsfor PFDN1 gene

Summariesfor PFDN1 gene

Genomic Viewsfor PFDN1 gene

Proteinsfor PFDN1 gene

Protein Domains/Familiesfor PFDN1 gene

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Genome Databases showing PFDN1 gene

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Aliases &
Descriptions
for PFDN1 gene

Summaries
for PFDN1 gene

Genomic Views
for PFDN1 gene

Proteins
for PFDN1 gene

Protein Domains/
Families
for PFDN1 gene

Gene Function
for PFDN1 gene

Pathways & Interactions
for PFDN1 gene

Drugs & Compounds
for PFDN1 gene

Transcripts
for PFDN1 gene

Expression
for PFDN1 gene

Orthologs
for PFDN1 gene

Paralogs
for PFDN1 gene

Genomic Variants
for PFDN1 gene

Disorders & Mutations
for PFDN1 gene

Medical News
for PFDN1 gene

Publications
for PFDN1 gene

Intellectual Property
for PFDN1 gene

Products
for PFDN1 gene